Compile Data Set for Download or QSAR
Report error Found 19 Enz. Inhib. hit(s) with all data for entry = 50015274
TargetMetabotropic glutamate receptor 2(Human)
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50153749(1-(2-Hydroxy-3-methyl-4-{4-[4-(2H-tetrazol-5-yl)-p...)
Affinity DataEC50:  3.37E+3nMAssay Description:Effective concentration for binding to human metabotropic glutamate receptor 2 as determined by GTPgammaS assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetMetabotropic glutamate receptor 2(Human)
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50153757(1-(2-Hydroxy-3-propyl-4-{4-[4-(1H-tetrazol-5-yl)-p...)
Affinity DataEC50:  348nMAssay Description:Effective concentration for binding to human metabotropic glutamate receptor 2 as determined by GTPgammaS assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetMetabotropic glutamate receptor 2(Human)
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50153756(1-(3-Bromo-2-hydroxy-4-{4-[4-(2H-tetrazol-5-yl)-ph...)
Affinity DataEC50:  93nMAssay Description:Effective concentration for binding to human metabotropic glutamate receptor 2 as determined by GTPgammaS assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetMetabotropic glutamate receptor 2(Human)
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50153754(1-(2-Hydroxy-3-propyl-4-{5-[4-(2H-tetrazol-5-yl)-p...)
Affinity DataEC50:  3.31E+3nMAssay Description:Effective concentration for binding to human metabotropic glutamate receptor 2 as determined by GTPgammaS assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetMetabotropic glutamate receptor 2(Human)
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50153755(4-[4-(4-Acetyl-3-hydroxy-2-propyl-phenoxy)-butoxy]...)
Affinity DataEC50:  1.82E+3nMAssay Description:Effective concentration for binding to human metabotropic glutamate receptor 2 as determined by GTPgammaS assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetMetabotropic glutamate receptor 2(Human)
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50153753(1-(2-Hydroxy-4-{1-methyl-4-[4-(2H-tetrazol-5-yl)-p...)
Affinity DataEC50:  241nMAssay Description:Effective concentration for binding to human metabotropic glutamate receptor 2 as determined by GTPgammaS assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetMetabotropic glutamate receptor 2(Human)
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50130608(2,2,2-Trifluoro-ethanesulfonic acid [4-(2-methoxy-...)
Affinity DataEC50:  1.70E+3nMAssay Description:Effective concentration for binding to human metabotropic glutamate receptor 2 as determined by GTPgammaS assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetMetabotropic glutamate receptor 2(Human)
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50153752(1-(2-Hydroxy-3-methyl-4-{4-[4-(2H-tetrazol-5-yl)-p...)
Affinity DataEC50:  229nMAssay Description:Effective concentration for binding to human metabotropic glutamate receptor 2 as determined by GTPgammaS assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetMetabotropic glutamate receptor 2(Human)
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50153751(1-(3-Bromo-2-hydroxy-4-{4-[4-(2H-tetrazol-5-yl)-ph...)
Affinity DataEC50:  878nMAssay Description:Effective concentration for binding to human metabotropic glutamate receptor 2 as determined by GTPgammaS assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetMetabotropic glutamate receptor 2(Human)
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50153750(1-(2-Hydroxy-3-methyl-4-{4-[4-(2H-tetrazol-5-yl)-p...)
Affinity DataEC50:  304nMAssay Description:Effective concentration for binding to human metabotropic glutamate receptor 2 as determined by GTPgammaS assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetMetabotropic glutamate receptor 2(Human)
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50153741(1-(2-Hydroxy-3-propyl-4-{4-[4-(2H-tetrazol-5-yl)-p...)
Affinity DataEC50:  495nMAssay Description:Effective concentration for binding to human metabotropic glutamate receptor 2 as determined by GTPgammaS assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetMetabotropic glutamate receptor 2(Human)
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50153748(1-(2-Hydroxy-4-{1-methyl-4-[4-(2H-tetrazol-5-yl)-p...)
Affinity DataEC50:  918nMAssay Description:Effective concentration for binding to human metabotropic glutamate receptor 2 as determined by GTPgammaS assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetMetabotropic glutamate receptor 2(Human)
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50153747(1-(2-Hydroxy-3-propyl-4-{4-[4-(2H-tetrazol-5-yl)-p...)
Affinity DataEC50:  421nMAssay Description:Effective concentration for binding to human metabotropic glutamate receptor 2 as determined by GTPgammaS assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetMetabotropic glutamate receptor 2(Human)
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50153746(1-(2-Hydroxy-3-propyl-4-{4-[4-(2H-tetrazol-5-yl)-p...)
Affinity DataEC50:  939nMAssay Description:Effective concentration for binding to human metabotropic glutamate receptor 2 as determined by GTPgammaS assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetMetabotropic glutamate receptor 2(Human)
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50153745(N-{4-[4-(4-Acetyl-3-hydroxy-2-propyl-phenoxy)-buto...)
Affinity DataEC50:  1.04E+3nMAssay Description:Effective concentration for binding to human metabotropic glutamate receptor 2 as determined by GTPgammaS assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetMetabotropic glutamate receptor 2(Human)
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50153744(4-(4-Acetyl-3-hydroxy-2-propyl-phenoxy)-butyric ac...)
Affinity DataEC50:  7.52E+3nMAssay Description:Effective concentration for binding to human metabotropic glutamate receptor 2 as determined by GTPgammaS assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetMetabotropic glutamate receptor 2(Human)
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50153743(1-(2-Hydroxy-3-methyl-4-{4-[4-(2H-tetrazol-5-yl)-p...)
Affinity DataEC50:  380nMAssay Description:Effective concentration for binding to human metabotropic glutamate receptor 2 as determined by GTPgammaS assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetMetabotropic glutamate receptor 2(Human)
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50153742(1-[2-Hydroxy-4-(4-{methyl-[4-(2H-tetrazol-5-yl)-ph...)
Affinity DataEC50:  2.01E+3nMAssay Description:Effective concentration for binding to human metabotropic glutamate receptor 2 as determined by GTPgammaS assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetMetabotropic glutamate receptor 2(Human)
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50153740(1-(2-Hydroxy-3-propyl-4-{3-[4-(2H-tetrazol-5-yl)-p...)
Affinity DataEC50:  1.42E+3nMAssay Description:Effective concentration for binding to human metabotropic glutamate receptor 2 as determined by GTPgammaS assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed