Compile Data Set for Download or QSAR
Report error Found 6 Enz. Inhib. hit(s) with all data for entry = 50015411
TargetDimer of Protein farnesyltransferase subunit beta(Human)
Schering-Plough Research Institute

Curated by ChEMBL
LigandPNGBDBM50155778(1-[4-((S)-3,10-Dibromo-8-chloro-11H-benzo[5,6]cycl...)
Affinity DataIC50: 0.320nMAssay Description:Inhibition of [3H]FPP incorporation into H-ras CVLS by FarnesyltransferaseMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetDimer of Protein farnesyltransferase subunit beta(Human)
Schering-Plough Research Institute

Curated by ChEMBL
LigandPNGBDBM50155775(4-{2-[4-((S)-3,10-Dibromo-8-chloro-11H-benzo[5,6]c...)
Affinity DataIC50: 0.400nMAssay Description:Inhibition of [3H]FPP incorporation into H-ras CVLS by FarnesyltransferaseMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetDimer of Protein farnesyltransferase subunit beta(Human)
Schering-Plough Research Institute

Curated by ChEMBL
LigandPNGBDBM14459((+)-4-[2-[4-(8-Chloro-3,10-dibromo-6,11-dihydro-5H...)
Affinity DataIC50: 2nMAssay Description:Inhibition of [3H]FPP incorporation into H-ras CVLS by FarnesyltransferaseMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetDimer of Protein farnesyltransferase subunit beta(Human)
Schering-Plough Research Institute

Curated by ChEMBL
LigandPNGBDBM50155776((S)-3,10-Dibromo-8-chloro-11-(1-methanesulfonyl-pi...)
Affinity DataIC50: 3.30nMAssay Description:Inhibition of [3H]FPP incorporation into H-ras CVLS by FarnesyltransferaseMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetDimer of Protein farnesyltransferase subunit beta(Human)
Schering-Plough Research Institute

Curated by ChEMBL
LigandPNGBDBM50155777(4-{2-[4-((R)-3,10-Dibromo-8-chloro-11H-benzo[5,6]c...)
Affinity DataIC50: 16nMAssay Description:Inhibition of [3H]FPP incorporation into H-ras CVLS by FarnesyltransferaseMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetDimer of Protein farnesyltransferase subunit beta(Human)
Schering-Plough Research Institute

Curated by ChEMBL
LigandPNGBDBM14459((+)-4-[2-[4-(8-Chloro-3,10-dibromo-6,11-dihydro-5H...)
Affinity DataIC50: 5.00E+5nMAssay Description:Inhibition of K-Ras transformed NIH3T3 cell proliferationMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed