Compile Data Set for Download or QSAR
Report error Found 10 Enz. Inhib. hit(s) with all data for entry = 50037365
TargetIntegrin alpha-IIb/beta-3(Human)
A.V. Bogatsky Physico-Chemical Institute of The National Academy of Sciences of Ukraine

Curated by ChEMBL
LigandPNGBDBM50155250(3-[3-(2,3-Dihydro-1H-isoindol-5-ylcarbamoyl)-propi...)
Affinity DataIC50: 8.30nMAssay Description:In vitro inhibition of FITC-labeled fibrinogen binding to alphaIIb-beta3 receptor of human plateletsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/1/2012
Entry Details Article
PubMed
TargetIntegrin alpha-IIb/beta-3(Human)
A.V. Bogatsky Physico-Chemical Institute of The National Academy of Sciences of Ukraine

Curated by ChEMBL
LigandPNGBDBM50155251(3-[3-(2,3-Dihydro-1H-isoindol-5-ylcarbamoyl)-propi...)
Affinity DataIC50: 10nMAssay Description:In vitro inhibition of FITC-labeled fibrinogen binding to alphaIIb-beta3 receptor of human plateletsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/1/2012
Entry Details Article
PubMed
TargetIntegrin alpha-IIb/beta-3(Human)
A.V. Bogatsky Physico-Chemical Institute of The National Academy of Sciences of Ukraine

Curated by ChEMBL
LigandPNGBDBM50155250(3-[3-(2,3-Dihydro-1H-isoindol-5-ylcarbamoyl)-propi...)
Affinity DataIC50: 270nMAssay Description:In vitro inhibition of human platelet aggregation in suspensionMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/1/2012
Entry Details Article
PubMed
TargetIntegrin alpha-IIb/beta-3(Human)
A.V. Bogatsky Physico-Chemical Institute of The National Academy of Sciences of Ukraine

Curated by ChEMBL
LigandPNGBDBM50031552(3-[3-(4-Carbamimidoyl-phenylcarbamoyl)-propionylam...)
Affinity DataIC50: 290nMAssay Description:In vitro inhibition of Collagen-induced platelet aggregation in canine platelet rich plasmaMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/1/2012
Entry Details Article
PubMed
TargetIntegrin alpha-IIb/beta-3(Human)
A.V. Bogatsky Physico-Chemical Institute of The National Academy of Sciences of Ukraine

Curated by ChEMBL
LigandPNGBDBM50155250(3-[3-(2,3-Dihydro-1H-isoindol-5-ylcarbamoyl)-propi...)
Affinity DataIC50: 860nMAssay Description:In vitro inhibition of human platelet aggregation in platelet rich plasmaMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/1/2012
Entry Details Article
PubMed
TargetIntegrin alpha-IIb/beta-3(Human)
A.V. Bogatsky Physico-Chemical Institute of The National Academy of Sciences of Ukraine

Curated by ChEMBL
LigandPNGBDBM50031564(3-[3-(4-Carbamimidoyl-phenylcarbamoyl)-propionylam...)
Affinity DataIC50: 1.09E+3nMAssay Description:In vitro inhibition of Collagen-induced platelet aggregation in canine platelet rich plasmaMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/1/2012
Entry Details Article
PubMed
TargetIntegrin alpha-IIb/beta-3(Human)
A.V. Bogatsky Physico-Chemical Institute of The National Academy of Sciences of Ukraine

Curated by ChEMBL
LigandPNGBDBM50155251(3-[3-(2,3-Dihydro-1H-isoindol-5-ylcarbamoyl)-propi...)
Affinity DataIC50: 2.09E+3nMAssay Description:In vitro inhibition of human platelet aggregation in suspensionMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/1/2012
Entry Details Article
PubMed
TargetIntegrin alpha-IIb/beta-3(Human)
A.V. Bogatsky Physico-Chemical Institute of The National Academy of Sciences of Ukraine

Curated by ChEMBL
LigandPNGBDBM50155251(3-[3-(2,3-Dihydro-1H-isoindol-5-ylcarbamoyl)-propi...)
Affinity DataIC50: 2.75E+3nMAssay Description:In vitro inhibition of human platelet aggregation in platelet rich plasmaMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/1/2012
Entry Details Article
PubMed
TargetIntegrin alpha-IIb/beta-3(Human)
A.V. Bogatsky Physico-Chemical Institute of The National Academy of Sciences of Ukraine

Curated by ChEMBL
LigandPNGBDBM50155250(3-[3-(2,3-Dihydro-1H-isoindol-5-ylcarbamoyl)-propi...)
Affinity DataKi:  4.20nMAssay Description:In vitro binding affinity for FITC-labeled fibrinogen binding to alphaIIb-beta3 receptor of human plateletsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/1/2012
Entry Details Article
PubMed
TargetIntegrin alpha-IIb/beta-3(Human)
A.V. Bogatsky Physico-Chemical Institute of The National Academy of Sciences of Ukraine

Curated by ChEMBL
LigandPNGBDBM50155251(3-[3-(2,3-Dihydro-1H-isoindol-5-ylcarbamoyl)-propi...)
Affinity DataKi:  7.10nMAssay Description:In vitro binding affinity for FITC-labeled fibrinogen binding to alphaIIb-beta3 receptor of human plateletsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/1/2012
Entry Details Article
PubMed