Compile Data Set for Download or QSAR
Report error Found 14 Enz. Inhib. hit(s) with all data for entry = 1948
TargetATP-dependent molecular chaperone HSP82(Baker's yeast)
Vernalis (R&D)

LigandPNGBDBM15361(CHEMBL414883 | Monorden | (4R,6R,8R,9Z,11E)-16-chl...)
Affinity DataIC50: 200nMpH: 7.4 T: 2°CAssay Description:The HSP90 ATPase activity was determined by following the procedure of malachite green assay. The assay is based on quantitation of the green complex...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/4/2007
Entry Details Article
PubMed
TargetATP-dependent molecular chaperone HSP82(Baker's yeast)
Vernalis (R&D)

LigandPNGBDBM15384(PUZ | 8-(2,5-dimethoxybenzyl)-2-fluoro-9-pent-4-yn...)
Affinity DataIC50: 4.10E+3nMpH: 7.4 T: 2°CAssay Description:The HSP90 ATPase activity was determined by following the procedure of malachite green assay. The assay is based on quantitation of the green complex...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/4/2007
Entry Details Article
PubMed
TargetATP-dependent molecular chaperone HSP82(Baker's yeast)
Vernalis (R&D)

LigandPNGBDBM15359(17AAG | Tanespimycin | GLD-36 | (4E,6Z,8S,9S,10E,1...)
Affinity DataIC50: 1.34E+4nMpH: 7.4 T: 2°CAssay Description:The HSP90 ATPase activity was determined by following the procedure of malachite green assay. The assay is based on quantitation of the green complex...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/4/2007
Entry Details Article
PubMed
TargetATP-dependent molecular chaperone HSP82(Baker's yeast)
Vernalis (R&D)

LigandPNGBDBM15383(PU0 | 9-butyl-8-[(2,5-dimethoxyphenyl)methyl]-2-fl...)
Affinity DataIC50: 1.43E+4nMpH: 7.4 T: 2°CAssay Description:The HSP90 ATPase activity was determined by following the procedure of malachite green assay. The assay is based on quantitation of the green complex...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/4/2007
Entry Details Article
PubMed
TargetATP-dependent molecular chaperone HSP82(Baker's yeast)
Vernalis (R&D)

LigandPNGBDBM15377(PU6 | CHEMBL326564 | 8-(2H-1,3-benzodioxol-5-ylmet...)
Affinity DataIC50: 1.53E+4nMpH: 7.4 T: 2°CAssay Description:The HSP90 ATPase activity was determined by following the procedure of malachite green assay. The assay is based on quantitation of the green complex...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/4/2007
Entry Details Article
PubMed
TargetATP-dependent molecular chaperone HSP82(Baker's yeast)
Vernalis (R&D)

LigandPNGBDBM15385(8-(1,3-benzodioxol-5-ylmethyl)-9-butyl-2-fluoro-9H...)
Affinity DataIC50: 1.71E+4nMpH: 7.4 T: 2°CAssay Description:The HSP90 ATPase activity was determined by following the procedure of malachite green assay. The assay is based on quantitation of the green complex...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/4/2007
Entry Details Article
PubMed
TargetATP-dependent molecular chaperone HSP82(Baker's yeast)
Vernalis (R&D)

LigandPNGBDBM15381(8-[(2-chloro-3,4,5-trimethoxyphenyl)methyl]-2-fluo...)
Affinity DataIC50: 3.00E+4nMpH: 7.4 T: 2°CAssay Description:The HSP90 ATPase activity was determined by following the procedure of malachite green assay. The assay is based on quantitation of the green complex...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/4/2007
Entry Details Article
PubMed
TargetATP-dependent molecular chaperone HSP82(Baker's yeast)
Vernalis (R&D)

LigandPNGBDBM15378(PU7 | 9-butyl-8-(2,5-dimethoxybenzyl)-9H-purin-6-a...)
Affinity DataIC50: 4.10E+4nMpH: 7.4 T: 2°CAssay Description:The HSP90 ATPase activity was determined by following the procedure of malachite green assay. The assay is based on quantitation of the green complex...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/4/2007
Entry Details Article
PubMed
TargetATP-dependent molecular chaperone HSP82(Baker's yeast)
Vernalis (R&D)

LigandPNGBDBM15382(8-[(2,5-dimethoxyphenyl)methyl]-2-fluoro-7H-purin-...)
Affinity DataIC50: 5.35E+4nMpH: 7.4 T: 2°CAssay Description:The HSP90 ATPase activity was determined by following the procedure of malachite green assay. The assay is based on quantitation of the green complex...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/4/2007
Entry Details Article
PubMed
TargetATP-dependent molecular chaperone HSP82(Baker's yeast)
Vernalis (R&D)

LigandPNGBDBM15376(CHEMBL109612 | PU5 | 9-butyl-8-(3-methoxybenzyl)-9...)
Affinity DataIC50: 7.50E+4nMpH: 7.4 T: 2°CAssay Description:The HSP90 ATPase activity was determined by following the procedure of malachite green assay. The assay is based on quantitation of the green complex...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/4/2007
Entry Details Article
PubMed
TargetATP-dependent molecular chaperone HSP82(Baker's yeast)
Vernalis (R&D)

LigandPNGBDBM15374(CHEMBL113690 | 9-butyl-8-(3,4,5-trimethoxybenzyl)-...)
Affinity DataIC50: 2.00E+5nMpH: 7.4 T: 2°CAssay Description:The HSP90 ATPase activity was determined by following the procedure of malachite green assay. The assay is based on quantitation of the green complex...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/4/2007
Entry Details Article
PubMed
TargetATP-dependent molecular chaperone HSP82(Baker's yeast)
Vernalis (R&D)

LigandPNGBDBM15375(CHEMBL112834 | 9-butyl-8-(4-methoxybenzyl)-9H-puri...)
Affinity DataIC50: 2.00E+5nMpH: 7.4 T: 2°CAssay Description:The HSP90 ATPase activity was determined by following the procedure of malachite green assay. The assay is based on quantitation of the green complex...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/4/2007
Entry Details Article
PubMed
TargetATP-dependent molecular chaperone HSP82(Baker's yeast)
Vernalis (R&D)

LigandPNGBDBM15379(CHEMBL112896 | PU8 | 9-butyl-8-[(2-chloro-3,4,5-tr...)
Affinity DataIC50: 2.00E+5nMpH: 7.4 T: 2°CAssay Description:The HSP90 ATPase activity was determined by following the procedure of malachite green assay. The assay is based on quantitation of the green complex...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/4/2007
Entry Details Article
PubMed
TargetATP-dependent molecular chaperone HSP82(Baker's yeast)
Vernalis (R&D)

LigandPNGBDBM15380(CHEMBL326523 | PU9 | 8-[(2-chloro-3,4,5-trimethoxy...)
Affinity DataIC50: 2.00E+5nMpH: 7.4 T: 2°CAssay Description:The HSP90 ATPase activity was determined by following the procedure of malachite green assay. The assay is based on quantitation of the green complex...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/4/2007
Entry Details Article
PubMed