Compile Data Set for Download or QSAR
Report error Found 44 Enz. Inhib. hit(s) with all data for entry = 50014694
TargetRetinoic acid receptor RXR-alpha(Human)
Eli Lilly

Curated by ChEMBL
LigandPNGBDBM50146338((E)-3-[3-(2-Ethoxy-3,5-diisopropyl-phenyl)-thieno[...)
Affinity DataEC50:  1.44E+3nMAssay Description:Effective concentration for antagonistic activity against RXR-alpha expressed in CV-1 cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetRetinoic acid receptor RXR-alpha(Human)
Eli Lilly

Curated by ChEMBL
LigandPNGBDBM50146333((E)-3-[4-(2-Butoxy-3,5-diisopropyl-phenyl)-1H-indo...)
Affinity DataEC50:  3.98E+3nMAssay Description:Effective concentration for antagonistic activity against RXR-alpha expressed in CV-1 cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetRetinoic acid receptor RXR-alpha(Human)
Eli Lilly

Curated by ChEMBL
LigandPNGBDBM50129725(7-(2-Butoxy-3,5-diisopropyl-phenyl)-3-methyl-octa-...)
Affinity DataEC50:  4nMAssay Description:Effective concentration for antagonistic activity against RXR-alpha expressed in CV-1 cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetRetinoic acid receptor RXR-alpha(Human)
Eli Lilly

Curated by ChEMBL
LigandPNGBDBM50146328((2E,4E,6Z)-7-[3,5-Di-tert-butyl-2-(3-fluoro-propox...)
Affinity DataEC50:  6.40nMAssay Description:Effective concentration for antagonistic activity against RXR-alpha expressed in CV-1 cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetRetinoic acid receptor RXR-alpha(Human)
Eli Lilly

Curated by ChEMBL
LigandPNGBDBM50146330((E)-3-[3-(3,5-Diisopropyl-2-methoxy-phenyl)-benzo[...)
Affinity DataEC50:  914nMAssay Description:Effective concentration required for agonistic activity in CV-1 cells expressing RXR-alphaMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetRetinoic acid receptor RXR-alpha(Human)
Eli Lilly

Curated by ChEMBL
LigandPNGBDBM50146331((E)-3-{3-[3,5-Di-tert-butyl-2-(2,2-difluoro-ethoxy...)
Affinity DataEC50:  65nMAssay Description:Effective concentration required for agonistic activity in CV-1 cells expressing RXR-alphaMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetRetinoic acid receptor RXR-alpha(Human)
Eli Lilly

Curated by ChEMBL
LigandPNGBDBM50146335((E)-3-{3-[2-(3-Fluoro-propoxy)-3,5-diisopropyl-phe...)
Affinity DataEC50:  4.15E+3nMAssay Description:Effective concentration for antagonistic activity against RXR-alpha expressed in CV-1 cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetRetinoic acid receptor RXR-alpha(Human)
Eli Lilly

Curated by ChEMBL
LigandPNGBDBM50146325((E)-3-[3-(2-Hydroxy-3,5-diisopropyl-phenyl)-benzo[...)
Affinity DataEC50:  1.44E+3nMAssay Description:Effective concentration required for agonistic activity in CV-1 cells expressing RXR-alphaMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetRetinoic acid receptor RXR-alpha(Human)
Eli Lilly

Curated by ChEMBL
LigandPNGBDBM50129726((2E,4E,6Z)-7-(2-Ethoxy-3,5-diisopropyl-phenyl)-3-m...)
Affinity DataEC50:  2nMAssay Description:Effective concentration required for agonistic activity in CV-1 cells expressing RXR-alphaMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetRetinoic acid receptor RXR-alpha(Human)
Eli Lilly

Curated by ChEMBL
LigandPNGBDBM50146337((E)-3-[3-(2-Butoxy-3,5-di-tert-butyl-phenyl)-1H-in...)
Affinity DataEC50:  26nMAssay Description:Effective concentration for antagonistic activity against RXR-alpha expressed in CV-1 cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetRetinoic acid receptor RXR-alpha(Human)
Eli Lilly

Curated by ChEMBL
LigandPNGBDBM50146326((E)-3-[3-(2-Ethoxy-3,5-diisopropyl-phenyl)-1H-inda...)
Affinity DataEC50:  235nMAssay Description:Effective concentration for antagonistic activity against RXR-alpha expressed in CV-1 cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetRetinoic acid receptor RXR-alpha(Human)
Eli Lilly

Curated by ChEMBL
LigandPNGBDBM50146334((E)-3-[3-(2-Butoxy-3,5-diisopropyl-phenyl)-1H-indo...)
Affinity DataEC50:  21nMAssay Description:Effective concentration for antagonistic activity against RXR-alpha expressed in CV-1 cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetRetinoic acid receptor RXR-alpha(Human)
Eli Lilly

Curated by ChEMBL
LigandPNGBDBM50146331((E)-3-{3-[3,5-Di-tert-butyl-2-(2,2-difluoro-ethoxy...)
Affinity DataEC50:  66nMAssay Description:Effective concentration for antagonistic activity against RXR-alpha expressed in CV-1 cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetRetinoic acid receptor RXR-alpha(Human)
Eli Lilly

Curated by ChEMBL
LigandPNGBDBM50146329((E)-3-[3-(2-Ethoxy-3,5-diisopropyl-phenyl)-benzo[d...)
Affinity DataEC50:  1.02E+3nMAssay Description:Effective concentration for antagonistic activity against RXR-alpha expressed in CV-1 cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetRetinoic acid receptor RXR-alpha(Human)
Eli Lilly

Curated by ChEMBL
LigandPNGBDBM50146332((E)-3-[3-(2-Butoxy-3,5-diisopropyl-phenyl)-1-methy...)
Affinity DataEC50:  1.53E+3nMAssay Description:Effective concentration for antagonistic activity against RXR-alpha expressed in CV-1 cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetRetinoic acid receptor RXR-alpha(Human)
Eli Lilly

Curated by ChEMBL
LigandPNGBDBM50146327((E)-3-[3-(3,5-Di-tert-butyl-2-propoxy-phenyl)-1H-i...)
Affinity DataEC50:  30nMAssay Description:Effective concentration for antagonistic activity against RXR-alpha expressed in CV-1 cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetRetinoic acid receptor RXR-alpha(Human)
Eli Lilly

Curated by ChEMBL
LigandPNGBDBM50146327((E)-3-[3-(3,5-Di-tert-butyl-2-propoxy-phenyl)-1H-i...)
Affinity DataKi:  1.60nMAssay Description:Ability to displace [3H]9-cis-RA from Retinoid X receptor alpha in CV-1 cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetRetinoic acid receptor RXR-alpha(Human)
Eli Lilly

Curated by ChEMBL
LigandPNGBDBM50146331((E)-3-{3-[3,5-Di-tert-butyl-2-(2,2-difluoro-ethoxy...)
Affinity DataKi:  1.60nMAssay Description:Ability to displace [3H]9-cis-RA from Retinoid X receptor alpha in CV-1 cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetRetinoic acid receptor RXR-alpha(Human)
Eli Lilly

Curated by ChEMBL
LigandPNGBDBM50129726((2E,4E,6Z)-7-(2-Ethoxy-3,5-diisopropyl-phenyl)-3-m...)
Affinity DataKi:  2nMAssay Description:Ability to displace [3H]9-cis-RA from Retinoid X receptor alpha in CV-1 cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetRetinoic acid receptor RXR-alpha(Human)
Eli Lilly

Curated by ChEMBL
LigandPNGBDBM50146328((2E,4E,6Z)-7-[3,5-Di-tert-butyl-2-(3-fluoro-propox...)
Affinity DataKi:  2.70nMAssay Description:Ability to displace [3H]9-cis-RA from Retinoid X receptor alpha in CV-1 cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetRetinoic acid receptor RXR-alpha(Human)
Eli Lilly

Curated by ChEMBL
LigandPNGBDBM50146337((E)-3-[3-(2-Butoxy-3,5-di-tert-butyl-phenyl)-1H-in...)
Affinity DataKi:  3.20nMAssay Description:Ability to displace [3H]9-cis-RA from Retinoid X receptor alpha in CV-1 cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetRetinoic acid receptor RXR-alpha(Human)
Eli Lilly

Curated by ChEMBL
LigandPNGBDBM50129725(7-(2-Butoxy-3,5-diisopropyl-phenyl)-3-methyl-octa-...)
Affinity DataKi:  4nMAssay Description:Ability to displace [3H]9-cis-RA from Retinoid X receptor alpha in CV-1 cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetRetinoic acid receptor RXR-alpha(Human)
Eli Lilly

Curated by ChEMBL
LigandPNGBDBM50146334((E)-3-[3-(2-Butoxy-3,5-diisopropyl-phenyl)-1H-indo...)
Affinity DataKi:  7.40nMAssay Description:Ability to displace [3H]9-cis-RA from Retinoid X receptor alpha in CV-1 cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetRetinoic acid receptor RXR-alpha(Human)
Eli Lilly

Curated by ChEMBL
LigandPNGBDBM50146330((E)-3-[3-(3,5-Diisopropyl-2-methoxy-phenyl)-benzo[...)
Affinity DataKi:  30nMAssay Description:Ability to displace [3H]9-cis-RA from Retinoid X receptor alpha in CV-1 cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetRetinoic acid receptor RXR-alpha(Human)
Eli Lilly

Curated by ChEMBL
LigandPNGBDBM50146326((E)-3-[3-(2-Ethoxy-3,5-diisopropyl-phenyl)-1H-inda...)
Affinity DataKi:  69nMAssay Description:Ability to displace [3H]9-cis-RA from Retinoid X receptor alpha in CV-1 cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetRetinoic acid receptor RXR-alpha(Human)
Eli Lilly

Curated by ChEMBL
LigandPNGBDBM50146325((E)-3-[3-(2-Hydroxy-3,5-diisopropyl-phenyl)-benzo[...)
Affinity DataKi:  131nMAssay Description:Ability to displace [3H]9-cis-RA from Retinoid X receptor alpha in CV-1 cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetRetinoic acid receptor RXR-alpha(Human)
Eli Lilly

Curated by ChEMBL
LigandPNGBDBM50146335((E)-3-{3-[2-(3-Fluoro-propoxy)-3,5-diisopropyl-phe...)
Affinity DataKi:  395nMAssay Description:Ability to displace [3H]9-cis-RA from Retinoid X receptor alpha in CV-1 cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetRetinoic acid receptor RXR-alpha(Human)
Eli Lilly

Curated by ChEMBL
LigandPNGBDBM50146329((E)-3-[3-(2-Ethoxy-3,5-diisopropyl-phenyl)-benzo[d...)
Affinity DataKi:  648nMAssay Description:Ability to displace [3H]9-cis-RA from Retinoid X receptor alpha in CV-1 cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetRetinoic acid receptor RXR-alpha(Human)
Eli Lilly

Curated by ChEMBL
LigandPNGBDBM50146332((E)-3-[3-(2-Butoxy-3,5-diisopropyl-phenyl)-1-methy...)
Affinity DataKi:  740nMAssay Description:Ability to displace [3H]9-cis-RA from Retinoid X receptor alpha in CV-1 cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetRetinoic acid receptor RXR-alpha(Human)
Eli Lilly

Curated by ChEMBL
LigandPNGBDBM50146336((E)-3-[3-(2-Ethoxy-3,5-diisopropyl-phenyl)-imidazo...)
Affinity DataKi:  2.08E+3nMAssay Description:Ability to displace [3H]9-cis-RA from Retinoid X receptor alpha in CV-1 cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetRetinoic acid receptor gamma(Human)
Eli Lilly

Curated by ChEMBL
LigandPNGBDBM50146326((E)-3-[3-(2-Ethoxy-3,5-diisopropyl-phenyl)-1H-inda...)
Affinity DataKi: >1.00E+4nMAssay Description:Ability to displace [3H]ATRA from Retinoic acid receptor gamma in CV-1 cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetRetinoic acid receptor gamma(Human)
Eli Lilly

Curated by ChEMBL
LigandPNGBDBM50146328((2E,4E,6Z)-7-[3,5-Di-tert-butyl-2-(3-fluoro-propox...)
Affinity DataKi: >1.00E+4nMAssay Description:Ability to displace [3H]ATRA from Retinoic acid receptor gamma in CV-1 cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetRetinoic acid receptor gamma(Human)
Eli Lilly

Curated by ChEMBL
LigandPNGBDBM50146337((E)-3-[3-(2-Butoxy-3,5-di-tert-butyl-phenyl)-1H-in...)
Affinity DataKi: >1.00E+4nMAssay Description:Ability to displace [3H]ATRA from Retinoic acid receptor gamma in CV-1 cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetRetinoic acid receptor gamma(Human)
Eli Lilly

Curated by ChEMBL
LigandPNGBDBM50146325((E)-3-[3-(2-Hydroxy-3,5-diisopropyl-phenyl)-benzo[...)
Affinity DataKi: >1.00E+4nMAssay Description:Ability to displace [3H]ATRA from Retinoic acid receptor gamma in CV-1 cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetRetinoic acid receptor gamma(Human)
Eli Lilly

Curated by ChEMBL
LigandPNGBDBM50129726((2E,4E,6Z)-7-(2-Ethoxy-3,5-diisopropyl-phenyl)-3-m...)
Affinity DataKi: >1.00E+4nMAssay Description:Ability to displace [3H]ATRA from Retinoic acid receptor gamma in CV-1 cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetRetinoic acid receptor gamma(Human)
Eli Lilly

Curated by ChEMBL
LigandPNGBDBM50146331((E)-3-{3-[3,5-Di-tert-butyl-2-(2,2-difluoro-ethoxy...)
Affinity DataKi: >1.00E+4nMAssay Description:Ability to displace [3H]ATRA from Retinoic acid receptor gamma in CV-1 cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetRetinoic acid receptor gamma(Human)
Eli Lilly

Curated by ChEMBL
LigandPNGBDBM50146334((E)-3-[3-(2-Butoxy-3,5-diisopropyl-phenyl)-1H-indo...)
Affinity DataKi: >1.00E+4nMAssay Description:Ability to displace [3H]ATRA from Retinoic acid receptor gamma in CV-1 cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetRetinoic acid receptor gamma(Human)
Eli Lilly

Curated by ChEMBL
LigandPNGBDBM50146332((E)-3-[3-(2-Butoxy-3,5-diisopropyl-phenyl)-1-methy...)
Affinity DataKi: >1.00E+4nMAssay Description:Ability to displace [3H]ATRA from Retinoic acid receptor gamma in CV-1 cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetRetinoic acid receptor gamma(Human)
Eli Lilly

Curated by ChEMBL
LigandPNGBDBM50129725(7-(2-Butoxy-3,5-diisopropyl-phenyl)-3-methyl-octa-...)
Affinity DataKi: >1.00E+4nMAssay Description:Ability to displace [3H]ATRA from Retinoic acid receptor gamma in CV-1 cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetRetinoic acid receptor gamma(Human)
Eli Lilly

Curated by ChEMBL
LigandPNGBDBM50146336((E)-3-[3-(2-Ethoxy-3,5-diisopropyl-phenyl)-imidazo...)
Affinity DataKi: >1.00E+4nMAssay Description:Ability to displace [3H]ATRA from Retinoic acid receptor gamma in CV-1 cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetRetinoic acid receptor gamma(Human)
Eli Lilly

Curated by ChEMBL
LigandPNGBDBM50146335((E)-3-{3-[2-(3-Fluoro-propoxy)-3,5-diisopropyl-phe...)
Affinity DataKi: >1.00E+4nMAssay Description:Ability to displace [3H]ATRA from Retinoic acid receptor gamma in CV-1 cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetRetinoic acid receptor gamma(Human)
Eli Lilly

Curated by ChEMBL
LigandPNGBDBM50146327((E)-3-[3-(3,5-Di-tert-butyl-2-propoxy-phenyl)-1H-i...)
Affinity DataKi: >1.00E+4nMAssay Description:Ability to displace [3H]ATRA from Retinoic acid receptor gamma in CV-1 cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetRetinoic acid receptor gamma(Human)
Eli Lilly

Curated by ChEMBL
LigandPNGBDBM50146329((E)-3-[3-(2-Ethoxy-3,5-diisopropyl-phenyl)-benzo[d...)
Affinity DataKi: >1.00E+4nMAssay Description:Ability to displace [3H]ATRA from Retinoic acid receptor gamma in CV-1 cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetRetinoic acid receptor gamma(Human)
Eli Lilly

Curated by ChEMBL
LigandPNGBDBM50146330((E)-3-[3-(3,5-Diisopropyl-2-methoxy-phenyl)-benzo[...)
Affinity DataKi: >1.00E+4nMAssay Description:Ability to displace [3H]ATRA from Retinoic acid receptor gamma in CV-1 cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed