Compile Data Set for Download or QSAR
Report error Found 28 Enz. Inhib. hit(s) with all data for entry = 50015033
TargetC-X-C chemokine receptor type 1(Human)
Johnson and Johnson Pharmaceutical Research and Development

Curated by ChEMBL
LigandPNGBDBM50150572(1-(2-Bromo-phenyl)-3-(2,4-dihydroxy-phenyl)-urea |...)
Affinity DataIC50: 22nMAssay Description:Inhibitory concentration against interleukin-8 receptor of human neutrophils by using [125I]IL-8 (0.125 nM) as radioligandMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetC-X-C chemokine receptor type 1(Human)
Johnson and Johnson Pharmaceutical Research and Development

Curated by ChEMBL
LigandPNGBDBM50150573(1-{4-[5-(4-Chloro-phenyl)-isoxazol-3-yl]-phenoxyme...)
Affinity DataIC50: 1.60E+3nMAssay Description:Inhibitory concentration against interleukin-8 receptor of human neutrophils by using [125I]IL-8 (0.125 nM) as radioligandMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetC-X-C chemokine receptor type 1(Human)
Johnson and Johnson Pharmaceutical Research and Development

Curated by ChEMBL
LigandPNGBDBM50150561(1-(3-{4-[3-(4-Fluoro-phenyl)-isoxazol-5-yl]-phenox...)
Affinity DataIC50: 2.00E+3nMAssay Description:Inhibitory concentration against interleukin-8 receptor of human neutrophils by using [125I]IL-8 (0.125 nM) as radioligandMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetC-X-C chemokine receptor type 1(Human)
Johnson and Johnson Pharmaceutical Research and Development

Curated by ChEMBL
LigandPNGBDBM50150558(1-(3-{4-[3-(4-Chloro-phenyl)-isoxazol-5-yl]-phenox...)
Affinity DataIC50: 2.10E+3nMAssay Description:Inhibitory concentration against interleukin-8 receptor of human neutrophils by using [125I]IL-8 (0.125 nM) as radioligandMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetC-X-C chemokine receptor type 1(Human)
Johnson and Johnson Pharmaceutical Research and Development

Curated by ChEMBL
LigandPNGBDBM50150555(1-(3-{4-[3-(4-Chloro-phenyl)-[1,2,4]oxadiazol-5-yl...)
Affinity DataIC50: 2.50E+3nMAssay Description:Inhibitory concentration against interleukin-8 receptor of human neutrophils by using [125I]IL-8 (0.125 nM) as radioligandMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetC-X-C chemokine receptor type 1(Human)
Johnson and Johnson Pharmaceutical Research and Development

Curated by ChEMBL
LigandPNGBDBM50150563({4-[5-(4-Chloro-phenyl)-isoxazol-3-yl]-phenoxymeth...)
Affinity DataIC50: 2.70E+3nMAssay Description:Inhibitory concentration against interleukin-8 receptor of human neutrophils by using [125I]IL-8 (0.125 nM) as radioligandMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetC-X-C chemokine receptor type 1(Human)
Johnson and Johnson Pharmaceutical Research and Development

Curated by ChEMBL
LigandPNGBDBM50150553(1-Methyl-4-{3-[4-(3-phenyl-isoxazol-5-yl)-phenoxy]...)
Affinity DataIC50: 3.00E+3nMAssay Description:Inhibitory concentration against interleukin-8 receptor of human neutrophils by using [125I]IL-8 (0.125 nM) as radioligandMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetC-X-C chemokine receptor type 1(Human)
Johnson and Johnson Pharmaceutical Research and Development

Curated by ChEMBL
LigandPNGBDBM50150559({4-[5-(4-Fluoro-phenyl)-isoxazol-3-yl]-phenoxymeth...)
Affinity DataIC50: 3.10E+3nMAssay Description:Inhibitory concentration against interleukin-8 receptor of human neutrophils by using [125I]IL-8 (0.125 nM) as radioligandMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetC-X-C chemokine receptor type 1(Human)
Johnson and Johnson Pharmaceutical Research and Development

Curated by ChEMBL
LigandPNGBDBM50150558(1-(3-{4-[3-(4-Chloro-phenyl)-isoxazol-5-yl]-phenox...)
Affinity DataIC50: 3.60E+3nMAssay Description:Inhibition of interleukin-8 induced elastase release from human neutrophilsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetC-X-C chemokine receptor type 1(Human)
Johnson and Johnson Pharmaceutical Research and Development

Curated by ChEMBL
LigandPNGBDBM50150561(1-(3-{4-[3-(4-Fluoro-phenyl)-isoxazol-5-yl]-phenox...)
Affinity DataIC50: 3.80E+3nMAssay Description:Inhibition of interleukin-8 induced elastase release from human neutrophilsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetC-X-C chemokine receptor type 1(Human)
Johnson and Johnson Pharmaceutical Research and Development

Curated by ChEMBL
LigandPNGBDBM50150569((3-{4-[3-(4-Chloro-phenyl)-isoxazol-5-yl]-phenoxy}...)
Affinity DataIC50: 3.90E+3nMAssay Description:Inhibitory concentration against interleukin-8 receptor of human neutrophils by using [125I]IL-8 (0.125 nM) as radioligandMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetC-X-C chemokine receptor type 1(Human)
Johnson and Johnson Pharmaceutical Research and Development

Curated by ChEMBL
LigandPNGBDBM50150559({4-[5-(4-Fluoro-phenyl)-isoxazol-3-yl]-phenoxymeth...)
Affinity DataIC50: 4.00E+3nMAssay Description:Inhibition of interleukin-8 induced elastase release from human neutrophilsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetC-X-C chemokine receptor type 1(Human)
Johnson and Johnson Pharmaceutical Research and Development

Curated by ChEMBL
LigandPNGBDBM50150574({2-[5-(4-Chloro-phenyl)-isoxazol-3-yl]-phenoxymeth...)
Affinity DataIC50: 4.40E+3nMAssay Description:Inhibitory concentration against interleukin-8 receptor of human neutrophils by using [125I]IL-8 (0.125 nM) as radioligandMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetC-X-C chemokine receptor type 1(Human)
Johnson and Johnson Pharmaceutical Research and Development

Curated by ChEMBL
LigandPNGBDBM50150555(1-(3-{4-[3-(4-Chloro-phenyl)-[1,2,4]oxadiazol-5-yl...)
Affinity DataIC50: 4.50E+3nMAssay Description:Inhibition of interleukin-8 induced elastase release from human neutrophilsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetC-X-C chemokine receptor type 1(Human)
Johnson and Johnson Pharmaceutical Research and Development

Curated by ChEMBL
LigandPNGBDBM50150567(1-[4-(5-Phenyl-isoxazol-3-yl)-phenoxymethyl]-piper...)
Affinity DataIC50: 5.40E+3nMAssay Description:Inhibitory concentration against interleukin-8 receptor of human neutrophils by using [125I]IL-8 (0.125 nM) as radioligandMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetC-X-C chemokine receptor type 1(Human)
Johnson and Johnson Pharmaceutical Research and Development

Curated by ChEMBL
LigandPNGBDBM50150556(1-Methyl-4-(3-{4-[3-(3-trifluoromethyl-phenyl)-iso...)
Affinity DataIC50: 6.00E+3nMAssay Description:Inhibitory concentration against interleukin-8 receptor of human neutrophils by using [125I]IL-8 (0.125 nM) as radioligandMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetC-X-C chemokine receptor type 1(Human)
Johnson and Johnson Pharmaceutical Research and Development

Curated by ChEMBL
LigandPNGBDBM50150566(1-Methyl-4-[4-(5-phenyl-isoxazol-3-yl)-phenoxymeth...)
Affinity DataIC50: 6.20E+3nMAssay Description:Inhibitory concentration against interleukin-8 receptor of human neutrophils by using [125I]IL-8 (0.125 nM) as radioligandMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetC-X-C chemokine receptor type 1(Human)
Johnson and Johnson Pharmaceutical Research and Development

Curated by ChEMBL
LigandPNGBDBM50150568(Dimethyl-{3-[4-(3-phenyl-isoxazol-5-yl)-phenoxy]-p...)
Affinity DataIC50: 6.70E+3nMAssay Description:Inhibitory concentration against interleukin-8 receptor of human neutrophils by using [125I]IL-8 (0.125 nM) as radioligandMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetC-X-C chemokine receptor type 1(Human)
Johnson and Johnson Pharmaceutical Research and Development

Curated by ChEMBL
LigandPNGBDBM50150570(1-Methyl-4-[4-(5-phenyl-isoxazol-3-yl)-phenoxymeth...)
Affinity DataIC50: 7.60E+3nMAssay Description:Inhibitory concentration against interleukin-8 receptor of human neutrophils by using [125I]IL-8 (0.125 nM) as radioligandMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetC-X-C chemokine receptor type 1(Human)
Johnson and Johnson Pharmaceutical Research and Development

Curated by ChEMBL
LigandPNGBDBM50150560({3-[5-(4-Chloro-phenyl)-isoxazol-3-yl]-phenoxymeth...)
Affinity DataIC50: 8.10E+3nMAssay Description:Inhibitory concentration against interleukin-8 receptor of human neutrophils by using [125I]IL-8 (0.125 nM) as radioligandMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetC-X-C chemokine receptor type 1(Human)
Johnson and Johnson Pharmaceutical Research and Development

Curated by ChEMBL
LigandPNGBDBM50150565(1-(2-{4-[5-(4-Chloro-phenyl)-isoxazol-3-yl]-phenox...)
Affinity DataIC50: 8.90E+3nMAssay Description:Inhibitory concentration against interleukin-8 receptor of human neutrophils by using [125I]IL-8 (0.125 nM) as radioligandMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetC-X-C chemokine receptor type 1(Human)
Johnson and Johnson Pharmaceutical Research and Development

Curated by ChEMBL
LigandPNGBDBM50150571(1-(3-{4-[3-(3-Chloro-phenyl)-isoxazol-5-yl]-phenox...)
Affinity DataIC50: 9.60E+3nMAssay Description:Inhibitory concentration against interleukin-8 receptor of human neutrophils by using [125I]IL-8 (0.125 nM) as radioligandMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetC-X-C chemokine receptor type 1(Human)
Johnson and Johnson Pharmaceutical Research and Development

Curated by ChEMBL
LigandPNGBDBM50150557(1-(3-{4-[3-(4-Fluoro-phenyl)-[1,2,4]oxadiazol-5-yl...)
Affinity DataIC50: 1.05E+4nMAssay Description:Inhibitory concentration against interleukin-8 receptor of human neutrophils by using [125I]IL-8 (0.125 nM) as radioligandMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetC-X-C chemokine receptor type 1(Human)
Johnson and Johnson Pharmaceutical Research and Development

Curated by ChEMBL
LigandPNGBDBM50150564(Dimethyl-[4-(5-phenyl-isoxazol-3-yl)-phenoxymethyl...)
Affinity DataIC50: 1.06E+4nMAssay Description:Inhibitory concentration against interleukin-8 receptor of human neutrophils by using [125I]IL-8 (0.125 nM) as radioligandMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetC-X-C chemokine receptor type 1(Human)
Johnson and Johnson Pharmaceutical Research and Development

Curated by ChEMBL
LigandPNGBDBM50150575(1-Methyl-4-[4-(5-pyridin-2-yl-isoxazol-3-yl)-pheno...)
Affinity DataIC50: 1.15E+4nMAssay Description:Inhibitory concentration against interleukin-8 receptor of human neutrophils by using [125I]IL-8 (0.125 nM) as radioligandMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetC-X-C chemokine receptor type 1(Human)
Johnson and Johnson Pharmaceutical Research and Development

Curated by ChEMBL
LigandPNGBDBM50150562(Dimethyl-{4-[5-(4-nitro-phenyl)-isoxazol-3-yl]-phe...)
Affinity DataIC50: 1.21E+4nMAssay Description:Inhibitory concentration against interleukin-8 receptor of human neutrophils by using [125I]IL-8 (0.125 nM) as radioligandMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetC-X-C chemokine receptor type 1(Human)
Johnson and Johnson Pharmaceutical Research and Development

Curated by ChEMBL
LigandPNGBDBM50150576(1-Methyl-4-(3-{4-[3-(4-phenoxy-phenyl)-isoxazol-5-...)
Affinity DataIC50: 2.27E+4nMAssay Description:Inhibitory concentration against interleukin-8 receptor of human neutrophils by using [125I]IL-8 (0.125 nM) as radioligandMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetC-X-C chemokine receptor type 1(Human)
Johnson and Johnson Pharmaceutical Research and Development

Curated by ChEMBL
LigandPNGBDBM50150554(4-(3-{4-[3-(4-Chloro-phenyl)-[1,2,4]oxadiazol-5-yl...)
Affinity DataIC50: 2.50E+4nMAssay Description:Inhibitory concentration against interleukin-8 receptor of human neutrophils by using [125I]IL-8 (0.125 nM) as radioligandMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed