Compile Data Set for Download or QSAR
Report error Found 29 Enz. Inhib. hit(s) with all data for entry = 50015287
TargetC-C chemokine receptor type 2(Human)
Institute For Bio-Medical Research

Curated by ChEMBL
LigandPNGBDBM50153917(3-{1-Hydroxy-3-[4-(4-methanesulfonyl-benzyl)-[1,4]...)
Affinity DataIC50: 710nMAssay Description:Concentration required to inhibit [125I]MCP-1 (Monocyte Chemoattractant Protein-1) binding to THP-1 cellMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetC-C chemokine receptor type 2(Human)
Institute For Bio-Medical Research

Curated by ChEMBL
LigandPNGBDBM50153910(1,1-di(3-hydroxyphenyl)-3-[4-(4-methylsulfonylbenz...)
Affinity DataIC50: 1.50E+3nMAssay Description:Concentration required to inhibit [125I]MCP-1 (Monocyte Chemoattractant Protein-1) binding to THP-1 cell; not determinedMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetC-C chemokine receptor type 2(Human)
Institute For Bio-Medical Research

Curated by ChEMBL
LigandPNGBDBM50153933(4-{4-[3-Hydroxy-3-(3-hydroxy-phenyl)-3-phenyl-prop...)
Affinity DataIC50: 1.50E+3nMAssay Description:Concentration required to inhibit [125I]MCP-1 (Monocyte Chemoattractant Protein-1) binding to THP-1 cellMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetC-C chemokine receptor type 2(Human)
Institute For Bio-Medical Research

Curated by ChEMBL
LigandPNGBDBM50153927(3-{1-(4-Fluoro-phenyl)-1-hydroxy-3-[4-(4-methanesu...)
Affinity DataIC50: 1.50E+3nMAssay Description:Concentration required to inhibit [125I]MCP-1 (Monocyte Chemoattractant Protein-1) binding to THP-1 cellMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetC-C chemokine receptor type 2(Human)
Institute For Bio-Medical Research

Curated by ChEMBL
LigandPNGBDBM50153922(3-{1-(4-Chloro-phenyl)-1-hydroxy-3-[4-(4-methanesu...)
Affinity DataIC50: 1.50E+3nMAssay Description:Concentration required to inhibit [125I]MCP-1 (Monocyte Chemoattractant Protein-1) binding to THP-1 cellMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetC-C chemokine receptor type 2(Human)
Institute For Bio-Medical Research

Curated by ChEMBL
LigandPNGBDBM50153920(3-{1-(3-Fluoro-phenyl)-1-hydroxy-3-[4-(4-methanesu...)
Affinity DataIC50: 2.40E+3nMAssay Description:Concentration required to inhibit [125I]MCP-1 (Monocyte Chemoattractant Protein-1) binding to THP-1 cellMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetC-C chemokine receptor type 2(Human)
Institute For Bio-Medical Research

Curated by ChEMBL
LigandPNGBDBM50153912(1-(3-Hydroxymethyl-phenyl)-3-[4-(4-methanesulfonyl...)
Affinity DataIC50: 4.00E+3nMAssay Description:Concentration required to inhibit [125I]MCP-1 (Monocyte Chemoattractant Protein-1) binding to THP-1 cellMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetC-C chemokine receptor type 2(Human)
Institute For Bio-Medical Research

Curated by ChEMBL
LigandPNGBDBM50153919(3-[4-(4-Methanesulfonyl-benzyl)-[1,4]diazepan-1-yl...)
Affinity DataIC50: 4.10E+3nMAssay Description:Concentration required to inhibit [125I]MCP-1 (Monocyte Chemoattractant Protein-1) binding to THP-1 cellMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetC-C chemokine receptor type 2(Human)
Institute For Bio-Medical Research

Curated by ChEMBL
LigandPNGBDBM50153925(1-(3-Amino-phenyl)-3-[4-(4-methanesulfonyl-benzyl)...)
Affinity DataIC50: 4.20E+3nMAssay Description:Concentration required to inhibit [125I]MCP-1 (Monocyte Chemoattractant Protein-1) binding to THP-1 cellMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetC-C chemokine receptor type 2(Human)
Institute For Bio-Medical Research

Curated by ChEMBL
LigandPNGBDBM50153934(3-{1-(3-Chloro-phenyl)-1-hydroxy-3-[4-(4-methanesu...)
Affinity DataIC50: 4.50E+3nMAssay Description:Concentration required to inhibit [125I]MCP-1 (Monocyte Chemoattractant Protein-1) binding to THP-1 cellMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetC-C chemokine receptor type 2(Human)
Institute For Bio-Medical Research

Curated by ChEMBL
LigandPNGBDBM50153913(3-[4-(4-Methanesulfonyl-benzyl)-[1,4]diazepan-1-yl...)
Affinity DataIC50: 5.00E+3nMAssay Description:Concentration required to inhibit [125I]MCP-1 (Monocyte Chemoattractant Protein-1) binding to THP-1 cellMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetC-C chemokine receptor type 2(Human)
Institute For Bio-Medical Research

Curated by ChEMBL
LigandPNGBDBM50153937(4-Methyl-thiophene-2-carboxylic acid N''-(2-{4-[3-...)
Affinity DataIC50: 6.40E+3nMAssay Description:Concentration required to inhibit [125I]MCP-1 (Monocyte Chemoattractant Protein-1) binding to THP-1 cellMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetC-C chemokine receptor type 2(Human)
Institute For Bio-Medical Research

Curated by ChEMBL
LigandPNGBDBM50153935(1,1-Bis-(4-fluoro-phenyl)-3-[4-(4-methanesulfonyl-...)
Affinity DataIC50: 7.00E+3nMAssay Description:Concentration required to inhibit [125I]MCP-1 (Monocyte Chemoattractant Protein-1) binding to THP-1 cellMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetC-C chemokine receptor type 2(Human)
Institute For Bio-Medical Research

Curated by ChEMBL
LigandPNGBDBM50153926(4-Methyl-thiophene-2-carboxylic acid N''-{2-[4-(4-...)
Affinity DataIC50: 7.40E+3nMAssay Description:Concentration required to inhibit [125I]MCP-1 (Monocyte Chemoattractant Protein-1) binding to THP-1 cellMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetC-C chemokine receptor type 2(Human)
Institute For Bio-Medical Research

Curated by ChEMBL
LigandPNGBDBM50153936(3-[4-(4-Methanesulfonyl-benzyl)-[1,4]diazepan-1-yl...)
Affinity DataIC50: 7.90E+3nMAssay Description:Concentration required to inhibit [125I]MCP-1 (Monocyte Chemoattractant Protein-1) binding to THP-1 cellMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetC-C chemokine receptor type 2(Human)
Institute For Bio-Medical Research

Curated by ChEMBL
LigandPNGBDBM50153924(3-{1-(3,5-Difluoro-phenyl)-1-hydroxy-3-[4-(4-metha...)
Affinity DataIC50: 9.30E+3nMAssay Description:Concentration required to inhibit [125I]MCP-1 (Monocyte Chemoattractant Protein-1) binding to THP-1 cellMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetC-C chemokine receptor type 2(Human)
Institute For Bio-Medical Research

Curated by ChEMBL
LigandPNGBDBM50153915(1,1-Bis-(4-chloro-phenyl)-3-[4-(4-methanesulfonyl-...)
Affinity DataIC50: 1.10E+4nMAssay Description:Concentration required to inhibit [125I]MCP-1 (Monocyte Chemoattractant Protein-1) binding to THP-1 cellMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetC-C chemokine receptor type 2(Human)
Institute For Bio-Medical Research

Curated by ChEMBL
LigandPNGBDBM50153911(1-(3,3-Diphenyl-propyl)-4-pyridin-4-ylmethyl-[1,4]...)
Affinity DataIC50: 1.10E+4nMAssay Description:Concentration required to inhibit [125I]MCP-1 (Monocyte Chemoattractant Protein-1) binding to THP-1 cellMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetC-C chemokine receptor type 2(Human)
Institute For Bio-Medical Research

Curated by ChEMBL
LigandPNGBDBM50153916(1-(3-Fluoro-phenyl)-3-[4-(4-methanesulfonyl-benzyl...)
Affinity DataIC50: 1.20E+4nMAssay Description:Concentration required to inhibit [125I]MCP-1 (Monocyte Chemoattractant Protein-1) binding to THP-1 cellMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetC-C chemokine receptor type 2(Human)
Institute For Bio-Medical Research

Curated by ChEMBL
LigandPNGBDBM50153931(1-(3,3-Diphenyl-propyl)-4-(4-methanesulfonyl-benzy...)
Affinity DataIC50: 1.30E+4nMAssay Description:Concentration required to inhibit [125I]MCP-1 (Monocyte Chemoattractant Protein-1) binding to THP-1 cellMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetC-C chemokine receptor type 2(Human)
Institute For Bio-Medical Research

Curated by ChEMBL
LigandPNGBDBM50153928(3-[4-(4-Methanesulfonyl-benzyl)-[1,4]diazepan-1-yl...)
Affinity DataIC50: 1.60E+4nMAssay Description:Concentration required to inhibit [125I]MCP-1 (Monocyte Chemoattractant Protein-1) binding to THP-1 cellMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetC-C chemokine receptor type 2(Human)
Institute For Bio-Medical Research

Curated by ChEMBL
LigandPNGBDBM50153930(1-(3,3-Diphenyl-propyl)-4-(4-nitro-benzyl)-[1,4]di...)
Affinity DataIC50: 1.90E+4nMAssay Description:Concentration required to inhibit [125I]MCP-1 (Monocyte Chemoattractant Protein-1) binding to THP-1 cellMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetC-C chemokine receptor type 2(Human)
Institute For Bio-Medical Research

Curated by ChEMBL
LigandPNGBDBM50153923(1,1-di(4-hydroxyphenyl)-3-[4-(4-methylsulfonylbenz...)
Affinity DataIC50: 2.10E+4nMAssay Description:Concentration required to inhibit [125I]MCP-1 (Monocyte Chemoattractant Protein-1) binding to THP-1 cellMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetC-C chemokine receptor type 2(Human)
Institute For Bio-Medical Research

Curated by ChEMBL
LigandPNGBDBM50153918(Thiophene-2-carboxylic acid N''-(2-{4-[3-hydroxy-3...)
Affinity DataIC50: 2.80E+4nMAssay Description:Concentration required to inhibit [125I]MCP-1 (Monocyte Chemoattractant Protein-1) binding to THP-1 cellMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetC-C chemokine receptor type 2(Human)
Institute For Bio-Medical Research

Curated by ChEMBL
LigandPNGBDBM50153932(Thiophene-2-carboxylic acid N''-{2-[4-(4-chloro-be...)
Affinity DataIC50: 3.00E+4nMAssay Description:Concentration required to inhibit [125I]MCP-1 (Monocyte Chemoattractant Protein-1) binding to THP-1 cellMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetC-C chemokine receptor type 2(Human)
Institute For Bio-Medical Research

Curated by ChEMBL
LigandPNGBDBM50153909(1,1-Bis-(3-fluoro-phenyl)-3-[4-(4-methanesulfonyl-...)
Affinity DataIC50: 3.40E+4nMAssay Description:Concentration required to inhibit [125I]MCP-1 (Monocyte Chemoattractant Protein-1) binding to THP-1 cellMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetC-C chemokine receptor type 2(Human)
Institute For Bio-Medical Research

Curated by ChEMBL
LigandPNGBDBM50153921(4-[4-(3,3-Diphenyl-propyl)-[1,4]diazepan-1-ylmethy...)
Affinity DataIC50: 4.30E+4nMAssay Description:Concentration required to inhibit [125I]MCP-1 (Monocyte Chemoattractant Protein-1) binding to THP-1 cellMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetC-C chemokine receptor type 2(Human)
Institute For Bio-Medical Research

Curated by ChEMBL
LigandPNGBDBM50153929(1,1-Bis-(4-dimethylamino-phenyl)-3-[4-(4-methanesu...)
Affinity DataIC50: 4.50E+4nMAssay Description:Concentration required to inhibit [125I]MCP-1 (Monocyte Chemoattractant Protein-1) binding to THP-1 cellMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetC-C chemokine receptor type 2(Human)
Institute For Bio-Medical Research

Curated by ChEMBL
LigandPNGBDBM50153914(1-(4-Chloro-benzyl)-4-(4-methanesulfonyl-benzyl)-[...)
Affinity DataIC50: 1.00E+5nMAssay Description:Concentration required to inhibit [125I]MCP-1 (Monocyte Chemoattractant Protein-1) binding to THP-1 cellMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed