Compile Data Set for Download or QSAR
Report error Found 2 Enz. Inhib. hit(s) with all data for entry = 1891
TargetSerine/threonine-protein kinase Chk1(Human)
Astrazeneca

LigandPNGBDBM14824(JMC514672 Compound 30 | 4-({5-bromo-4-[(4-methoxyp...)
Affinity DataIC50: 450nMpH: 7.5 T: 2°CAssay Description:The compound inhibitory activity was determined by incubation with purified recombinant Chk1 and biotinylated peptide substrate in the presence ATP/[...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/10/2007
Entry Details Article
PubMed
TargetSerine/threonine-protein kinase Chk1(Human)
Astrazeneca

LigandPNGBDBM14825(3-[7-(3-morpholin-4-ylpropoxy)quinazolin-4-yl]-2-o...)
Affinity DataIC50: 4.00E+3nMpH: 7.5 T: 2°CAssay Description:The compound inhibitory activity was determined by incubation with purified recombinant Chk1 and biotinylated peptide substrate in the presence ATP/[...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/10/2007
Entry Details Article
PubMed