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Found
149
Enz. Inhib. hit(s) with all data for entry = 5475
Target
5-hydroxytryptamine receptor 2A
(Human)
Vernalis Research
Curated by
PDSP K
i
Database
Ligand
BDBM86237
(NSC_8226 | CAS_8226 | METHYLERGONOVINE)
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Affinity Data
Ki: 0.350nM
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In Depth
Date in BDB:
5/31/2012
Entry Details
Article
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PubMed
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Target
5-hydroxytryptamine receptor 2B
(Human)
Vernalis Research
Curated by
PDSP K
i
Database
Ligand
BDBM50031942
(CHEMBL1065 | Sansert | (6aR,9R)-4-Methyl-4,6,6a,7,...)
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Affinity Data
Ki: 0.360nM
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Date in BDB:
5/31/2012
Entry Details
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PubMed
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Target
5-hydroxytryptamine receptor 2B
(Human)
Vernalis Research
Curated by
PDSP K
i
Database
Ligand
BDBM86237
(NSC_8226 | CAS_8226 | METHYLERGONOVINE)
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Affinity Data
Ki: 0.460nM
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ChEBI
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Date in BDB:
5/31/2012
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PubMed
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Target
5-hydroxytryptamine receptor 2A
(Human)
Vernalis Research
Curated by
PDSP K
i
Database
Ligand
BDBM28582
([125I]2,5-dimethoxy-4-iodoamphetamine | DOI,(-) | ...)
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Affinity Data
Ki: 0.650nM
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Date in BDB:
5/31/2012
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PubMed
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Target
5-hydroxytryptamine receptor 2A
(Human)
Vernalis Research
Curated by
PDSP K
i
Database
Ligand
BDBM86427
(NSC_3981 | CAS_50-37-3 | LSD)
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Affinity Data
Ki: 0.760nM
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Date in BDB:
5/31/2012
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PubMed
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Target
5-hydroxytryptamine receptor 2A
(Human)
Vernalis Research
Curated by
PDSP K
i
Database
Ligand
BDBM28582
([125I]2,5-dimethoxy-4-iodoamphetamine | DOI,(-) | ...)
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Affinity Data
Ki: 0.930nM
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Date in BDB:
5/31/2012
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PubMed
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Target
5-hydroxytryptamine receptor 2A
(Human)
Vernalis Research
Curated by
PDSP K
i
Database
Ligand
BDBM86529
(CAS_113-15-5 | NSC_3251 | ERGOTAMINE)
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Affinity Data
Ki: 0.980nM
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Date in BDB:
5/31/2012
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Target
5-hydroxytryptamine receptor 2B
(Human)
Vernalis Research
Curated by
PDSP K
i
Database
Ligand
BDBM86427
(NSC_3981 | CAS_50-37-3 | LSD)
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Affinity Data
Ki: 0.980nM
More data for this Ligand-Target Pair
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Date in BDB:
5/31/2012
Entry Details
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Target
5-hydroxytryptamine receptor 2B
(Human)
Vernalis Research
Curated by
PDSP K
i
Database
Ligand
BDBM50249134
(RS-127445 | CHEMBL473186 | 4-(4-fluoronaphthalen-1...)
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Affinity Data
Ki: 1.07nM
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CHEMBL
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Date in BDB:
5/31/2012
Entry Details
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Target
5-hydroxytryptamine receptor 2C
(Human)
Vernalis Research
Curated by
PDSP K
i
Database
Ligand
BDBM86427
(NSC_3981 | CAS_50-37-3 | LSD)
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Affinity Data
Ki: 1.10nM
More data for this Ligand-Target Pair
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Date in BDB:
5/31/2012
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Target
5-hydroxytryptamine receptor 2A
(Human)
Vernalis Research
Curated by
PDSP K
i
Database
Ligand
BDBM50005257
(2-(4-Bromo-2,5-dimethoxy-phenyl)-1-methyl-ethylami...)
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Ki: 1.17nM
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Date in BDB:
5/31/2012
Entry Details
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PubMed
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Target
5-hydroxytryptamine receptor 2B
(Human)
Vernalis Research
Curated by
PDSP K
i
Database
Ligand
BDBM86529
(CAS_113-15-5 | NSC_3251 | ERGOTAMINE)
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Affinity Data
Ki: 1.29nM
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Date in BDB:
5/31/2012
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PubMed
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Target
5-hydroxytryptamine receptor 2B
(Human)
Vernalis Research
Curated by
PDSP K
i
Database
Ligand
BDBM86523
(CAS_17692-51-2 | NSC_28693 | METERGOLINE)
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Ki: 1.78nM
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Date in BDB:
5/31/2012
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PubMed
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Target
5-hydroxytryptamine receptor 2C
(Human)
Vernalis Research
Curated by
PDSP K
i
Database
Ligand
BDBM86523
(CAS_17692-51-2 | NSC_28693 | METERGOLINE)
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Affinity Data
Ki: 1.78nM
More data for this Ligand-Target Pair
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ChEBI
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Date in BDB:
5/31/2012
Entry Details
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PubMed
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Target
5-hydroxytryptamine receptor 2C
(Human)
Vernalis Research
Curated by
PDSP K
i
Database
Ligand
BDBM86527
(CAS_64795-35-3 | NSC_68848 | MESULERGINE)
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Affinity Data
Ki: 1.82nM
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Date in BDB:
5/31/2012
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Target
5-hydroxytryptamine receptor 2A
(Human)
Vernalis Research
Curated by
PDSP K
i
Database
Ligand
BDBM50232153
(CHEMBL257283 | MDL-100907 | MDL 100907 | (1-(4-flu...)
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Ki: 1.86nM
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CHEMBL
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Date in BDB:
5/31/2012
Entry Details
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PubMed
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Target
5-hydroxytryptamine receptor 2C
(Human)
Vernalis Research
Curated by
PDSP K
i
Database
Ligand
BDBM86529
(CAS_113-15-5 | NSC_3251 | ERGOTAMINE)
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Affinity Data
Ki: 1.91nM
More data for this Ligand-Target Pair
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Date in BDB:
5/31/2012
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PubMed
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Target
5-hydroxytryptamine receptor 2B
(Human)
Vernalis Research
Curated by
PDSP K
i
Database
Ligand
BDBM78940
(methanesulfonic acid;1-methyl-4-(3-methylsulfanyl-...)
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Affinity Data
Ki: 2.09nM
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In Depth
Date in BDB:
5/31/2012
Entry Details
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Target
5-hydroxytryptamine receptor 2B
(Human)
Vernalis Research
Curated by
PDSP K
i
Database
Ligand
BDBM50001775
(cid_5074 | Ritanserine | 6-(2-{4-[Bis-(4-fluoro-ph...)
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Affinity Data
Ki: 2.14nM
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In Depth
Date in BDB:
5/31/2012
Entry Details
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PubMed
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Target
5-hydroxytryptamine receptor 2C
(Human)
Vernalis Research
Curated by
PDSP K
i
Database
Ligand
BDBM50060418
(CHEMBL276140 | SB 221284 | 5-Methylsulfanyl-6-trif...)
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Affinity Data
Ki: 2.19nM
More data for this Ligand-Target Pair
Target Info
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CHEMBL
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In Depth
Date in BDB:
5/31/2012
Entry Details
Article
Copy Entry DOI
PubMed
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Target
5-hydroxytryptamine receptor 2A
(Human)
Vernalis Research
Curated by
PDSP K
i
Database
Ligand
BDBM86523
(CAS_17692-51-2 | NSC_28693 | METERGOLINE)
Copy SMILES
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Affinity Data
Ki: 2.29nM
More data for this Ligand-Target Pair
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ChEBI
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In Depth
Date in BDB:
5/31/2012
Entry Details
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PubMed
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Target
5-hydroxytryptamine receptor 2B
(Human)
Vernalis Research
Curated by
PDSP K
i
Database
Ligand
BDBM50060418
(CHEMBL276140 | SB 221284 | 5-Methylsulfanyl-6-trif...)
Copy SMILES
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Affinity Data
Ki: 2.45nM
More data for this Ligand-Target Pair
Target Info
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In Depth
Date in BDB:
5/31/2012
Entry Details
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Copy Entry DOI
PubMed
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Target
5-hydroxytryptamine receptor 2C
(Human)
Vernalis Research
Curated by
PDSP K
i
Database
Ligand
BDBM81781
(5-HT,omega-N-Me | 5-HT,a-Me)
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Affinity Data
Ki: 2.69nM
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Date in BDB:
5/31/2012
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PubMed
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Target
5-hydroxytryptamine receptor 2A
(Human)
Vernalis Research
Curated by
PDSP K
i
Database
Ligand
BDBM78940
(methanesulfonic acid;1-methyl-4-(3-methylsulfanyl-...)
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Affinity Data
Ki: 3.16nM
More data for this Ligand-Target Pair
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Date in BDB:
5/31/2012
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PubMed
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Target
5-hydroxytryptamine receptor 2B
(Human)
Vernalis Research
Curated by
PDSP K
i
Database
Ligand
BDBM86527
(CAS_64795-35-3 | NSC_68848 | MESULERGINE)
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Affinity Data
Ki: 3.47nM
More data for this Ligand-Target Pair
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Date in BDB:
5/31/2012
Entry Details
Article
Copy Entry DOI
PubMed
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Target
5-hydroxytryptamine receptor 2A
(Human)
Vernalis Research
Curated by
PDSP K
i
Database
Ligand
BDBM50031942
(CHEMBL1065 | Sansert | (6aR,9R)-4-Methyl-4,6,6a,7,...)
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Affinity Data
Ki: 3.98nM
More data for this Ligand-Target Pair
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Date in BDB:
5/31/2012
Entry Details
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Copy Entry DOI
PubMed
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Target
5-hydroxytryptamine receptor 2C
(Human)
Vernalis Research
Curated by
PDSP K
i
Database
Ligand
BDBM78940
(methanesulfonic acid;1-methyl-4-(3-methylsulfanyl-...)
Copy SMILES
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Affinity Data
Ki: 4.47nM
More data for this Ligand-Target Pair
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ChEBI
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In Depth
Date in BDB:
5/31/2012
Entry Details
Article
Copy Entry DOI
PubMed
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Target
5-hydroxytryptamine receptor 2C
(Human)
Vernalis Research
Curated by
PDSP K
i
Database
Ligand
BDBM50031942
(CHEMBL1065 | Sansert | (6aR,9R)-4-Methyl-4,6,6a,7,...)
Copy SMILES
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Affinity Data
Ki: 4.47nM
More data for this Ligand-Target Pair
Target Info
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Date in BDB:
5/31/2012
Entry Details
Article
Copy Entry DOI
PubMed
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Target
5-hydroxytryptamine receptor 2A
(Human)
Vernalis Research
Curated by
PDSP K
i
Database
Ligand
BDBM50001775
(cid_5074 | Ritanserine | 6-(2-{4-[Bis-(4-fluoro-ph...)
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Affinity Data
Ki: 4.57nM
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ChEBI
CHEMBL
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In Depth
Date in BDB:
5/31/2012
Entry Details
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PubMed
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Target
5-hydroxytryptamine receptor 2C
(Human)
Vernalis Research
Curated by
PDSP K
i
Database
Ligand
BDBM86237
(NSC_8226 | CAS_8226 | METHYLERGONOVINE)
Copy SMILES
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Ki: 4.57nM
More data for this Ligand-Target Pair
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Date in BDB:
5/31/2012
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PubMed
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Target
5-hydroxytryptamine receptor 2C
(Human)
Vernalis Research
Curated by
PDSP K
i
Database
Ligand
BDBM85098
(N-[5-[5-(2,4-Dioxo-1,3,8-triazaspiro[4.5]decan-8-y...)
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Ki: 5.01nM
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ChEBI
PC cid
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In Depth
Date in BDB:
5/31/2012
Entry Details
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PubMed
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Target
5-hydroxytryptamine receptor 2B
(Human)
Vernalis Research
Curated by
PDSP K
i
Database
Ligand
BDBM85528
(NSC_3045226 | CAS_3045226 | Ro 60-0175)
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Ki: 5.37nM
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Date in BDB:
5/31/2012
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Target
5-hydroxytryptamine receptor 2C
(Human)
Vernalis Research
Curated by
PDSP K
i
Database
Ligand
BDBM28582
([125I]2,5-dimethoxy-4-iodoamphetamine | DOI,(-) | ...)
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Ki: 5.37nM
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Date in BDB:
5/31/2012
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Target
5-hydroxytryptamine receptor 2C
(Human)
Vernalis Research
Curated by
PDSP K
i
Database
Ligand
BDBM31005
(MIANSERIN HYDROCHLORIDE | SMR000058472 | MLS000069...)
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Ki: 5.5nM
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Date in BDB:
5/31/2012
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Target
5-hydroxytryptamine receptor 2C
(Human)
Vernalis Research
Curated by
PDSP K
i
Database
Ligand
BDBM50144840
(CHEMBL309760 | (S)-2-(6-Bromo-2,3-dihydro-indol-1-...)
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Ki: 5.62nM
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CHEMBL
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In Depth
Date in BDB:
5/31/2012
Entry Details
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PubMed
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Target
5-hydroxytryptamine receptor 2C
(Human)
Vernalis Research
Curated by
PDSP K
i
Database
Ligand
BDBM10755
([3H]-5-HT | 5-Hydroxy Tryptamine | 2-imino-1-methy...)
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Affinity Data
Ki: 5.75nM
More data for this Ligand-Target Pair
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Date in BDB:
5/31/2012
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Copy Entry DOI
PubMed
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Target
5-hydroxytryptamine receptor 2C
(Human)
Vernalis Research
Curated by
PDSP K
i
Database
Ligand
BDBM85528
(NSC_3045226 | CAS_3045226 | Ro 60-0175)
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Affinity Data
Ki: 6.03nM
More data for this Ligand-Target Pair
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In Depth
Date in BDB:
5/31/2012
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PubMed
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Target
5-hydroxytryptamine receptor 2C
(Human)
Vernalis Research
Curated by
PDSP K
i
Database
Ligand
BDBM50005257
(2-(4-Bromo-2,5-dimethoxy-phenyl)-1-methyl-ethylami...)
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Affinity Data
Ki: 6.31nM
More data for this Ligand-Target Pair
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In Depth
Date in BDB:
5/31/2012
Entry Details
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Copy Entry DOI
PubMed
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Target
5-hydroxytryptamine receptor 2C
(Human)
Vernalis Research
Curated by
PDSP K
i
Database
Ligand
BDBM50001775
(cid_5074 | Ritanserine | 6-(2-{4-[Bis-(4-fluoro-ph...)
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Ki: 6.61nM
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Date in BDB:
5/31/2012
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Target
5-hydroxytryptamine receptor 2B
(Human)
Vernalis Research
Curated by
PDSP K
i
Database
Ligand
BDBM81781
(5-HT,omega-N-Me | 5-HT,a-Me)
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Ki: 6.92nM
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Date in BDB:
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Target
5-hydroxytryptamine receptor 2C
(Human)
Vernalis Research
Curated by
PDSP K
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Database
Ligand
BDBM85097
(CAS_181632-25-7 | CHEMBL14563 | SB 242084)
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Ki: 7.08nM
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Target
5-hydroxytryptamine receptor 2C
(Human)
Vernalis Research
Curated by
PDSP K
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Database
Ligand
BDBM86526
(ORG-37684)
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Ki: 7.59nM
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Date in BDB:
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Target
5-hydroxytryptamine receptor 2C
(Human)
Vernalis Research
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PDSP K
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Database
Ligand
BDBM85099
(SDZ SER 082 FUMARATE | CAS_141474-54-6 | SDZ SER-0...)
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Ki: 7.59nM
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Date in BDB:
5/31/2012
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Target
5-hydroxytryptamine receptor 2A
(Human)
Vernalis Research
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PDSP K
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Ligand
BDBM21395
(3-(2-{4-[(4-fluorophenyl)carbonyl]piperidin-1-yl}e...)
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Ki: 8.13nM
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Date in BDB:
5/31/2012
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Target
5-hydroxytryptamine receptor 2C
(Human)
Vernalis Research
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PDSP K
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Database
Ligand
BDBM28582
([125I]2,5-dimethoxy-4-iodoamphetamine | DOI,(-) | ...)
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Ki: 8.32nM
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Date in BDB:
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Target
5-hydroxytryptamine receptor 2B
(Human)
Vernalis Research
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PDSP K
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Database
Ligand
BDBM22869
(6-chloro-10-(4-methylpiperazin-1-yl)-2,9-diazatric...)
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Ki: 10.2nM
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Date in BDB:
5/31/2012
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Target
5-hydroxytryptamine receptor 2B
(Human)
Vernalis Research
Curated by
PDSP K
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Database
Ligand
BDBM31005
(MIANSERIN HYDROCHLORIDE | SMR000058472 | MLS000069...)
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Ki: 12.0nM
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Date in BDB:
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Target
5-hydroxytryptamine receptor 2B
(Human)
Vernalis Research
Curated by
PDSP K
i
Database
Ligand
BDBM10755
([3H]-5-HT | 5-Hydroxy Tryptamine | 2-imino-1-methy...)
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Ki: 13.5nM
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Date in BDB:
5/31/2012
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Target
5-hydroxytryptamine receptor 2C
(Human)
Vernalis Research
Curated by
PDSP K
i
Database
Ligand
BDBM22869
(6-chloro-10-(4-methylpiperazin-1-yl)-2,9-diazatric...)
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Ki: 13.5nM
More data for this Ligand-Target Pair
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Date in BDB:
5/31/2012
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Target
5-hydroxytryptamine receptor 2C
(Human)
Vernalis Research
Curated by
PDSP K
i
Database
Ligand
BDBM50001915
(mCPP | 1-(3-chlorophenyl)piperazine | CHEMBL478 | ...)
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Ki: 14.1nM
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Date in BDB:
5/31/2012
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