Compile Data Set for Download or QSAR
Report error Found 30 Enz. Inhib. hit(s) with all data for entry = 50035436
TargetProgesterone receptor(Human)
Wyeth Research

Curated by ChEMBL
LigandPNGBDBM50067678(17-Acetoxy-6alpha-methylprogesterone | 17alpha-Hyd...)
Affinity DataEC50:  0.5nMAssay Description:Ability to block progesterone induced alkaline phosphatase activity in T47D human breast cancer cell lineMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/12/2012
Entry Details Article
PubMed
TargetProgesterone receptor(Human)
Wyeth Research

Curated by ChEMBL
LigandPNGBDBM50144443(5-(4,4-Dimethyl-2-oxo-1,4-dihydro-2H-benzo[d][1,3]...)
Affinity DataEC50:  130nMAssay Description:Ability to block progesterone induced alkaline phosphatase activity in T47D human breast cancer cell lineMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/12/2012
Entry Details Article
PubMed
TargetProgesterone receptor(Human)
Wyeth Research

Curated by ChEMBL
LigandPNGBDBM50144445(2-(4,4-Dimethyl-2-oxo-1,4-dihydro-2H-benzo[d][1,3]...)
Affinity DataEC50: >1.00E+3nMAssay Description:Ability to block progesterone induced alkaline phosphatase activity in T47D human breast cancer cell lineMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/12/2012
Entry Details Article
PubMed
TargetProgesterone receptor(Human)
Wyeth Research

Curated by ChEMBL
LigandPNGBDBM50144440(4,4-Dimethyl-6-(1H-pyrrol-2-yl)-1,4-dihydro-benzo[...)
Affinity DataEC50: >3.00E+3nMAssay Description:Ability to block progesterone induced alkaline phosphatase activity in T47D human breast cancer cell lineMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/12/2012
Entry Details Article
PubMed
TargetProgesterone receptor(Human)
Wyeth Research

Curated by ChEMBL
LigandPNGBDBM50144436(5'-(5-nitro-1H-2-pyrrolyl)spiro[cyclohexane-1,3'-(...)
Affinity DataEC50: >1.00E+3nMAssay Description:Agonistic activity measures the ability to induce alkaline phosphatase in T47D human breast cancer cell lineMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/12/2012
Entry Details Article
PubMed
TargetProgesterone receptor(Human)
Wyeth Research

Curated by ChEMBL
LigandPNGBDBM50144446(5-[2'-oxospiro[cyclohexane-1,3'-(2',3'-dihydro-1'H...)
Affinity DataEC50:  60nMAssay Description:Agonistic activity measures the ability to induce alkaline phosphatase in T47D human breast cancer cell lineMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/12/2012
Entry Details Article
PubMed
TargetProgesterone receptor(Human)
Wyeth Research

Curated by ChEMBL
LigandPNGBDBM50144438(5-(4,4-Dimethyl-2-oxo-1,4-dihydro-2H-benzo[d][1,3]...)
Affinity DataEC50:  1.10nMAssay Description:Agonistic activity as progesterone receptor induced alkaline phosphatase activity in T47D human breast cancer cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/12/2012
Entry Details Article
PubMed
TargetProgesterone receptor(Human)
Wyeth Research

Curated by ChEMBL
LigandPNGBDBM50144441(4-(4,4-Dimethyl-2-oxo-1,4-dihydro-2H-benzo[d][1,3]...)
Affinity DataEC50: >1.00E+3nMAssay Description:Ability to block progesterone induced alkaline phosphatase activity in T47D human breast cancer cell lineMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/12/2012
Entry Details Article
PubMed
TargetProgesterone receptor(Human)
Wyeth Research

Curated by ChEMBL
LigandPNGBDBM50144434(5-(4,4-Dimethyl-2-oxo-1,4-dihydro-2H-benzo[d][1,3]...)
Affinity DataEC50:  1.80nMAssay Description:Agonistic activity as progesterone receptor induced alkaline phosphatase activity in T47D human breast cancer cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/12/2012
Entry Details Article
PubMed
TargetProgesterone receptor(Human)
Wyeth Research

Curated by ChEMBL
LigandPNGBDBM50144435(1-methyl-5-[2'-oxospiro[cyclohexane-1,3'-(2',3'-di...)
Affinity DataEC50:  2.80nMAssay Description:Agonistic activity measures the ability to induce alkaline phosphatase in T47D human breast cancer cell lineMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/12/2012
Entry Details Article
PubMed
TargetProgesterone receptor(Human)
Wyeth Research

Curated by ChEMBL
LigandPNGBDBM50144439(2-(4,4-Dimethyl-2-oxo-1,4-dihydro-2H-benzo[d][1,3]...)
Affinity DataEC50: >1.00E+3nMAssay Description:Ability to block progesterone induced alkaline phosphatase activity in T47D human breast cancer cell lineMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/12/2012
Entry Details Article
PubMed
TargetProgesterone receptor(Human)
Wyeth Research

Curated by ChEMBL
LigandPNGBDBM50144447(5-(4,4-Dimethyl-2-oxo-1,4-dihydro-2H-benzo[d][1,3]...)
Affinity DataEC50:  2.10nMAssay Description:Agonistic activity measures the ability to induce alkaline phosphatase in T47D human breast cancer cell lineMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/12/2012
Entry Details Article
PubMed
TargetProgesterone receptor(Human)
Wyeth Research

Curated by ChEMBL
LigandPNGBDBM50144437(5-(4,4-Dimethyl-2-oxo-1,4-dihydro-2H-benzo[d][1,3]...)
Affinity DataEC50: >1.00E+3nMAssay Description:Ability to block progesterone induced alkaline phosphatase activity in T47D human breast cancer cell lineMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/12/2012
Entry Details Article
PubMed
TargetProgesterone receptor(Human)
Wyeth Research

Curated by ChEMBL
LigandPNGBDBM50144433(4-(4,4-Dimethyl-2-oxo-1,4-dihydro-2H-benzo[d][1,3]...)
Affinity DataEC50: >1.00E+3nMAssay Description:Ability to block progesterone induced alkaline phosphatase activity in T47D human breast cancer cell lineMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/12/2012
Entry Details Article
PubMed
TargetProgesterone receptor(Human)
Wyeth Research

Curated by ChEMBL
LigandPNGBDBM50121163(3-(2'-oxo-1',2'-dihydrospiro[cyclohexane-1,3'-indo...)
Affinity DataIC50: 6.60nMAssay Description:Ability to block progesterone induced alkaline phosphatase activity in T47D human breast cancer cell lineMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/12/2012
Entry Details Article
PubMed
TargetProgesterone receptor(Human)
Wyeth Research

Curated by ChEMBL
LigandPNGBDBM50118695(3-(4,4-Dimethyl-2-oxo-1,4-dihydro-2H-benzo[d][1,3]...)
Affinity DataIC50: 8nMAssay Description:Ability to block progesterone induced alkaline phosphatase activity in T47D human breast cancer cell lineMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/12/2012
Entry Details Article
PubMed
TargetProgesterone receptor(Human)
Wyeth Research

Curated by ChEMBL
LigandPNGBDBM50144449(5-(4,4-Dimethyl-2-oxo-1,4-dihydro-2H-benzo[d][1,3]...)
Affinity DataIC50: 23nMAssay Description:Ability to block progesterone induced alkaline phosphatase activity in T47D human breast cancer cell lineMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/12/2012
Entry Details Article
PubMed
TargetProgesterone receptor(Human)
Wyeth Research

Curated by ChEMBL
LigandPNGBDBM50144436(5'-(5-nitro-1H-2-pyrrolyl)spiro[cyclohexane-1,3'-(...)
Affinity DataIC50: 36nMAssay Description:Ability to block progesterone induced alkaline phosphatase activity in T47D human breast cancer cell lineMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/12/2012
Entry Details Article
PubMed
TargetProgesterone receptor(Human)
Wyeth Research

Curated by ChEMBL
LigandPNGBDBM50144433(4-(4,4-Dimethyl-2-oxo-1,4-dihydro-2H-benzo[d][1,3]...)
Affinity DataIC50: 41nMAssay Description:Ability to block progesterone induced alkaline phosphatase activity in T47D human breast cancer cell lineMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/12/2012
Entry Details Article
PubMed
TargetProgesterone receptor(Human)
Wyeth Research

Curated by ChEMBL
LigandPNGBDBM50144442(5-(4,4-Dimethyl-2-oxo-1,4-dihydro-2H-benzo[d][1,3]...)
Affinity DataIC50: 65nMAssay Description:Ability to block progesterone induced alkaline phosphatase activity in T47D human breast cancer cell lineMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/12/2012
Entry Details Article
PubMed
TargetProgesterone receptor(Human)
Wyeth Research

Curated by ChEMBL
LigandPNGBDBM50144450(4,4-Dimethyl-6-(5-nitro-1H-pyrrol-2-yl)-1,4-dihydr...)
Affinity DataIC50: 180nMAssay Description:Ability to block progesterone induced alkaline phosphatase activity in T47D human breast cancer cell lineMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/12/2012
Entry Details Article
PubMed
TargetAndrogen receptor(Human)
Wyeth Research

Curated by ChEMBL
LigandPNGBDBM50121163(3-(2'-oxo-1',2'-dihydrospiro[cyclohexane-1,3'-indo...)
Affinity DataIC50: 1.00E+3nMAssay Description:Antagonist activity for androgen receptorMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/12/2012
Entry Details Article
PubMed
TargetProgesterone receptor(Human)
Wyeth Research

Curated by ChEMBL
LigandPNGBDBM50144443(5-(4,4-Dimethyl-2-oxo-1,4-dihydro-2H-benzo[d][1,3]...)
Affinity DataIC50: 3.00E+3nMAssay Description:Ability to block progesterone induced alkaline phosphatase activity in T47D human breast cancer cell lineMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/12/2012
Entry Details Article
PubMed
TargetProgesterone receptor(Human)
Wyeth Research

Curated by ChEMBL
LigandPNGBDBM50144445(2-(4,4-Dimethyl-2-oxo-1,4-dihydro-2H-benzo[d][1,3]...)
Affinity DataIC50: 3.00E+3nMAssay Description:Ability to block progesterone induced alkaline phosphatase activity in T47D human breast cancer cell lineMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/12/2012
Entry Details Article
PubMed
TargetProgesterone receptor(Human)
Wyeth Research

Curated by ChEMBL
LigandPNGBDBM50144435(1-methyl-5-[2'-oxospiro[cyclohexane-1,3'-(2',3'-di...)
Affinity DataIC50: 3.00E+3nMAssay Description:Ability to block progesterone induced alkaline phosphatase activity in T47D human breast cancer cell lineMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/12/2012
Entry Details Article
PubMed
TargetProgesterone receptor(Human)
Wyeth Research

Curated by ChEMBL
LigandPNGBDBM50144446(5-[2'-oxospiro[cyclohexane-1,3'-(2',3'-dihydro-1'H...)
Affinity DataIC50: 3.00E+3nMAssay Description:Ability to block progesterone induced alkaline phosphatase activity in T47D human breast cancer cell lineMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/12/2012
Entry Details Article
PubMed
TargetProgesterone receptor(Human)
Wyeth Research

Curated by ChEMBL
LigandPNGBDBM50144444(4,4-Dimethyl-6-[5-(2,2,2-trifluoro-acetyl)-1H-pyrr...)
Affinity DataIC50: 3.00E+3nMAssay Description:Ability to block progesterone induced alkaline phosphatase activity in T47D human breast cancer cell lineMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/12/2012
Entry Details Article
PubMed
TargetProgesterone receptor(Human)
Wyeth Research

Curated by ChEMBL
LigandPNGBDBM50144447(5-(4,4-Dimethyl-2-oxo-1,4-dihydro-2H-benzo[d][1,3]...)
Affinity DataIC50: 3.00E+3nMAssay Description:Ability to block progesterone induced alkaline phosphatase activity in T47D human breast cancer cell lineMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/12/2012
Entry Details Article
PubMed
TargetProgesterone receptor(Human)
Wyeth Research

Curated by ChEMBL
LigandPNGBDBM50144448(5-(4,4-Dimethyl-2-oxo-1,4-dihydro-2H-benzo[d][1,3]...)
Affinity DataIC50: 3.00E+3nMAssay Description:Ability to block progesterone induced alkaline phosphatase activity in T47D human breast cancer cell lineMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/12/2012
Entry Details Article
PubMed
TargetProgesterone receptor(Human)
Wyeth Research

Curated by ChEMBL
LigandPNGBDBM50144438(5-(4,4-Dimethyl-2-oxo-1,4-dihydro-2H-benzo[d][1,3]...)
Affinity DataIC50: 3.00E+3nMAssay Description:Ability to block progesterone induced alkaline phosphatase activity in T47D human breast cancer cell lineMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/12/2012
Entry Details Article
PubMed