Compile Data Set for Download or QSAR
Report error Found 16 Enz. Inhib. hit(s) with all data for entry = 50014317
TargetC-X-C chemokine receptor type 2(Human)
Glaxosmithkline

Curated by ChEMBL
LigandPNGBDBM50140791(1-(3-Bromo-4-cyano-2-hydroxy-phenyl)-3-(2-bromo-ph...)
Affinity DataIC50: 6nMAssay Description:Inhibition of binding of IL-8 to membranes of cloned CXC chemokine receptor 2 expressed in CHO Cells using [125I]IL-8 radioligandMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetC-X-C chemokine receptor type 2(Human)
Glaxosmithkline

Curated by ChEMBL
LigandPNGBDBM50140795(1-(2-Bromo-phenyl)-3-(3-chloro-4-cyano-2-hydroxy-p...)
Affinity DataIC50: 22nMAssay Description:Inhibition of binding of IL-8 to membranes of cloned CXC chemokine receptor 2 expressed in CHO Cells using [125I]IL-8 radioligandMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetC-X-C chemokine receptor type 2(Human)
Glaxosmithkline

Curated by ChEMBL
LigandPNGBDBM50140796(1-(2-Bromo-phenyl)-3-(4-cyano-2-hydroxy-phenyl)-ur...)
Affinity DataIC50: 25nMAssay Description:Inhibition of binding of IL-8 to membranes of cloned CXC chemokine receptor 2 expressed in CHO Cells using [125I]IL-8 radioligandMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetC-X-C chemokine receptor type 2(Human)
Glaxosmithkline

Curated by ChEMBL
LigandPNGBDBM50140789(1-(2-Bromo-phenyl)-3-(4-chloro-3-cyano-2-hydroxy-p...)
Affinity DataIC50: 57nMAssay Description:Inhibition of binding of IL-8 to membranes of cloned CXC chemokine receptor 2 expressed in CHO Cells using [125I]IL-8 radioligandMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetC-X-C chemokine receptor type 2(Human)
Glaxosmithkline

Curated by ChEMBL
LigandPNGBDBM50140792(1-(4-Cyano-2-hydroxy-phenyl)-3-phenyl-urea | 1-(4-...)
Affinity DataIC50: 200nMAssay Description:Inhibition of binding of IL-8 to membranes of cloned CXC chemokine receptor 2 expressed in CHO Cells using [125I]IL-8 radioligandMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetC-X-C chemokine receptor type 2(Human)
Glaxosmithkline

Curated by ChEMBL
LigandPNGBDBM50140794(1-(2-Hydroxy-4-nitro-phenyl)-3-phenyl-urea | 1-(2-...)
Affinity DataIC50: 320nMAssay Description:Inhibition of binding of IL-8 to membranes of cloned CXC chemokine receptor 2 expressed in CHO Cells using [125I]IL-8 radioligandMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetC-X-C chemokine receptor type 2(Human)
Glaxosmithkline

Curated by ChEMBL
LigandPNGBDBM50140793(1-(2-Hydroxy-3-nitro-phenyl)-3-phenyl-urea | CHEMB...)
Affinity DataIC50: 860nMAssay Description:Inhibition of binding of IL-8 to membranes of cloned CXC chemokine receptor 2 expressed in CHO Cells using [125I]IL-8 radioligandMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetC-X-C chemokine receptor type 1(Human)
Glaxosmithkline

Curated by ChEMBL
LigandPNGBDBM50140791(1-(3-Bromo-4-cyano-2-hydroxy-phenyl)-3-(2-bromo-ph...)
Affinity DataIC50: 2.60E+3nMAssay Description:Inhibition of binding of IL-8 to membranes of cloned CXC chemokine receptor 1 expressed in CHO Cells using [125I]IL-8 radioligandMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetC-X-C chemokine receptor type 1(Human)
Glaxosmithkline

Curated by ChEMBL
LigandPNGBDBM50140795(1-(2-Bromo-phenyl)-3-(3-chloro-4-cyano-2-hydroxy-p...)
Affinity DataIC50: 4.20E+3nMAssay Description:Inhibition of binding of IL-8 to membranes of cloned CXC chemokine receptor 1 expressed in CHO Cells using [125I]IL-8 radioligandMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetC-X-C chemokine receptor type 2(Human)
Glaxosmithkline

Curated by ChEMBL
LigandPNGBDBM50140790(1-(2-Hydroxy-5-nitro-phenyl)-3-phenyl-urea | CHEMB...)
Affinity DataIC50: 1.09E+4nMAssay Description:Inhibition of binding of IL-8 to membranes of cloned CXC chemokine receptor 2 expressed in CHO Cells using [125I]IL-8 radioligandMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetC-X-C chemokine receptor type 1(Human)
Glaxosmithkline

Curated by ChEMBL
LigandPNGBDBM50140789(1-(2-Bromo-phenyl)-3-(4-chloro-3-cyano-2-hydroxy-p...)
Affinity DataIC50: 1.11E+4nMAssay Description:Inhibition of binding of IL-8 to membranes of cloned CXC chemokine receptor 1 expressed in CHO Cells using [125I]IL-8 radioligandMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetC-X-C chemokine receptor type 1(Human)
Glaxosmithkline

Curated by ChEMBL
LigandPNGBDBM50140796(1-(2-Bromo-phenyl)-3-(4-cyano-2-hydroxy-phenyl)-ur...)
Affinity DataIC50: 1.51E+4nMAssay Description:Inhibition of binding of IL-8 to membranes of cloned CXC chemokine receptor 1 expressed in CHO Cells using [125I]IL-8 radioligandMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetC-X-C chemokine receptor type 1(Human)
Glaxosmithkline

Curated by ChEMBL
LigandPNGBDBM50140794(1-(2-Hydroxy-4-nitro-phenyl)-3-phenyl-urea | 1-(2-...)
Affinity DataIC50: 1.82E+4nMAssay Description:Inhibition of binding of IL-8 to membranes of cloned CXC chemokine receptor 1 expressed in CHO Cells using [125I]IL-8 radioligandMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetC-X-C chemokine receptor type 1(Human)
Glaxosmithkline

Curated by ChEMBL
LigandPNGBDBM50140792(1-(4-Cyano-2-hydroxy-phenyl)-3-phenyl-urea | 1-(4-...)
Affinity DataIC50: 2.10E+4nMAssay Description:Inhibition of binding of IL-8 to membranes of cloned CXC chemokine receptor 1 expressed in CHO Cells using [125I]IL-8 radioligandMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetC-X-C chemokine receptor type 1(Human)
Glaxosmithkline

Curated by ChEMBL
LigandPNGBDBM50140793(1-(2-Hydroxy-3-nitro-phenyl)-3-phenyl-urea | CHEMB...)
Affinity DataIC50: 3.32E+4nMAssay Description:Inhibition of binding of IL-8 to membranes of cloned CXC chemokine receptor 1 expressed in CHO Cells using [125I]IL-8 radioligandMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetC-X-C chemokine receptor type 1(Human)
Glaxosmithkline

Curated by ChEMBL
LigandPNGBDBM50140790(1-(2-Hydroxy-5-nitro-phenyl)-3-phenyl-urea | CHEMB...)
Affinity DataIC50: 4.62E+4nMAssay Description:Inhibition of binding of IL-8 to membranes of cloned CXC chemokine receptor 1 expressed in CHO Cells using [125I]IL-8 radioligandMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed