Compile Data Set for Download or QSAR
Report error Found 7 Enz. Inhib. hit(s) with all data for entry = 50014450
TargetMelanocortin receptor 4(Mouse)
Millennium Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50142891(2-{2-[2-(5-Bromo-2-methoxy-phenyl)-ethyl]-phenyl}-...)
Affinity DataKi:  39nMAssay Description:Antagonistic activity against mice melanocortin 4 receptor using [125I][NDP]-R-MSH as radioligand in a membrane filtration assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetMelanocortin receptor 4(Mouse)
Millennium Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50142894(2-[2-(5-Bromo-2-methoxy-benzylsulfanyl)-phenyl]-1,...)
Affinity DataKi:  67nMAssay Description:Antagonistic activity against mice melanocortin 4 receptor using [125I][NDP]-R-MSH as radioligand in a membrane filtration assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetMelanocortin receptor 4(Mouse)
Millennium Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50142895(2-phenylimidazoline | ML-253764 | 2-{2-[2-(5-Bromo...)
Affinity DataKi:  160nMAssay Description:Antagonistic activity against mice melanocortin 4 receptor using [125I][NDP]-R-MSH as radioligand in a membrane filtration assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetMelanocortin receptor 4(Mouse)
Millennium Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50142897(2-{2-[2-(5-Bromo-2-methoxy-phenyl)-ethyl]-phenyl}-...)
Affinity DataKi:  220nMAssay Description:Antagonistic activity against mice melanocortin 4 receptor using [125I][NDP]-R-MSH as radioligand in a membrane filtration assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetMelanocortin receptor 4(Mouse)
Millennium Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50142893(2-[2-(2,5-Dichloro-thiophen-3-ylmethylsulfanyl)-ph...)
Affinity DataKi:  2.20E+3nMAssay Description:Antagonistic activity against mice melanocortin 4 receptor using [125I][NDP]-R-MSH as radioligand in a membrane filtration assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetMelanocortin receptor 4(Mouse)
Millennium Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50142896(2-[2-(2-Chloro-6-fluoro-benzylsulfanyl)-phenyl]-1,...)
Affinity DataKi:  2.70E+3nMAssay Description:Antagonistic activity against mice melanocortin 4 receptor using [125I][NDP]-R-MSH as radioligand in a membrane filtration assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetMelanocortin receptor 4(Mouse)
Millennium Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50142892(2-[2-(2,6-Difluoro-benzylsulfanyl)-phenyl]-1,4,5,6...)
Affinity DataKi:  1.58E+4nMAssay Description:Antagonistic activity against mice melanocortin 4 receptor using [125I][NDP]-R-MSH as radioligand in a membrane filtration assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed