Compile Data Set for Download or QSAR
Report error Found 23 Enz. Inhib. hit(s) with all data for entry = 50036110
TargetNeprilysin(Human)
University of Paris

Curated by ChEMBL
LigandPNGBDBM50002022(CHEMBL16779 | (2-Benzyl-3-hydroxycarbamoyl-propion...)
Affinity DataIC50: 1.40nMAssay Description:Inhibitory potency against neutral endopeptidaseMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/24/2012
Entry Details Article
PubMed
TargetNeprilysin(Human)
University of Paris

Curated by ChEMBL
LigandPNGBDBM50002018(CHEMBL442337 | 2-(2-Mercaptomethyl-3-phenyl-propio...)
Affinity DataIC50: 4.5nMAssay Description:Inhibitory potency against neutral endopeptidaseMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/24/2012
Entry Details Article
PubMed
TargetAminopeptidase N(Pig)
University of Paris

Curated by ChEMBL
LigandPNGBDBM50002031(1-Mercaptomethyl-3-methylsulfanyl-propyl-ammonium)
Affinity DataIC50: 11nMAssay Description:Inhibition of [3H]Leu-enkephalin binding to Aminopeptidase N from hog kidneyMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/24/2012
Entry Details Article
PubMed
TargetNeprilysin(Human)
University of Paris

Curated by ChEMBL
LigandPNGBDBM50002035(CHEMBL17107 | (2-Hydroxycarbamoyl-3-phenyl-propion...)
Affinity DataIC50: 15nMAssay Description:Inhibitory potency against neutral endopeptidaseMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/24/2012
Entry Details Article
PubMed
TargetAminopeptidase N(Pig)
University of Paris

Curated by ChEMBL
LigandPNGBDBM50002026(2-Mercapto-1-methylsulfanylmethyl-ethyl-ammonium)
Affinity DataIC50: 20nMAssay Description:Inhibition of [3H]Leu-enkephalin binding to Aminopeptidase N from hog kidneyMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/24/2012
Entry Details Article
PubMed
TargetAminopeptidase N(Pig)
University of Paris

Curated by ChEMBL
LigandPNGBDBM50368599(CHEMBL1159809)
Affinity DataIC50: 20nMAssay Description:Inhibition of [3H]Leu-enkephalin binding to Aminopeptidase N from hog kidneyMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/24/2012
Entry Details Article
PubMed
TargetAminopeptidase N(Pig)
University of Paris

Curated by ChEMBL
LigandPNGBDBM50368598(CHEMBL1159810)
Affinity DataIC50: 21nMAssay Description:Inhibition of [3H]Leu-enkephalin binding to Aminopeptidase N from hog kidneyMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/24/2012
Entry Details Article
PubMed
TargetAminopeptidase N(Pig)
University of Paris

Curated by ChEMBL
LigandPNGBDBM50002027(1-Mercaptomethyl-3-methyl-butyl-ammonium)
Affinity DataIC50: 22nMAssay Description:Inhibition of [3H]Leu-enkephalin binding to Aminopeptidase N from hog kidneyMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/24/2012
Entry Details Article
PubMed
TargetAminopeptidase N(Pig)
University of Paris

Curated by ChEMBL
LigandPNGBDBM50002034(2-Mercapto-1-phenyl-ethyl-ammonium)
Affinity DataIC50: 25nMAssay Description:Compound was tested for inhibitory potency against aminopeptidase N from hog kidney, using [3H]Leu-enkephalin as substrateMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/24/2012
Entry Details Article
PubMed
TargetAminopeptidase N(Pig)
University of Paris

Curated by ChEMBL
LigandPNGBDBM50036828(1-Mercaptomethyl-2-phenyl-ethyl-ammonium | 2-Amino...)
Affinity DataIC50: 30nMAssay Description:Compound was tested for inhibitory potency against aminopeptidase N from hog kidney, using [3H]Leu-enkephalin as substrateMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/24/2012
Entry Details Article
PubMed
TargetAminopeptidase N(Pig)
University of Paris

Curated by ChEMBL
LigandPNGBDBM50002019(2-tert-Butylsulfanyl-1-mercaptomethyl-ethyl-ammoni...)
Affinity DataIC50: 40nMAssay Description:Inhibition of [3H]Leu-enkephalin binding to Aminopeptidase N from hog kidneyMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/24/2012
Entry Details Article
PubMed
TargetAminopeptidase N(Pig)
University of Paris

Curated by ChEMBL
LigandPNGBDBM50002030(2-Cyclohexyl-1-mercaptomethyl-ethyl-ammonium)
Affinity DataIC50: 45nMAssay Description:Compound was tested for inhibitory potency against aminopeptidase N from hog kidney, using [3H]Leu-enkephalin as substrateMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/24/2012
Entry Details Article
PubMed
TargetAminopeptidase N(Pig)
University of Paris

Curated by ChEMBL
LigandPNGBDBM50002037(2-(4-Hydroxy-phenyl)-1-mercaptomethyl-ethyl-ammoni...)
Affinity DataIC50: 45nMAssay Description:Compound was tested for inhibitory potency against aminopeptidase N from hog kidney, using [3H]Leu-enkephalin as substrateMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/24/2012
Entry Details Article
PubMed
TargetNeprilysin(Human)
University of Paris

Curated by ChEMBL
LigandPNGBDBM50002038(CHEMBL25432 | 2-(2-Mercapto-3-phenyl-propionylamin...)
Affinity DataIC50: 50nMAssay Description:Inhibitory potency against neutral endopeptidaseMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/24/2012
Entry Details Article
PubMed
TargetAminopeptidase N(Pig)
University of Paris

Curated by ChEMBL
LigandPNGBDBM50002028(1-Benzyloxymethyl-2-mercapto-ethyl-ammonium)
Affinity DataIC50: 56nMAssay Description:Inhibition of [3H]Leu-enkephalin binding to Aminopeptidase N from hog kidneyMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/24/2012
Entry Details Article
PubMed
TargetAminopeptidase N(Pig)
University of Paris

Curated by ChEMBL
LigandPNGBDBM50002020(2-Benzylsulfanyl-1-mercaptomethyl-ethyl-ammonium)
Affinity DataIC50: 90nMAssay Description:Inhibition of [3H]Leu-enkephalin binding to Aminopeptidase N from hog kidneyMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/24/2012
Entry Details Article
PubMed
TargetAminopeptidase N(Pig)
University of Paris

Curated by ChEMBL
LigandPNGBDBM50002017(1-Mercaptomethyl-2-naphthalen-2-yl-ethyl-ammonium)
Affinity DataIC50: 130nMAssay Description:Inhibition of [3H]Leu-enkephalin binding to Aminopeptidase N from hog kidneyMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/24/2012
Entry Details Article
PubMed
TargetAminopeptidase N(Pig)
University of Paris

Curated by ChEMBL
LigandPNGBDBM50002024((1-Mercaptomethyl-3-methyl-butyl)-methyl-ammonium)
Affinity DataIC50: 4.00E+3nMAssay Description:Inhibition of [3H]Leu-enkephalin binding to Aminopeptidase N from hog kidneyMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/24/2012
Entry Details Article
PubMed
TargetAminopeptidase N(Pig)
University of Paris

Curated by ChEMBL
LigandPNGBDBM50036826(1-Benzyl-2-hydroxycarbamoyl-ethyl-ammonium | 3-Ami...)
Affinity DataIC50: 7.50E+4nMAssay Description:Inhibition of [3H]Leu-enkephalin binding to Aminopeptidase N from hog kidneyMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/24/2012
Entry Details Article
PubMed
TargetAminopeptidase N(Pig)
University of Paris

Curated by ChEMBL
LigandPNGBDBM50002033(1-Benzylsulfanylmethyl-2-phenyl-ethyl-ammonium)
Affinity DataIC50: 8.00E+4nMAssay Description:Inhibition of [3H]Leu-enkephalin binding to Aminopeptidase N from hog kidneyMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/24/2012
Entry Details Article
PubMed
TargetAminopeptidase N(Pig)
University of Paris

Curated by ChEMBL
LigandPNGBDBM50002029(Benzyl-(1-mercaptomethyl-2-phenyl-ethyl)-ammonium)
Affinity DataIC50: 1.60E+5nMAssay Description:Inhibition of [3H]Leu-enkephalin binding to Aminopeptidase N from hog kidneyMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/24/2012
Entry Details Article
PubMed
TargetAminopeptidase N(Pig)
University of Paris

Curated by ChEMBL
LigandPNGBDBM50036832(1-Benzyl-2-phosphono-ethyl-ammonium | (2-Amino-3-p...)
Affinity DataIC50: 5.00E+5nMAssay Description:Inhibition of [3H]Leu-enkephalin binding to Aminopeptidase N from hog kidneyMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/24/2012
Entry Details Article
PubMed
TargetAminopeptidase N(Pig)
University of Paris

Curated by ChEMBL
LigandPNGBDBM50036830(3-Amino-4-phenyl-butyric acid | 1-Benzyl-2-carboxy...)
Affinity DataIC50: 8.00E+5nMAssay Description:Compound was tested for inhibitory potency against aminopeptidase N from hog kidney, using [3H]Leu-enkephalin as substrateMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/24/2012
Entry Details Article
PubMed