Compile Data Set for Download or QSAR
Report error Found 16 Enz. Inhib. hit(s) with all data for entry = 50041371
TargetIntegrin alpha-V/beta-3(Human)
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50152791((S)-2-((1S,4R)-7,7-Dimethyl-2-oxo-bicyclo[2.2.1]he...)
Affinity DataIC50: 0.100nMAssay Description:Inhibition of alpha v beta 3 receptor bindingMore data for this Ligand-Target Pair
In Depth
Date in BDB:
5/20/2013
Entry Details Article
PubMed
TargetIntegrin alpha-V/beta-3(Human)
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50152785((S)-2-Benzenesulfonylamino-3-(5-5,6,7,8-tetrahydro...)
Affinity DataIC50: 0.300nMAssay Description:Inhibition of alpha v beta 3 receptor bindingMore data for this Ligand-Target Pair
In Depth
Date in BDB:
5/20/2013
Entry Details Article
PubMed
TargetIntegrin alpha-V/beta-3(Human)
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50152786((S)-3-(5-5,6,7,8-Tetrahydro-[1,8]naphthyridin-2-yl...)
Affinity DataIC50: 0.400nMAssay Description:Inhibition of alpha v beta 3 receptor bindingMore data for this Ligand-Target Pair
In Depth
Date in BDB:
5/20/2013
Entry Details Article
PubMed
TargetIntegrin alpha-V/beta-3(Human)
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50152778((S)-2-Benzyloxycarbonylamino-3-(5-5,6,7,8-tetrahyd...)
Affinity DataIC50: 0.800nMAssay Description:Inhibition of alpha v beta 3 receptor bindingMore data for this Ligand-Target Pair
In Depth
Date in BDB:
5/20/2013
Entry Details Article
PubMed
TargetIntegrin alpha-V/beta-3(Human)
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50152781((S)-2-((1S,4R)-7,7-Dimethyl-2-oxo-bicyclo[2.2.1]he...)
Affinity DataIC50: 0.800nMAssay Description:Inhibition of binding to alpha v beta 3 receptorMore data for this Ligand-Target Pair
In Depth
Date in BDB:
5/20/2013
Entry Details Article
PubMed
TargetIntegrin alpha-V/beta-3(Human)
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50152780((S)-2-(Butane-1-sulfonylamino)-3-(5-5,6,7,8-tetrah...)
Affinity DataIC50: 2.30nMAssay Description:Inhibition of alpha v beta 3 receptor bindingMore data for this Ligand-Target Pair
In Depth
Date in BDB:
5/20/2013
Entry Details Article
PubMed
TargetIntegrin alpha-V/beta-3(Human)
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50152787((S)-2-(3-Benzyl-ureido)-9-(5,6,7,8-tetrahydro-[1,8...)
Affinity DataIC50: 4.70nMAssay Description:Inhibition of binding to alpha v beta 3 receptorMore data for this Ligand-Target Pair
In Depth
Date in BDB:
5/20/2013
Entry Details Article
PubMed
TargetIntegrin alpha-V/beta-3(Human)
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50152790((S)-2-Benzyloxycarbonylamino-9-(5,6,7,8-tetrahydro...)
Affinity DataIC50: 6.10nMAssay Description:Inhibition of binding to alpha v beta 3 receptorMore data for this Ligand-Target Pair
In Depth
Date in BDB:
5/20/2013
Entry Details Article
PubMed
TargetIntegrin alpha-V/beta-3(Human)
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50152783((S)-2-Benzenesulfonylamino-9-(5,6,7,8-tetrahydro-[...)
Affinity DataIC50: 11.2nMAssay Description:Inhibition of binding to alpha v beta 3 receptorMore data for this Ligand-Target Pair
In Depth
Date in BDB:
5/20/2013
Entry Details Article
PubMed
TargetIntegrin alpha-V/beta-3(Human)
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50152782((S)-2-Cyclohexylmethanesulfonylamino-9-(5,6,7,8-te...)
Affinity DataIC50: 18.1nMAssay Description:Inhibition of binding to alpha v beta 3 receptorMore data for this Ligand-Target Pair
In Depth
Date in BDB:
5/20/2013
Entry Details Article
PubMed
TargetIntegrin alpha-V/beta-3(Human)
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50152779((S)-2-(Butane-1-sulfonylamino)-9-(5,6,7,8-tetrahyd...)
Affinity DataIC50: 21.3nMAssay Description:Inhibition of binding to alpha v beta 3 receptorMore data for this Ligand-Target Pair
In Depth
Date in BDB:
5/20/2013
Entry Details Article
PubMed
TargetIntegrin alpha-V/beta-3(Human)
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50152789((S)-2-Phenylmethanesulfonylamino-9-(5,6,7,8-tetrah...)
Affinity DataIC50: 34.5nMAssay Description:Inhibition of binding to alpha v beta 3 receptorMore data for this Ligand-Target Pair
In Depth
Date in BDB:
5/20/2013
Entry Details Article
PubMed
TargetIntegrin alpha-V/beta-3(Human)
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50152784((S)-2-Cyclohexanesulfonylamino-9-(5,6,7,8-tetrahyd...)
Affinity DataIC50: 49.8nMAssay Description:Inhibition of binding to alpha v beta 3 receptorMore data for this Ligand-Target Pair
In Depth
Date in BDB:
5/20/2013
Entry Details Article
PubMed
TargetIntegrin alpha-V/beta-3(Human)
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50152788((S)-2-Phenylacetylamino-9-(5,6,7,8-tetrahydro-[1,8...)
Affinity DataIC50: 51.6nMAssay Description:Inhibition of binding to alpha v beta 3 receptorMore data for this Ligand-Target Pair
In Depth
Date in BDB:
5/20/2013
Entry Details Article
PubMed
TargetIntegrin alpha-V/beta-3(Human)
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50152792((S)-2-Benzoylamino-9-(5,6,7,8-tetrahydro-[1,8]naph...)
Affinity DataIC50: 71.7nMAssay Description:Inhibition of binding to alpha v beta 3 receptorMore data for this Ligand-Target Pair
In Depth
Date in BDB:
5/20/2013
Entry Details Article
PubMed
TargetIntegrin alpha-V/beta-3(Human)
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50152777((S)-2-Benzoylamino-3-(5-5,6,7,8-tetrahydro-[1,8]na...)
Affinity DataIC50: 73.8nMAssay Description:Inhibition of alpha v beta 3 receptor bindingMore data for this Ligand-Target Pair
In Depth
Date in BDB:
5/20/2013
Entry Details Article
PubMed