Compile Data Set for Download or QSAR
Report error Found 14 Enz. Inhib. hit(s) with all data for entry = 50000021
TargetcGMP-inhibited 3',5'-cyclic phosphodiesterase 3A/3B(Human)
Syntex Research

Curated by ChEMBL
LigandPNGBDBM50000334(Agrylin | 6,7-Dichloro-1,5-dihydro-imidazo[2,1-b]q...)
Affinity DataIC50: 82nMAssay Description:Inhibition of human blood platelet c-AMP phosphodiesteraseMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMedPDB3D3D Structure (crystal)
TargetThromboxane-A synthase(Human)
Syntex Research

Curated by ChEMBL
LigandPNGBDBM50000308(CHEMBL158201 | 6-(Imidazol-1-yl-phenyl-methyl)-3,4...)
Affinity DataIC50: 350nMAssay Description:Compound was evaluated for the inhibition of human blood platelet,thromboxane A2 synthaseMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetThromboxane-A synthase(Human)
Syntex Research

Curated by ChEMBL
LigandPNGBDBM50000318(CHEMBL347379 | 6-(2-Imidazol-1-yl-vinyl)-1H-quinol...)
Affinity DataIC50: 380nMAssay Description:Compound was evaluated for the inhibition of human blood platelet,thromboxane A2 synthaseMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetThromboxane-A synthase(Human)
Syntex Research

Curated by ChEMBL
LigandPNGBDBM50000306(6-Pyridin-3-yl-3,4-dihydro-1H-quinolin-2-one | CHE...)
Affinity DataIC50: 540nMAssay Description:Compound was evaluated for the inhibition of human blood platelet,thromboxane A2 synthaseMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetThromboxane-A synthase(Human)
Syntex Research

Curated by ChEMBL
LigandPNGBDBM50000310(CHEMBL160790 | 6-(2-Imidazol-1-yl-vinyl)-3,4-dihyd...)
Affinity DataIC50: 1.20E+3nMAssay Description:Compound was evaluated for the inhibition of human blood platelet thromboxane A2 synthaseMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetThromboxane-A synthase(Human)
Syntex Research

Curated by ChEMBL
LigandPNGBDBM50000309(CHEMBL17516 | 6-Imidazol-1-yl-3,4-dihydro-1H-quino...)
Affinity DataIC50: 2.00E+3nMAssay Description:Compound was evaluated for the inhibition of human blood platelet,thromboxane A2 synthaseMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetcGMP-inhibited 3',5'-cyclic phosphodiesterase 3A/3B(Human)
Syntex Research

Curated by ChEMBL
LigandPNGBDBM50000318(CHEMBL347379 | 6-(2-Imidazol-1-yl-vinyl)-1H-quinol...)
Affinity DataIC50: 4.00E+3nMAssay Description:Inhibition of human blood platelet c-AMP phosphodiesteraseMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetcGMP-inhibited 3',5'-cyclic phosphodiesterase 3A/3B(Human)
Syntex Research

Curated by ChEMBL
LigandPNGBDBM50000306(6-Pyridin-3-yl-3,4-dihydro-1H-quinolin-2-one | CHE...)
Affinity DataIC50: 4.40E+3nMAssay Description:Inhibition of human blood platelet c-AMP phosphodiesteraseMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetcGMP-inhibited 3',5'-cyclic phosphodiesterase 3A/3B(Human)
Syntex Research

Curated by ChEMBL
LigandPNGBDBM50000315((CI-914)6-(4-Imidazol-1-yl-phenyl)-4,5-dihydro-2H-...)
Affinity DataIC50: 4.70E+3nMAssay Description:Inhibition of human blood platelet c-AMP phosphodiesteraseMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetcGMP-inhibited 3',5'-cyclic phosphodiesterase 3A/3B(Human)
Syntex Research

Curated by ChEMBL
LigandPNGBDBM50000310(CHEMBL160790 | 6-(2-Imidazol-1-yl-vinyl)-3,4-dihyd...)
Affinity DataIC50: 6.40E+3nMAssay Description:Inhibition of human blood platelet c-AMP phosphodiesteraseMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetcGMP-inhibited 3',5'-cyclic phosphodiesterase 3A/3B(Human)
Syntex Research

Curated by ChEMBL
LigandPNGBDBM50000328(CHEMBL157346 | 6-(1-Imidazol-1-ylmethyl-hexyl)-3,4...)
Affinity DataIC50: 1.40E+4nMAssay Description:Inhibition of human blood platelet c-AMP phosphodiesteraseMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetcGMP-inhibited 3',5'-cyclic phosphodiesterase 3A/3B(Human)
Syntex Research

Curated by ChEMBL
LigandPNGBDBM50000309(CHEMBL17516 | 6-Imidazol-1-yl-3,4-dihydro-1H-quino...)
Affinity DataIC50: 1.60E+4nMAssay Description:Inhibition of human blood platelet c-AMP phosphodiesteraseMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetThromboxane-A synthase(Human)
Syntex Research

Curated by ChEMBL
LigandPNGBDBM50000328(CHEMBL157346 | 6-(1-Imidazol-1-ylmethyl-hexyl)-3,4...)
Affinity DataIC50: 2.50E+4nMAssay Description:Compound was evaluated for the inhibition of human blood platelet thromboxane A2 synthaseMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetcGMP-inhibited 3',5'-cyclic phosphodiesterase 3A/3B(Human)
Syntex Research

Curated by ChEMBL
LigandPNGBDBM50000308(CHEMBL158201 | 6-(Imidazol-1-yl-phenyl-methyl)-3,4...)
Affinity DataIC50: 4.00E+4nMAssay Description:Inhibition of human blood platelet c-AMP phosphodiesteraseMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed