Compile Data Set for Download or QSAR
Report error Found 16 Enz. Inhib. hit(s) with all data for entry = 50014888
TargetReverse transcriptase/RNaseH(Human immunodeficiency virus type 1)
Instituto De QuíMica MéDica (Csic)

Curated by ChEMBL
LigandPNGBDBM50192289(1-[(5R,6R,8R,9R)-4-amino-9-(tert-butyl-dimethyl-si...)
Affinity DataIC50: 3.10E+3nMAssay Description:Inhibitory concentration against wild type HIV-1 reverse transcriptase (RT) using poly rC.dG as the template or primerMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetReverse transcriptase/RNaseH(Human immunodeficiency virus type 1)
Instituto De QuíMica MéDica (Csic)

Curated by ChEMBL
LigandPNGBDBM50148763([1-[2',5'-Bis-O-(tert-butyldimethylsilyl)-beta-D-r...)
Affinity DataIC50: 3.70E+3nMAssay Description:Inhibitory concentration against wild type HIV-1 reverse transcriptase (RT) using poly rC.dG as the template or primerMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetReverse transcriptase/RNaseH(Human immunodeficiency virus type 1)
Instituto De QuíMica MéDica (Csic)

Curated by ChEMBL
LigandPNGBDBM50148764([1-[2',5'-Bis-O-(tert-butyldimethylsilyl)-beta-D-r...)
Affinity DataIC50: 3.80E+3nMAssay Description:Inhibitory concentration against wild type HIV-1 reverse transcriptase (RT) using poly rC.dG as the template or primerMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetReverse transcriptase/RNaseH(Human immunodeficiency virus type 1)
Instituto De QuíMica MéDica (Csic)

Curated by ChEMBL
LigandPNGBDBM50148762([1-[2',5'-Bis-O-(tert-butyldimethylsilyl)-beta-D-r...)
Affinity DataIC50: 4.70E+3nMAssay Description:Inhibitory concentration against wild type HIV-1 reverse transcriptase (RT) using poly rC.dG as the template or primerMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetReverse transcriptase/RNaseH(Human immunodeficiency virus type 1)
Instituto De QuíMica MéDica (Csic)

Curated by ChEMBL
LigandPNGBDBM50148760([1-[2',5'-Bis-O-(tert-butyldimethylsilyl)-beta-D-r...)
Affinity DataIC50: 6.30E+3nMAssay Description:Inhibitory concentration against wild type HIV-1 reverse transcriptase (RT) using poly rC.dG as the template or primerMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetReverse transcriptase/RNaseH(Human immunodeficiency virus type 1)
Instituto De QuíMica MéDica (Csic)

Curated by ChEMBL
LigandPNGBDBM50100110(1-[4-Amino-9-(tert-butyl-dimethyl-silanyloxy)-6-(t...)
Affinity DataIC50: 8.10E+3nMAssay Description:Inhibitory concentration against wild type HIV-1 reverse transcriptase (RT) using poly rC.dG as the template or primerMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetReverse transcriptase/RNaseH(Human immunodeficiency virus type 1)
Instituto De QuíMica MéDica (Csic)

Curated by ChEMBL
LigandPNGBDBM50148761([1-[2',5'-Bis-O-(tert-butyldimethylsilyl)-beta-D-r...)
Affinity DataIC50: 1.10E+4nMAssay Description:Inhibitory concentration against wild type HIV-1 reverse transcriptase (RT) using poly rC.dG as the template or primerMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetReverse transcriptase/RNaseH(Human immunodeficiency virus type 1)
Instituto De QuíMica MéDica (Csic)

Curated by ChEMBL
LigandPNGBDBM50011181(CHEMBL666 | (PFA)dihydroxyphosphinecarboxylic acid...)
Affinity DataIC50: 2.40E+4nMAssay Description:Inhibitory concentration against wild type HIV-1 reverse transcriptase (RT) using poly rC.dG as the template or primerMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMedPDB3D3D Structure (crystal)
TargetReverse transcriptase/RNaseH(Human immunodeficiency virus type 1)
Instituto De QuíMica MéDica (Csic)

Curated by ChEMBL
LigandPNGBDBM50011181(CHEMBL666 | (PFA)dihydroxyphosphinecarboxylic acid...)
Affinity DataIC50: 5.60E+4nMAssay Description:Inhibitory concentration against wild type HIV-1/138Lys reverse transcriptase (RT) using [3H]dGTP as a radioligandMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMedPDB3D3D Structure (crystal)
TargetReverse transcriptase/RNaseH(Human immunodeficiency virus type 1)
Instituto De QuíMica MéDica (Csic)

Curated by ChEMBL
LigandPNGBDBM50100110(1-[4-Amino-9-(tert-butyl-dimethyl-silanyloxy)-6-(t...)
Affinity DataIC50: 1.00E+5nMAssay Description:Inhibitory concentration against wild type HIV-1/138Lys reverse transcriptase (RT) using [3H]dGTP as a radioligandMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetReverse transcriptase/RNaseH(Human immunodeficiency virus type 1)
Instituto De QuíMica MéDica (Csic)

Curated by ChEMBL
LigandPNGBDBM50192289(1-[(5R,6R,8R,9R)-4-amino-9-(tert-butyl-dimethyl-si...)
Affinity DataIC50: 1.00E+5nMAssay Description:Inhibitory concentration against wild type HIV-1/138Lys reverse transcriptase (RT) using [3H]dGTP as a radioligandMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetReverse transcriptase/RNaseH(Human immunodeficiency virus type 1)
Instituto De QuíMica MéDica (Csic)

Curated by ChEMBL
LigandPNGBDBM50148760([1-[2',5'-Bis-O-(tert-butyldimethylsilyl)-beta-D-r...)
Affinity DataIC50: 2.93E+5nMAssay Description:Inhibitory concentration against wild type HIV-1/138Lys reverse transcriptase (RT) using [3H]dGTP as a radioligandMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetReverse transcriptase/RNaseH(Human immunodeficiency virus type 1)
Instituto De QuíMica MéDica (Csic)

Curated by ChEMBL
LigandPNGBDBM50148764([1-[2',5'-Bis-O-(tert-butyldimethylsilyl)-beta-D-r...)
Affinity DataIC50: 3.12E+5nMAssay Description:Inhibitory concentration against wild type HIV-1/138Lys reverse transcriptase (RT) using [3H]dGTP as a radioligandMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetReverse transcriptase/RNaseH(Human immunodeficiency virus type 1)
Instituto De QuíMica MéDica (Csic)

Curated by ChEMBL
LigandPNGBDBM50148762([1-[2',5'-Bis-O-(tert-butyldimethylsilyl)-beta-D-r...)
Affinity DataIC50: 3.94E+5nMAssay Description:Inhibitory concentration against wild type HIV-1/138Lys reverse transcriptase (RT) using [3H]dGTP as a radioligandMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetReverse transcriptase/RNaseH(Human immunodeficiency virus type 1)
Instituto De QuíMica MéDica (Csic)

Curated by ChEMBL
LigandPNGBDBM50148763([1-[2',5'-Bis-O-(tert-butyldimethylsilyl)-beta-D-r...)
Affinity DataIC50: 4.37E+5nMAssay Description:Inhibitory concentration against wild type HIV-1/138Lys reverse transcriptase (RT) using [3H]dGTP as a radioligandMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetReverse transcriptase/RNaseH(Human immunodeficiency virus type 1)
Instituto De QuíMica MéDica (Csic)

Curated by ChEMBL
LigandPNGBDBM50148761([1-[2',5'-Bis-O-(tert-butyldimethylsilyl)-beta-D-r...)
Affinity DataIC50: 5.00E+5nMAssay Description:Inhibitory concentration against wild type HIV-1/138Lys reverse transcriptase (RT) using [3H]dGTP as a radioligandMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed