Compile Data Set for Download or QSAR
Report error Found 6 Enz. Inhib. hit(s) with all data for entry = 50015256
TargetATP-binding cassette sub-family C member 8(Human)
University of Mainz

Curated by ChEMBL
LigandPNGBDBM50153520(CHEMBL1272 | AGEE-623ZW | 2-Ethoxy-4-{[(S)-3-methy...)
Affinity DataKd:  50nMAssay Description:Displacement of [3H]glibenclamide from COS-1 cells expressing Sulfonylurea receptor 1 (SUR-1)More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMedPDB3D3D Structure (crystal)
TargetATP-binding cassette sub-family C member 8(Human)
University of Mainz

Curated by ChEMBL
LigandPNGBDBM50153521(2-Methoxy-4-{[(S)-3-methyl-1-(2-piperidin-1-yl-phe...)
Affinity DataKd:  83nMAssay Description:Displacement of [3H]glibenclamide from COS-1 cells expressing Sulfonylurea receptor 1 (SUR-1)More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetATP-binding cassette sub-family C member 8(Human)
University of Mainz

Curated by ChEMBL
LigandPNGBDBM50153522(2-(2-Fluoro-ethoxy)-4-{[(S)-3-methyl-1-(2-piperidi...)
Affinity DataKd:  134nMAssay Description:Displacement of [3H]glibenclamide from COS-1 cells expressing Sulfonylurea receptor 1 (SUR-1)More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetATP-binding cassette sub-family C member 8(Human)
University of Mainz

Curated by ChEMBL
LigandPNGBDBM50153520(CHEMBL1272 | AGEE-623ZW | 2-Ethoxy-4-{[(S)-3-methy...)
Affinity DataIC50: 106nMAssay Description:In vitro displacement of [3H]glibenclamide (IC50=0.61) from COS-1 cells expressing Sulfonylurea receptor 1 (SUR-1)More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMedPDB3D3D Structure (crystal)
TargetATP-binding cassette sub-family C member 8(Human)
University of Mainz

Curated by ChEMBL
LigandPNGBDBM50153521(2-Methoxy-4-{[(S)-3-methyl-1-(2-piperidin-1-yl-phe...)
Affinity DataIC50: 163nMAssay Description:In vitro displacement of [3H]glibenclamide (IC50=0.61) from COS-1 cells expressing Sulfonylurea receptor 1 (SUR-1)More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetATP-binding cassette sub-family C member 8(Human)
University of Mainz

Curated by ChEMBL
LigandPNGBDBM50153522(2-(2-Fluoro-ethoxy)-4-{[(S)-3-methyl-1-(2-piperidi...)
Affinity DataIC50: 281nMAssay Description:In vitro displacement of [3H]glibenclamide (IC50=0.61) from COS-1 cells expressing Sulfonylurea receptor 1 (SUR-1)More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed