Compile Data Set for Download or QSAR
Report error Found 15 Enz. Inhib. hit(s) with all data for entry = 1549
TargetGag-Pol polyprotein [588-1027]/[588-1147](Human immunodeficiency virus type 1)
University of Oxford

LigandPNGBDBM12080(6-chloro-4-(cyclohexylsulfanyl)-3-propyl-1,2-dihyd...)
Affinity DataIC50: 240nMpH: 7.8 T: 2°CAssay Description:The IC50 of reverse transcriptase is the concentration that inhibits 50% of recombinant HIV-1 RT RNA-directed DNA polymerase activity in vitro.More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/24/2006
Entry Details Article
PubMedPDB3D3D Structure (crystal)
TargetGag-Pol polyprotein [588-1027]/[588-1147](Human immunodeficiency virus type 1)
University of Oxford

LigandPNGBDBM1434(BI-RG-587 | 2-cyclopropyl-7-methyl-2,4,9,15-tetraa...)
Affinity DataIC50: 300nMpH: 7.8 T: 2°CAssay Description:The IC50 of reverse transcriptase is the concentration that inhibits 50% of recombinant HIV-1 RT RNA-directed DNA polymerase activity in vitro.More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/24/2006
Entry Details Article
PubMed
TargetGag-Pol polyprotein [588-1027]/[588-1147](Human immunodeficiency virus type 1)
University of Oxford

LigandPNGBDBM12081(6-chloro-4-(cyclohexanesulfinyl)-3-propyl-1,2-dihy...)
Affinity DataIC50: 380nMpH: 7.8 T: 2°CAssay Description:The IC50 of reverse transcriptase is the concentration that inhibits 50% of recombinant HIV-1 RT RNA-directed DNA polymerase activity in vitro.More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/24/2006
Entry Details Article
PubMed
TargetGag-Pol polyprotein [588-1027]/[588-1147](Human immunodeficiency virus type 1)
University of Oxford

LigandPNGBDBM12079(6-chloro-4-(cyclohexyloxy)-3-(propan-2-yl)-1,2-dih...)
Affinity DataIC50: 630nMpH: 7.8 T: 2°CAssay Description:The IC50 of reverse transcriptase is the concentration that inhibits 50% of recombinant HIV-1 RT RNA-directed DNA polymerase activity in vitro.More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/24/2006
Entry Details Article
PubMedPDB3D3D Structure (crystal)
TargetGag-Pol polyprotein [588-1027]/[588-1147](Human immunodeficiency virus type 1)
University of Oxford

LigandPNGBDBM12078(6-chloro-4-(cyclohexyloxy)-3-propyl-1,2-dihydroqui...)
Affinity DataIC50: 710nMpH: 7.8 T: 2°CAssay Description:The IC50 of reverse transcriptase is the concentration that inhibits 50% of recombinant HIV-1 RT RNA-directed DNA polymerase activity in vitro.More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/24/2006
Entry Details Article
PubMedPDB3D3D Structure (crystal)
TargetGag-Pol polyprotein [588-1127,Y768C]/[588-1147,Y768C](Human immunodeficiency virus type 1)
University of Oxford

LigandPNGBDBM12080(6-chloro-4-(cyclohexylsulfanyl)-3-propyl-1,2-dihyd...)
Affinity DataIC50: 860nMpH: 7.8 T: 2°CAssay Description:The IC50 of reverse transcriptase is the concentration that inhibits 50% of recombinant HIV-1 RT RNA-directed DNA polymerase activity in vitro.More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/24/2006
Entry Details Article
PubMedPDB3D3D Structure (crystal)
TargetGag-Pol polyprotein [588-1127,Y768C]/[588-1147,Y768C](Human immunodeficiency virus type 1)
University of Oxford

LigandPNGBDBM12078(6-chloro-4-(cyclohexyloxy)-3-propyl-1,2-dihydroqui...)
Affinity DataIC50: 1.13E+3nMpH: 7.8 T: 2°CAssay Description:The IC50 of reverse transcriptase is the concentration that inhibits 50% of recombinant HIV-1 RT RNA-directed DNA polymerase activity in vitro.More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/24/2006
Entry Details Article
PubMedPDB3D3D Structure (crystal)
TargetGag-Pol polyprotein [588-1127,Y768C]/[588-1147,Y768C](Human immunodeficiency virus type 1)
University of Oxford

LigandPNGBDBM12081(6-chloro-4-(cyclohexanesulfinyl)-3-propyl-1,2-dihy...)
Affinity DataIC50: 1.26E+3nMpH: 7.8 T: 2°CAssay Description:The IC50 of reverse transcriptase is the concentration that inhibits 50% of recombinant HIV-1 RT RNA-directed DNA polymerase activity in vitro.More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/24/2006
Entry Details Article
PubMed
TargetGag-Pol polyprotein [588-1127,L687I]/[588-1147,L687I](Human immunodeficiency virus type 1)
University of Oxford

LigandPNGBDBM12078(6-chloro-4-(cyclohexyloxy)-3-propyl-1,2-dihydroqui...)
Affinity DataIC50: 1.36E+3nMpH: 7.8 T: 2°CAssay Description:The IC50 of reverse transcriptase is the concentration that inhibits 50% of recombinant HIV-1 RT RNA-directed DNA polymerase activity in vitro.More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/24/2006
Entry Details Article
PubMedPDB3D3D Structure (crystal)
TargetGag-Pol polyprotein [588-1127,L687I]/[588-1147,L687I](Human immunodeficiency virus type 1)
University of Oxford

LigandPNGBDBM12080(6-chloro-4-(cyclohexylsulfanyl)-3-propyl-1,2-dihyd...)
Affinity DataIC50: 1.61E+3nMpH: 7.8 T: 2°CAssay Description:The IC50 of reverse transcriptase is the concentration that inhibits 50% of recombinant HIV-1 RT RNA-directed DNA polymerase activity in vitro.More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/24/2006
Entry Details Article
PubMedPDB3D3D Structure (crystal)
TargetGag-Pol polyprotein [588-1127,L687I]/[588-1147,L687I](Human immunodeficiency virus type 1)
University of Oxford

LigandPNGBDBM12079(6-chloro-4-(cyclohexyloxy)-3-(propan-2-yl)-1,2-dih...)
Affinity DataIC50: 1.96E+3nMpH: 7.8 T: 2°CAssay Description:The IC50 of reverse transcriptase is the concentration that inhibits 50% of recombinant HIV-1 RT RNA-directed DNA polymerase activity in vitro.More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/24/2006
Entry Details Article
PubMedPDB3D3D Structure (crystal)
TargetGag-Pol polyprotein [588-1127,L687I]/[588-1147,L687I](Human immunodeficiency virus type 1)
University of Oxford

LigandPNGBDBM12081(6-chloro-4-(cyclohexanesulfinyl)-3-propyl-1,2-dihy...)
Affinity DataIC50: 2.38E+3nMpH: 7.8 T: 2°CAssay Description:The IC50 of reverse transcriptase is the concentration that inhibits 50% of recombinant HIV-1 RT RNA-directed DNA polymerase activity in vitro.More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/24/2006
Entry Details Article
PubMed
TargetGag-Pol polyprotein [588-1127,Y768C]/[588-1147,Y768C](Human immunodeficiency virus type 1)
University of Oxford

LigandPNGBDBM12079(6-chloro-4-(cyclohexyloxy)-3-(propan-2-yl)-1,2-dih...)
Affinity DataIC50: 2.50E+3nMpH: 7.8 T: 2°CAssay Description:The IC50 of reverse transcriptase is the concentration that inhibits 50% of recombinant HIV-1 RT RNA-directed DNA polymerase activity in vitro.More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/24/2006
Entry Details Article
PubMedPDB3D3D Structure (crystal)
TargetGag-Pol polyprotein [588-1127,Y768C]/[588-1147,Y768C](Human immunodeficiency virus type 1)
University of Oxford

LigandPNGBDBM1434(BI-RG-587 | 2-cyclopropyl-7-methyl-2,4,9,15-tetraa...)
Affinity DataIC50: 1.00E+5nMpH: 7.8 T: 2°CAssay Description:The IC50 of reverse transcriptase is the concentration that inhibits 50% of recombinant HIV-1 RT RNA-directed DNA polymerase activity in vitro.More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/24/2006
Entry Details Article
PubMed
TargetGag-Pol polyprotein [588-1127,L687I]/[588-1147,L687I](Human immunodeficiency virus type 1)
University of Oxford

LigandPNGBDBM1434(BI-RG-587 | 2-cyclopropyl-7-methyl-2,4,9,15-tetraa...)
Affinity DataIC50: 1.00E+5nMpH: 7.8 T: 2°CAssay Description:The IC50 of reverse transcriptase is the concentration that inhibits 50% of recombinant HIV-1 RT RNA-directed DNA polymerase activity in vitro.More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/24/2006
Entry Details Article
PubMed