Compile Data Set for Download or QSAR
Report error Found 33 Enz. Inhib. hit(s) with all data for entry = 50035404
TargetMitogen-activated protein kinase 14(Mouse)
Novartis Institutes For Biomedical Research

Curated by ChEMBL
LigandPNGBDBM50148704((6-Chloro-2-methyl-3H-benzoimidazol-5-yl)-[4-(2,4-...)
Affinity DataIC50: 700nMAssay Description:Inhibition of murine His-Mitogen-activated protein kinase p38 alpha phosphorylation.More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/10/2012
Entry Details Article
PubMed
TargetMitogen-activated protein kinase 14(Mouse)
Novartis Institutes For Biomedical Research

Curated by ChEMBL
LigandPNGBDBM50148720([4-(2,4-Difluoro-phenylamino)-phenyl]-{5-[2-(4-hyd...)
Affinity DataIC50: 1.00E+3nMAssay Description:Inhibition of murine His-Mitogen-activated protein kinase p38 alpha phosphorylation.More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/10/2012
Entry Details Article
PubMed
TargetHepatocyte growth factor receptor(Human)
Novartis Institutes For Biomedical Research

Curated by ChEMBL
LigandPNGBDBM50148709((5-(3-amino-3-methylbut-1-ynyl)-2-methoxyphenyl)(4...)
Affinity DataIC50: 1.50E+3nMAssay Description:Inhibit of human Met proto-oncogene tyrosine kinaseMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/10/2012
Entry Details Article
PubMed
TargetCytochrome P450 2D6(Human)
Novartis Institutes For Biomedical Research

Curated by ChEMBL
LigandPNGBDBM50148709((5-(3-amino-3-methylbut-1-ynyl)-2-methoxyphenyl)(4...)
Affinity DataIC50: 2.00E+3nMAssay Description:Inhibition of human cytochrome P450 2D6More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/10/2012
Entry Details Article
PubMed
TargetCytochrome P450 2C9(Human)
Novartis Institutes For Biomedical Research

Curated by ChEMBL
LigandPNGBDBM50148709((5-(3-amino-3-methylbut-1-ynyl)-2-methoxyphenyl)(4...)
Affinity DataIC50: 2.00E+3nMAssay Description:Inhibition of human cytochrome P450 2C9More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/10/2012
Entry Details Article
PubMed
TargetCytochrome P450 2D6(Human)
Novartis Institutes For Biomedical Research

Curated by ChEMBL
LigandPNGBDBM50148708([4-(2,4-Difluoro-phenylamino)-phenyl]-(6-methoxy-2...)
Affinity DataIC50: 2.00E+3nMAssay Description:Inhibition of human cytochrome P450 2D6More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/10/2012
Entry Details Article
PubMed
TargetCytochrome P450 3A4(Human)
Novartis Institutes For Biomedical Research

Curated by ChEMBL
LigandPNGBDBM50148709((5-(3-amino-3-methylbut-1-ynyl)-2-methoxyphenyl)(4...)
Affinity DataIC50: 2.00E+3nMAssay Description:Inhibition of human cytochrome P450 3A4More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/10/2012
Entry Details Article
PubMed
TargetCytochrome P450 1A2(Human)
Novartis Institutes For Biomedical Research

Curated by ChEMBL
LigandPNGBDBM50148709((5-(3-amino-3-methylbut-1-ynyl)-2-methoxyphenyl)(4...)
Affinity DataIC50: 2.00E+3nMAssay Description:Inhibition of human cytochrome P450 1A2More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/10/2012
Entry Details Article
PubMed
TargetCytochrome P450 3A4(Human)
Novartis Institutes For Biomedical Research

Curated by ChEMBL
LigandPNGBDBM50148708([4-(2,4-Difluoro-phenylamino)-phenyl]-(6-methoxy-2...)
Affinity DataIC50: 2.00E+3nMAssay Description:Inhibition of human cytochrome P450 3A4More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/10/2012
Entry Details Article
PubMed
TargetCytochrome P450 1A2(Human)
Novartis Institutes For Biomedical Research

Curated by ChEMBL
LigandPNGBDBM50148708([4-(2,4-Difluoro-phenylamino)-phenyl]-(6-methoxy-2...)
Affinity DataIC50: 2.00E+3nMAssay Description:Inhibition of human cytochrome P450 1A2More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/10/2012
Entry Details Article
PubMed
TargetCytochrome P450 2C9(Human)
Novartis Institutes For Biomedical Research

Curated by ChEMBL
LigandPNGBDBM50148708([4-(2,4-Difluoro-phenylamino)-phenyl]-(6-methoxy-2...)
Affinity DataIC50: 2.00E+3nMAssay Description:Inhibition of human cytochrome P450 2C9More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/10/2012
Entry Details Article
PubMed
TargetEpidermal growth factor receptor(Human)
Novartis Institutes For Biomedical Research

