Compile Data Set for Download or QSAR
Report error Found 21 Enz. Inhib. hit(s) with all data for entry = 50035380
TargetBeta-secretase 1(Human)
Eli Lilly

Curated by ChEMBL
LigandPNGBDBM16250(CHEMBL290001 | tert-butyl N-[(1S)-1-{[(1S)-1-{[(1R...)
Affinity DataKi:  2.5nMAssay Description:Binding affinity towards Beta-secretase 1 expressed in HEK293 (Human Embryonic Kidney) cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/10/2012
Entry Details Article
PubMed
TargetBeta-secretase 1(Human)
Eli Lilly

Curated by ChEMBL
LigandPNGBDBM50137678([(S)-1-((S)-1-{(3S,4S)-1-Benzyl-4-[(R)-1-((S)-benz...)
Affinity DataIC50: 28nMAssay Description:In vitro inhibition of Beta-secretase-1 in HEK293 (Human Embryonic Kidney) cell line.More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/10/2012
Entry Details Article
PubMed
TargetBeta-secretase 1(Human)
Eli Lilly

Curated by ChEMBL
LigandPNGBDBM50137686({(S)-1-[(S)-1-((2S,4S)-1-Benzyl-2-hydroxy-4-{(R)-2...)
Affinity DataIC50: 41nMAssay Description:In vitro inhibition of Beta-secretase-1 in HEK293 (Human Embryonic Kidney) cell line.More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/10/2012
Entry Details Article
PubMed
TargetBeta-secretase 1(Human)
Eli Lilly

Curated by ChEMBL
LigandPNGBDBM50366890(CHEMBL1790594)
Affinity DataIC50: 42nMAssay Description:In vitro inhibition of Beta-secretase-1 in HEK293 (Human Embryonic Kidney) cell line.More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/10/2012
Entry Details Article
PubMed
TargetBeta-secretase 1(Human)
Eli Lilly

Curated by ChEMBL
LigandPNGBDBM50137681({(S)-1-[(S)-1-((2S,4S)-1-Benzyl-2-hydroxy-4-{(R)-2...)
Affinity DataIC50: 45nMAssay Description:In vitro inhibition of Beta-secretase-1 in HEK293 (Human Embryonic Kidney) cell line.More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/10/2012
Entry Details Article
PubMed
TargetBeta-secretase 1(Human)
Eli Lilly

Curated by ChEMBL
LigandPNGBDBM50137691((S)-5-{(S)-2-[(S)-2-((S)-2-Amino-4-carboxy-butyryl...)
Affinity DataIC50: 49nMAssay Description:In vitro inhibition of Beta-secretase-1 in HEK293 (Human Embryonic Kidney) cell line.More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/10/2012
Entry Details Article
PubMed
TargetBeta-secretase 1(Human)
Eli Lilly

Curated by ChEMBL
LigandPNGBDBM50137693({(S)-1-[(S)-1-((2S,4S)-1-Benzyl-2-hydroxy-4-{(R)-2...)
Affinity DataIC50: 60nMAssay Description:In vitro inhibition of Beta-secretase-1 in HEK293 (Human Embryonic Kidney) cell line.More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/10/2012
Entry Details Article
PubMed
TargetBeta-secretase 1(Human)
Eli Lilly

Curated by ChEMBL
LigandPNGBDBM50137683({(S)-1-[(S)-1-((2S,4S)-1-Benzyl-2-hydroxy-4-{(R)-2...)
Affinity DataIC50: 63nMAssay Description:In vitro inhibition of Beta-secretase-1 in HEK293 (Human Embryonic Kidney) cell line.More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/10/2012
Entry Details Article
PubMed
TargetBeta-secretase 1(Human)
Eli Lilly

Curated by ChEMBL
LigandPNGBDBM50137690({(S)-1-[(S)-1-((2S,4S)-1-Benzyl-2-hydroxy-4-{(R)-2...)
Affinity DataIC50: 70nMAssay Description:In vitro inhibition of Beta-secretase-1 in HEK293 (Human Embryonic Kidney) cell line.More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/10/2012
Entry Details Article
PubMed
TargetBeta-secretase 1(Human)
Eli Lilly

Curated by ChEMBL
LigandPNGBDBM50137684({(S)-1-[(S)-1-((2S,4S)-1-Benzyl-2-hydroxy-4-{(R)-2...)
Affinity DataIC50: 75nMAssay Description:In vitro inhibition of Beta-secretase-1 in HEK293 (Human Embryonic Kidney) cell line.More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/10/2012
Entry Details Article
PubMed
TargetBeta-secretase 1(Human)
Eli Lilly

Curated by ChEMBL
LigandPNGBDBM15799(CHEMBL81671 | tert-butyl N-[(1S)-1-{[(1S)-1-{[(2S,...)
Affinity DataIC50: 82nMAssay Description:In vitro inhibition of Beta-secretase-1 in HEK293 (Human Embryonic Kidney) cell line.More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/10/2012
Entry Details Article
PubMed
TargetBeta-secretase 1(Human)
Eli Lilly

Curated by ChEMBL
LigandPNGBDBM50137682({(S)-1-[(S)-1-((2S,4S)-1-Benzyl-2-hydroxy-4-{(R)-2...)
Affinity DataIC50: 118nMAssay Description:In vitro inhibition of Beta-secretase-1 in HEK293 (Human Embryonic Kidney) cell line.More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/10/2012
Entry Details Article
PubMed
TargetBeta-secretase 1(Human)
Eli Lilly

Curated by ChEMBL
LigandPNGBDBM50137688({(S)-1-[(S)-1-((2S,4S)-1-Benzyl-2-hydroxy-4-{(R)-2...)
Affinity DataIC50: 127nMAssay Description:In vitro inhibition of Beta-secretase-1 in HEK293 (Human Embryonic Kidney) cell line.More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/10/2012
Entry Details Article
PubMed
TargetBeta-secretase 1(Human)
Eli Lilly

Curated by ChEMBL
LigandPNGBDBM50137680({(S)-1-[(S)-1-((2S,4S)-1-Benzyl-2-hydroxy-4-{(R)-2...)
Affinity DataIC50: 281nMAssay Description:In vitro inhibition of Beta-secretase-1 in HEK293 (Human Embryonic Kidney) cell line.More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/10/2012
Entry Details Article
PubMed
TargetBeta-secretase 1(Human)
Eli Lilly

Curated by ChEMBL
LigandPNGBDBM50137692({(S)-1-[(S)-1-((2S,4S)-1-Benzyl-2-hydroxy-4-{(R)-2...)
Affinity DataIC50: 419nMAssay Description:In vitro inhibition of Beta-secretase-1 in HEK293 (Human Embryonic Kidney) cell line.More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/10/2012
Entry Details Article
PubMed
TargetBeta-secretase 2(Human)
Eli Lilly

Curated by ChEMBL
LigandPNGBDBM16250(CHEMBL290001 | tert-butyl N-[(1S)-1-{[(1S)-1-{[(1R...)
Affinity DataIC50: 500nMAssay Description:Selectivity tested against Beta-secretase 2 (BACE) in humanMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/10/2012
Entry Details Article
PubMed
TargetBeta-secretase 1(Human)
Eli Lilly

Curated by ChEMBL
LigandPNGBDBM50137687({(S)-1-[(S)-1-((2S,4S)-1-Benzyl-2-hydroxy-4-{(R)-2...)
Affinity DataIC50: 705nMAssay Description:In vitro inhibition of Beta-secretase-1 in HEK293 (Human Embryonic Kidney) cell line.More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/10/2012
Entry Details Article
PubMed
TargetBeta-secretase 1(Human)
Eli Lilly

Curated by ChEMBL
LigandPNGBDBM50451850(CHEMBL2114169)
Affinity DataIC50: 1.06E+3nMAssay Description:In vitro inhibition of Beta-secretase-1 in HEK293 (Human Embryonic Kidney) cell line.More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/10/2012
Entry Details Article
PubMed
TargetBeta-secretase 1(Human)
Eli Lilly

Curated by ChEMBL
LigandPNGBDBM16047(EVNXXAEF | N-{(2R,4S,5S)-5-[(L-alpha-glutamyl-L-va...)
Affinity DataKi:  1.60E+3nMAssay Description:Binding affinity towards Beta-secretase 1 expressed in HEK293 (Human Embryonic Kidney) cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/10/2012
Entry Details Article
PubMed
TargetBeta-secretase 1(Human)
Eli Lilly

Curated by ChEMBL
LigandPNGBDBM50137679({(S)-1-[(S)-1-((2S,4S)-1-Benzyl-2-hydroxy-4-{(R)-2...)
Affinity DataIC50: 2.53E+3nMAssay Description:In vitro inhibition of Beta-secretase-1 in HEK293 (Human Embryonic Kidney) cell line.More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/10/2012
Entry Details Article
PubMed
TargetBeta-secretase 1(Human)
Eli Lilly

Curated by ChEMBL
LigandPNGBDBM50137689({(S)-1-[(S)-1-((2S,4S)-1-Benzyl-2-hydroxy-4-{(R)-2...)
Affinity DataIC50: 8.90E+4nMAssay Description:In vitro inhibition of Beta-secretase-1 in HEK293 (Human Embryonic Kidney) cell line.More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/10/2012
Entry Details Article
PubMed