Compile Data Set for Download or QSAR
Report error Found 76 Enz. Inhib. hit(s) with all data for entry = 50037270
TargetAcetylcholinesterase(Mouse)
Sunesis Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50149201(3,8-Diamino-6-phenyl-5-(6-{3-[2-(1,2,3,4-tetrahydr...)
Affinity DataKd:  0.000410nMAssay Description:Dissociation constant towards Acetylcholinesterase in mouseMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/30/2012
Entry Details Article
PubMed
TargetAcetylcholinesterase(Rat)
Sunesis Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50149212(N-(1,2,3,4,8a,10a-Hexahydro-acridin-9-yl)-N'-(1,2,...)
Affinity DataIC50: 0.400nMAssay Description:Inhibitory concentration against Acetylcholinesterase in rat brainMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/30/2012
Entry Details Article
PubMed
TargetNeuraminidase(Influenza A virus (strain A/Puerto Rico/8/1934 H1N...)
Sunesis Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM4994(CHEMBL674 | (3R,4R,5S)-5-amino-4-acetamido-3-(pent...)
Affinity DataIC50: 1.30nMAssay Description:Inhibition of influenza A viral enzyme neuraminidaseMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/30/2012
Entry Details Article
PubMed
TargetAdenosine kinase(Human)
Sunesis Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50094703(CHEMBL66089 | 5-(3-bromophenyl)-7-(6-morpholin-4-y...)
Affinity DataIC50: 1.70nMAssay Description:Inhibitory concentration against adenosine kinaseMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/30/2012
Entry Details Article
PubMed
TargetGlycogen phosphorylase, liver form(Mouse)
Sunesis Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50149207(BIS[5-CHLORO-1H-INDOL-2-YL-CARBONYL-AMINOETHYL]-ET...)
Affinity DataIC50: 6nMAssay Description:Inhibitory concentration against glycogen phosphorylaseMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/30/2012
Entry Details Article
PubMed
TargetAdenosine deaminase(Human)
Sunesis Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM22920(1-[(2R)-1-hydroxy-4-{6-[3-(1-methyl-1H-1,3-benzodi...)
Affinity DataKi:  7.70nMAssay Description:Binding affinity towards adenosine deaminaseMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/30/2012
Entry Details Article
PubMed
TargetAdenosine kinase(Human)
Sunesis Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50094704(N*5*-(1H-Indol-3-ylmethyl)-7-(6-morpholin-4-yl-pyr...)
Affinity DataIC50: 10nMAssay Description:Inhibitory concentration against adenosine kinaseMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/30/2012
Entry Details Article
PubMed
TargetCollagenase 3(Human)
Sunesis Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50149235(2-[Benzyl-(4-methoxy-benzenesulfonyl)-amino]-N-hyd...)
Affinity DataIC50: 15nMAssay Description:Inhibition of Matrix Metalloprotease-13 (MMP-13)More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/30/2012
Entry Details Article
PubMed
TargetStromelysin-1(Human)
Sunesis Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50149219(3-(3'-Cyanomethyl-biphenyl-4-yloxy)-N-hydroxy-prop...)
Affinity DataIC50: 15nMAssay Description:Inhibition of Matrix Metalloprotease-3 (MMP-3)More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/30/2012
Entry Details Article
PubMed
TargetCollagenase 3(Human)
Sunesis Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50149216(WAY-170523 | Benzofuran-2-carboxylic acid (2-{4-[b...)
Affinity DataIC50: 17nMAssay Description:Inhibition of Matrix Metalloprotease-13 (MMP-13)More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/30/2012
Entry Details Article
PubMed
TargetTyrosine-protein phosphatase non-receptor type 1(Human)
Sunesis Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM13976(CHEMBL116605 | Aminobenzoic acid analog 5)
Affinity DataKi:  18nMAssay Description:Binding affinity for Protein-tyrosine phosphatase 1BMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/30/2012
Entry Details Article
PubMed
TargetAcetylcholinesterase(Mouse)
Sunesis Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM8961(CHEMBL95 | Cognex | cid_1935 | CHEMBL1337960 | 1,2...)
Affinity DataKd:  18nMAssay Description:Dissociation constant towards Acetylcholinesterase in mouseMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/30/2012
Entry Details Article
PubMedPDB3D3D Structure (crystal)
TargetCaspase-3(Human)
Sunesis Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50149217(5-{[5-((R)-1-Carboxy-2-oxo-ethylcarbamoyl)-pyrimid...)
Affinity DataKi:  20nMAssay Description:Binding affinity against Caspase-3More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/30/2012
Entry Details Article
PubMed
TargetIntegrin alpha-L/beta-2(Human)
Sunesis Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50098760(1-(4-Acetyl-piperazin-1-yl)-3-[3-chloro-4-(1H-indo...)
Affinity DataIC50: 20nMAssay Description:Inhibition of Leukocyte function associated antigen 1 (LFA-1)More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/30/2012
Entry Details Article
PubMed
TargetTyrosine-protein phosphatase non-receptor type 1(Human)
Sunesis Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50149232(3-{5-[2-[4-carboxy(2-carboxyphenyl)carboxamido-1-n...)
Affinity DataKi:  22nMAssay Description:Binding affinity for Protein-tyrosine phosphatase 1BMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/30/2012
Entry Details Article
PubMedPDB3D3D Structure (crystal)
TargetStromelysin-1(Human)
Sunesis Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50096645(3-(4'-Cyano-biphenyl-4-yloxy)-N-hydroxy-propionami...)
Affinity DataIC50: 25nMAssay Description:Inhibition of Matrix Metalloprotease-3 (MMP-3)More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/30/2012
Entry Details Article
PubMed
TargetCyclin-dependent kinase 2(Human)
Sunesis Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM7684(4-{2-[(3Z)-5-chloro-2-oxo-2,3-dihydro-1H-indol-3-y...)
Affinity DataIC50: 30nMAssay Description:Inhibition of Cyclin-Dependent Kinase 2More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/30/2012
Entry Details Article
PubMed
TargetUrokinase-type plasminogen activator(Human)
Sunesis Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50147086(8-(PYRIMIDIN-2-YLAMINO)NAPHTHALENE-2-CARBOXIMIDAMI...)
Affinity DataKi:  30nMAssay Description:Binding affinity towards Urokinase-type plasminogen activatorMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/30/2012
Entry Details Article
PubMedPDB3D3D Structure (crystal)
TargetIntegrin alpha-L/beta-2(Human)
Sunesis Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50098770(1-(4-Acetyl-piperazin-1-yl)-3-[3-chloro-4-(2,3-dih...)
Affinity DataIC50: 40nMAssay Description:Inhibition of Leukocyte function associated antigen 1 (LFA-1)More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/30/2012
Entry Details Article
PubMed
TargetTyrosine-protein phosphatase non-receptor type 1(Human)
Sunesis Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50131555(2-(4-(2-acetamido-3-(4-(1-carboxy-N-(2-carboxyphen...)
Affinity DataKi:  42nMAssay Description:Binding affinity for Protein-tyrosine phosphatase 1BMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/30/2012
Entry Details Article
PubMed
TargetAdenylosuccinate synthetase isozyme 2(Human)
Sunesis Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50149229(5-((1R,5S,7R,8S,9R)-8,9-Dihydroxy-2,4-dioxo-7-phos...)
Affinity DataIC50: 43nMAssay Description:Inhibitory concentration against Adenylosuccinate synthetaseMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/30/2012
Entry Details Article
PubMed
TargetIntegrin alpha-L/beta-2(Human)
Sunesis Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50149226((E)-1-(4-Acetyl-piperazin-1-yl)-3-[4-(2-isopropyl-...)
Affinity DataIC50: 44nMAssay Description:Inhibition of Leukocyte function associated antigen 1 (LFA-1)More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/30/2012
Entry Details Article
PubMed
TargetStromelysin-1(Human)
Sunesis Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50149245(2-[2-(3'-Cyanomethyl-biphenyl-4-sulfonyl)-ethoxy]-...)
Affinity DataIC50: 62nMAssay Description:Inhibition of Matrix Metalloprotease-3 (MMP-3)More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/30/2012
Entry Details Article
PubMed
TargetProto-oncogene tyrosine-protein kinase Src(Human)
Sunesis Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50149222(9-Ethyl-9H-carbazole-3-carbaldehyde O-{2-[1-(3,4-d...)
Affinity DataIC50: 64nMAssay Description:Inhibition of c-Src tyrosine kinaseMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/30/2012
Entry Details Article
PubMed
TargetInterstitial collagenase(Human)
Sunesis Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50149235(2-[Benzyl-(4-methoxy-benzenesulfonyl)-amino]-N-hyd...)
Affinity DataIC50: 82nMAssay Description:Inhibition of Matrix Metalloprotease-1 (MMP-1)More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/30/2012
Entry Details Article
PubMed
TargetNeuraminidase(Influenza A virus (strain A/Puerto Rico/8/1934 H1N...)
Sunesis Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM5234((3R,4R,5S)-5-amino-4-acetamido-3-(pentan-3-ylamino...)
Affinity DataIC50: 85nMAssay Description:Inhibition of influenza A viral enzyme neuraminidaseMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/30/2012
Entry Details Article
PubMed
TargetGlycogen phosphorylase, liver form(Mouse)
Sunesis Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50065965(5-Chloro-1H-indole-2-carboxylic acid [2-((R)-dimet...)
Affinity DataIC50: 130nMAssay Description:Inhibitory concentration against glycogen phosphorylaseMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/30/2012
Entry Details Article
PubMed
TargetStromelysin-1(Human)
Sunesis Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50149230(3-(Biphenyl-4-yloxy)-N-hydroxy-propionamide | CHEM...)
Affinity DataIC50: 310nMAssay Description:Inhibition of Matrix Metalloprotease-3 (MMP-3)More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/30/2012
Entry Details Article
PubMed
TargetThymidylate synthase(Lactobacillus casei)
Sunesis Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50149206((S)-2-{4-[(R)-2-(2-Carboxy-ethylcarbamoyl)-pyrroli...)
Affinity DataKi:  330nMAssay Description:Tested for binding affinity towards thymidylate synthaseMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/30/2012
Entry Details Article
PubMed
TargetStromelysin-1(Human)
Sunesis Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50149220(2-[2-(4'-Cyano-biphenyl-4-yloxy)-ethoxy]-naphthale...)
Affinity DataIC50: 340nMAssay Description:Inhibition of Matrix Metalloprotease-3 (MMP-3)More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/30/2012
Entry Details Article
PubMed
TargetUrokinase-type plasminogen activator(Human)
Sunesis Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50149214(N8-(pyrimidin-2-yl)quinoline-2,8-diamine | N*8*-Py...)
Affinity DataKi:  370nMAssay Description:Binding affinity towards Urokinase-type plasminogen activatorMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/30/2012
Entry Details Article
PubMed
TargetAcetylcholinesterase(Rat)
Sunesis Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50149204(N-Phenyl-N'-(1,2,3,4-tetrahydro-acridin-9-yl)-hept...)
Affinity DataIC50: 390nMAssay Description:Inhibitory concentration against Acetylcholinesterase in rat brainMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/30/2012
Entry Details Article
PubMed
TargetAcetylcholinesterase(Rat)
Sunesis Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM8961(CHEMBL95 | Cognex | cid_1935 | CHEMBL1337960 | 1,2...)
Affinity DataIC50: 590nMAssay Description:Inhibitory concentration against Acetylcholinesterase in rat brainMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/30/2012
Entry Details Article
PubMedPDB3D3D Structure (crystal)
TargetAdenylosuccinate synthetase isozyme 2(Human)
Sunesis Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50149203(HYDANTOCIDIN-5'-PHOSPHATE | Phosphoric acid mono-(...)
Affinity DataIC50: 675nMAssay Description:Inhibitory concentration against Adenylosuccinate synthetaseMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/30/2012
Entry Details Article
PubMed
TargetAdenosine deaminase(Human)
Sunesis Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM22919(CHEMBL327830 | imidazole-4-carboxamide derivative,...)
Affinity DataKi:  680nMAssay Description:Binding affinity towards adenosine deaminaseMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/30/2012
Entry Details Article
PubMedPDB3D3D Structure (crystal)
TargetMitogen-activated protein kinase 10(Human)
Sunesis Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50149239(2,4-Dioxo-6-phenylamino-1,2,3,4-tetrahydro-pyrimid...)
Affinity DataKi:  720nMAssay Description:Affinity for c-Jun N-terminal kinase 3More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/30/2012
Entry Details Article
PubMed
TargetTyrosine-protein phosphatase non-receptor type 1(Human)
Sunesis Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM13953(2-({4-[2-acetamido-2-(pentylcarbamoyl)ethyl]naphth...)
Affinity DataKi:  1.10E+3nMAssay Description:Binding affinity for Protein-tyrosine phosphatase 1BMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/30/2012
Entry Details Article
PubMedPDB3D3D Structure (crystal)
TargetAcetylcholinesterase(Mouse)
Sunesis Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM31904(Propidium Iodide, 2 | CHEMBL345124 | Propidium | p...)
Affinity DataKd:  1.10E+3nMAssay Description:Dissociation constant towards Acetylcholinesterase in mouseMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/30/2012
Entry Details Article
PubMed
TargetTyrosine-protein phosphatase non-receptor type 1(Human)
Sunesis Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM13971(2-({4-[2-acetamido-2-(pentylcarbamoyl)ethyl]-2-eth...)
Affinity DataKi:  1.20E+3nMAssay Description:Binding affinity for Protein-tyrosine phosphatase 1BMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/30/2012
Entry Details Article
PubMed
TargetAdenosine deaminase(Human)
Sunesis Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50149224(N-(4-{5-[(1H-Indol-2-ylamino)-methyl]-thiophen-2-y...)
Affinity DataKi:  1.20E+3nMAssay Description:Binding affinity towards adenosine deaminaseMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/30/2012
Entry Details Article
PubMed
TargetNeuraminidase(Influenza A virus (strain A/Puerto Rico/8/1934 H1N...)
Sunesis Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50149227((3R,4R,5S)-4-Acetylamino-5-amino-3-(3-phenyl-propy...)
Affinity DataIC50: 1.64E+3nMAssay Description:Inhibition of influenza A viral enzyme neuraminidaseMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/30/2012
Entry Details Article
PubMed
TargetCaspase-3(Human)
Sunesis Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50149205(5-[5-((R)-1-Carboxy-2-oxo-ethylcarbamoyl)-pentylsu...)
Affinity DataKi:  2.80E+3nMAssay Description:Binding affinity against Caspase-3More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/30/2012
Entry Details Article
PubMed
TargetAdenylosuccinate synthetase isozyme 2(Human)
Sunesis Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50149248((Formyl-hydroxy-amino)-acetic acid | HADACIDIN | C...)
Affinity DataIC50: 3.50E+3nMAssay Description:Inhibitory concentration against Adenylosuccinate synthetaseMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/30/2012
Entry Details Article
PubMed
TargetTyrosine-protein phosphatase non-receptor type 1(Human)
Sunesis Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM13990(CHEMBL117869 | 5-{2-fluoro-5-[(1E)-3-[3-hydroxy-2-...)
Affinity DataKi:  6.90E+3nMAssay Description:Binding affinity for Protein-tyrosine phosphatase 1BMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/30/2012
Entry Details Article
PubMed
TargetBcl-2-like protein 1(Human)
Sunesis Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50149242({(E)-4-(4-Chloro-phenyl)-4-[4-(3-{4-[(Z)-1-(4-chlo...)
Affinity DataIC50: 1.00E+4nMAssay Description:Inhibitory concentration against B-Cell Lymphoma xL (Bcl-xL) Bak-peptide binding regionMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/30/2012
Entry Details Article
PubMed
TargetInterstitial collagenase(Human)
Sunesis Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50149234(N-(4-morpholinobutyl)benzofuran-2-carboxamide | Be...)
Affinity DataIC50: 1.00E+4nMAssay Description:Inhibition of Matrix Metalloprotease-1 (MMP-1)More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/30/2012
Entry Details Article
PubMed
TargetCollagenase 3(Human)
Sunesis Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50149234(N-(4-morpholinobutyl)benzofuran-2-carboxamide | Be...)
Affinity DataIC50: 1.00E+4nMAssay Description:Inhibition of Matrix Metalloprotease-13 (MMP-13)More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/30/2012
Entry Details Article
PubMed
TargetInterstitial collagenase(Human)
Sunesis Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50149216(WAY-170523 | Benzofuran-2-carboxylic acid (2-{4-[b...)
Affinity DataIC50: 1.00E+4nMAssay Description:Inhibition of Matrix Metalloprotease-1 (MMP-1)More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/30/2012
Entry Details Article
PubMed
TargetGlycogen phosphorylase, liver form(Mouse)
Sunesis Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50149237(CHEMBL325455 | CP-305,494 | 5-Chloro-1H-indole-2-c...)
Affinity DataIC50: 1.25E+4nMAssay Description:Inhibitory concentration against glycogen phosphorylaseMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/30/2012
Entry Details Article
PubMed
TargetMitogen-activated protein kinase 10(Human)
Sunesis Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50149200(CHEMBL117121 | cid_1483690 | 2-Pyridin-4-yl-thiazo...)
Affinity DataKi:  1.30E+4nMAssay Description:Affinity for c-Jun N-terminal kinase 3More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/30/2012
Entry Details Article
PubMed
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