Curated by ChEMBL
LigandPNGBDBM50148709((5-(3-amino-3-methylbut-1-ynyl)-2-methoxyphenyl)(4...)
Affinity DataIC50: 4.40E+3nMAssay Description:Inhibition of human Epidermal growth factor receptorMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/10/2012
Entry Details Article
PubMed
TargetMitogen-activated protein kinase 14(Mouse)
Novartis Institutes For Biomedical Research

Curated by ChEMBL
LigandPNGBDBM50148708([4-(2,4-Difluoro-phenylamino)-phenyl]-(6-methoxy-2...)
Affinity DataIC50: 5.00E+3nMAssay Description:Inhibition of murine His-Mitogen-activated protein kinase p38 alpha phosphorylation.More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/10/2012
Entry Details Article
PubMed
TargetMitogen-activated protein kinase 14(Mouse)
Novartis Institutes For Biomedical Research

Curated by ChEMBL
LigandPNGBDBM50148716([5-(3-Amino-3-methyl-but-1-ynyl)-2-chloro-phenyl]-...)
Affinity DataIC50: 6.00E+3nMAssay Description:Inhibition of murine His-Mitogen-activated protein kinase p38 alpha phosphorylation.More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/10/2012
Entry Details Article
PubMed
TargetMitogen-activated protein kinase 14(Mouse)
Novartis Institutes For Biomedical Research

Curated by ChEMBL
LigandPNGBDBM50148711([5-(3-Amino-3-methyl-but-1-ynyl)-2-methoxy-phenyl]...)
Affinity DataIC50: 8.00E+3nMAssay Description:Inhibition of murine His-Mitogen-activated protein kinase p38 alpha phosphorylation.More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/10/2012
Entry Details Article
PubMed
TargetMitogen-activated protein kinase 14(Mouse)
Novartis Institutes For Biomedical Research

Curated by ChEMBL
LigandPNGBDBM50148715((6-Chloro-2-methyl-3H-benzoimidazol-5-yl)-[6-(2,4-...)
Affinity DataIC50: 8.00E+3nMAssay Description:Inhibition of murine His-Mitogen-activated protein kinase p38 alpha phosphorylation.More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/10/2012
Entry Details Article
PubMed
TargetEpidermal growth factor receptor(Human)
Novartis Institutes For Biomedical Research

Curated by ChEMBL
LigandPNGBDBM50148709((5-(3-amino-3-methylbut-1-ynyl)-2-methoxyphenyl)(4...)
Affinity DataIC50: 8.80E+3nMAssay Description:Inhibition of human Epidermal growth factor receptorMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/10/2012
Entry Details Article
PubMed
TargetMitogen-activated protein kinase 9(Human)
Novartis Institutes For Biomedical Research

Curated by ChEMBL
LigandPNGBDBM50148709((5-(3-amino-3-methylbut-1-ynyl)-2-methoxyphenyl)(4...)
Affinity DataIC50: 1.00E+4nMAssay Description:Inhibit of human c-Jun N-terminal kinase 2More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/10/2012
Entry Details Article
PubMed
TargetMitogen-activated protein kinase 9(Human)
Novartis Institutes For Biomedical Research

Curated by ChEMBL
LigandPNGBDBM50148708([4-(2,4-Difluoro-phenylamino)-phenyl]-(6-methoxy-2...)
Affinity DataIC50: 1.00E+4nMAssay Description:Inhibit of human c-Jun N-terminal kinase 2More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/10/2012
Entry Details Article
PubMed
TargetMitogen-activated protein kinase 14(Mouse)
Novartis Institutes For Biomedical Research

Curated by ChEMBL
LigandPNGBDBM50148707((2-Chloro-phenyl)-[4-(2,4-difluoro-phenylamino)-ph...)
Affinity DataIC50: 1.10E+4nMAssay Description:Inhibition of murine His-Mitogen-activated protein kinase p38 alpha phosphorylation.More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/10/2012
Entry Details Article
PubMed
TargetMitogen-activated protein kinase 14(Mouse)
Novartis Institutes For Biomedical Research

Curated by ChEMBL
LigandPNGBDBM50148709((5-(3-amino-3-methylbut-1-ynyl)-2-methoxyphenyl)(4...)
Affinity DataIC50: 1.40E+4nMAssay Description:Inhibition of murine His-Mitogen-activated protein kinase p38 alpha phosphorylation.More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/10/2012
Entry Details Article
PubMed
TargetMitogen-activated protein kinase 14(Mouse)
Novartis Institutes For Biomedical Research

Curated by ChEMBL
LigandPNGBDBM50148706([5-(3-Amino-3-methyl-but-1-ynyl)-2-chloro-phenyl]-...)
Affinity DataIC50: 1.90E+4nMAssay Description:Inhibition of murine His-Mitogen-activated protein kinase p38 alpha phosphorylation.More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/10/2012
Entry Details Article
PubMed
TargetMitogen-activated protein kinase 14(Mouse)
Novartis Institutes For Biomedical Research

Curated by ChEMBL
LigandPNGBDBM50148705([6-(2,4-Difluoro-phenylamino)-pyridin-3-yl]-(6-met...)
Affinity DataIC50: 2.10E+4nMAssay Description:Inhibition of murine His-Mitogen-activated protein kinase p38 alpha phosphorylation.More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/10/2012
Entry Details Article
PubMed
TargetMitogen-activated protein kinase 14(Mouse)
Novartis Institutes For Biomedical Research

Curated by ChEMBL
LigandPNGBDBM50148712([4-(2,4-Difluoro-phenylamino)-phenyl]-(2-methoxy-p...)
Affinity DataIC50: 3.80E+4nMAssay Description:Inhibition of murine His-Mitogen-activated protein kinase p38 alpha phosphorylation.More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/10/2012
Entry Details Article
PubMed
TargetMitogen-activated protein kinase 14(Mouse)
Novartis Institutes For Biomedical Research

Curated by ChEMBL
LigandPNGBDBM50148718([4-(2,4-Difluoro-phenylamino)-phenyl]-{5-[2-(4-hyd...)
Affinity DataIC50: 5.10E+4nMAssay Description:Inhibition of murine His-Mitogen-activated protein kinase p38 alpha phosphorylation.More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/10/2012
Entry Details Article
PubMed
TargetMitogen-activated protein kinase 14(Mouse)
Novartis Institutes For Biomedical Research

Curated by ChEMBL
LigandPNGBDBM50148713([6-(2,4-Difluoro-phenylamino)-pyridin-3-yl]-[5-(3-...)
Affinity DataIC50: 5.40E+4nMAssay Description:Inhibition of murine His-Mitogen-activated protein kinase p38 alpha phosphorylation.More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/10/2012
Entry Details Article
PubMed
TargetProstaglandin G/H synthase 1(Human)
Novartis Institutes For Biomedical Research

Curated by ChEMBL
LigandPNGBDBM50148709((5-(3-amino-3-methylbut-1-ynyl)-2-methoxyphenyl)(4...)
Affinity DataIC50: 8.00E+4nMAssay Description:Inhibition of human prostaglandin G/H synthase 1More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/10/2012
Entry Details Article
PubMed
TargetProstaglandin G/H synthase 1(Human)
Novartis Institutes For Biomedical Research

Curated by ChEMBL
LigandPNGBDBM50148708([4-(2,4-Difluoro-phenylamino)-phenyl]-(6-methoxy-2...)
Affinity DataIC50: 8.00E+4nMAssay Description:Inhibition of human prostaglandin G/H synthase 1More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/10/2012
Entry Details Article
PubMed
TargetMitogen-activated protein kinase 14(Mouse)
Novartis Institutes For Biomedical Research

Curated by ChEMBL
LigandPNGBDBM50148717((2-Chloro-phenyl)-[6-(2,4-difluoro-phenylamino)-py...)
Affinity DataIC50: 1.01E+5nMAssay Description:Inhibition of murine His-Mitogen-activated protein kinase p38 alpha phosphorylation.More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/10/2012
Entry Details Article
PubMed
TargetMitogen-activated protein kinase 14(Mouse)
Novartis Institutes For Biomedical Research

Curated by ChEMBL
LigandPNGBDBM50148721([5-(3-Amino-3-methyl-butyl)-2-methoxy-phenyl]-[4-(...)
Affinity DataIC50: 1.13E+5nMAssay Description:Inhibition of murine His-Mitogen-activated protein kinase p38 alpha phosphorylation.More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/10/2012
Entry Details Article
PubMed
TargetMitogen-activated protein kinase 14(Mouse)
Novartis Institutes For Biomedical Research

Curated by ChEMBL
LigandPNGBDBM50148719([5-(3-Amino-3-methyl-butyl)-2-chloro-phenyl]-[6-(2...)
Affinity DataIC50: 1.60E+5nMAssay Description:Inhibition of murine His-Mitogen-activated protein kinase p38 alpha phosphorylation.More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/10/2012
Entry Details Article
PubMed
TargetMitogen-activated protein kinase 14(Mouse)
Novartis Institutes For Biomedical Research

Curated by ChEMBL
LigandPNGBDBM50148710((5-Bromo-2-chloro-phenyl)-[6-(2,4-difluoro-phenyla...)
Affinity DataIC50: 3.00E+5nMAssay Description:Inhibition of murine His-Mitogen-activated protein kinase p38 alpha phosphorylation.More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/10/2012
Entry Details Article
PubMed
TargetMitogen-activated protein kinase 14(Mouse)
Novartis Institutes For Biomedical Research

Curated by ChEMBL
LigandPNGBDBM50148714([6-(2,4-Difluoro-phenylamino)-pyridin-3-yl]-[5-(3-...)
Affinity DataIC50: 4.79E+5nMAssay Description:Inhibition of murine His-Mitogen-activated protein kinase p38 alpha phosphorylation.More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/10/2012
Entry Details Article
PubMed