Compile Data Set for Download or QSAR
Report error Found 12 Enz. Inhib. hit(s) with all data for entry = 50015773
TargetKappa-type opioid receptor(Human)
Adolor

Curated by ChEMBL
LigandPNGBDBM50093965(N-Methyl-N-((S)-1-phenyl-2-pyrrolidin-1-yl-ethyl)-...)
Affinity DataKi:  0.0580nMAssay Description:Displacement of bound [3H]diprenorphine from membranes expressing cloned human kappa opioid receptorMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetKappa-type opioid receptor(Human)
Adolor

Curated by ChEMBL
LigandPNGBDBM50160834(N-[(S)-1-(3-Amino-phenyl)-2-pyrrolidin-1-yl-ethyl]...)
Affinity DataKi:  0.310nMAssay Description:Displacement of bound [3H]diprenorphine from membranes expressing cloned human kappa opioid receptorMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetKappa-type opioid receptor(Human)
Adolor

Curated by ChEMBL
LigandPNGBDBM50160840(N-[(S)-1-(3-Methanesulfonylamino-phenyl)-2-pyrroli...)
Affinity DataKi:  0.360nMAssay Description:Displacement of bound [3H]diprenorphine from membranes expressing cloned human kappa opioid receptorMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetKappa-type opioid receptor(Human)
Adolor

Curated by ChEMBL
LigandPNGBDBM50160832(N-[1-(3-Hydroxy-phenyl)-2-pyrrolidin-1-yl-ethyl]-N...)
Affinity DataKi:  0.440nMAssay Description:Displacement of bound [3H]diprenorphine from membranes expressing cloned human kappa opioid receptorMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetKappa-type opioid receptor(Human)
Adolor

Curated by ChEMBL
LigandPNGBDBM50160842(N-[(S)-1-(3-aminosulfonylamino-phenyl)-2-pyrrolidi...)
Affinity DataKi:  0.480nMAssay Description:Displacement of bound [3H]diprenorphine from membranes expressing cloned human kappa opioid receptorMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetKappa-type opioid receptor(Human)
Adolor

Curated by ChEMBL
LigandPNGBDBM50160836(N-[1-(3-Methoxy-phenyl)-2-pyrrolidin-1-yl-ethyl]-N...)
Affinity DataKi:  0.530nMAssay Description:Displacement of bound [3H]diprenorphine from membranes expressing cloned human kappa opioid receptorMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetKappa-type opioid receptor(Human)
Adolor

Curated by ChEMBL
LigandPNGBDBM50160838(N-Methyl-N-[(S)-1-(3-nitro-phenyl)-2-pyrrolidin-1-...)
Affinity DataKi:  0.630nMAssay Description:Displacement of bound [3H]diprenorphine from membranes expressing cloned human kappa opioid receptorMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetKappa-type opioid receptor(Human)
Adolor

Curated by ChEMBL
LigandPNGBDBM83435(2-[3-[1-[2-(3,4-dichlorophenyl)ethanoyl-methyl-ami...)
Affinity DataKi:  2.69nMAssay Description:Displacement of bound [3H]diprenorphine from membranes expressing cloned human kappa opioid receptorMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetKappa-type opioid receptor(Human)
Adolor

Curated by ChEMBL
LigandPNGBDBM50160833([3-(1-{Methyl-[2-(4-trifluoromethyl-phenyl)-acetyl...)
Affinity DataKi:  2.90nMAssay Description:Displacement of bound [3H]diprenorphine from membranes expressing cloned human kappa opioid receptorMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetKappa-type opioid receptor(Human)
Adolor

Curated by ChEMBL
LigandPNGBDBM50160835([3-(1-{Methyl-[2-(4-trifluoromethyl-phenyl)-acetyl...)
Affinity DataKi:  3.70nMAssay Description:Displacement of bound [3H]diprenorphine from membranes expressing cloned human kappa opioid receptorMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetKappa-type opioid receptor(Human)
Adolor

Curated by ChEMBL
LigandPNGBDBM50160839(N-[3-((S)-1-{Methyl-[2-(4-trifluoromethyl-phenyl)-...)
Affinity DataKi:  9.5nMAssay Description:Displacement of bound [3H]diprenorphine from membranes expressing cloned human kappa opioid receptorMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetKappa-type opioid receptor(Human)
Adolor

Curated by ChEMBL
LigandPNGBDBM50160841({Carboxymethyl-[3-((S)-1-{methyl-[2-(4-trifluorome...)
Affinity DataKi:  2.30E+3nMAssay Description:Displacement of bound [3H]diprenorphine from membranes expressing cloned human kappa opioid receptorMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed