Compile Data Set for Download or QSAR
Report error Found 44 Enz. Inhib. hit(s) with all data for entry = 50014204
Target5-hydroxytryptamine receptor 1D(Human)
Nps Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50005835(Sumax | 3-[2-(dimethylamino)ethyl]-N-methylindole-...)
Affinity DataKi:  3.40nMAssay Description:Binding affinity was evaluated at the cloned human 5-hydroxytryptamine 1D receptorMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
Target5-hydroxytryptamine receptor 1D(Human)
Nps Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50139503(4-Chloro-N-{4-[3-(2-pyrrolidin-1-yl-ethyl)-1H-indo...)
Affinity DataKi:  6.10nMAssay Description:Binding affinity was evaluated at the cloned human 5-hydroxytryptamine 1D receptorMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
Target5-hydroxytryptamine receptor 1D(Human)
Nps Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50139505(4-Methoxy-N-{4-[3-(2-pyrrolidin-1-yl-ethyl)-1H-ind...)
Affinity DataKi:  6.20nMAssay Description:Binding affinity was evaluated at the cloned human 5-hydroxytryptamine 1D receptorMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
Target5-hydroxytryptamine receptor 1D(Human)
Nps Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50139513(4-Methyl-N-{4-[3-(2-pyrrolidin-1-yl-ethyl)-1H-indo...)
Affinity DataKi:  7.40nMAssay Description:Binding affinity was evaluated at the cloned human 5-hydroxytryptamine 1D receptorMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
Target5-hydroxytryptamine receptor 1B(Human)
Nps Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50005835(Sumax | 3-[2-(dimethylamino)ethyl]-N-methylindole-...)
Affinity DataKi:  7.70nMAssay Description:Binding affinity was evaluated at the cloned human 5-hydroxytryptamine 1B receptorMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
Target5-hydroxytryptamine receptor 1D(Human)
Nps Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50139502(4-Methoxy-N-{4-[3-(2-pyrrolidin-1-yl-ethyl)-1H-ind...)
Affinity DataKi:  7.80nMAssay Description:Binding affinity was evaluated at the cloned human 5-hydroxytryptamine 1D receptorMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
Target5-hydroxytryptamine receptor 1D(Human)
Nps Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50133460(Dimethyl-{2-[5-(1-methyl-1,2,3,6-tetrahydro-pyridi...)
Affinity DataKi:  8nMAssay Description:Binding affinity was evaluated at the cloned human 5-hydroxytryptamine 1D receptorMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
Target5-hydroxytryptamine receptor 1D(Human)
Nps Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50139504(4-Methyl-N-{4-[3-(2-pyrrolidin-1-yl-ethyl)-1H-indo...)
Affinity DataKi:  8.5nMAssay Description:Binding affinity was evaluated at the cloned human 5-hydroxytryptamine 1D receptorMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
Target5-hydroxytryptamine receptor 1D(Human)
Nps Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50139519(N-{4-[3-(2-Pyrrolidin-1-yl-ethyl)-1H-indol-5-yl]-3...)
Affinity DataKi:  8.60nMAssay Description:Binding affinity was evaluated at the cloned human 5-hydroxytryptamine 1D receptorMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
Target5-hydroxytryptamine receptor 1D(Human)
Nps Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50139514(Naphthalene-1-carboxylic acid {4-[3-(2-pyrrolidin-...)
Affinity DataKi:  8.80nMAssay Description:Binding affinity was evaluated at the cloned human 5-hydroxytryptamine 1D receptorMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
Target5-hydroxytryptamine receptor 1D(Human)
Nps Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50139510(5-[1-(4-Chloro-benzenesulfonyl)-1,2,3,6-tetrahydro...)
Affinity DataKi:  9.30nMAssay Description:Binding affinity was evaluated at the cloned human 5-hydroxytryptamine 1D receptorMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
Target5-hydroxytryptamine receptor 1D(Human)
Nps Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50139517(N-{4-[3-(2-Pyrrolidin-1-yl-ethyl)-1H-indol-5-yl]-3...)
Affinity DataKi:  9.5nMAssay Description:Binding affinity was evaluated at the cloned human 5-hydroxytryptamine 1D receptorMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
Target5-hydroxytryptamine receptor 1D(Human)
Nps Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50139506(5-[1-(4-Methoxy-benzenesulfonyl)-1,2,3,6-tetrahydr...)
Affinity DataKi:  11nMAssay Description:Binding affinity was evaluated at the cloned human 5-hydroxytryptamine 1D receptorMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
Target5-hydroxytryptamine receptor 1D(Human)
Nps Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50139518(Cyclohexanecarbothioic acid {4-[3-(2-pyrrolidin-1-...)
Affinity DataKi:  11nMAssay Description:Binding affinity was evaluated at the cloned human 5-hydroxytryptamine 1D receptorMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
Target5-hydroxytryptamine receptor 1D(Human)
Nps Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50139512(3-(2-Pyrrolidin-1-yl-ethyl)-5-[1-(toluene-4-sulfon...)
Affinity DataKi:  12nMAssay Description:Binding affinity was evaluated at the cloned human 5-hydroxytryptamine 1D receptorMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
Target5-hydroxytryptamine receptor 1D(Human)
Nps Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50139520(4-Chloro-N-{4-[3-(2-pyrrolidin-1-yl-ethyl)-1H-indo...)
Affinity DataKi:  12nMAssay Description:Binding affinity was evaluated at the cloned human 5-hydroxytryptamine 1D receptorMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
Target5-hydroxytryptamine receptor 1D(Human)
Nps Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50139516(Naphthalene-1-carbothioic acid {4-[3-(2-pyrrolidin...)
Affinity DataKi:  16nMAssay Description:Binding affinity was evaluated at the cloned human 5-hydroxytryptamine 1D receptorMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
Target5-hydroxytryptamine receptor 1D(Human)
Nps Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50139508(5-(1-Benzenesulfonyl-1,2,3,6-tetrahydro-pyridin-4-...)
Affinity DataKi:  21nMAssay Description:Binding affinity was evaluated at the cloned human 5-hydroxytryptamine 1D receptorMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
Target5-hydroxytryptamine receptor 1D(Human)
Nps Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50139507(5-[1-(Naphthalene-1-sulfonyl)-1,2,3,6-tetrahydro-p...)
Affinity DataKi:  27nMAssay Description:Binding affinity was evaluated at the cloned human 5-hydroxytryptamine 1D receptorMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
Target5-hydroxytryptamine receptor 1D(Human)
Nps Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50139511(Adamantane-1-carbothioic acid {4-[3-(2-pyrrolidin-...)
Affinity DataKi:  29nMAssay Description:Binding affinity was evaluated at the cloned human 5-hydroxytryptamine 1D receptorMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
Target5-hydroxytryptamine receptor 1D(Human)
Nps Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50139515(Adamantane-1-carboxylic acid {4-[3-(2-pyrrolidin-1...)
Affinity DataKi:  29nMAssay Description:Binding affinity was evaluated at the cloned human 5-hydroxytryptamine 1D receptorMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
Target5-hydroxytryptamine receptor 1D(Human)
Nps Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50139521(Cyclohexanecarboxylic acid {4-[3-(2-pyrrolidin-1-y...)
Affinity DataKi:  29nMAssay Description:Binding affinity was evaluated at the cloned human 5-hydroxytryptamine 1D receptorMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
Target5-hydroxytryptamine receptor 1B(Human)
Nps Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50139513(4-Methyl-N-{4-[3-(2-pyrrolidin-1-yl-ethyl)-1H-indo...)
Affinity DataKi:  32nMAssay Description:Binding affinity was evaluated at the cloned human 5-hydroxytryptamine 1B receptorMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
Target5-hydroxytryptamine receptor 1B(Human)
Nps Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50139520(4-Chloro-N-{4-[3-(2-pyrrolidin-1-yl-ethyl)-1H-indo...)
Affinity DataKi:  36nMAssay Description:Binding affinity was evaluated at the cloned human 5-hydroxytryptamine 1B receptorMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
Target5-hydroxytryptamine receptor 1B(Human)
Nps Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50139518(Cyclohexanecarbothioic acid {4-[3-(2-pyrrolidin-1-...)
Affinity DataKi:  38nMAssay Description:Binding affinity was evaluated at the cloned human 5-hydroxytryptamine 1B receptorMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
Target5-hydroxytryptamine receptor 1B(Human)
Nps Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50139519(N-{4-[3-(2-Pyrrolidin-1-yl-ethyl)-1H-indol-5-yl]-3...)
Affinity DataKi:  40nMAssay Description:Binding affinity was evaluated at the cloned human 5-hydroxytryptamine 1B receptorMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
Target5-hydroxytryptamine receptor 1B(Human)
Nps Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50139502(4-Methoxy-N-{4-[3-(2-pyrrolidin-1-yl-ethyl)-1H-ind...)
Affinity DataKi:  44nMAssay Description:Binding affinity was evaluated at the cloned human 5-hydroxytryptamine 1B receptorMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
Target5-hydroxytryptamine receptor 1B(Human)
Nps Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50139505(4-Methoxy-N-{4-[3-(2-pyrrolidin-1-yl-ethyl)-1H-ind...)
Affinity DataKi:  58nMAssay Description:Binding affinity was evaluated at the cloned human 5-hydroxytryptamine 1B receptorMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
Target5-hydroxytryptamine receptor 1B(Human)
Nps Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50139504(4-Methyl-N-{4-[3-(2-pyrrolidin-1-yl-ethyl)-1H-indo...)
Affinity DataKi:  63nMAssay Description:Binding affinity was evaluated at the cloned human 5-hydroxytryptamine 1B receptorMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
Target5-hydroxytryptamine receptor 1B(Human)
Nps Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50139515(Adamantane-1-carboxylic acid {4-[3-(2-pyrrolidin-1...)
Affinity DataKi:  64nMAssay Description:Binding affinity was evaluated at the cloned human 5-hydroxytryptamine 1B receptorMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
Target5-hydroxytryptamine receptor 1B(Human)
Nps Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50139514(Naphthalene-1-carboxylic acid {4-[3-(2-pyrrolidin-...)
Affinity DataKi:  65nMAssay Description:Binding affinity was evaluated at the cloned human 5-hydroxytryptamine 1B receptorMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
Target5-hydroxytryptamine receptor 1B(Human)
Nps Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50139517(N-{4-[3-(2-Pyrrolidin-1-yl-ethyl)-1H-indol-5-yl]-3...)
Affinity DataKi:  68nMAssay Description:Binding affinity was evaluated at the cloned human 5-hydroxytryptamine 1B receptorMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
Target5-hydroxytryptamine receptor 1D(Human)
Nps Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50139509(3-(2-Pyrrolidin-1-yl-ethyl)-5-(1,2,3,6-tetrahydro-...)
Affinity DataKi:  74nMAssay Description:Binding affinity was evaluated at the cloned human 5-hydroxytryptamine 1D receptorMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
Target5-hydroxytryptamine receptor 1B(Human)
Nps Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50139503(4-Chloro-N-{4-[3-(2-pyrrolidin-1-yl-ethyl)-1H-indo...)
Affinity DataKi:  82nMAssay Description:Binding affinity was evaluated at the cloned human 5-hydroxytryptamine 1B receptorMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
Target5-hydroxytryptamine receptor 1B(Human)
Nps Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50139516(Naphthalene-1-carbothioic acid {4-[3-(2-pyrrolidin...)
Affinity DataKi:  95nMAssay Description:Binding affinity was evaluated at the cloned human 5-hydroxytryptamine 1B receptorMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
Target5-hydroxytryptamine receptor 1B(Human)
Nps Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50139510(5-[1-(4-Chloro-benzenesulfonyl)-1,2,3,6-tetrahydro...)
Affinity DataKi:  110nMAssay Description:Binding affinity was evaluated at the cloned human 5-hydroxytryptamine 1B receptorMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
Target5-hydroxytryptamine receptor 1B(Human)
Nps Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50139521(Cyclohexanecarboxylic acid {4-[3-(2-pyrrolidin-1-y...)
Affinity DataKi:  130nMAssay Description:Binding affinity was evaluated at the cloned human 5-hydroxytryptamine 1B receptorMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
Target5-hydroxytryptamine receptor 1B(Human)
Nps Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50139512(3-(2-Pyrrolidin-1-yl-ethyl)-5-[1-(toluene-4-sulfon...)
Affinity DataKi:  140nMAssay Description:Binding affinity was evaluated at the cloned human 5-hydroxytryptamine 1B receptorMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
Target5-hydroxytryptamine receptor 1B(Human)
Nps Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50139506(5-[1-(4-Methoxy-benzenesulfonyl)-1,2,3,6-tetrahydr...)
Affinity DataKi:  140nMAssay Description:Binding affinity was evaluated at the cloned human 5-hydroxytryptamine 1B receptorMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
Target5-hydroxytryptamine receptor 1B(Human)
Nps Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50139511(Adamantane-1-carbothioic acid {4-[3-(2-pyrrolidin-...)
Affinity DataKi:  170nMAssay Description:Binding affinity was evaluated at the cloned human 5-hydroxytryptamine 1B receptorMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
Target5-hydroxytryptamine receptor 1B(Human)
Nps Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50139507(5-[1-(Naphthalene-1-sulfonyl)-1,2,3,6-tetrahydro-p...)
Affinity DataKi:  410nMAssay Description:Binding affinity was evaluated at the cloned human 5-hydroxytryptamine 1B receptorMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
Target5-hydroxytryptamine receptor 1B(Human)
Nps Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50139508(5-(1-Benzenesulfonyl-1,2,3,6-tetrahydro-pyridin-4-...)
Affinity DataKi:  440nMAssay Description:Binding affinity was evaluated at the cloned human 5-hydroxytryptamine 1B receptorMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
Target5-hydroxytryptamine receptor 1B(Human)
Nps Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50133460(Dimethyl-{2-[5-(1-methyl-1,2,3,6-tetrahydro-pyridi...)
Affinity DataKi:  610nMAssay Description:Binding affinity was evaluated at the cloned human 5-hydroxytryptamine 1B receptorMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
Target5-hydroxytryptamine receptor 1B(Human)
Nps Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50139509(3-(2-Pyrrolidin-1-yl-ethyl)-5-(1,2,3,6-tetrahydro-...)
Affinity DataKi:  760nMAssay Description:Binding affinity was evaluated at the cloned human 5-hydroxytryptamine 1B receptorMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed