Compile Data Set for Download or QSAR
Report error Found 41 Enz. Inhib. hit(s) with all data for entry = 50037472
TargetCytochrome P450 2D6(Human)
University of Leicester

Curated by ChEMBL
LigandPNGBDBM50013515(yohimbic acid methyl ester | 17alpha-hydroxyyohimb...)
Affinity DataIC50: 8.40nMAssay Description:Inhibitory concentration against cytochrome P450 2D6More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/3/2012
Entry Details Article
PubMed
TargetCytochrome P450 2D6(Human)
University of Leicester

Curated by ChEMBL
LigandPNGBDBM50121975((6-Methoxy-quinolin-4-yl)-(5-vinyl-1-aza-bicyclo[2...)
Affinity DataIC50: 10nMAssay Description:Inhibitory concentration against cytochrome P450 2D6More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/3/2012
Entry Details Article
PubMedPDB3D3D Structure (crystal)
TargetCytochrome P450 2D6(Human)
University of Leicester

Curated by ChEMBL
LigandPNGBDBM50066721(1-{[2-(diethylamino)ethyl]amino}-4-(hydroxymethyl)...)
Affinity DataIC50: 1.50E+3nMAssay Description:Inhibitory concentration against cytochrome P450 2D6More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/3/2012
Entry Details Article
PubMed
TargetCytochrome P450 2D6(Human)
University of Leicester

Curated by ChEMBL
LigandPNGBDBM50154453(NCI-343513 | 1-(4-Fluoro-phenyl)-4-{4-[(4-fluoro-p...)
Affinity DataIC50: 1.60E+3nMAssay Description:Inhibitory concentration against cytochrome P450 2D6More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/3/2012
Entry Details Article
PubMed
TargetCytochrome P450 2D6(Human)
University of Leicester

Curated by ChEMBL
LigandPNGBDBM50370411(GNF-PF-3189 | CINCHORINE)
Affinity DataIC50: 1.80E+3nMAssay Description:Inhibitory concentration against cytochrome P450 2D6More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/3/2012
Entry Details Article
PubMed
TargetCytochrome P450 2D6(Human)
University of Leicester

Curated by ChEMBL
LigandPNGBDBM50154467(NCI-10777 | 1-[3-(2,5-Dichloro-phenylsulfanyl)-pro...)
Affinity DataIC50: 2.10E+3nMAssay Description:Inhibitory concentration against cytochrome P450 2D6More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/3/2012
Entry Details Article
PubMed
TargetCytochrome P450 2D6(Human)
University of Leicester

Curated by ChEMBL
LigandPNGBDBM50154454(NCI-13239 | (3-Aminomethyl-7-chloro-quinolin-4-yl)...)
Affinity DataIC50: 2.20E+3nMAssay Description:Inhibitory concentration against cytochrome P450 2D6More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/3/2012
Entry Details Article
PubMed
TargetCytochrome P450 2D6(Human)
University of Leicester

Curated by ChEMBL
LigandPNGBDBM50154460(3-(9-methoxy-5,11-dimethyl-6H-pyrido[4,3-b]carbazo...)
Affinity DataIC50: 2.40E+3nMAssay Description:Inhibitory concentration against cytochrome P450 2D6More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/3/2012
Entry Details Article
PubMed
TargetCytochrome P450 2D6(Human)
University of Leicester

Curated by ChEMBL
LigandPNGBDBM112777(NORTRIPTYLINE | US8629135, SW-02)
Affinity DataIC50: 2.60E+3nMAssay Description:Inhibitory concentration against cytochrome P450 2D6More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/3/2012
Entry Details Article
PubMed
TargetCytochrome P450 2D6(Human)
University of Leicester

Curated by ChEMBL
LigandPNGBDBM50154461(NCI-303812 | NCI-17383 | 2-[1-(2-Chloro-benzyl)-2-...)
Affinity DataIC50: 3.50E+3nMAssay Description:Inhibitory concentration against cytochrome P450 2D6More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/3/2012
Entry Details Article
PubMed
TargetCytochrome P450 2D6(Human)
University of Leicester

Curated by ChEMBL
LigandPNGBDBM50154461(NCI-303812 | NCI-17383 | 2-[1-(2-Chloro-benzyl)-2-...)
Affinity DataIC50: 3.50E+3nMAssay Description:Inhibitory concentration against cytochrome P450 2D6More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/3/2012
Entry Details Article
PubMed
TargetCytochrome P450 2D6(Human)
University of Leicester

Curated by ChEMBL
LigandPNGBDBM50154459({2-[4-((E)-1,2-Diphenyl-vinyl)-phenoxy]-ethyl}-dim...)
Affinity DataIC50: 7.20E+3nMAssay Description:Inhibitory concentration against cytochrome P450 2D6More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/3/2012
Entry Details Article
PubMed
TargetCytochrome P450 2D6(Human)
University of Leicester

Curated by ChEMBL
LigandPNGBDBM50014779(CHEMBL422093 | 1-[Bis-(4-chloro-phenyl)-methyl]-pi...)
Affinity DataIC50: 7.30E+3nMAssay Description:Inhibitory concentration against cytochrome P450 2D6More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/3/2012
Entry Details Article
PubMed
TargetCytochrome P450 2D6(Human)
University of Leicester

Curated by ChEMBL
LigandPNGBDBM50154452(1-Amino-3-(4-chloro-benzylsulfanyl)-propan-2-ol | ...)
Affinity DataIC50: 8.00E+3nMAssay Description:Inhibitory concentration against cytochrome P450 2D6More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/3/2012
Entry Details Article
PubMed
TargetCytochrome P450 2D6(Human)
University of Leicester

Curated by ChEMBL
LigandPNGBDBM50154468(2-(2-Amino-ethyl)-3-(4-chloro-phenyl)-3-hydroxy-2,...)
Affinity DataIC50: 8.50E+3nMAssay Description:Inhibitory concentration against cytochrome P450 2D6More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/3/2012
Entry Details Article
PubMed
TargetCytochrome P450 2D6(Human)
University of Leicester

Curated by ChEMBL
LigandPNGBDBM50154469(Diethyl-{2-[2-(4-oxo-2-phenyl-4H-chromen-8-yl)-ace...)
Affinity DataIC50: 8.70E+3nMAssay Description:Inhibitory concentration against cytochrome P450 2D6More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/3/2012
Entry Details Article
PubMed
TargetCytochrome P450 2D6(Human)
University of Leicester

Curated by ChEMBL
LigandPNGBDBM87351(m-AMSA | N-[4-(acridin-9-ylamino)-3-methoxyphenyl]...)
Affinity DataIC50: 1.02E+4nMAssay Description:Inhibitory concentration against cytochrome P450 2D6More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/3/2012
Entry Details Article
PubMed
TargetCytochrome P450 2D6(Human)
University of Leicester

Curated by ChEMBL
LigandPNGBDBM87351(m-AMSA | N-[4-(acridin-9-ylamino)-3-methoxyphenyl]...)
Affinity DataIC50: 1.05E+4nMAssay Description:Inhibitory concentration against cytochrome P450 2D6More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/3/2012
Entry Details Article
PubMed
TargetCytochrome P450 2D6(Human)
University of Leicester

Curated by ChEMBL
LigandPNGBDBM50022673(NSC-278214 | Isopropyl-carbamic acid 3-(3,4-dichlo...)
Affinity DataIC50: 1.10E+4nMAssay Description:Inhibitory concentration against cytochrome P450 2D6More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/3/2012
Entry Details Article
PubMed
TargetCytochrome P450 2D6(Human)
University of Leicester

Curated by ChEMBL
LigandPNGBDBM50154462(NCI-305884 | N-Methyl-N-[4-(7-methyl-1H-imidazo[4,...)
Affinity DataIC50: 1.81E+4nMAssay Description:Inhibitory concentration against cytochrome P450 2D6More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/3/2012
Entry Details Article
PubMed
TargetCytochrome P450 2D6(Human)
University of Leicester

Curated by ChEMBL
LigandPNGBDBM50154449(CHEMBL84440 | cid_3449946 | 5-[4-(2-Amino-ethylami...)
Affinity DataIC50: 3.00E+4nMAssay Description:Inhibitory concentration against cytochrome P450 2D6More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/3/2012
Entry Details Article
PubMed
TargetCytochrome P450 2D6(Human)
University of Leicester

Curated by ChEMBL
LigandPNGBDBM50033894(NCI-308847 | 5-Amino-2-(2-dimethylamino-ethyl)-ben...)
Affinity DataIC50: 3.96E+4nMAssay Description:Inhibitory concentration against cytochrome P450 2D6More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/3/2012
Entry Details Article
PubMed
TargetCytochrome P450 2D6(Human)
University of Leicester

Curated by ChEMBL
LigandPNGBDBM50037511(Daniquidone | 8-Amino-10H-isoindolo[1,2-b]quinazol...)
Affinity DataIC50: 4.80E+4nMAssay Description:Inhibitory concentration against cytochrome P450 2D6More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/3/2012
Entry Details Article
PubMed
TargetCytochrome P450 2D6(Human)
University of Leicester

Curated by ChEMBL
LigandPNGBDBM50003677(4-{4-[bis(2-chloroethyl)amino]phenyl}butanoic acid...)
Affinity DataIC50: 6.51E+4nMAssay Description:Inhibitory concentration against cytochrome P450 2D6More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/3/2012
Entry Details Article
PubMed
TargetCytochrome P450 2D6(Human)
University of Leicester

Curated by ChEMBL
LigandPNGBDBM67690(SMR000058480 | DHAD | 1,4-bis[2-(2-hydroxyethylami...)
Affinity DataIC50: 7.63E+4nMAssay Description:Inhibitory concentration against cytochrome P450 2D6More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/3/2012
Entry Details Article
PubMed
TargetCytochrome P450 2D6(Human)
University of Leicester

Curated by ChEMBL
LigandPNGBDBM50154457(3-(6-amino-8a-methoxy-1,5-dimethyl-4,7-dioxo-1,1a,...)
Affinity DataIC50: 9.43E+4nMAssay Description:Inhibitory concentration against cytochrome P450 2D6More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/3/2012
Entry Details Article
PubMed
TargetCytochrome P450 2D6(Human)
University of Leicester

Curated by ChEMBL
LigandPNGBDBM50028411(3-Methoxy-13-methyl-4-nitro-6,7,8,9,11,12,13,14,15...)
Affinity DataIC50: 1.96E+5nMAssay Description:Inhibitory concentration against cytochrome P450 2D6More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/3/2012
Entry Details Article
PubMed
TargetCytochrome P450 2D6(Human)
University of Leicester

Curated by ChEMBL
LigandPNGBDBM50154464(NCI-100857 | 2-Amino-5-(3-amino-propyl)-6-phenyl-p...)
Affinity DataIC50: 2.34E+5nMAssay Description:Inhibitory concentration against cytochrome P450 2D6More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/3/2012
Entry Details Article
PubMed
TargetCytochrome P450 2D6(Human)
University of Leicester

Curated by ChEMBL
LigandPNGBDBM50154466(NCI-193457 | N-[1-Chloro-2-methylamino-eth-(E)-yli...)
Affinity DataIC50: 2.65E+5nMAssay Description:Inhibitory concentration against cytochrome P450 2D6More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/3/2012
Entry Details Article
PubMed
TargetCytochrome P450 2D6(Human)
University of Leicester

Curated by ChEMBL
LigandPNGBDBM50154470((2E)-{[(4-methoxyphenyl)sulfonyl]hydrazono}acetic ...)
Affinity DataIC50: 2.88E+5nMAssay Description:Inhibitory concentration against cytochrome P450 2D6More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/3/2012
Entry Details Article
PubMed
TargetCytochrome P450 2D6(Human)
University of Leicester

Curated by ChEMBL
LigandPNGBDBM50154447(NCI-172112 | 2-(2,3-Dichloro-propyl)-spiro[4.5]dec...)
Affinity DataIC50: 3.10E+5nMAssay Description:Inhibitory concentration against cytochrome P450 2D6More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/3/2012
Entry Details Article
PubMed
TargetCytochrome P450 2D6(Human)
University of Leicester

Curated by ChEMBL
LigandPNGBDBM50370521(BRUCEANTIN)
Affinity DataIC50: 5.14E+5nMAssay Description:Inhibitory concentration against cytochrome P450 2D6More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/3/2012
Entry Details Article
PubMed
TargetCytochrome P450 2D6(Human)
University of Leicester

Curated by ChEMBL
LigandPNGBDBM50154456(Morpholin-4-yl-(4-phenyl-piperidin-4-yl)-methanone...)
Affinity DataIC50: 5.54E+5nMAssay Description:Inhibitory concentration against cytochrome P450 2D6More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/3/2012
Entry Details Article
PubMed
TargetCytochrome P450 2D6(Human)
University of Leicester

Curated by ChEMBL
LigandPNGBDBM50154450(4-(Benzylamino-methyl)-benzoic acid | CHEMBL186292)
Affinity DataIC50: 5.70E+5nMAssay Description:Inhibitory concentration against cytochrome P450 2D6More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/3/2012
Entry Details Article
PubMed
TargetCytochrome P450 2D6(Human)
University of Leicester

Curated by ChEMBL
LigandPNGBDBM50154471(Sulfamic acid 7-sulfamoyloxy-heptyl ester | CHEMBL...)
Affinity DataIC50: 6.99E+5nMAssay Description:Inhibitory concentration against cytochrome P450 2D6More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/3/2012
Entry Details Article
PubMed
TargetCytochrome P450 2D6(Human)
University of Leicester

Curated by ChEMBL
LigandPNGBDBM50154448(NCI-314055 | N,N-Bis-(2-hydroxy-ethyl)-2-(2-nitro-...)
Affinity DataIC50: 1.02E+6nMAssay Description:Inhibitory concentration against cytochrome P450 2D6More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/3/2012
Entry Details Article
PubMed
TargetCytochrome P450 2D6(Human)
University of Leicester

Curated by ChEMBL
LigandPNGBDBM50154463(N-(2-chloroethyl)-N''-(1-formyl-2,3,4,5-tetrahydro...)
Affinity DataIC50: 2.02E+6nMAssay Description:Inhibitory concentration against cytochrome P450 2D6More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/3/2012
Entry Details Article
PubMed
TargetCytochrome P450 2D6(Human)
University of Leicester

Curated by ChEMBL
LigandPNGBDBM50121975((6-Methoxy-quinolin-4-yl)-(5-vinyl-1-aza-bicyclo[2...)
Affinity DataKi:  30nMAssay Description:Binding affinity for cytochrome P450 2D6More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/3/2012
Entry Details Article
PubMedPDB3D3D Structure (crystal)
TargetCytochrome P450 2D6(Human)
University of Leicester

Curated by ChEMBL
LigandPNGBDBM50013515(yohimbic acid methyl ester | 17alpha-hydroxyyohimb...)
Affinity DataKi:  180nMAssay Description:Binding affinity for cytochrome P450 2D6More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/3/2012
Entry Details Article
PubMed
TargetCytochrome P450 2D6(Human)
University of Leicester

Curated by ChEMBL
LigandPNGBDBM87351(m-AMSA | N-[4-(acridin-9-ylamino)-3-methoxyphenyl]...)
Affinity DataKi:  7.50E+3nMAssay Description:Binding affinity for cytochrome P450 2D6More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/3/2012
Entry Details Article
PubMed
TargetCytochrome P450 2D6(Human)
University of Leicester

Curated by ChEMBL
LigandPNGBDBM50370411(GNF-PF-3189 | CINCHORINE)
Affinity DataKi:  2.10E+4nMAssay Description:Binding affinity for cytochrome P450 2D6More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/3/2012
Entry Details Article
PubMed