Compile Data Set for Download or QSAR
Report error Found 23 Enz. Inhib. hit(s) with all data for entry = 50015406
TargetMetabotropic glutamate receptor 2(Human)
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50153757(1-(2-Hydroxy-3-propyl-4-{4-[4-(1H-tetrazol-5-yl)-p...)
Affinity DataEC50:  348nMAssay Description:Binding affinity towards human metabotropic glutamate receptor 2 determined by [35S]GTP gamma S binding assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetMetabotropic glutamate receptor 2(Human)
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50155710(1-{3-Bromo-2-hydroxy-4-[4-(pyridin-3-yloxy)-butoxy...)
Affinity DataEC50:  575nMAssay Description:Binding affinity towards human metabotropic glutamate receptor 2 determined by [35S]GTP gamma S binding assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetMetabotropic glutamate receptor 2(Human)
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50155713(1-{2-Hydroxy-3-methyl-4-[4-(pyridin-2-ylsulfanyl)-...)
Affinity DataEC50:  1.53E+3nMAssay Description:Binding affinity towards human metabotropic glutamate receptor 2 determined by [35S]GTP gamma S binding assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetMetabotropic glutamate receptor 2(Human)
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50155711(1-{2-Hydroxy-3-methyl-4-[4-(pyridin-4-ylsulfanyl)-...)
Affinity DataEC50:  1.06E+3nMAssay Description:Binding affinity towards human metabotropic glutamate receptor 2 determined by [35S]GTP gamma S binding assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetMetabotropic glutamate receptor 2(Human)
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50155708(1-{4-[4-(2-Fluoro-phenoxy)-butoxy]-2-hydroxy-3-met...)
Affinity DataEC50:  1.99E+3nMAssay Description:Binding affinity towards human metabotropic glutamate receptor 2 determined by [35S]GTP gamma S binding assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetMetabotropic glutamate receptor 2(Human)
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50155712(1-{2-Hydroxy-3-methyl-4-[4-(pyridin-3-ylsulfanyl)-...)
Affinity DataEC50:  1.09E+3nMAssay Description:Binding affinity towards human metabotropic glutamate receptor 2 determined by [35S]GTP gamma S binding assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetMetabotropic glutamate receptor 2(Human)
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50155709(1-{2-Hydroxy-3-methyl-4-[4-(pyridin-4-ylsulfanylme...)
Affinity DataEC50:  770nMAssay Description:Binding affinity towards human metabotropic glutamate receptor 2 determined by [35S]GTP gamma S binding assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetMetabotropic glutamate receptor 2(Human)
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50153752(1-(2-Hydroxy-3-methyl-4-{4-[4-(2H-tetrazol-5-yl)-p...)
Affinity DataEC50:  229nMAssay Description:Binding affinity towards human metabotropic glutamate receptor 2 determined by [35S]GTP gamma S binding assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetMetabotropic glutamate receptor 2(Human)
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50155707(1-{2-Hydroxy-3-methyl-4-[4-(4-[1,2,4]triazol-1-yl-...)
Affinity DataEC50:  4.24E+3nMAssay Description:Binding affinity towards human metabotropic glutamate receptor 2 determined by [35S]GTP gamma S binding assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetMetabotropic glutamate receptor 2(Human)
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50155706(1-{4-[4-(2,3-Difluoro-phenoxy)-butoxy]-2-hydroxy-3...)
Affinity DataEC50:  384nMAssay Description:Binding affinity towards human metabotropic glutamate receptor 2 determined by [35S]GTP gamma S binding assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetMetabotropic glutamate receptor 2(Human)
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50155705(1-[2-Hydroxy-3-methyl-4-(4-phenoxy-butoxy)-phenyl]...)
Affinity DataEC50:  4.55E+3nMAssay Description:Binding affinity towards human metabotropic glutamate receptor 2 determined by [35S]GTP gamma S binding assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetMetabotropic glutamate receptor 2(Human)
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50155704(1-{2-Hydroxy-3-methyl-4-[4-(pyridin-4-yloxy)-butox...)
Affinity DataEC50:  3.86E+3nMAssay Description:Binding affinity towards human metabotropic glutamate receptor 2 determined by [35S]GTP gamma S binding assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetMetabotropic glutamate receptor 2(Human)
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50155694(1-{2-Hydroxy-3-methyl-4-[3-(pyridin-4-ylsulfanylme...)
Affinity DataEC50:  819nMAssay Description:Binding affinity towards human metabotropic glutamate receptor 2 determined by [35S]GTP gamma S binding assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetMetabotropic glutamate receptor 2(Human)
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50155703(1-{2-Hydroxy-3-methyl-4-[3-(pyridin-4-ylsulfanyl)-...)
Affinity DataEC50:  890nMAssay Description:Binding affinity towards human metabotropic glutamate receptor 2 determined by [35S]GTP gamma S binding assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetMetabotropic glutamate receptor 2(Human)
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50130608(2,2,2-Trifluoro-ethanesulfonic acid [4-(2-methoxy-...)
Affinity DataEC50:  1.70E+3nMAssay Description:Binding affinity towards human metabotropic glutamate receptor 2 determined by [35S]GTP gamma S binding assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetMetabotropic glutamate receptor 2(Human)
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50155702(1-{2-Hydroxy-3-methyl-4-[4-(pyridin-2-yloxy)-butox...)
Affinity DataEC50:  3.27E+3nMAssay Description:Binding affinity towards human metabotropic glutamate receptor 2 determined by [35S]GTP gamma S binding assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetMetabotropic glutamate receptor 2(Human)
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50155700(1-{2-Hydroxy-3-methyl-4-[4-(pyridin-3-yloxy)-butox...)
Affinity DataEC50:  1.72E+3nMAssay Description:Binding affinity towards human metabotropic glutamate receptor 2 determined by [35S]GTP gamma S binding assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetMetabotropic glutamate receptor 2(Human)
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50155701(1-{2-Hydroxy-3-methyl-4-[4-(pyridin-4-ylsulfanyl)-...)
Affinity DataEC50:  340nMAssay Description:Binding affinity towards human metabotropic glutamate receptor 2 determined by [35S]GTP gamma S binding assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetMetabotropic glutamate receptor 2(Human)
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50155699(1-{3-Bromo-4-[4-(2,3-difluoro-phenoxy)-butoxy]-2-h...)
Affinity DataEC50:  558nMAssay Description:Binding affinity towards human metabotropic glutamate receptor 2 determined by [35S]GTP gamma S binding assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetMetabotropic glutamate receptor 2(Human)
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50155698(1-{3-Bromo-2-hydroxy-4-[4-(pyridin-4-ylsulfanyl)-b...)
Affinity DataEC50:  676nMAssay Description:Binding affinity towards human metabotropic glutamate receptor 2 determined by [35S]GTP gamma S binding assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetMetabotropic glutamate receptor 2(Human)
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50155697(1-[3-Bromo-2-hydroxy-4-(4-phenoxy-butoxy)-phenyl]-...)
Affinity DataEC50:  1.50E+3nMAssay Description:Binding affinity towards human metabotropic glutamate receptor 2 determined by [35S]GTP gamma S binding assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetMetabotropic glutamate receptor 2(Human)
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50155696(1-{2-Hydroxy-3-methyl-4-[4-(pyridin-4-ylsulfanyl)-...)
Affinity DataEC50:  578nMAssay Description:Binding affinity towards human metabotropic glutamate receptor 2 determined by [35S]GTP gamma S binding assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetMetabotropic glutamate receptor 2(Human)
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50155695(1-{2-Hydroxy-3-methyl-4-[2-(pyridin-4-ylsulfanyl)-...)
Affinity DataEC50:  677nMAssay Description:Binding affinity towards human metabotropic glutamate receptor 2 determined by [35S]GTP gamma S binding assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed