Compile Data Set for Download or QSAR
Report error Found 35 Enz. Inhib. hit(s) with all data for entry = 50000435
TargetPancreatic alpha-amylase(Rat)
Institute of Research

Curated by ChEMBL
LigandPNGBDBM50005681(CHEMBL286008 | 2-Cyclohexyl-2-phenyl-propionic aci...)
Affinity DataIC50: 10nMAssay Description:Inhibition of the release of Alpha-amylase from rat pancreatic acinar cells.More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetPancreatic alpha-amylase(Rat)
Institute of Research

Curated by ChEMBL
LigandPNGBDBM50005684(CHEMBL284137 | 2-Cyclohexyl-2-phenyl-propionic aci...)
Affinity DataIC50: 21nMAssay Description:Inhibition of the release of Alpha-amylase from rat pancreatic acinar cells.More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetPancreatic alpha-amylase(Rat)
Institute of Research

Curated by ChEMBL
LigandPNGBDBM50005685(Aprophen | 2-(diethylamino)ethyl 2,2-diphenylpropa...)
Affinity DataIC50: 46nMAssay Description:Inhibition of the release of Alpha-amylase from rat pancreatic acinar cells.More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetPancreatic alpha-amylase(Rat)
Institute of Research

Curated by ChEMBL
LigandPNGBDBM50005686(CHEMBL443780 | 2-Cyclohexyl-2-phenyl-propionic aci...)
Affinity DataIC50: 52nMAssay Description:Inhibition of the release of Alpha-amylase from rat pancreatic acinar cells.More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetPancreatic alpha-amylase(Rat)
Institute of Research

Curated by ChEMBL
LigandPNGBDBM50005682(CHEMBL285440 | 2-Cyclohexyl-2-phenyl-propionic aci...)
Affinity DataIC50: 190nMAssay Description:Inhibition of the release of Alpha-amylase from rat pancreatic acinar cells.More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetPancreatic alpha-amylase(Rat)
Institute of Research

Curated by ChEMBL
LigandPNGBDBM50005683(CHEMBL285898 | 2-Cyclohexyl-2-phenyl-propionic aci...)
Affinity DataIC50: 380nMAssay Description:Inhibition of the release of Alpha-amylase from rat pancreatic acinar cells.More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetPancreatic alpha-amylase(Rat)
Institute of Research

Curated by ChEMBL
LigandPNGBDBM50005680(CHEMBL24369 | 2-Cyclohexyl-2-phenyl-propionic acid...)
Affinity DataIC50: 2.70E+3nMAssay Description:Inhibition of the release of Alpha-amylase from rat pancreatic acinar cells.More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetMuscarinic acetylcholine receptor M4(Human)
Institute of Research

Curated by ChEMBL
LigandPNGBDBM50005681(CHEMBL286008 | 2-Cyclohexyl-2-phenyl-propionic aci...)
Affinity DataKi:  1.5nMAssay Description:Antimuscarinic potency and subset specificity was characterised by its inhibition of the [3H]NMS Binding to Muscarinic acetylcholine receptor M4 subt...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetMuscarinic acetylcholine receptor M3(Human)
Institute of Research

Curated by ChEMBL
LigandPNGBDBM50005681(CHEMBL286008 | 2-Cyclohexyl-2-phenyl-propionic aci...)
Affinity DataKi:  1.70nMAssay Description:Antimuscarinic potency and subset specificity was characterised by its inhibition of the [3H]NMS Binding to Muscarinic acetylcholine receptor M3 subt...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetMuscarinic acetylcholine receptor M1(Human)
Institute of Research

Curated by ChEMBL
LigandPNGBDBM50005681(CHEMBL286008 | 2-Cyclohexyl-2-phenyl-propionic aci...)
Affinity DataKi:  1.90nMAssay Description:Antimuscarinic potency and subset specificity was characterised by inhibition of the [3H]NMS Binding to Muscarinic acetylcholine receptor M1 subtypeMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetMuscarinic acetylcholine receptor M1(Human)
Institute of Research

Curated by ChEMBL
LigandPNGBDBM50005685(Aprophen | 2-(diethylamino)ethyl 2,2-diphenylpropa...)
Affinity DataKi:  2.10nMAssay Description:Antimuscarinic potency and subset specificity was characterised by inhibition of the [3H]NMS Binding to Muscarinic acetylcholine receptor M1 subtypeMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetMuscarinic acetylcholine receptor M1(Human)
Institute of Research

Curated by ChEMBL
LigandPNGBDBM50005684(CHEMBL284137 | 2-Cyclohexyl-2-phenyl-propionic aci...)
Affinity DataKi:  2.90nMAssay Description:Antimuscarinic potency and subset specificity was characterised by inhibition of the [3H]NMS Binding to Muscarinic acetylcholine receptor M1 subtypeMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetMuscarinic acetylcholine receptor M3(Human)
Institute of Research

Curated by ChEMBL
LigandPNGBDBM50005684(CHEMBL284137 | 2-Cyclohexyl-2-phenyl-propionic aci...)
Affinity DataKi:  4nMAssay Description:Antimuscarinic potency and subset specificity was characterised by its inhibition of the [3H]NMS Binding to Muscarinic acetylcholine receptor M3 subt...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetMuscarinic acetylcholine receptor M1(Human)
Institute of Research

Curated by ChEMBL
LigandPNGBDBM50005686(CHEMBL443780 | 2-Cyclohexyl-2-phenyl-propionic aci...)
Affinity DataKi:  4nMAssay Description:Antimuscarinic potency and subset specificity was characterised by inhibition of the [3H]NMS Binding to Muscarinic acetylcholine receptor M1 subtypeMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetMuscarinic acetylcholine receptor M4(Human)
Institute of Research

Curated by ChEMBL
LigandPNGBDBM50005684(CHEMBL284137 | 2-Cyclohexyl-2-phenyl-propionic aci...)
Affinity DataKi:  4.60nMAssay Description:Antimuscarinic potency and subset specificity was characterised by its inhibition of the [3H]NMS Binding to Muscarinic acetylcholine receptor M4 subt...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetMuscarinic acetylcholine receptor M4(Human)
Institute of Research

Curated by ChEMBL
LigandPNGBDBM50005685(Aprophen | 2-(diethylamino)ethyl 2,2-diphenylpropa...)
Affinity DataKi:  7.40nMAssay Description:Antimuscarinic potency and subset specificity was characterised by its inhibition of the [3H]NMS Binding to Muscarinic acetylcholine receptor M4 subt...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetMuscarinic acetylcholine receptor M3(Human)
Institute of Research

Curated by ChEMBL
LigandPNGBDBM50005685(Aprophen | 2-(diethylamino)ethyl 2,2-diphenylpropa...)
Affinity DataKi:  7.70nMAssay Description:Antimuscarinic potency and subset specificity was characterised by inhibition of the [3H]NMS Binding to Muscarinic acetylcholine receptor M3 subtypeMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetMuscarinic acetylcholine receptor M2(Human)
Institute of Research

Curated by ChEMBL
LigandPNGBDBM50005685(Aprophen | 2-(diethylamino)ethyl 2,2-diphenylpropa...)
Affinity DataKi:  9.30nMAssay Description:Antimuscarinic potency and subset specificity was characterised by inhibition of the [3H]NMS Binding to Muscarinic acetylcholine receptor M2 subtypeMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetMuscarinic acetylcholine receptor M3(Human)
Institute of Research

Curated by ChEMBL
LigandPNGBDBM50005686(CHEMBL443780 | 2-Cyclohexyl-2-phenyl-propionic aci...)
Affinity DataKi:  9.90nMAssay Description:Antimuscarinic potency and subset specificity was characterised by its inhibition of the [3H]NMS Muscarinic acetylcholine receptor M3 subtypeMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetMuscarinic acetylcholine receptor M4(Human)
Institute of Research

Curated by ChEMBL
LigandPNGBDBM50005686(CHEMBL443780 | 2-Cyclohexyl-2-phenyl-propionic aci...)
Affinity DataKi:  19nMAssay Description:Antimuscarinic potency and subset specificity was characterised by its inhibition of the [3H]NMS Binding to Muscarinic acetylcholine receptor M4 subt...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetMuscarinic acetylcholine receptor M2(Human)
Institute of Research

Curated by ChEMBL
LigandPNGBDBM50005684(CHEMBL284137 | 2-Cyclohexyl-2-phenyl-propionic aci...)
Affinity DataKi:  20nMAssay Description:Antimuscarinic potency and subset specificity was characterised by its inhibition of the [3H]NMS Binding to Muscarinic acetylcholine receptor M2 subt...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetMuscarinic acetylcholine receptor M2(Human)
Institute of Research

Curated by ChEMBL
LigandPNGBDBM50005686(CHEMBL443780 | 2-Cyclohexyl-2-phenyl-propionic aci...)
Affinity DataKi:  23nMAssay Description:Antimuscarinic potency and subset specificity was characterised by its inhibition of the [3H]NMS Binding to Muscarinic acetylcholine receptor M2 subt...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetMuscarinic acetylcholine receptor M2(Human)
Institute of Research

Curated by ChEMBL
LigandPNGBDBM50005681(CHEMBL286008 | 2-Cyclohexyl-2-phenyl-propionic aci...)
Affinity DataKi:  27nMAssay Description:Antimuscarinic potency and subset specificity was characterised by its inhibition of the [3H]NMS Binding to Muscarinic acetylcholine receptor M2 subt...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetMuscarinic acetylcholine receptor M3(Human)
Institute of Research

Curated by ChEMBL
LigandPNGBDBM50005682(CHEMBL285440 | 2-Cyclohexyl-2-phenyl-propionic aci...)
Affinity DataKi:  31nMAssay Description:Antimuscarinic potency and subset specificity was characterised by its inhibition of the [3H]NMS Binding to Muscarinic acetylcholine receptor M3 subt...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetMuscarinic acetylcholine receptor M1(Human)
Institute of Research

Curated by ChEMBL
LigandPNGBDBM50005682(CHEMBL285440 | 2-Cyclohexyl-2-phenyl-propionic aci...)
Affinity DataKi:  41nMAssay Description:Antimuscarinic potency and subset specificity was characterised by inhibition of the [3H]NMS Binding to Muscarinic acetylcholine receptor M1 subtypeMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetMuscarinic acetylcholine receptor M4(Human)
Institute of Research

Curated by ChEMBL
LigandPNGBDBM50005682(CHEMBL285440 | 2-Cyclohexyl-2-phenyl-propionic aci...)
Affinity DataKi:  66nMAssay Description:Antimuscarinic potency and subset specificity was characterised by its inhibition of the [3H]NMS Binding to Muscarinic acetylcholine receptor M4 subt...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetMuscarinic acetylcholine receptor M1(Human)
Institute of Research

Curated by ChEMBL
LigandPNGBDBM50005683(CHEMBL285898 | 2-Cyclohexyl-2-phenyl-propionic aci...)
Affinity DataKi:  111nMAssay Description:Antimuscarinic potency and subset specificity was characterised by inhibition of the [3H]NMS Binding to Muscarinic acetylcholine receptor M1 subtypeMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetMuscarinic acetylcholine receptor M3(Human)
Institute of Research

Curated by ChEMBL
LigandPNGBDBM50005683(CHEMBL285898 | 2-Cyclohexyl-2-phenyl-propionic aci...)
Affinity DataKi:  160nMAssay Description:Antimuscarinic potency and subset specificity was characterised by its inhibition of the [3H]NMS Binding to Muscarinic acetylcholine receptor M3 subt...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetMuscarinic acetylcholine receptor M4(Human)
Institute of Research

Curated by ChEMBL
LigandPNGBDBM50005680(CHEMBL24369 | 2-Cyclohexyl-2-phenyl-propionic acid...)
Affinity DataKi:  173nMAssay Description:Antimuscarinic potency and subset specificity was characterised by its inhibition of the [3H]NMS Binding to Muscarinic acetylcholine receptor M4 subt...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetMuscarinic acetylcholine receptor M3(Human)
Institute of Research

Curated by ChEMBL
LigandPNGBDBM50005680(CHEMBL24369 | 2-Cyclohexyl-2-phenyl-propionic acid...)
Affinity DataKi:  178nMAssay Description:Antimuscarinic potency and subset specificity was characterised by its inhibition of the [3H]NMS Binding to Muscarinic acetylcholine receptor M3 subt...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetMuscarinic acetylcholine receptor M4(Human)
Institute of Research

Curated by ChEMBL
LigandPNGBDBM50005683(CHEMBL285898 | 2-Cyclohexyl-2-phenyl-propionic aci...)
Affinity DataKi:  209nMAssay Description:Antimuscarinic potency and subset specificity was characterised by its inhibition of the [3H]NMS Binding to Muscarinic acetylcholine receptor M4 subt...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetMuscarinic acetylcholine receptor M2(Human)
Institute of Research

Curated by ChEMBL
LigandPNGBDBM50005680(CHEMBL24369 | 2-Cyclohexyl-2-phenyl-propionic acid...)
Affinity DataKi:  246nMAssay Description:Antimuscarinic potency and subset specificity was characterised by its inhibition of the [3H]NMS Binding to Muscarinic acetylcholine receptor M2 subt...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetMuscarinic acetylcholine receptor M2(Human)
Institute of Research

Curated by ChEMBL
LigandPNGBDBM50005683(CHEMBL285898 | 2-Cyclohexyl-2-phenyl-propionic aci...)
Affinity DataKi:  248nMAssay Description:Antimuscarinic potency and subset specificity was characterised by its inhibition of the [3H]NMS Binding to Muscarinic acetylcholine receptor M2 subt...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetMuscarinic acetylcholine receptor M2(Human)
Institute of Research

Curated by ChEMBL
LigandPNGBDBM50005682(CHEMBL285440 | 2-Cyclohexyl-2-phenyl-propionic aci...)
Affinity DataKi:  258nMAssay Description:Antimuscarinic potency and subset specificity was characterised by its inhibition of the [3H]NMS Binding to Muscarinic acetylcholine receptor M2 subt...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetMuscarinic acetylcholine receptor M1(Human)
Institute of Research

Curated by ChEMBL
LigandPNGBDBM50005680(CHEMBL24369 | 2-Cyclohexyl-2-phenyl-propionic acid...)
Affinity DataKi:  298nMAssay Description:Antimuscarinic potency and subset specificity was characterised by inhibition of the [3H]NMS Binding to Muscarinic acetylcholine receptor M1 subtypeMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed