Compile Data Set for Download or QSAR
Report error Found 24 Enz. Inhib. hit(s) with all data for entry = 996
LigandPNGBDBM7965(1,4-bis-(imidazol-1-yl)methyl-2,5-dimethylbenzene ...)
Affinity DataKi:  295nMAssay Description:QC activity was evaluated fluorometrically using Gln-AMC as substrate, and pyroglutamyl peptidase as the auxiliary enzyme. After conversion of Gln-AM...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/28/2006
Entry Details Article
PubMed
LigandPNGBDBM7963(1-(4-chlorophenyl)-3-[2-(1H-imidazol-1-yl)ethyl]th...)
Affinity DataKi:  1.20E+3nMAssay Description:QC activity was evaluated fluorometrically using Gln-AMC as substrate, and pyroglutamyl peptidase as the auxiliary enzyme. After conversion of Gln-AM...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/28/2006
Entry Details Article
PubMed
LigandPNGBDBM7962(CHEMBL537708 | 4-[2-(1H-imidazol-1-yl)ethoxy]benzo...)
Affinity DataKi:  2.30E+3nMAssay Description:QC activity was evaluated fluorometrically using Gln-AMC as substrate, and pyroglutamyl peptidase as the auxiliary enzyme. After conversion of Gln-AM...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/28/2006
Entry Details Article
PubMed
LigandPNGBDBM7961(1-(6-phenoxyhexyl)-1H-imidazole | Imidazole N-1 de...)
Affinity DataKi:  6.20E+3nMAssay Description:QC activity was evaluated fluorometrically using Gln-AMC as substrate, and pyroglutamyl peptidase as the auxiliary enzyme. After conversion of Gln-AM...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/28/2006
Entry Details Article
PubMed
LigandPNGBDBM7949(N-[2-(1H-Imidazol-4-yl)ethyl]acetamide | N-omega-A...)
Affinity DataKi:  1.70E+4nM ΔG°:  -27.7kJ/molepH: 8.0 T: 2°CAssay Description:QC activity was evaluated fluorometrically using Gln-AMC as substrate, and pyroglutamyl peptidase as the auxiliary enzyme. After conversion of Gln-AM...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/28/2006
Entry Details Article
PubMed
LigandPNGBDBM7942(1-ethenyl-1H-imidazole | 1-Subsituted 1H-imidazole...)
Affinity DataKi:  4.90E+4nM ΔG°:  -25.0kJ/molepH: 8.0 T: 2°CAssay Description:QC activity was evaluated fluorometrically using Gln-AMC as substrate, and pyroglutamyl peptidase as the auxiliary enzyme. After conversion of Gln-AM...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/28/2006
Entry Details Article
PubMed
LigandPNGBDBM7944(N-Acetylimidazole | 1-(1H-imidazol-1-yl)ethan-1-on...)
Affinity DataKi:  1.07E+5nM ΔG°:  -23.0kJ/molepH: 8.0 T: 2°CAssay Description:QC activity was evaluated fluorometrically using Gln-AMC as substrate, and pyroglutamyl peptidase as the auxiliary enzyme. After conversion of Gln-AM...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/28/2006
Entry Details Article
PubMed
LigandPNGBDBM7967(CHEMBL14722 | 2-(1-methyl-1H-imidazol-5-yl)ethan-1...)
Affinity DataKi:  1.20E+5nMAssay Description:QC activity was evaluated fluorometrically using Gln-AMC as substrate, and pyroglutamyl peptidase as the auxiliary enzyme. After conversion of Gln-AM...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/28/2006
Entry Details Article
PubMed
LigandPNGBDBM7956((4-methyl-1H-imidazol-5-yl)methanol | 5-Hydroxymet...)
Affinity DataKi:  1.29E+5nMAssay Description:QC activity was evaluated fluorometrically using Gln-AMC as substrate, and pyroglutamyl peptidase as the auxiliary enzyme. After conversion of Gln-AM...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/28/2006
Entry Details Article
PubMed
LigandPNGBDBM7939(1H-1,3-benzodiazole | Benzimidazole | Benzimidazol...)
Affinity DataKi:  1.38E+5nM ΔG°:  -22.4kJ/molepH: 8.0 T: 2°CAssay Description:QC activity was evaluated fluorometrically using Gln-AMC as substrate, and pyroglutamyl peptidase as the auxiliary enzyme. After conversion of Gln-AM...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/28/2006
Entry Details Article
PubMed
LigandPNGBDBM7945(N-(Trimethylsilyl)-imidazole | 1-(trimethylsilyl)-...)
Affinity DataKi:  1.67E+5nM ΔG°:  -21.9kJ/molepH: 8.0 T: 2°CAssay Description:QC activity was evaluated fluorometrically using Gln-AMC as substrate, and pyroglutamyl peptidase as the auxiliary enzyme. After conversion of Gln-AM...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/28/2006
Entry Details Article
PubMed
LigandPNGBDBM7946(N-Benzoylimidazole | 1-benzoyl-1H-imidazole | Imid...)
Affinity DataKi:  1.74E+5nM ΔG°:  -21.8kJ/molepH: 8.0 T: 2°CAssay Description:QC activity was evaluated fluorometrically using Gln-AMC as substrate, and pyroglutamyl peptidase as the auxiliary enzyme. After conversion of Gln-AM...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/28/2006
Entry Details Article
PubMed
LigandPNGBDBM7947(1-(2-Oxo-2-phenylethyl)-imidazole | 2-(1H-imidazol...)
Affinity DataKi:  1.84E+5nM ΔG°:  -21.7kJ/molepH: 8.0 T: 2°CAssay Description:QC activity was evaluated fluorometrically using Gln-AMC as substrate, and pyroglutamyl peptidase as the auxiliary enzyme. After conversion of Gln-AM...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/28/2006
Entry Details Article
PubMed
LigandPNGBDBM7948(1-(3-Aminopropyl)-imidazole | 3-(1H-imidazol-1-yl)...)
Affinity DataKi:  4.10E+5nM ΔG°:  -19.7kJ/molepH: 8.0 T: 2°CAssay Description:QC activity was evaluated fluorometrically using Gln-AMC as substrate, and pyroglutamyl peptidase as the auxiliary enzyme. After conversion of Gln-AM...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/28/2006
Entry Details Article
PubMed
LigandPNGBDBM7950(L-Histidinamide | (2S)-2-amino-3-(1H-imidazol-4-yl...)
Affinity DataKi:  5.60E+5nM ΔG°:  -18.9kJ/molepH: 8.0 T: 2°CAssay Description:QC activity was evaluated fluorometrically using Gln-AMC as substrate, and pyroglutamyl peptidase as the auxiliary enzyme. After conversion of Gln-AM...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/28/2006
Entry Details Article
PubMed
LigandPNGBDBM7959(2-ethyl-4-methyl-1H-imidazole | 2-Ethyl-4-methyl-i...)
Affinity DataKi:  5.80E+5nMAssay Description:QC activity was evaluated fluorometrically using Gln-AMC as substrate, and pyroglutamyl peptidase as the auxiliary enzyme. After conversion of Gln-AM...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/28/2006
Entry Details Article
PubMed
LigandPNGBDBM7951(H-His-Trp-OH | 2-[2-amino-3-(1H-imidazol-4-yl)prop...)
Affinity DataKi:  6.00E+5nM ΔG°:  -18.7kJ/molepH: 8.0 T: 2°CAssay Description:QC activity was evaluated fluorometrically using Gln-AMC as substrate, and pyroglutamyl peptidase as the auxiliary enzyme. After conversion of Gln-AM...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/28/2006
Entry Details Article
PubMed
LigandPNGBDBM7966([3H]histamine | 2-(1H-imidazol-4-yl)ethan-1-amine ...)
Affinity DataKi:  8.50E+5nMAssay Description:QC activity was evaluated fluorometrically using Gln-AMC as substrate, and pyroglutamyl peptidase as the auxiliary enzyme. After conversion of Gln-AM...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/28/2006
Entry Details Article
PubMed
LigandPNGBDBM7952((2S)-2-amino-3-(1H-imidazol-4-yl)propan-1-ol | L-H...)
Affinity DataKi:  1.53E+6nM ΔG°:  -16.3kJ/molepH: 8.0 T: 2°CAssay Description:QC activity was evaluated fluorometrically using Gln-AMC as substrate, and pyroglutamyl peptidase as the auxiliary enzyme. After conversion of Gln-AM...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/28/2006
Entry Details Article
PubMed
LigandPNGBDBM7960(CHEMBL305513 | JMC524454 Compound 5 | 1H-1,3-benzo...)
Affinity DataKi:  1.80E+6nMAssay Description:QC activity was evaluated fluorometrically using Gln-AMC as substrate, and pyroglutamyl peptidase as the auxiliary enzyme. After conversion of Gln-AM...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/28/2006
Entry Details Article
PubMed
LigandPNGBDBM7953(L-2-Amino-3-(4-imidazolyl)propionic acid | (2S)-2-...)
Affinity DataKi:  4.40E+6nMAssay Description:QC activity was evaluated fluorometrically using Gln-AMC as substrate, and pyroglutamyl peptidase as the auxiliary enzyme. After conversion of Gln-AM...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/28/2006
Entry Details Article
PubMed
LigandPNGBDBM7954(Imidazole-4-carboxaldehyde | 1H-imidazole-4-carbal...)
Affinity DataKi:  7.60E+6nMAssay Description:QC activity was evaluated fluorometrically using Gln-AMC as substrate, and pyroglutamyl peptidase as the auxiliary enzyme. After conversion of Gln-AM...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/28/2006
Entry Details Article
PubMed
LigandPNGBDBM7955(Imidazol-4-carbonic acid methylester | methyl 1H-i...)
Affinity DataKi:  1.45E+7nMAssay Description:QC activity was evaluated fluorometrically using Gln-AMC as substrate, and pyroglutamyl peptidase as the auxiliary enzyme. After conversion of Gln-AM...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/28/2006
Entry Details Article
PubMed
LigandPNGBDBM7957(5-Amino-3H-imidazole-4-carboxylic acid amide | 4-a...)
Affinity DataKi:  1.55E+7nMAssay Description:QC activity was evaluated fluorometrically using Gln-AMC as substrate, and pyroglutamyl peptidase as the auxiliary enzyme. After conversion of Gln-AM...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/28/2006
Entry Details Article
PubMed