Compile Data Set for Download or QSAR
Report error Found 43 Enz. Inhib. hit(s) with all data for entry = 50014389
TargetC-C chemokine receptor type 5(Human)
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50119336(Cyclohexyl-{3-phenyl-4-[4-(3-phenyl-propyl)-piperi...)
Affinity DataIC50: 0.200nMAssay Description:Inhibition of human CX3C chemokine receptor 5 from GP120-membrane-based assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetC-C chemokine receptor type 5(Human)
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50141855(Cyclohexyl-{3-[4-(2-ethyl-4-phenethyl-2H-pyrazol-3...)
Affinity DataIC50: 0.600nMAssay Description:Inhibitory activity against human CC chemokine receptor 5More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetC-C chemokine receptor type 5(Human)
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50141841(Cyclohexyl-{3-[4-(4-phenethyl-2-propyl-2H-pyrazol-...)
Affinity DataIC50: 0.600nMAssay Description:Inhibition of human CX3C chemokine receptor 5 from GP120-membrane-based assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetC-C chemokine receptor type 5(Human)
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50141839({3-[4-(4-Benzyl-isoxazol-5-yl)-piperidin-1-ylmethy...)
Affinity DataIC50: 0.800nMAssay Description:Inhibitory activity against human CC chemokine receptor 5More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetC-C chemokine receptor type 5(Human)
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50141869(Cyclohexyl-{3-[4-(2-methyl-4-phenethyl-2H-pyrazol-...)
Affinity DataIC50: 1nMAssay Description:Inhibition of human CX3C chemokine receptor 5 from GP120-membrane-based assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetC-C chemokine receptor type 5(Human)
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50141856({3-[4-(5-Benzyl-2-ethyl-2H-pyrazol-3-yl)-piperidin...)
Affinity DataIC50: 1.20nMAssay Description:Inhibitory concentration to displace [125I]-MIP-1 alpha from human CX3C chemokine receptor 5 expressed in CHO cellMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetC-C chemokine receptor type 5(Human)
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50141858(Cyclohexyl-{3-[4-(4-phenethyl-2H-pyrazol-3-yl)-pip...)
Affinity DataIC50: 1.20nMAssay Description:Inhibitory activity against human CC chemokine receptor 5More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetC-C chemokine receptor type 5(Human)
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50141861({3-[4-(4-Benzyl-isoxazol-3-yl)-piperidin-1-ylmethy...)
Affinity DataIC50: 1.20nMAssay Description:Inhibitory activity against human CC chemokine receptor 5More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetC-C chemokine receptor type 5(Human)
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50141850(Cyclohexyl-(3-{4-[4-(difluoro-phenyl-methyl)-2H-py...)
Affinity DataIC50: 2.10nMAssay Description:Inhibitory activity against human CC chemokine receptor 5More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetC-C chemokine receptor type 5(Human)
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50141856({3-[4-(5-Benzyl-2-ethyl-2H-pyrazol-3-yl)-piperidin...)
Affinity DataIC50: 2.10nMAssay Description:Inhibitory concentration to displace [125I]-MIP-1 alpha from CX3C chemokine receptor 5More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetC-C chemokine receptor type 5(Human)
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50141845((R)-2-((3S,4S)-3-((4-(3-benzyl-1H-pyrazol-5-yl)pip...)
Affinity DataIC50: 2.20nMAssay Description:Inhibitory activity against human CC chemokine receptor 5More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetC-C chemokine receptor type 5(Human)
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50141848(Cyclohexyl-[3-[4-(2-ethyl-5-phenethyl-2H-pyrazol-3...)
Affinity DataIC50: 2.20nMAssay Description:Inhibition of human CX3C chemokine receptor 5 from GP120-membrane-based assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetC-C chemokine receptor type 5(Human)
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50141843(Cyclohexyl-{3-[4-(1-ethyl-4-phenethyl-1H-pyrazol-3...)
Affinity DataIC50: 2.30nMAssay Description:Inhibitory activity against human CC chemokine receptor 5More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetC-C chemokine receptor type 5(Human)
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50104249({1-[(S)-4-(Benzenesulfonyl-methyl-amino)-3-(3-chlo...)
Affinity DataIC50: 2.40nMAssay Description:Inhibition of human CX3C chemokine receptor 5 from GP120-membrane-based assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetC-C chemokine receptor type 5(Human)
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50141838((R)-2-((3S,4S)-3-((4-(4-benzyl-1-ethyl-1H-pyrazol-...)
Affinity DataIC50: 3nMAssay Description:Inhibitory activity against human CC chemokine receptor 5More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetC-C chemokine receptor type 5(Human)
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50141862({3-[4-(5-Benzyl-2-butyl-2H-pyrazol-3-yl)-piperidin...)
Affinity DataIC50: 3nMAssay Description:Inhibitory activity against human CC chemokine receptor 5More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetC-C chemokine receptor type 5(Human)
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50141853([3-{4-[5-(4-Chloro-phenyl)-2H-pyrazol-3-yl]-piperi...)
Affinity DataIC50: 4nMAssay Description:Inhibition of human CX3C chemokine receptor 5 from GP120-membrane-based assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetC-C chemokine receptor type 5(Human)
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50141863((R)-2-((3S,4S)-3-((4-(3-benzyl-1-methyl-1H-pyrazol...)
Affinity DataIC50: 4.20nMAssay Description:Inhibitory activity against human CC chemokine receptor 5More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetC-C chemokine receptor type 5(Human)
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50141844(Cyclohexyl-(3-phenyl-4-{4-[4-(1-phenyl-cyclopropyl...)
Affinity DataIC50: 4.40nMAssay Description:Inhibitory activity against human CC chemokine receptor 5More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetC-C chemokine receptor type 5(Human)
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50141860({3-[4-(5-Benzyl-2-propyl-2H-pyrazol-3-yl)-piperidi...)
Affinity DataIC50: 4.60nMAssay Description:Inhibitory activity against human CC chemokine receptor 5More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetC-C chemokine receptor type 5(Human)
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50141865((3-{4-[5-Benzyl-2-(2,2,2-trifluoro-ethyl)-2H-pyraz...)
Affinity DataIC50: 4.80nMAssay Description:Inhibitory activity against human CC chemokine receptor 5More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetC-C chemokine receptor type 5(Human)
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50141833((R)-2-((3S,4S)-3-((4-(4-benzyl-1H-pyrazol-5-yl)pip...)
Affinity DataIC50: 4.80nMAssay Description:Inhibitory activity against human CC chemokine receptor 5More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetC-C chemokine receptor type 5(Human)
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50141870(Cyclohexyl-(3-{4-[2-ethyl-4-(1-methyl-1-phenyl-eth...)
Affinity DataIC50: 6.90nMAssay Description:Inhibitory activity against human CC chemokine receptor 5More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetC-C chemokine receptor type 5(Human)
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50141835(Cyclohexyl-{3-[4-(5-naphthalen-1-yl-2H-pyrazol-3-y...)
Affinity DataIC50: 7.5nMAssay Description:Inhibition of human CX3C chemokine receptor 5 from GP120-membrane-based assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetC-C chemokine receptor type 5(Human)
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50141851((3-{4-[5-(4-Cyano-phenyl)-2H-pyrazol-3-yl]-piperid...)
Affinity DataIC50: 7.5nMAssay Description:Inhibition of human CX3C chemokine receptor 5 from GP120-membrane-based assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetC-C chemokine receptor type 5(Human)
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50141871({3-[4-(5-Benzyl-2-ethoxycarbonylmethyl-2H-pyrazol-...)
Affinity DataIC50: 9nMAssay Description:Inhibitory activity against human CC chemokine receptor 5More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetC-C chemokine receptor type 5(Human)
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50141872(Cyclohexyl-{3-[4-(4-phenethyl-1-propyl-1H-pyrazol-...)
Affinity DataIC50: 9nMAssay Description:Inhibition of human CX3C chemokine receptor 5 from GP120-membrane-based assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetC-C chemokine receptor type 5(Human)
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50141847(Cyclohexyl-[3-{4-[5-(2,4-dichloro-phenyl)-2H-pyraz...)
Affinity DataIC50: 9nMAssay Description:Inhibition of human CX3C chemokine receptor 5 from GP120-membrane-based assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetC-C chemokine receptor type 5(Human)
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50141840(Cyclohexyl-(3-{4-[2-ethyl-4-(1-phenyl-cyclopropyl)...)
Affinity DataIC50: 11nMAssay Description:Inhibitory activity against human CC chemokine receptor 5More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetC-C chemokine receptor type 5(Human)
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50141837(Cyclohexyl-(3-{4-[4-(1-methyl-1-phenyl-ethyl)-2H-p...)
Affinity DataIC50: 12nMAssay Description:Inhibitory activity against human CC chemokine receptor 5More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetC-C chemokine receptor type 5(Human)
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50141842(Cyclohexyl-(3-(3-fluoro-phenyl)-4-{4-[5-(4-methoxy...)
Affinity DataIC50: 12nMAssay Description:Inhibition of human CX3C chemokine receptor 5 from GP120-membrane-based assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetC-C chemokine receptor type 5(Human)
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50141857(Cyclohexyl-[3-[4-(2-ethyl-5-naphthalen-1-yl-2H-pyr...)
Affinity DataIC50: 16nMAssay Description:Inhibition of human CX3C chemokine receptor 5 from GP120-membrane-based assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetC-C chemokine receptor type 5(Human)
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50141849((3-{4-[5-(4-Cyano-phenyl)-2-ethyl-2H-pyrazol-3-yl]...)
Affinity DataIC50: 16nMAssay Description:Inhibitory activity against human CC chemokine receptor 5More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetC-C chemokine receptor type 5(Human)
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50141846({3-[4-(4-Benzyl-1-ethyl-1H-pyrazol-3-yl)-piperidin...)
Affinity DataIC50: 20nMAssay Description:Inhibitory activity against human CC chemokine receptor 5More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetC-C chemokine receptor type 5(Human)
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50141836(Cyclohexyl-{3-[4-(2-ethyl-5-phenyl-2H-pyrazol-3-yl...)
Affinity DataIC50: 22nMAssay Description:Inhibitory activity against human CC chemokine receptor 5More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetC-C chemokine receptor type 5(Human)
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50141854(Cyclohexyl-{3-[4-(1-methyl-4-phenethyl-1H-pyrazol-...)
Affinity DataIC50: 23nMAssay Description:Inhibition of human CX3C chemokine receptor 5 from GP120-membrane-based assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetC-C chemokine receptor type 5(Human)
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50141859({3-[4-(4-Benzoyl-2-ethyl-2H-pyrazol-3-yl)-piperidi...)
Affinity DataIC50: 23nMAssay Description:Inhibitory activity against human CC chemokine receptor 5More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetC-C chemokine receptor type 5(Human)
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50141864({3-[4-(5-Benzyl-2-carboxymethyl-2H-pyrazol-3-yl)-p...)
Affinity DataIC50: 33nMAssay Description:Inhibitory activity against human CC chemokine receptor 5More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetC-C chemokine receptor type 5(Human)
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50141834({3-[4-(4-Benzoyl-2H-pyrazol-3-yl)-piperidin-1-ylme...)
Affinity DataIC50: 41nMAssay Description:Inhibitory activity against human CC chemokine receptor 5More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetC-C chemokine receptor type 5(Human)
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50141866({3-[4-(5-Benzyl-1-ethyl-1H-pyrazol-3-yl)-piperidin...)
Affinity DataIC50: 76nMAssay Description:Inhibitory activity against human CC chemokine receptor 5More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetC-C chemokine receptor type 5(Human)
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50141852({3-[4-(5-Benzyl-3-ethyl-pyrazol-1-yl)-piperidin-1-...)
Affinity DataIC50: 78nMAssay Description:Inhibitory activity against human Chemokine receptor 5 when co-administered with compound 8fMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetC-C chemokine receptor type 5(Human)
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50141868(Cyclohexyl-{3-[4-(5-ethyl-3-phenethyl-pyrazol-1-yl...)
Affinity DataIC50: 105nMAssay Description:Inhibitory activity against human CX3C chemokine receptor 5 when co-administered with compound 8gMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetC-C chemokine receptor type 5(Human)
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50141867((3-{4-[5-(4-Aminomethyl-phenyl)-2-ethyl-2H-pyrazol...)
Affinity DataIC50: 112nMAssay Description:Inhibitory activity against human CC chemokine receptor 5More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed