Compile Data Set for Download or QSAR
Report error Found 8 Enz. Inhib. hit(s) with all data for entry = 1285
TargetCaspase-3(Human)
Merck Research Laboratories

LigandPNGBDBM10652((3S)-3-[(2S)-2-[(4S)-4-[(3S)-3-acetamido-3-formami...)
Affinity DataIC50: 0.771nMpH: 7.0 T: 2°CAssay Description:The substrate peptides terminating in AMC are processed by caspases with or without inhibitors, and the accumulation of AMC was assessed with a Cytof...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/12/2006
Entry Details Article
PubMed
TargetCaspase-3(Human)
Merck Research Laboratories

LigandPNGBDBM10654((3S)-5-(benzylsulfanyl)-3-{[(2S,11S)-11-[(3S)-3-ac...)
Affinity DataIC50: 3nMpH: 7.0 T: 2°CAssay Description:The substrate peptides terminating in AMC are processed by caspases with or without inhibitors, and the accumulation of AMC was assessed with a Cytof...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/12/2006
Entry Details Article
PubMed
TargetCaspase-3(Human)
Merck Research Laboratories

LigandPNGBDBM10653(Compound 3 | (3S)-5-{[(2-chloro-6-fluorophenyl)met...)
Affinity DataIC50: 7.95nMpH: 7.0 T: 2°CAssay Description:The substrate peptides terminating in AMC are processed by caspases with or without inhibitors, and the accumulation of AMC was assessed with a Cytof...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/12/2006
Entry Details Article
PubMed
TargetCaspase-3(Human)
Merck Research Laboratories

LigandPNGBDBM10656(Compound 6 | (3S)-3-[2-(5-tert-butyl-3-{[(4-methyl...)
Affinity DataIC50: 9.17nMpH: 7.0 T: 2°CAssay Description:The substrate peptides terminating in AMC are processed by caspases with or without inhibitors, and the accumulation of AMC was assessed with a Cytof...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/12/2006
Entry Details Article
PubMed
TargetCaspase-3(Human)
Merck Research Laboratories

LigandPNGBDBM10527(valine aspartyl ketone 29 | BROMOMETHOXYPHENYL INH...)
Affinity DataIC50: 17.7nMpH: 7.0 T: 2°CAssay Description:The substrate peptides terminating in AMC are processed by caspases with or without inhibitors, and the accumulation of AMC was assessed with a Cytof...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/12/2006
Entry Details Article
PubMed
TargetCaspase-3(Human)
Merck Research Laboratories

LigandPNGBDBM10246((4S)-4-{[(1S)-1-{[(2S)-1-carboxy-3-oxopropan-2-yl]...)
Affinity DataIC50: 43.9nMpH: 7.0 T: 2°CAssay Description:The substrate peptides terminating in AMC are processed by caspases with or without inhibitors, and the accumulation of AMC was assessed with a Cytof...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/12/2006
Entry Details Article
PubMed
TargetCaspase-3(Human)
Merck Research Laboratories

LigandPNGBDBM10658(Compound 8 | 4-(5-{[(2S)-1-carboxy-3-oxopropan-2-y...)
Affinity DataIC50: 1.74E+3nMpH: 7.0 T: 2°CAssay Description:The substrate peptides terminating in AMC are processed by caspases with or without inhibitors, and the accumulation of AMC was assessed with a Cytof...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/12/2006
Entry Details Article
PubMed
TargetCaspase-3(Human)
Merck Research Laboratories

LigandPNGBDBM10561((3S)-3-[(5-bromopyridin-3-yl)formamido]-4-oxobutan...)
Affinity DataIC50: 6.12E+3nMpH: 7.0 T: 2°CAssay Description:The substrate peptides terminating in AMC are processed by caspases with or without inhibitors, and the accumulation of AMC was assessed with a Cytof...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/12/2006
Entry Details Article
PubMed