Compile Data Set for Download or QSAR
Report error Found 48 Enz. Inhib. hit(s) with all data for entry = 50015976
TargetSerine/threonine-protein kinase Chk2(Human)
Johnson & Johnson Pharmaceutical Research and Development

Curated by ChEMBL
LigandPNGBDBM50163251(2-(4-(4-hydroxyphenylthio)phenyl)-1H-benzo[d]imida...)
Affinity DataIC50: 2.30nMAssay Description:Inhibition of recombinant human Chk2 kinaseMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetSerine/threonine-protein kinase Chk2(Human)
Johnson & Johnson Pharmaceutical Research and Development

Curated by ChEMBL
LigandPNGBDBM50163246(2-[4-(3,4-Dichloro-phenylsulfamoyl)-phenyl]-1H-ben...)
Affinity DataIC50: 3.40nMAssay Description:Inhibition of recombinant human Chk2 kinaseMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetSerine/threonine-protein kinase Chk2(Human)
Johnson & Johnson Pharmaceutical Research and Development

Curated by ChEMBL
LigandPNGBDBM50163259(2-[4-(3-Chloro-4-methyl-phenoxy)-phenyl]-1H-benzoi...)
Affinity DataIC50: 4.40nMAssay Description:Inhibition of recombinant human Chk2 kinaseMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetSerine/threonine-protein kinase Chk2(Human)
Johnson & Johnson Pharmaceutical Research and Development

Curated by ChEMBL
LigandPNGBDBM50163254(2-[4-(4-Chloro-3-trifluoromethyl-phenoxy)-phenyl]-...)
Affinity DataIC50: 4.5nMAssay Description:Inhibition of recombinant human Chk2 kinaseMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetSerine/threonine-protein kinase Chk2(Human)
Johnson & Johnson Pharmaceutical Research and Development

Curated by ChEMBL
LigandPNGBDBM50163266(2-[4-(3,4-Dichloro-phenoxy)-phenyl]-1H-benzoimidaz...)
Affinity DataIC50: 5.5nMAssay Description:Inhibition of recombinant human Chk2 kinaseMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetSerine/threonine-protein kinase Chk2(Human)
Johnson & Johnson Pharmaceutical Research and Development

Curated by ChEMBL
LigandPNGBDBM50163264(2-[4-(4-Chloro-benzenesulfonyl)-phenyl]-1H-benzoim...)
Affinity DataIC50: 6.60nMAssay Description:Inhibition of recombinant human Chk2 kinaseMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetSerine/threonine-protein kinase Chk2(Human)
Johnson & Johnson Pharmaceutical Research and Development

Curated by ChEMBL
LigandPNGBDBM50163255(2-[4-(4-Chloro-phenylsulfanyl)-phenyl]-1H-benzoimi...)
Affinity DataIC50: 8.20nMAssay Description:Inhibition of recombinant human Chk2 kinaseMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetSerine/threonine-protein kinase Chk2(Human)
Johnson & Johnson Pharmaceutical Research and Development

Curated by ChEMBL
LigandPNGBDBM50163282(2-[4-(4-Chloro-3-hydroxy-phenoxy)-phenyl]-1H-benzo...)
Affinity DataIC50: 9.80nMAssay Description:Inhibition of recombinant human Chk2 kinaseMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetSerine/threonine-protein kinase Chk2(Human)
Johnson & Johnson Pharmaceutical Research and Development

Curated by ChEMBL
LigandPNGBDBM50163278(2-[4-(Naphthalen-2-yloxy)-phenyl]-1H-benzoimidazol...)
Affinity DataIC50: 12nMAssay Description:Inhibition of recombinant human Chk2 kinaseMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetSerine/threonine-protein kinase Chk2(Human)
Johnson & Johnson Pharmaceutical Research and Development

Curated by ChEMBL
LigandPNGBDBM50163270(2-[4-(2-Fluoro-5-trifluoromethyl-phenoxy)-phenyl]-...)
Affinity DataIC50: 12nMAssay Description:Inhibition of recombinant human Chk2 kinaseMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetSerine/threonine-protein kinase Chk2(Human)
Johnson & Johnson Pharmaceutical Research and Development

Curated by ChEMBL
LigandPNGBDBM50163250(2-[4-(3,4-Dimethyl-phenoxy)-phenyl]-1H-benzoimidaz...)
Affinity DataIC50: 12nMAssay Description:Inhibition of recombinant human Chk2 kinaseMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetSerine/threonine-protein kinase Chk2(Human)
Johnson & Johnson Pharmaceutical Research and Development

Curated by ChEMBL
LigandPNGBDBM50163269(2-[4-(4-Chloro-benzenesulfinyl)-phenyl]-1H-benzoim...)
Affinity DataIC50: 13nMAssay Description:Inhibition of recombinant human Chk2 kinaseMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetSerine/threonine-protein kinase Chk2(Human)
Johnson & Johnson Pharmaceutical Research and Development

Curated by ChEMBL
LigandPNGBDBM50163273(2-[4-(4-Chloro-phenylsulfamoyl)-phenyl]-1H-benzoim...)
Affinity DataIC50: 14nMAssay Description:Inhibition of recombinant human Chk2 kinaseMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetSerine/threonine-protein kinase Chk2(Human)
Johnson & Johnson Pharmaceutical Research and Development

Curated by ChEMBL
LigandPNGBDBM34064(CHEMBL179583 | 2-arylbenzimidazole)
Affinity DataIC50: 15nMAssay Description:Inhibition of recombinant human Chk2 kinaseMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetSerine/threonine-protein kinase Chk2(Human)
Johnson & Johnson Pharmaceutical Research and Development

Curated by ChEMBL
LigandPNGBDBM34064(CHEMBL179583 | 2-arylbenzimidazole)
Affinity DataIC50: 16nMAssay Description:Inhibition of recombinant human Chk2 kinaseMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetSerine/threonine-protein kinase Chk2(Human)
Johnson & Johnson Pharmaceutical Research and Development

Curated by ChEMBL
LigandPNGBDBM50163271(2-[4-(3-Chloro-phenoxy)-phenyl]-1H-benzoimidazole-...)
Affinity DataIC50: 17nMAssay Description:Inhibition of recombinant human Chk2 kinaseMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetSerine/threonine-protein kinase Chk2(Human)
Johnson & Johnson Pharmaceutical Research and Development

Curated by ChEMBL
LigandPNGBDBM50163274(2-(4-Phenylsulfamoyl-phenyl)-1H-benzoimidazole-5-c...)
Affinity DataIC50: 18nMAssay Description:Inhibition of recombinant human Chk2 kinaseMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetSerine/threonine-protein kinase Chk2(Human)
Johnson & Johnson Pharmaceutical Research and Development

Curated by ChEMBL
LigandPNGBDBM50163260(2-[4-(4-Methoxy-phenoxy)-phenyl]-1H-benzoimidazole...)
Affinity DataIC50: 23nMAssay Description:Inhibition of recombinant human Chk2 kinaseMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetSerine/threonine-protein kinase Chk2(Human)
Johnson & Johnson Pharmaceutical Research and Development

Curated by ChEMBL
LigandPNGBDBM50163277(2-(4-p-Tolyloxy-phenyl)-1H-benzoimidazole-5-carbox...)
Affinity DataIC50: 24nMAssay Description:Inhibition of recombinant human Chk2 kinaseMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetSerine/threonine-protein kinase Chk2(Human)
Johnson & Johnson Pharmaceutical Research and Development

Curated by ChEMBL
LigandPNGBDBM50163249(2-[4-(3,4-Dimethoxy-phenoxy)-phenyl]-1H-benzoimida...)
Affinity DataIC50: 31nMAssay Description:Inhibition of recombinant human Chk2 kinaseMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetSerine/threonine-protein kinase Chk2(Human)
Johnson & Johnson Pharmaceutical Research and Development

Curated by ChEMBL
LigandPNGBDBM50163253(2-(4-Benzyloxy-phenyl)-1H-benzoimidazole-5-carboxy...)
Affinity DataIC50: 32nMAssay Description:Inhibition of recombinant human Chk2 kinaseMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetSerine/threonine-protein kinase Chk2(Human)
Johnson & Johnson Pharmaceutical Research and Development

Curated by ChEMBL
LigandPNGBDBM50163287(2-[4-(4-Methanesulfonylamino-phenoxy)-phenyl]-1H-b...)
Affinity DataIC50: 41nMAssay Description:Inhibition of recombinant human Chk2 kinaseMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetSerine/threonine-protein kinase Chk2(Human)
Johnson & Johnson Pharmaceutical Research and Development

Curated by ChEMBL
LigandPNGBDBM50163261(2-[4-(4-Carbamoyl-phenoxy)-phenyl]-1H-benzoimidazo...)
Affinity DataIC50: 47nMAssay Description:Inhibition of recombinant human Chk2 kinaseMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetSerine/threonine-protein kinase Chk2(Human)
Johnson & Johnson Pharmaceutical Research and Development

Curated by ChEMBL
LigandPNGBDBM50163284(2-(4-phenoxyphenyl)-1H-benzo[d]imidazole-5-carboxa...)
Affinity DataIC50: 55nMAssay Description:Inhibition of recombinant human Chk2 kinaseMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetSerine/threonine-protein kinase Chk2(Human)
Johnson & Johnson Pharmaceutical Research and Development

Curated by ChEMBL
LigandPNGBDBM50163285(2-[4-(3-Hydroxy-phenoxy)-phenyl]-1H-benzoimidazole...)
Affinity DataIC50: 61nMAssay Description:Inhibition of recombinant human Chk2 kinaseMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetSerine/threonine-protein kinase Chk2(Human)
Johnson & Johnson Pharmaceutical Research and Development

Curated by ChEMBL
LigandPNGBDBM50163275(2-[4-(4-Nitro-phenoxy)-phenyl]-1H-benzoimidazole-5...)
Affinity DataIC50: 81nMAssay Description:Inhibition of recombinant human Chk2 kinaseMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetSerine/threonine-protein kinase Chk2(Human)
Johnson & Johnson Pharmaceutical Research and Development

Curated by ChEMBL
LigandPNGBDBM50163252(2-Biphenyl-4-yl-1H-benzoimidazole-5-carboxylic aci...)
Affinity DataIC50: 100nMAssay Description:Inhibition of recombinant human Chk2 kinaseMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetSerine/threonine-protein kinase Chk2(Human)
Johnson & Johnson Pharmaceutical Research and Development

Curated by ChEMBL
LigandPNGBDBM50163268(2-Naphthalen-2-yl-1H-benzoimidazole-5-carboxylic a...)
Affinity DataIC50: 200nMAssay Description:Inhibition of recombinant human Chk2 kinaseMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetSerine/threonine-protein kinase Chk2(Human)
Johnson & Johnson Pharmaceutical Research and Development

Curated by ChEMBL
LigandPNGBDBM50163258(2-(4-Ethoxy-phenyl)-1H-benzoimidazole-5-carboxylic...)
Affinity DataIC50: 200nMAssay Description:Inhibition of recombinant human Chk2 kinaseMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetSerine/threonine-protein kinase Chk2(Human)
Johnson & Johnson Pharmaceutical Research and Development

Curated by ChEMBL
LigandPNGBDBM50163286(2-(4''-Chloro-biphenyl-4-yl)-1H-benzoimidazole-5-c...)
Affinity DataIC50: 250nMAssay Description:Inhibition of recombinant human Chk2 kinaseMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetSerine/threonine-protein kinase Chk2(Human)
Johnson & Johnson Pharmaceutical Research and Development

Curated by ChEMBL
LigandPNGBDBM50163276(2-(4-Phenoxy-phenyl)-1H-benzoimidazole-5-sulfonic ...)
Affinity DataIC50: 290nMAssay Description:Inhibition of recombinant human Chk2 kinaseMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetSerine/threonine-protein kinase Chk2(Human)
Johnson & Johnson Pharmaceutical Research and Development

Curated by ChEMBL
LigandPNGBDBM50163288(2-(4-Phenylcarbamoyl-phenyl)-1H-benzoimidazole-5-c...)
Affinity DataIC50: 410nMAssay Description:Inhibition of recombinant human Chk2 kinaseMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetSerine/threonine-protein kinase Chk2(Human)
Johnson & Johnson Pharmaceutical Research and Development

Curated by ChEMBL
LigandPNGBDBM50163262(2-Dibenzofuran-2-yl-1H-benzoimidazole-5-carboxylic...)
Affinity DataIC50: 500nMAssay Description:Inhibition of recombinant human Chk2 kinaseMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetSerine/threonine-protein kinase Chk2(Human)
Johnson & Johnson Pharmaceutical Research and Development

Curated by ChEMBL
LigandPNGBDBM50163247(2-[3-(3,4-Dichloro-phenoxy)-phenyl]-1H-benzoimidaz...)
Affinity DataIC50: 530nMAssay Description:Inhibition of recombinant human Chk2 kinaseMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetSerine/threonine-protein kinase Chk2(Human)
Johnson & Johnson Pharmaceutical Research and Development

Curated by ChEMBL
LigandPNGBDBM50163289(2-(4-Phenoxy-phenyl)-1H-benzoimidazole-5-carboxyli...)
Affinity DataIC50: 640nMAssay Description:Inhibition of recombinant human Chk2 kinaseMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetSerine/threonine-protein kinase Chk2(Human)
Johnson & Johnson Pharmaceutical Research and Development

Curated by ChEMBL
LigandPNGBDBM50163245(2-[4-(4-Chloro-phenylcarbamoyl)-phenyl]-1H-benzoim...)
Affinity DataIC50: 680nMAssay Description:Inhibition of recombinant human Chk2 kinaseMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetSerine/threonine-protein kinase Chk2(Human)
Johnson & Johnson Pharmaceutical Research and Development

Curated by ChEMBL
LigandPNGBDBM50163272(3-[4-(5-Carbamoyl-1H-benzoimidazol-2-yl)-phenoxy]-...)
Affinity DataIC50: 715nMAssay Description:Inhibition of recombinant human Chk2 kinaseMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetSerine/threonine-protein kinase Chk2(Human)
Johnson & Johnson Pharmaceutical Research and Development

Curated by ChEMBL
LigandPNGBDBM50163257(2-[4-(3-Diethylcarbamoyl-phenoxy)-phenyl]-1H-benzo...)
Affinity DataIC50: 820nMAssay Description:Inhibition of recombinant human Chk2 kinaseMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetSerine/threonine-protein kinase Chk2(Human)
Johnson & Johnson Pharmaceutical Research and Development

Curated by ChEMBL
LigandPNGBDBM50163290(2-(3-Phenoxy-phenyl)-1H-benzoimidazole-5-carboxyli...)
Affinity DataIC50: 930nMAssay Description:Inhibition of recombinant human Chk2 kinaseMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetSerine/threonine-protein kinase Chk2(Human)
Johnson & Johnson Pharmaceutical Research and Development

Curated by ChEMBL
LigandPNGBDBM50163263(2-p-Tolyl-1H-benzoimidazole-5-carboxylic acid amid...)
Affinity DataIC50: 1.10E+3nMAssay Description:Inhibition of recombinant human Chk2 kinaseMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetSerine/threonine-protein kinase Chk2(Human)
Johnson & Johnson Pharmaceutical Research and Development

Curated by ChEMBL
LigandPNGBDBM50163281(2-Phenyl-1H-benzoimidazole-5-carboxylic acid amide...)
Affinity DataIC50: 1.20E+3nMAssay Description:Inhibition of recombinant human Chk2 kinaseMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetSerine/threonine-protein kinase Chk2(Human)
Johnson & Johnson Pharmaceutical Research and Development

Curated by ChEMBL
LigandPNGBDBM50163256(2-(4-Phenoxy-phenyl)-1H-benzoimidazole-5-carboxyli...)
Affinity DataIC50: 1.40E+3nMAssay Description:Inhibition of recombinant human Chk2 kinaseMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetSerine/threonine-protein kinase Chk2(Human)
Johnson & Johnson Pharmaceutical Research and Development

Curated by ChEMBL
LigandPNGBDBM50163279(5-Nitro-2-(4-phenoxy-phenyl)-1H-benzoimidazole | C...)
Affinity DataIC50: 1.50E+3nMAssay Description:Inhibition of recombinant human Chk2 kinaseMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetSerine/threonine-protein kinase Chk2(Human)
Johnson & Johnson Pharmaceutical Research and Development

Curated by ChEMBL
LigandPNGBDBM50163265(2-(4-Phenoxy-phenyl)-1H-benzoimidazole-5-carbonitr...)
Affinity DataIC50: 1.90E+3nMAssay Description:Inhibition of recombinant human Chk2 kinaseMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetSerine/threonine-protein kinase Chk2(Human)
Johnson & Johnson Pharmaceutical Research and Development

Curated by ChEMBL
LigandPNGBDBM50163248(2-(4-Phenoxy-phenyl)-1H-benzoimidazol-5-ylamine | ...)
Affinity DataIC50: 2.40E+3nMAssay Description:Inhibition of recombinant human Chk2 kinaseMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetSerine/threonine-protein kinase Chk2(Human)
Johnson & Johnson Pharmaceutical Research and Development

Curated by ChEMBL
LigandPNGBDBM50163283(2-(4-Phenoxy-phenyl)-1H-benzoimidazole-4-carboxyli...)
Affinity DataIC50: 6.00E+3nMAssay Description:Inhibition of recombinant human Chk2 kinaseMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetSerine/threonine-protein kinase Chk2(Human)
Johnson & Johnson Pharmaceutical Research and Development

Curated by ChEMBL
LigandPNGBDBM50163267(2-(4-Phenoxy-phenyl)-1H-benzoimidazole-5-carboxyli...)
Affinity DataIC50: 1.00E+4nMAssay Description:Inhibition of recombinant human Chk2 kinaseMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetSerine/threonine-protein kinase Chk2(Human)
Johnson & Johnson Pharmaceutical Research and Development

Curated by ChEMBL
LigandPNGBDBM50163280(2-[4-(3,4-Dichloro-phenylcarbamoyl)-phenyl]-1H-ben...)
Affinity DataIC50: 1.00E+4nMAssay Description:Inhibition of recombinant human Chk2 kinaseMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed