Compile Data Set for Download or QSAR
Report error Found 22 Enz. Inhib. hit(s) with all data for entry = 50014429
Target5-hydroxytryptamine receptor 1A(Human)
Arqule

Curated by ChEMBL
LigandPNGBDBM50026926(8-{4-[4-(2-Methoxy-phenyl)-piperazin-1-yl]-butyl}-...)
Affinity DataIC50: 2nMAssay Description:In vitro binding affinity against 5-hydroxytryptamine 1A receptor using [3H]8-OH-DPAT in human CYP3A4 assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
Target5-hydroxytryptamine receptor 1A(Human)
Arqule

Curated by ChEMBL
LigandPNGBDBM50142638(8-[4-(4-Pyrimidin-2-yl-piperazin-1-yl)-pentyl]-8-a...)
Affinity DataIC50: 4nMAssay Description:In vitro binding affinity against 5-hydroxytryptamine 1A receptor using [3H]8-OH-DPAT in human CYP3A4 assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
Target5-hydroxytryptamine receptor 1A(Human)
Arqule

Curated by ChEMBL
LigandPNGBDBM50142640(8-{3-Hydroxy-4-[4-(2-methoxy-phenyl)-piperazin-1-y...)
Affinity DataIC50: 12nMAssay Description:In vitro binding affinity against 5-hydroxytryptamine 1A receptor using [3H]8-OH-DPAT in human CYP3A4 assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
Target5-hydroxytryptamine receptor 1A(Human)
Arqule

Curated by ChEMBL
LigandPNGBDBM50026924(8-[4-(4-Phenyl-piperazin-1-yl)-butyl]-8-aza-spiro[...)
Affinity DataIC50: 15nMAssay Description:In vitro binding affinity against 5-hydroxytryptamine 1A receptor using [3H]8-OH-DPAT in human CYP3A4 assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
Target5-hydroxytryptamine receptor 1A(Human)
Arqule

Curated by ChEMBL
LigandPNGBDBM50001859(BUSPAR | CHEMBL49 | 8-[4-(4-Pyrimidin-2-yl-piperaz...)
Affinity DataIC50: 25nMAssay Description:In vitro binding affinity against 5-hydroxytryptamine 1A receptor using [3H]8-OH-DPAT in human CYP3A4 assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMedPDB3D3D Structure (crystal)
Target5-hydroxytryptamine receptor 1A(Human)
Arqule

Curated by ChEMBL
LigandPNGBDBM50142643(8-{4-[4-(5-Fluoro-pyrimidin-2-yl)-piperazin-1-yl]-...)
Affinity DataIC50: 46nMAssay Description:In vitro binding affinity against 5-hydroxytryptamine 1A receptor using [3H]8-OH-DPAT in human CYP3A4 assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
Target5-hydroxytryptamine receptor 1A(Human)
Arqule

Curated by ChEMBL
LigandPNGBDBM50019422(CHEMBL281720 | 2-[4-(4-Pyrimidin-2-yl-piperazin-1-...)
Affinity DataIC50: 60nMAssay Description:In vitro binding affinity against 5-hydroxytryptamine 1A receptor using [3H]8-OH-DPAT in human CYP3A4 assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
Target5-hydroxytryptamine receptor 1A(Human)
Arqule

Curated by ChEMBL
LigandPNGBDBM50142649(8-{4-[4-(5-Fluoro-pyrimidin-2-yl)-piperazin-1-yl]-...)
Affinity DataIC50: 63nMAssay Description:In vitro binding affinity against 5-hydroxytryptamine 1A receptor using [3H]8-OH-DPAT in human CYP3A4 assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
Target5-hydroxytryptamine receptor 1A(Human)
Arqule

Curated by ChEMBL
LigandPNGBDBM50142647(8-{4-[4-(4-Fluoro-phenyl)-piperazin-1-yl]-butyl}-8...)
Affinity DataIC50: 64nMAssay Description:In vitro binding affinity against 5-hydroxytryptamine 1A receptor using [3H]8-OH-DPAT in human CYP3A4 assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
Target5-hydroxytryptamine receptor 1A(Human)
Arqule

Curated by ChEMBL
LigandPNGBDBM50142639(8-{4-[4-(4-Fluoro-phenyl)-piperazin-1-yl]-3-hydrox...)
Affinity DataIC50: 69nMAssay Description:In vitro binding affinity against 5-hydroxytryptamine 1A receptor using [3H]8-OH-DPAT in human CYP3A4 assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
Target5-hydroxytryptamine receptor 1A(Human)
Arqule

Curated by ChEMBL
LigandPNGBDBM50142648(1-{4-[4-(5-Fluoro-pyrimidin-2-yl)-piperazin-1-yl]-...)
Affinity DataIC50: 87nMAssay Description:In vitro binding affinity against 5-hydroxytryptamine 1A receptor using [3H]8-OH-DPAT in human CYP3A4 assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
Target5-hydroxytryptamine receptor 1A(Human)
Arqule

Curated by ChEMBL
LigandPNGBDBM50142642(8-{4-[4-(4-Fluoro-phenyl)-piperazin-1-yl]-pentyl}-...)
Affinity DataIC50: 99nMAssay Description:In vitro binding affinity against 5-hydroxytryptamine 1A receptor using [3H]8-OH-DPAT in human CYP3A4 assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
Target5-hydroxytryptamine receptor 1A(Human)
Arqule

Curated by ChEMBL
LigandPNGBDBM50005132(4,4-Dimethyl-1-[4-(4-pyrimidin-2-yl-piperazin-1-yl...)
Affinity DataIC50: 114nMAssay Description:In vitro binding affinity against 5-hydroxytryptamine 1A receptor using [3H]8-OH-DPAT in human CYP3A4 assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
Target5-hydroxytryptamine receptor 1A(Human)
Arqule

Curated by ChEMBL
LigandPNGBDBM50142650(1-{4-[4-(5-Fluoro-pyrimidin-2-yl)-piperazin-1-yl]-...)
Affinity DataIC50: 205nMAssay Description:In vitro binding affinity against 5-hydroxytryptamine 1A receptor using [3H]8-OH-DPAT in human CYP3A4 assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
Target5-hydroxytryptamine receptor 1A(Human)
Arqule

Curated by ChEMBL
LigandPNGBDBM50142636(2-{4-[4-(5-Fluoro-pyrimidin-2-yl)-piperazin-1-yl]-...)
Affinity DataIC50: 210nMAssay Description:In vitro binding affinity against 5-hydroxytryptamine 1A receptor using [3H]8-OH-DPAT in human CYP3A4 assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
Target5-hydroxytryptamine receptor 1A(Human)
Arqule

Curated by ChEMBL
LigandPNGBDBM50142644(2-{4-[4-(5-Fluoro-pyrimidin-2-yl)-piperazin-1-yl]-...)
Affinity DataIC50: 440nMAssay Description:In vitro binding affinity against 5-hydroxytryptamine 1A receptor using [3H]8-OH-DPAT in human CYP3A4 assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
Target5-hydroxytryptamine receptor 1A(Human)
Arqule

Curated by ChEMBL
LigandPNGBDBM50142641(8-[4-(2,3,5,6-Tetrahydro-[1,2']bipyrazinyl-4-yl)-b...)
Affinity DataIC50: 460nMAssay Description:In vitro binding affinity against 5-hydroxytryptamine 1A receptor using [3H]8-OH-DPAT in human CYP3A4 assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
Target5-hydroxytryptamine receptor 1A(Human)
Arqule

Curated by ChEMBL
LigandPNGBDBM50142634(8-[3,3-Dimethyl-4-(4-pyrimidin-2-yl-piperazin-1-yl...)
Affinity DataIC50: 710nMAssay Description:In vitro binding affinity against 5-hydroxytryptamine 1A receptor using [3H]8-OH-DPAT in human CYP3A4 assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
Target5-hydroxytryptamine receptor 1A(Human)
Arqule

Curated by ChEMBL
LigandPNGBDBM50142637(8-[3-Hydroxy-4-(4-pyrimidin-2-yl-piperazin-1-yl)-b...)
Affinity DataIC50: 840nMAssay Description:In vitro binding affinity against 5-hydroxytryptamine 1A receptor using [3H]8-OH-DPAT in human CYP3A4 assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
Target5-hydroxytryptamine receptor 1A(Human)
Arqule

Curated by ChEMBL
LigandPNGBDBM50142635(8-{4-[4-(4-Methoxy-phenyl)-piperazin-1-yl]-butyl}-...)
Affinity DataIC50: 930nMAssay Description:In vitro binding affinity against 5-hydroxytryptamine 1A receptor using [3H]8-OH-DPAT in human CYP3A4 assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
Target5-hydroxytryptamine receptor 1A(Human)
Arqule

Curated by ChEMBL
LigandPNGBDBM50142646(8-[3-Hydroxy-4-(2,3,5,6-tetrahydro-[1,2']bipyrazin...)
Affinity DataIC50: 1.00E+3nMAssay Description:In vitro binding affinity against 5-hydroxytryptamine 1A receptor using [3H]8-OH-DPAT in human CYP3A4 assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
Target5-hydroxytryptamine receptor 1A(Human)
Arqule

Curated by ChEMBL
LigandPNGBDBM50142645(8-[3-Hydroxy-3-methyl-4-(4-pyrimidin-2-yl-piperazi...)
Affinity DataIC50: 1.46E+3nMAssay Description:In vitro binding affinity against 5-hydroxytryptamine 1A receptor using [3H]8-OH-DPAT in human CYP3A4 assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed