Compile Data Set for Download or QSAR
Report error Found 17 Enz. Inhib. hit(s) with all data for entry = 50037317
TargetInterstitial collagenase(Human)
De Novo Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50146634(N*1*-(2,2-Dimethyl-1-methylcarbamoyl-propyl)-N*4*-...)
Affinity DataIC50: 1.30nMAssay Description:Inhibition of human matrix metalloprotease-1More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/30/2012
Entry Details Article
PubMed
TargetInterstitial collagenase(Human)
De Novo Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50146639(1-[4-(2,4-Dimethyl-benzyloxy)-benzenesulfonyl]-3-h...)
Affinity DataIC50: 10nMAssay Description:Inhibition of human matrix metalloprotease-1More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/30/2012
Entry Details Article
PubMed
TargetInterstitial collagenase(Human)
De Novo Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50071839(4-benzoyl-N-hydroxy-1-(4-phenoxyphenylsulfonyl)-1,...)
Affinity DataIC50: 22nMAssay Description:Inhibition of human matrix metalloprotease-1More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/30/2012
Entry Details Article
PubMed
TargetInterstitial collagenase(Human)
De Novo Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM8465(CGS 27023 | CHEMBL514138 | hydroxamate analogue 1 ...)
Affinity DataIC50: 27nMAssay Description:Inhibition of human matrix metalloprotease-1More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/30/2012
Entry Details Article
PubMed
TargetInterstitial collagenase(Human)
De Novo Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50146631([[1-[N-HYDROXY-ACETAMIDYL]-3-METHYL-BUTYL]-CARBONY...)
Affinity DataIC50: 40nMAssay Description:Inhibition of human matrix metalloprotease-1More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/30/2012
Entry Details Article
PubMed
TargetInterstitial collagenase(Human)
De Novo Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50146638(3-[[4-(4-Fluoro-phenoxy)-benzenesulfonyl]-(1-hydro...)
Affinity DataIC50: 90nMAssay Description:Inhibition of human matrix metalloprotease-1More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/30/2012
Entry Details Article
PubMed
TargetInterstitial collagenase(Human)
De Novo Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50146628(2-(4-But-2-ynyloxy-benzenesulfonyl)-1,2,3,4-tetrah...)
Affinity DataIC50: 121nMAssay Description:Inhibition of human matrix metalloprotease-1More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/30/2012
Entry Details Article
PubMed
TargetInterstitial collagenase(Human)
De Novo Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50146632(2-[(4-Buta-2,3-dienyloxy-benzenesulfonyl)-methyl-a...)
Affinity DataIC50: 138nMAssay Description:Inhibition of human matrix metalloprotease-1More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/30/2012
Entry Details Article
PubMed
TargetInterstitial collagenase(Human)
De Novo Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50146640(2-[4-(5-Chloro-pyridin-2-yloxy)-piperidine-1-sulfo...)
Affinity DataIC50: 360nMAssay Description:Inhibition of human matrix metalloprotease-1More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/30/2012
Entry Details Article
PubMed
TargetInterstitial collagenase(Human)
De Novo Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50146637(1-(4-Butoxy-benzenesulfonyl)-4-morpholin-4-yl-pyrr...)
Affinity DataIC50: 920nMAssay Description:Inhibition of human matrix metalloprotease-1More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/30/2012
Entry Details Article
PubMed
TargetInterstitial collagenase(Human)
De Novo Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50146629(N-Hydroxy-2-[(4-nitro-benzyl)-(4-trifluoromethyl-b...)
Affinity DataKi:  3nMAssay Description:Inhibition of human matrix metalloprotease-1More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/30/2012
Entry Details Article
PubMed
TargetInterstitial collagenase(Human)
De Novo Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50088118(N-Hydroxy-2-[(4-nitro-benzyl)-pentafluorobenzenesu...)
Affinity DataKi:  5nMAssay Description:Inhibition of human matrix metalloprotease-1More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/30/2012
Entry Details Article
PubMed
TargetInterstitial collagenase(Human)
De Novo Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50082556(AG-3340 | 2,2-Dimethyl-4-[4-(pyridin-4-yloxy)-benz...)
Affinity DataKi:  8.20nMAssay Description:Inhibition of human matrix metalloprotease-1More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/30/2012
Entry Details Article
PubMed
TargetInterstitial collagenase(Human)
De Novo Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM8465(CGS 27023 | CHEMBL514138 | hydroxamate analogue 1 ...)
Affinity DataKi:  33nMAssay Description:Inhibition of human matrix metalloprotease-1More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/30/2012
Entry Details Article
PubMed
TargetInterstitial collagenase(Human)
De Novo Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50146636(2-{4-[4-(4-CHLORO-PHENOXY)-BENZENESULFONYL]-TETRAH...)
Affinity DataKi:  70nMAssay Description:Inhibition of human matrix metalloprotease-1More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/30/2012
Entry Details Article
PubMed
TargetInterstitial collagenase(Human)
De Novo Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50146633(1-[4-(4-Imidazol-1-yl-phenoxy)-piperidine-1-sulfon...)
Affinity DataKi:  224nMAssay Description:Inhibition of human matrix metalloprotease-1More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/30/2012
Entry Details Article
PubMed
TargetInterstitial collagenase(Human)
De Novo Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50146635(1-(4-Pyridin-2-yl-piperazine-1-sulfonyl)-piperidin...)
Affinity DataKi:  423nMAssay Description:Inhibition of human matrix metalloprotease-1More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/30/2012
Entry Details Article
PubMed