Compile Data Set for Download or QSAR
Report error Found 20 Enz. Inhib. hit(s) with all data for entry = 3311
TargetE3 ubiquitin-protein ligase Mdm2(Human)
Schering-Plough Research Institute

LigandChemical structure of BindingDB Monomer ID 31225BDBM31225(2-phenoxybenzoyltryptophan derivative, R5C3)
Affinity DataKi:  100nM ΔG°:  -39.7kJ/molepH: 7.4 T: 2°CAssay Description:Ki values were determined from a competition experiment in which serial dilutions of inhibitor were added to compete against a fixed concentration (1...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/16/2009
Entry Details Article
PubMed
TargetE3 ubiquitin-protein ligase Mdm2(Human)
Schering-Plough Research Institute

LigandChemical structure of BindingDB Monomer ID 31224BDBM31224(2-phenoxybenzoyltryptophan derivative, R5C2)
Affinity DataKi:  200nM ΔG°:  -38.0kJ/molepH: 7.4 T: 2°CAssay Description:Ki values were determined from a competition experiment in which serial dilutions of inhibitor were added to compete against a fixed concentration (1...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/16/2009
Entry Details Article
PubMed
TargetE3 ubiquitin-protein ligase Mdm2(Human)
Schering-Plough Research Institute

LigandChemical structure of BindingDB Monomer ID 31216BDBM31216(2-phenoxybenzoyltryptophan derivative, R3C2)
Affinity DataKi:  400nM ΔG°:  -36.3kJ/molepH: 7.4 T: 2°CAssay Description:Ki values were determined from a competition experiment in which serial dilutions of inhibitor were added to compete against a fixed concentration (1...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/16/2009
Entry Details Article
PubMed
TargetE3 ubiquitin-protein ligase Mdm2(Human)
Schering-Plough Research Institute

LigandChemical structure of BindingDB Monomer ID 31209BDBM31209(2-phenoxybenzoyltryptophan derivative, R1C3)
Affinity DataKi:  500nM ΔG°:  -35.7kJ/molepH: 7.4 T: 2°CAssay Description:Ki values were determined from a competition experiment in which serial dilutions of inhibitor were added to compete against a fixed concentration (1...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/16/2009
Entry Details Article
PubMed
TargetE3 ubiquitin-protein ligase Mdm2(Human)
Schering-Plough Research Institute

LigandChemical structure of BindingDB Monomer ID 31220BDBM31220(2-phenoxybenzoyltryptophan derivative, R4C2)
Affinity DataKi:  600nM ΔG°:  -35.3kJ/molepH: 7.4 T: 2°CAssay Description:Ki values were determined from a competition experiment in which serial dilutions of inhibitor were added to compete against a fixed concentration (1...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/16/2009
Entry Details Article
PubMed
TargetE3 ubiquitin-protein ligase Mdm2(Human)
Schering-Plough Research Institute

LigandChemical structure of BindingDB Monomer ID 31221BDBM31221(2-phenoxybenzoyltryptophan derivative, R4C3)
Affinity DataKi:  600nM ΔG°:  -35.3kJ/molepH: 7.4 T: 2°CAssay Description:Ki values were determined from a competition experiment in which serial dilutions of inhibitor were added to compete against a fixed concentration (1...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/16/2009
Entry Details Article
PubMed
TargetE3 ubiquitin-protein ligase Mdm2(Human)
Schering-Plough Research Institute

LigandChemical structure of BindingDB Monomer ID 31210BDBM31210(2-phenoxybenzoyltryptophan derivative, R1C4)
Affinity DataKi:  600nM ΔG°:  -35.3kJ/molepH: 7.4 T: 2°CAssay Description:Ki values were determined from a competition experiment in which serial dilutions of inhibitor were added to compete against a fixed concentration (1...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/16/2009
Entry Details Article
PubMed
TargetE3 ubiquitin-protein ligase Mdm2(Human)
Schering-Plough Research Institute

LigandChemical structure of BindingDB Monomer ID 31226BDBM31226(2-phenoxybenzoyltryptophan derivative, R5C4)
Affinity DataKi:  600nM ΔG°:  -35.3kJ/molepH: 7.4 T: 2°CAssay Description:Ki values were determined from a competition experiment in which serial dilutions of inhibitor were added to compete against a fixed concentration (1...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/16/2009
Entry Details Article
PubMed
TargetE3 ubiquitin-protein ligase Mdm2(Human)
Schering-Plough Research Institute

LigandChemical structure of BindingDB Monomer ID 31213BDBM31213(2-phenoxybenzoyltryptophan derivative, R2C3)
Affinity DataKi:  600nM ΔG°:  -35.3kJ/molepH: 7.4 T: 2°CAssay Description:Ki values were determined from a competition experiment in which serial dilutions of inhibitor were added to compete against a fixed concentration (1...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/16/2009
Entry Details Article
PubMed
TargetE3 ubiquitin-protein ligase Mdm2(Human)
Schering-Plough Research Institute

LigandChemical structure of BindingDB Monomer ID 31208BDBM31208(2-phenoxybenzoyltryptophan derivative, R1C2)
Affinity DataKi:  800nM ΔG°:  -34.6kJ/molepH: 7.4 T: 2°CAssay Description:Ki values were determined from a competition experiment in which serial dilutions of inhibitor were added to compete against a fixed concentration (1...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/16/2009
Entry Details Article
PubMed
TargetE3 ubiquitin-protein ligase Mdm2(Human)
Schering-Plough Research Institute

LigandChemical structure of BindingDB Monomer ID 31212BDBM31212(2-phenoxybenzoyltryptophan derivative, R2C2)
Affinity DataKi:  800nM ΔG°:  -34.6kJ/molepH: 7.4 T: 2°CAssay Description:Ki values were determined from a competition experiment in which serial dilutions of inhibitor were added to compete against a fixed concentration (1...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/16/2009
Entry Details Article
PubMed
TargetE3 ubiquitin-protein ligase Mdm2(Human)
Schering-Plough Research Institute

LigandChemical structure of BindingDB Monomer ID 31217BDBM31217(2-phenoxybenzoyltryptophan derivative, R3C3)
Affinity DataKi:  800nM ΔG°:  -34.6kJ/molepH: 7.4 T: 2°CAssay Description:Ki values were determined from a competition experiment in which serial dilutions of inhibitor were added to compete against a fixed concentration (1...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/16/2009
Entry Details Article
PubMed
TargetE3 ubiquitin-protein ligase Mdm2(Human)
Schering-Plough Research Institute

LigandChemical structure of BindingDB Monomer ID 31222BDBM31222(2-phenoxybenzoyltryptophan derivative, R4C4)
Affinity DataKi:  1.00E+3nM ΔG°:  -34.0kJ/molepH: 7.4 T: 2°CAssay Description:Ki values were determined from a competition experiment in which serial dilutions of inhibitor were added to compete against a fixed concentration (1...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/16/2009
Entry Details Article
PubMed
TargetE3 ubiquitin-protein ligase Mdm2(Human)
Schering-Plough Research Institute

LigandChemical structure of BindingDB Monomer ID 31214BDBM31214(2-phenoxybenzoyltryptophan derivative, R2C4)
Affinity DataKi:  1.00E+3nM ΔG°:  -34.0kJ/molepH: 7.4 T: 2°CAssay Description:Ki values were determined from a competition experiment in which serial dilutions of inhibitor were added to compete against a fixed concentration (1...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/16/2009
Entry Details Article
PubMed
TargetE3 ubiquitin-protein ligase Mdm2(Human)
Schering-Plough Research Institute

LigandChemical structure of BindingDB Monomer ID 31218BDBM31218(2-phenoxybenzoyltryptophan derivative, R3C4)
Affinity DataKi:  2.00E+3nM ΔG°:  -32.3kJ/molepH: 7.4 T: 2°CAssay Description:Ki values were determined from a competition experiment in which serial dilutions of inhibitor were added to compete against a fixed concentration (1...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/16/2009
Entry Details Article
PubMed
TargetE3 ubiquitin-protein ligase Mdm2(Human)
Schering-Plough Research Institute

LigandChemical structure of BindingDB Monomer ID 31207BDBM31207(2-phenoxybenzoyltryptophan derivative, R1C1)
Affinity DataKi:  3.00E+3nM ΔG°:  -31.3kJ/molepH: 7.4 T: 2°CAssay Description:Ki values were determined from a competition experiment in which serial dilutions of inhibitor were added to compete against a fixed concentration (1...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/16/2009
Entry Details Article
PubMed
TargetE3 ubiquitin-protein ligase Mdm2(Human)
Schering-Plough Research Institute

LigandChemical structure of BindingDB Monomer ID 31211BDBM31211(2-phenoxybenzoyltryptophan derivative, R2C1)
Affinity DataKi:  6.00E+3nM ΔG°:  -29.6kJ/molepH: 7.4 T: 2°CAssay Description:Ki values were determined from a competition experiment in which serial dilutions of inhibitor were added to compete against a fixed concentration (1...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/16/2009
Entry Details Article
PubMed
TargetE3 ubiquitin-protein ligase Mdm2(Human)
Schering-Plough Research Institute

LigandChemical structure of BindingDB Monomer ID 31223BDBM31223(2-phenoxybenzoyltryptophan derivative, R5C1)
Affinity DataKi:  1.00E+4nM ΔG°:  -28.3kJ/molepH: 7.4 T: 2°CAssay Description:Ki values were determined from a competition experiment in which serial dilutions of inhibitor were added to compete against a fixed concentration (1...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/16/2009
Entry Details Article
PubMed
TargetE3 ubiquitin-protein ligase Mdm2(Human)
Schering-Plough Research Institute

LigandChemical structure of BindingDB Monomer ID 31219BDBM31219(2-phenoxybenzoyltryptophan derivative, R4C1)
Affinity DataKi:  1.00E+4nM ΔG°:  -28.3kJ/molepH: 7.4 T: 2°CAssay Description:Ki values were determined from a competition experiment in which serial dilutions of inhibitor were added to compete against a fixed concentration (1...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/16/2009
Entry Details Article
PubMed
TargetE3 ubiquitin-protein ligase Mdm2(Human)
Schering-Plough Research Institute

LigandChemical structure of BindingDB Monomer ID 31215BDBM31215(2-phenoxybenzoyltryptophan derivative, R3C1)
Affinity DataKi:  2.00E+4nM ΔG°:  -26.6kJ/molepH: 7.4 T: 2°CAssay Description:Ki values were determined from a competition experiment in which serial dilutions of inhibitor were added to compete against a fixed concentration (1...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/16/2009
Entry Details Article
PubMed