Compile Data Set for Download or QSAR
Report error Found 6 Enz. Inhib. hit(s) with all data for entry = 50014787
TargetDNA topoisomerase 2-alpha(Human)
University of Maryland

Curated by ChEMBL
LigandPNGBDBM50147398(2-[2,4']Bibenzooxazolyl-2'-yl-phenol | CHEMBL32395...)
Affinity DataIC50: 2.00E+4nMAssay Description:Inhibitory activity of compound against human DNA topoisomerase II, alpha was evaluated by ability to interfere with the relaxation of supercoiled pl...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetDNA topoisomerase 2-alpha(Human)
University of Maryland

Curated by ChEMBL
LigandPNGBDBM50147398(2-[2,4']Bibenzooxazolyl-2'-yl-phenol | CHEMBL32395...)
Affinity DataIC50: 2.00E+4nMAssay Description:Inhibitory activity of compound against human DNA topoisomerase II, alpha was evaluated by ability to interfere with the relaxation of supercoiled pl...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetDNA topoisomerase 2-alpha(Human)
University of Maryland

Curated by ChEMBL
LigandPNGBDBM50147399(methyl 2-(2-(2-hydroxyphenyl)benzo[d]oxazol-4-yl)b...)
Affinity DataIC50: 3.20E+4nMAssay Description:Inhibitory activity of compound against human DNA topoisomerase II, alpha was evaluated by ability to interfere with the relaxation of supercoiled pl...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetDNA topoisomerase 2-alpha(Human)
University of Maryland

Curated by ChEMBL
LigandPNGBDBM50147400(2'-Phenyl-[2,4']bibenzooxazolyl-4-carboxylic acid ...)
Affinity DataIC50: 3.80E+4nMAssay Description:Inhibitory activity of compound against human DNA topoisomerase II, alpha was evaluated by ability to interfere with the relaxation of supercoiled pl...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetDNA topoisomerase 2-alpha(Human)
University of Maryland

Curated by ChEMBL
LigandPNGBDBM50147399(methyl 2-(2-(2-hydroxyphenyl)benzo[d]oxazol-4-yl)b...)
Affinity DataIC50: 5.00E+4nMAssay Description:Inhibitory concentration against human DNA topoisomerase II, alpha mediated relaxation of pBR322More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetDNA topoisomerase 2-alpha(Human)
University of Maryland

Curated by ChEMBL
LigandPNGBDBM50147401(2'-Phenyl-[2,4']bibenzooxazolyl | CHEMBL113081)
Affinity DataIC50: 1.00E+5nMAssay Description:Inhibitory concentration against human DNA topoisomerase II, alpha mediated relaxation of pBR322; no measurable activityMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed