Compile Data Set for Download or QSAR
Report error Found 20 Enz. Inhib. hit(s) with all data for entry = 50014539
TargetCorticotropin-releasing factor receptor 1(Human)
Neurocrine Biosciences

Curated by ChEMBL
LigandPNGBDBM50144204([4-(2-Chloro-4,6-dimethoxy-phenyl)-pyrimidin-2-yl]...)
Affinity DataKi:  11nMAssay Description:Binding affinity towards human Corticotropin releasing factor receptor 1 by the displacement of [125I]CRF from CHO cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetCorticotropin-releasing factor receptor 1(Human)
Neurocrine Biosciences

Curated by ChEMBL
LigandPNGBDBM50144193(Dicyclopropylmethyl-propyl-[4-(2,4,6-trimethoxy-ph...)
Affinity DataKi:  15nMAssay Description:Binding affinity towards human Corticotropin releasing factor receptor 1 by the displacement of [125I]CRF from CHO cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetCorticotropin-releasing factor receptor 1(Human)
Neurocrine Biosciences

Curated by ChEMBL
LigandPNGBDBM50144191(Dicyclopropylmethyl-[4-(2,4-dimethoxy-6-methyl-phe...)
Affinity DataKi:  15nMAssay Description:Binding affinity towards human Corticotropin releasing factor receptor 1 by the displacement of [125I]CRF from CHO cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetCorticotropin-releasing factor receptor 1(Human)
Neurocrine Biosciences

Curated by ChEMBL
LigandPNGBDBM50144194(Dicyclopropylmethyl-[4-(2,4-dimethoxy-phenyl)-5-me...)
Affinity DataKi:  19nMAssay Description:Binding affinity towards human Corticotropin releasing factor receptor 1 by the displacement of [125I]CRF from CHO cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetCorticotropin-releasing factor receptor 1(Human)
Neurocrine Biosciences

Curated by ChEMBL
LigandPNGBDBM50144196([4-(4-Bromo-phenyl)-5-methyl-pyrimidin-2-yl]-dicyc...)
Affinity DataKi:  49nMAssay Description:Binding affinity towards human Corticotropin releasing factor receptor 1 by the displacement of [125I]CRF from CHO cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetCorticotropin-releasing factor receptor 1(Human)
Neurocrine Biosciences

Curated by ChEMBL
LigandPNGBDBM50144200(Dicyclopropylmethyl-[4-(2-fluoro-4,6-dimethoxy-phe...)
Affinity DataKi:  63nMAssay Description:Binding affinity towards human Corticotropin releasing factor receptor 1 by the displacement of [125I]CRF from CHO cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetCorticotropin-releasing factor receptor 1(Human)
Neurocrine Biosciences

Curated by ChEMBL
LigandPNGBDBM50144197([4-(4-Bromo-2-methyl-phenyl)-5-methyl-pyrimidin-2-...)
Affinity DataKi:  63nMAssay Description:Binding affinity towards human Corticotropin releasing factor receptor 1 by the displacement of [125I]CRF from CHO cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetCorticotropin-releasing factor receptor 1(Human)
Neurocrine Biosciences

Curated by ChEMBL
LigandPNGBDBM50144203(Allyl-dicyclopropylmethyl-[4-(2,4,6-trimethoxy-phe...)
Affinity DataKi:  100nMAssay Description:Binding affinity towards human Corticotropin releasing factor receptor 1 by the displacement of [125I]CRF from CHO cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetCorticotropin-releasing factor receptor 1(Human)
Neurocrine Biosciences

Curated by ChEMBL
LigandPNGBDBM50144192([4-(4-Bromo-phenyl)-5,6-dimethyl-pyrimidin-2-yl]-d...)
Affinity DataKi:  240nMAssay Description:Binding affinity towards human Corticotropin releasing factor receptor 1 by the displacement of [125I]CRF from CHO cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetCorticotropin-releasing factor receptor 1(Human)
Neurocrine Biosciences

Curated by ChEMBL
LigandPNGBDBM50144202(((R)-Cyclopropyl-phenyl-methyl)-propyl-[4-(2,4,6-t...)
Affinity DataKi:  240nMAssay Description:Binding affinity towards human Corticotropin releasing factor receptor 1 by the displacement of [125I]CRF from CHO cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetCorticotropin-releasing factor receptor 1(Human)
Neurocrine Biosciences

Curated by ChEMBL
LigandPNGBDBM50144190(Propyl-(1-thiophen-2-yl-cyclopropyl)-[4-(2,4,6-tri...)
Affinity DataKi:  250nMAssay Description:Binding affinity towards human Corticotropin releasing factor receptor 1 by the displacement of [125I]CRF from CHO cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetCorticotropin-releasing factor receptor 1(Human)
Neurocrine Biosciences

Curated by ChEMBL
LigandPNGBDBM50144201(Dicyclopropylmethyl-[4-(2,4-dimethoxy-phenyl)-pyri...)
Affinity DataKi:  460nMAssay Description:Binding affinity towards human Corticotropin releasing factor receptor 1 by the displacement of [125I]CRF from CHO cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetCorticotropin-releasing factor receptor 1(Human)
Neurocrine Biosciences

Curated by ChEMBL
LigandPNGBDBM50144199((1-Furan-3-yl-cyclopropyl)-propyl-[4-(2,4,6-trimet...)
Affinity DataKi:  700nMAssay Description:Binding affinity towards human Corticotropin releasing factor receptor 1 by the displacement of [125I]CRF from CHO cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetCorticotropin-releasing factor receptor 1(Human)
Neurocrine Biosciences

Curated by ChEMBL
LigandPNGBDBM50144195(Dicyclopropylmethyl-[4-(2,4-dimethoxy-phenyl)-5-et...)
Affinity DataKi:  860nMAssay Description:Binding affinity towards human Corticotropin releasing factor receptor 1 by the displacement of [125I]CRF from CHO cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetCorticotropin-releasing factor receptor 1(Human)
Neurocrine Biosciences

Curated by ChEMBL
LigandPNGBDBM50144193(Dicyclopropylmethyl-propyl-[4-(2,4,6-trimethoxy-ph...)
Affinity DataEC50:  970nMAssay Description:Effective dose against human Corticotropin releasing factor receptor 1 stimulated ACTH release from primary rat anterior pituitary cell culturesMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetCorticotropin-releasing factor receptor 1(Human)
Neurocrine Biosciences

Curated by ChEMBL
LigandPNGBDBM50144193(Dicyclopropylmethyl-propyl-[4-(2,4,6-trimethoxy-ph...)
Affinity DataEC50:  990nMAssay Description:Effective dose against CRF stimulated cAMP production in CHO cells expressing human Corticotropin releasing factor receptor 1More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetCorticotropin-releasing factor receptor 1(Human)
Neurocrine Biosciences

Curated by ChEMBL
LigandPNGBDBM50144204([4-(2-Chloro-4,6-dimethoxy-phenyl)-pyrimidin-2-yl]...)
Affinity DataEC50:  1.10E+3nMAssay Description:Effective dose against human Corticotropin releasing factor receptor 1 stimulated ACTH release from primary rat anterior pituitary cell culturesMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetCorticotropin-releasing factor receptor 1(Human)
Neurocrine Biosciences

Curated by ChEMBL
LigandPNGBDBM50144204([4-(2-Chloro-4,6-dimethoxy-phenyl)-pyrimidin-2-yl]...)
Affinity DataEC50:  1.60E+3nMAssay Description:Effective dose against CRF stimulated cAMP production in CHO cells expressing human Corticotropin releasing factor receptor 1More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetCorticotropin-releasing factor receptor 1(Human)
Neurocrine Biosciences

Curated by ChEMBL
LigandPNGBDBM50144198(Propyl-(1-thiophen-3-yl-cyclopropyl)-[4-(2,4,6-tri...)
Affinity DataKi:  2.00E+3nMAssay Description:Binding affinity towards human Corticotropin releasing factor receptor 1 by the displacement of [125I]CRF from CHO cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetCorticotropin-releasing factor receptor 1(Human)
Neurocrine Biosciences

Curated by ChEMBL
LigandPNGBDBM50144189(Cyclopentyl-propyl-[4-(2,4,6-trimethoxy-phenyl)-py...)
Affinity DataKi:  2.20E+3nMAssay Description:Binding affinity towards human Corticotropin releasing factor receptor 1 by the displacement of [125I]CRF from CHO cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed