Compile Data Set for Download or QSAR
Report error Found 14 Enz. Inhib. hit(s) with all data for entry = 50014312
TargetPhenylalanine--tRNA ligase, mitochondrial(Human)
Cubist Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50140728(13N-(3,4-dichlorophenyl)-2-hydroxy-11-oxo-14-pheny...)
Affinity DataIC50: 170nMAssay Description:Compound was evaluated for the inhibitory activity against Escherichia coli phenylalanyl-tRNA synthetaseMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetPhenylalanine--tRNA ligase, mitochondrial(Human)
Cubist Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50140728(13N-(3,4-dichlorophenyl)-2-hydroxy-11-oxo-14-pheny...)
Affinity DataIC50: 260nMAssay Description:Compound was evaluated for the inhibitory activity against Staphylococcus aureus phenylalanyl-tRNA synthetaseMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetPhenylalanine--tRNA ligase, mitochondrial(Human)
Cubist Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50140729(13N-(3,4-dichlorophenyl)-2-hydroxy-11-oxo-14-pheny...)
Affinity DataIC50: 470nMAssay Description:Compound was evaluated for the inhibitory activity against Escherichia coli phenylalanyl-tRNA synthetaseMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetPhenylalanine--tRNA ligase, mitochondrial(Human)
Cubist Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50140729(13N-(3,4-dichlorophenyl)-2-hydroxy-11-oxo-14-pheny...)
Affinity DataIC50: 510nMAssay Description:Compound was evaluated for the inhibitory activity against Staphylococcus aureus phenylalanyl-tRNA synthetaseMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetPhenylalanine--tRNA ligase, mitochondrial(Human)
Cubist Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50140727(5-(3,4-dichlorophenyl)-3-phenyl-(3R,3aR,6aS)-spiro...)
Affinity DataIC50: 2.00E+3nMAssay Description:Compound was evaluated for the inhibitory activity against Staphylococcus aureus phenylalanyl-tRNA synthetaseMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetPhenylalanine--tRNA ligase, mitochondrial(Human)
Cubist Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50140725(13N-(3,4-dichlorophenyl)-2,11-dioxo-14-phenyl-(1R,...)
Affinity DataIC50: 2.60E+3nMAssay Description:Compound was evaluated for the inhibitory activity against Staphylococcus aureus phenylalanyl-tRNA synthetaseMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetPhenylalanine--tRNA ligase, mitochondrial(Human)
Cubist Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50140725(13N-(3,4-dichlorophenyl)-2,11-dioxo-14-phenyl-(1R,...)
Affinity DataIC50: 3.10E+3nMAssay Description:Compound was evaluated for the inhibitory activity against Staphylococcus aureus phenylalanyl-tRNA synthetaseMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetPhenylalanine--tRNA ligase, mitochondrial(Human)
Cubist Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50140726(13N-(3,4-dichlorophenyl)-2-hydroxy-11-oxo-14-pheny...)
Affinity DataIC50: 4.90E+3nMAssay Description:Compound was evaluated for the inhibitory activity against Escherichia coli phenylalanyl-tRNA synthetaseMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetPhenylalanine--tRNA ligase, mitochondrial(Human)
Cubist Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50140726(13N-(3,4-dichlorophenyl)-2-hydroxy-11-oxo-14-pheny...)
Affinity DataIC50: 4.90E+3nMAssay Description:Compound was evaluated for the inhibitory activity against Staphylococcus aureus phenylalanyl-tRNA synthetaseMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetPhenylalanine--tRNA ligase, mitochondrial(Human)
Cubist Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50140727(5-(3,4-dichlorophenyl)-3-phenyl-(3R,3aR,6aS)-spiro...)
Affinity DataIC50: 5.00E+3nMAssay Description:Compound was evaluated for the inhibitory activity against Staphylococcus aureus phenylalanyl-tRNA synthetaseMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetPhenylalanine--tRNA ligase, mitochondrial(Human)
Cubist Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50140730(4-(3,4-dichlorophenylcarbamoyl)-1',3'-dioxo-5-phen...)
Affinity DataIC50: 1.10E+4nMAssay Description:Compound was evaluated for the inhibitory activity against Escherichia coli phenylalanyl-tRNA synthetaseMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetPhenylalanine--tRNA ligase, mitochondrial(Human)
Cubist Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50140726(13N-(3,4-dichlorophenyl)-2-hydroxy-11-oxo-14-pheny...)
Affinity DataIC50: 1.40E+4nMAssay Description:Compound was evaluated for the inhibitory activity against Staphylococcus aureus phenylalanyl-tRNA synthetaseMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetPhenylalanine--tRNA ligase, mitochondrial(Human)
Cubist Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50140730(4-(3,4-dichlorophenylcarbamoyl)-1',3'-dioxo-5-phen...)
Affinity DataIC50: 3.30E+4nMAssay Description:Compound was evaluated for the inhibitory activity against Staphylococcus aureus phenylalanyl-tRNA synthetaseMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetPhenylalanine--tRNA ligase, mitochondrial(Human)
Cubist Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50140726(13N-(3,4-dichlorophenyl)-2-hydroxy-11-oxo-14-pheny...)
Affinity DataIC50: 1.00E+5nMAssay Description:Compound was evaluated for the inhibitory activity against Staphylococcus aureus phenylalanyl-tRNA synthetaseMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed