Compile Data Set for Download or QSAR
Report error Found 76 Enz. Inhib. hit(s) with all data for entry = 50037270
TargetStromelysin-1(Human)
Sunesis Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50149238(p-biphenylol | p-hydroxybiphenyl | p-hydroxydiphen...)
Affinity DataKd:  2.80E+5nMAssay Description:Dissociation constant for Matrix Metalloprotease-3 (MMP-3)More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/30/2012
Entry Details Article
PubMed
TargetAdenosine kinase(Human)
Sunesis Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50094702(CHEMBL15844 | indole | Indole, 7 | Indol | 1H-indo...)
Affinity DataKd:  3.00E+6nMAssay Description:Dissociation constant against adenosine kinaseMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/30/2012
Entry Details Article
PubMed
TargetTyrosine-protein phosphatase non-receptor type 1(Human)
Sunesis Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50149218(Benzo[b]thiophene-2-carboxylic acid | CHEMBL312607)
Affinity DataKd: >1.00E+6nMAssay Description:Dissociation constant for Protein-tyrosine phosphatase 1BMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/30/2012
Entry Details Article
PubMed
TargetStromelysin-1(Human)
Sunesis Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50015152(CHEMBL115468 | Naphthalene-1-carboxylic acid hydro...)
Affinity DataKd:  5.00E+4nMAssay Description:Dissociation constant for Matrix Metalloprotease-3 (MMP-3)More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/30/2012
Entry Details Article
PubMed
TargetStromelysin-1(Human)
Sunesis Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50121943(4'-Hydroxy-biphenyl-4-carbonitrile | CHEMBL114523)
Affinity DataKd:  2.00E+4nMAssay Description:Dissociation constant for Matrix Metalloprotease-3 (MMP-3)More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/30/2012
Entry Details Article
PubMed
TargetAcetylcholinesterase(Mouse)
Sunesis Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM31904(Propidium Iodide, 2 | CHEMBL345124 | Propidium | p...)
Affinity DataKd:  1.10E+3nMAssay Description:Dissociation constant towards Acetylcholinesterase in mouseMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/30/2012
Entry Details Article
PubMed
TargetTyrosine-protein phosphatase non-receptor type 1(Human)
Sunesis Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM48319(ISONICOTINIC ACID HYDRAZIDE P-AMINOSALICYLATE SALT...)
Affinity DataKd:  1.20E+6nMAssay Description:Dissociation constant for Protein-tyrosine phosphatase 1BMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/30/2012
Entry Details Article
PubMed
TargetStromelysin-1(Human)
Sunesis Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50099857(acetohydroxamic acid | AHA | Acethydroxamsaeure | ...)
Affinity DataKd:  1.70E+7nMAssay Description:Dissociation constant for Matrix Metalloprotease-3 (MMP-3)More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/30/2012
Entry Details Article
PubMed
TargetIntegrin alpha-L/beta-2(Human)
Sunesis Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50094702(CHEMBL15844 | indole | Indole, 7 | Indol | 1H-indo...)
Affinity DataKd:  3.00E+5nMAssay Description:Dissociation constant for Leukocyte function associated antigen 1 (LFA-1)More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/30/2012
Entry Details Article
PubMed
TargetIntegrin alpha-L/beta-2(Human)
Sunesis Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50098766(2,3-Dihydro-benzo[1,4]dioxine | CHEMBL19452)
Affinity DataKd:  1.00E+7nMAssay Description:Dissociation constant for Leukocyte function associated antigen 1 (LFA-1)More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/30/2012
Entry Details Article
PubMed
TargetAcetylcholinesterase(Mouse)
Sunesis Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50149201(3,8-Diamino-6-phenyl-5-(6-{3-[2-(1,2,3,4-tetrahydr...)
Affinity DataKd:  0.000410nMAssay Description:Dissociation constant towards Acetylcholinesterase in mouseMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/30/2012
Entry Details Article
PubMed
TargetTyrosine-protein phosphatase non-receptor type 1(Human)
Sunesis Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM13952(2-(Naphthalen-1-yloxalylamino)benzoic Acid | 2-(na...)
Affinity DataKd:  2.60E+4nMAssay Description:Dissociation constant for Protein-tyrosine phosphatase 1BMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/30/2012
Entry Details Article
PubMedPDB3D3D Structure (crystal)
TargetAcetylcholinesterase(Mouse)
Sunesis Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM8961(CHEMBL95 | Cognex | cid_1935 | CHEMBL1337960 | 1,2...)
Affinity DataKd:  18nMAssay Description:Dissociation constant towards Acetylcholinesterase in mouseMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/30/2012
Entry Details Article
PubMedPDB3D3D Structure (crystal)
TargetTyrosine-protein phosphatase non-receptor type 1(Human)
Sunesis Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM13951(CHEMBL65459 | 2-[(2,3-dimethylphenyl)amidoformic a...)
Affinity DataKd:  1.00E+5nMAssay Description:Dissociation constant for Protein-tyrosine phosphatase 1BMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/30/2012
Entry Details Article
PubMed
TargetStromelysin-1(Human)
Sunesis Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50149241((4'-Hydroxy-biphenyl-3-yl)-acetonitrile | CHEMBL11...)
Affinity DataKd:  2.00E+4nMAssay Description:Dissociation constant for Matrix Metalloprotease-3 (MMP-3)More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/30/2012
Entry Details Article
PubMed
TargetTyrosine-protein phosphatase non-receptor type 1(Human)
Sunesis Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50133281(5-(4-Bromo-phenyl)-isoxazole-3-carboxylic acid | C...)
Affinity DataKd:  8.00E+5nMAssay Description:Dissociation constant for Protein-tyrosine phosphatase 1BMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/30/2012
Entry Details Article
PubMed
TargetAcetylcholinesterase(Rat)
Sunesis Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50149212(N-(1,2,3,4,8a,10a-Hexahydro-acridin-9-yl)-N'-(1,2,...)
Affinity DataIC50: 0.400nMAssay Description:Inhibitory concentration against Acetylcholinesterase in rat brainMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/30/2012
Entry Details Article
PubMed
TargetNeuraminidase(Influenza A virus (strain A/Puerto Rico/8/1934 H1N...)
Sunesis Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM4994(CHEMBL674 | (3R,4R,5S)-5-amino-4-acetamido-3-(pent...)
Affinity DataIC50: 1.30nMAssay Description:Inhibition of influenza A viral enzyme neuraminidaseMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/30/2012
Entry Details Article
PubMed
TargetAdenosine kinase(Human)
Sunesis Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50094703(CHEMBL66089 | 5-(3-bromophenyl)-7-(6-morpholin-4-y...)
Affinity DataIC50: 1.70nMAssay Description:Inhibitory concentration against adenosine kinaseMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/30/2012
Entry Details Article
PubMed
TargetGlycogen phosphorylase, liver form(Mouse)
Sunesis Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50149207(BIS[5-CHLORO-1H-INDOL-2-YL-CARBONYL-AMINOETHYL]-ET...)
Affinity DataIC50: 6nMAssay Description:Inhibitory concentration against glycogen phosphorylaseMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/30/2012
Entry Details Article
PubMed
TargetAdenosine kinase(Human)
Sunesis Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50094704(N*5*-(1H-Indol-3-ylmethyl)-7-(6-morpholin-4-yl-pyr...)
Affinity DataIC50: 10nMAssay Description:Inhibitory concentration against adenosine kinaseMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/30/2012
Entry Details Article
PubMed
TargetStromelysin-1(Human)
Sunesis Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50149219(3-(3'-Cyanomethyl-biphenyl-4-yloxy)-N-hydroxy-prop...)
Affinity DataIC50: 15nMAssay Description:Inhibition of Matrix Metalloprotease-3 (MMP-3)More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/30/2012
Entry Details Article
PubMed
TargetCollagenase 3(Human)
Sunesis Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50149235(2-[Benzyl-(4-methoxy-benzenesulfonyl)-amino]-N-hyd...)
Affinity DataIC50: 15nMAssay Description:Inhibition of Matrix Metalloprotease-13 (MMP-13)More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/30/2012
Entry Details Article
PubMed
TargetCollagenase 3(Human)
Sunesis Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50149216(WAY-170523 | Benzofuran-2-carboxylic acid (2-{4-[b...)
Affinity DataIC50: 17nMAssay Description:Inhibition of Matrix Metalloprotease-13 (MMP-13)More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/30/2012
Entry Details Article
PubMed
TargetIntegrin alpha-L/beta-2(Human)
Sunesis Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50098760(1-(4-Acetyl-piperazin-1-yl)-3-[3-chloro-4-(1H-indo...)
Affinity DataIC50: 20nMAssay Description:Inhibition of Leukocyte function associated antigen 1 (LFA-1)More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/30/2012
Entry Details Article
PubMed
TargetStromelysin-1(Human)
Sunesis Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50096645(3-(4'-Cyano-biphenyl-4-yloxy)-N-hydroxy-propionami...)
Affinity DataIC50: 25nMAssay Description:Inhibition of Matrix Metalloprotease-3 (MMP-3)More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/30/2012
Entry Details Article
PubMed
TargetCyclin-dependent kinase 2(Human)
Sunesis Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM7684(4-{2-[(3Z)-5-chloro-2-oxo-2,3-dihydro-1H-indol-3-y...)
Affinity DataIC50: 30nMAssay Description:Inhibition of Cyclin-Dependent Kinase 2More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/30/2012
Entry Details Article
PubMed
TargetIntegrin alpha-L/beta-2(Human)
Sunesis Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50098770(1-(4-Acetyl-piperazin-1-yl)-3-[3-chloro-4-(2,3-dih...)
Affinity DataIC50: 40nMAssay Description:Inhibition of Leukocyte function associated antigen 1 (LFA-1)More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/30/2012
Entry Details Article
PubMed
TargetAdenylosuccinate synthetase isozyme 2(Human)
Sunesis Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50149229(5-((1R,5S,7R,8S,9R)-8,9-Dihydroxy-2,4-dioxo-7-phos...)
Affinity DataIC50: 43nMAssay Description:Inhibitory concentration against Adenylosuccinate synthetaseMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/30/2012
Entry Details Article
PubMed
TargetIntegrin alpha-L/beta-2(Human)
Sunesis Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50149226((E)-1-(4-Acetyl-piperazin-1-yl)-3-[4-(2-isopropyl-...)
Affinity DataIC50: 44nMAssay Description:Inhibition of Leukocyte function associated antigen 1 (LFA-1)More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/30/2012
Entry Details Article
PubMed
TargetStromelysin-1(Human)
Sunesis Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50149245(2-[2-(3'-Cyanomethyl-biphenyl-4-sulfonyl)-ethoxy]-...)
Affinity DataIC50: 62nMAssay Description:Inhibition of Matrix Metalloprotease-3 (MMP-3)More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/30/2012
Entry Details Article
PubMed
TargetProto-oncogene tyrosine-protein kinase Src(Human)
Sunesis Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50149222(9-Ethyl-9H-carbazole-3-carbaldehyde O-{2-[1-(3,4-d...)
Affinity DataIC50: 64nMAssay Description:Inhibition of c-Src tyrosine kinaseMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/30/2012
Entry Details Article
PubMed
TargetInterstitial collagenase(Human)
Sunesis Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50149235(2-[Benzyl-(4-methoxy-benzenesulfonyl)-amino]-N-hyd...)
Affinity DataIC50: 82nMAssay Description:Inhibition of Matrix Metalloprotease-1 (MMP-1)More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/30/2012
Entry Details Article
PubMed
TargetNeuraminidase(Influenza A virus (strain A/Puerto Rico/8/1934 H1N...)
Sunesis Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM5234((3R,4R,5S)-5-amino-4-acetamido-3-(pentan-3-ylamino...)
Affinity DataIC50: 85nMAssay Description:Inhibition of influenza A viral enzyme neuraminidaseMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/30/2012
Entry Details Article
PubMed
TargetGlycogen phosphorylase, liver form(Mouse)
Sunesis Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50065965(5-Chloro-1H-indole-2-carboxylic acid [2-((R)-dimet...)
Affinity DataIC50: 130nMAssay Description:Inhibitory concentration against glycogen phosphorylaseMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/30/2012
Entry Details Article
PubMed
TargetStromelysin-1(Human)
Sunesis Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50149230(3-(Biphenyl-4-yloxy)-N-hydroxy-propionamide | CHEM...)
Affinity DataIC50: 310nMAssay Description:Inhibition of Matrix Metalloprotease-3 (MMP-3)More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/30/2012
Entry Details Article
PubMed
TargetStromelysin-1(Human)
Sunesis Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50149220(2-[2-(4'-Cyano-biphenyl-4-yloxy)-ethoxy]-naphthale...)
Affinity DataIC50: 340nMAssay Description:Inhibition of Matrix Metalloprotease-3 (MMP-3)More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/30/2012
Entry Details Article
PubMed
TargetAcetylcholinesterase(Rat)
Sunesis Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50149204(N-Phenyl-N'-(1,2,3,4-tetrahydro-acridin-9-yl)-hept...)
Affinity DataIC50: 390nMAssay Description:Inhibitory concentration against Acetylcholinesterase in rat brainMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/30/2012
Entry Details Article
PubMed
TargetAcetylcholinesterase(Rat)
Sunesis Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM8961(CHEMBL95 | Cognex | cid_1935 | CHEMBL1337960 | 1,2...)
Affinity DataIC50: 590nMAssay Description:Inhibitory concentration against Acetylcholinesterase in rat brainMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/30/2012
Entry Details Article
PubMedPDB3D3D Structure (crystal)
TargetAdenylosuccinate synthetase isozyme 2(Human)
Sunesis Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50149203(HYDANTOCIDIN-5'-PHOSPHATE | Phosphoric acid mono-(...)
Affinity DataIC50: 675nMAssay Description:Inhibitory concentration against Adenylosuccinate synthetaseMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/30/2012
Entry Details Article
PubMed
TargetNeuraminidase(Influenza A virus (strain A/Puerto Rico/8/1934 H1N...)
Sunesis Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50149227((3R,4R,5S)-4-Acetylamino-5-amino-3-(3-phenyl-propy...)
Affinity DataIC50: 1.64E+3nMAssay Description:Inhibition of influenza A viral enzyme neuraminidaseMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/30/2012
Entry Details Article
PubMed
TargetAdenylosuccinate synthetase isozyme 2(Human)
Sunesis Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50149248((Formyl-hydroxy-amino)-acetic acid | HADACIDIN | C...)
Affinity DataIC50: 3.50E+3nMAssay Description:Inhibitory concentration against Adenylosuccinate synthetaseMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/30/2012
Entry Details Article
PubMed
TargetBcl-2-like protein 1(Human)
Sunesis Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50149242({(E)-4-(4-Chloro-phenyl)-4-[4-(3-{4-[(Z)-1-(4-chlo...)
Affinity DataIC50: 1.00E+4nMAssay Description:Inhibitory concentration against B-Cell Lymphoma xL (Bcl-xL) Bak-peptide binding regionMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/30/2012
Entry Details Article
PubMed
TargetInterstitial collagenase(Human)
Sunesis Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50149234(N-(4-morpholinobutyl)benzofuran-2-carboxamide | Be...)
Affinity DataIC50: 1.00E+4nMAssay Description:Inhibition of Matrix Metalloprotease-1 (MMP-1)More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/30/2012
Entry Details Article
PubMed
TargetInterstitial collagenase(Human)
Sunesis Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50149216(WAY-170523 | Benzofuran-2-carboxylic acid (2-{4-[b...)
Affinity DataIC50: 1.00E+4nMAssay Description:Inhibition of Matrix Metalloprotease-1 (MMP-1)More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/30/2012
Entry Details Article
PubMed
TargetCollagenase 3(Human)
Sunesis Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50149234(N-(4-morpholinobutyl)benzofuran-2-carboxamide | Be...)
Affinity DataIC50: 1.00E+4nMAssay Description:Inhibition of Matrix Metalloprotease-13 (MMP-13)More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/30/2012
Entry Details Article
PubMed
TargetGlycogen phosphorylase, liver form(Mouse)
Sunesis Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50149237(CHEMBL325455 | CP-305,494 | 5-Chloro-1H-indole-2-c...)
Affinity DataIC50: 1.25E+4nMAssay Description:Inhibitory concentration against glycogen phosphorylaseMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/30/2012
Entry Details Article
PubMed
TargetMatrix metalloproteinase-9(Human)
Sunesis Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50116272((2-Aminomethyl-3H-benzoimidazol-5-yl)-(2-benzyloxy...)
Affinity DataIC50: 1.30E+4nMAssay Description:Inhibition of gelatinase B, matrix metalloprotease-9 (MMP-9)More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/30/2012
Entry Details Article
PubMed
TargetNeuraminidase(Influenza A virus (strain A/Puerto Rico/8/1934 H1N...)
Sunesis Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50149228((3R,4R,5S)-4-Acetylamino-3,5-diamino-cyclohex-1-en...)
Affinity DataIC50: 3.10E+4nMAssay Description:Inhibition of influenza A viral enzyme neuraminidaseMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/30/2012
Entry Details Article
PubMed
TargetProto-oncogene tyrosine-protein kinase Src(Human)
Sunesis Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50149221(9-Ethyl-9H-carbazole-3-carbaldehyde O-methyl-oxime...)
Affinity DataIC50: 4.00E+4nMAssay Description:Inhibition of c-Src tyrosine kinaseMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/30/2012
Entry Details Article
PubMed
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