Compile Data Set for Download or QSAR
Report error Found 38 Enz. Inhib. hit(s) with all data for entry = 50000018
TargetKappa-type opioid receptor(Human)
Glaxo Group Research

Curated by ChEMBL
LigandPNGBDBM50000293(2-(3,4-Dichloro-phenyl)-1-(7-pyrrolidin-1-ylmethyl...)
Affinity DataIC50: 0.100nMAssay Description:Kappa-opioid receptor agonist potency in vitro using rabbit vas deferens(LVD) preparationMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetKappa-type opioid receptor(Human)
Glaxo Group Research

Curated by ChEMBL
LigandPNGBDBM50000288(CHEMBL343858 | (1-{1-[2-(3,4-Dichloro-phenyl)-acet...)
Affinity DataIC50: 0.120nMAssay Description:Opioid receptor kappa 1 agonist potency of the compound was determined in vitro using rabbit vas deferens(LVD) preparationMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetKappa-type opioid receptor(Human)
Glaxo Group Research

Curated by ChEMBL
LigandPNGBDBM50000271(CHEMBL146519 | 1-{1-[2-(3,4-Dichloro-phenyl)-acety...)
Affinity DataIC50: 0.200nMAssay Description:Opioid receptor kappa 1 agonist potency of the compound was determined in vitro using rabbit vas deferens(LVD) preparationMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetKappa-type opioid receptor(Human)
Glaxo Group Research

Curated by ChEMBL
LigandPNGBDBM50000260(CHEMBL148219 | 2-(3,4-Dichloro-phenyl)-1-[2-(3-hyd...)
Affinity DataIC50: 0.880nMAssay Description:Opioid receptor kappa agonist potency was determined in vitro using rabbit vas deferens(LVD) preparationMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetKappa-type opioid receptor(Human)
Glaxo Group Research

Curated by ChEMBL
LigandPNGBDBM50000284(CHEMBL148083 | 2-(3,4-Dichloro-phenyl)-1-(2-methyl...)
Affinity DataIC50: 1.70nMAssay Description:Opioid receptor kappa agonist potency was determined in vitro using rabbit vas deferens(LVD) preparationMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetKappa-type opioid receptor(Human)
Glaxo Group Research

Curated by ChEMBL
LigandPNGBDBM50000292(CHEMBL343246 | 2-(3,4-Dichloro-phenyl)-1-[2-(2,5-d...)
Affinity DataIC50: 3.5nMAssay Description:Opioid receptor kappa 1 agonist potency of the compound was determined in vitro using rabbit vas deferens(LVD) preparationMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetKappa-type opioid receptor(Human)
Glaxo Group Research

Curated by ChEMBL
LigandPNGBDBM50000274(CHEMBL357297 | (1-{1-[2-(3,4-Dichloro-phenyl)-acet...)
Affinity DataIC50: 4.70nMAssay Description:Opioid receptor kappa agonist potency was determined in vitro using rabbit vas deferens(LVD) preparationMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetKappa-type opioid receptor(Human)
Glaxo Group Research

Curated by ChEMBL
LigandPNGBDBM50000286(CHEMBL149668 | 2-(3,4-Dichloro-phenyl)-1-(7-pyrrol...)
Affinity DataIC50: 5nMAssay Description:Opioid receptor kappa agonist potency was determined in vitro using rabbit vas deferens(LVD) preparationMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetKappa-type opioid receptor(Human)
Glaxo Group Research

Curated by ChEMBL
LigandPNGBDBM50000297(CHEMBL344342 | 2-(3,4-Dichloro-phenyl)-1-[2-(3,6-d...)
Affinity DataIC50: 6.30nMAssay Description:Kappa-opioid receptor agonist potency in vitro using rabbit vas deferens(LVD) preparationMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetKappa-type opioid receptor(Human)
Glaxo Group Research

Curated by ChEMBL
LigandPNGBDBM50000287(CHEMBL128444 | 2-(3,4-Dichloro-phenyl)-1-(2-pyrrol...)
Affinity DataIC50: 11nMAssay Description:Kappa-opioid receptor agonist potency of the compound was determined in vitro using rabbit vas deferens(LVD) preparationMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetKappa-type opioid receptor(Human)
Glaxo Group Research

Curated by ChEMBL
LigandPNGBDBM50000285(CHEMBL144483 | 1-{1-[2-(3,4-Dichloro-phenyl)-acety...)
Affinity DataIC50: 15nMAssay Description:Kappa-opioid receptor agonist potency in vitro using rabbit vas deferens(LVD) preparationMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetKappa-type opioid receptor(Human)
Glaxo Group Research

Curated by ChEMBL
LigandPNGBDBM50000273(CHEMBL146612 | 2-(3,4-Dichloro-phenyl)-1-[2-(3-met...)
Affinity DataIC50: 29nMAssay Description:Opioid receptor kappa agonist potency was determined in vitro using rabbit vas deferens(LVD) preparationMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetKappa-type opioid receptor(Human)
Glaxo Group Research

Curated by ChEMBL
LigandPNGBDBM50000275(CHEMBL146884 | 1-[2-(3,4-Dichloro-phenyl)-acetyl]-...)
Affinity DataIC50: 46nMAssay Description:Opioid receptor kappa agonist potency was determined in vitro using rabbit vas deferens(LVD) preparationMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetKappa-type opioid receptor(Human)
Glaxo Group Research

Curated by ChEMBL
LigandPNGBDBM50000272(CHEMBL147651 | 2-(3,4-Dichloro-phenyl)-1-(2-methyl...)
Affinity DataIC50: 57nMAssay Description:Opioid receptor kappa agonist potency was determined in vitro using rabbit vas deferens(LVD) preparationMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetKappa-type opioid receptor(Human)
Glaxo Group Research

Curated by ChEMBL
LigandPNGBDBM50000282(CHEMBL146413 | 2-(3,4-Dichloro-phenyl)-1-(2-isoxaz...)
Affinity DataIC50: 69nMAssay Description:Kappa-opioid receptor agonist potency in vitro using rabbit vas deferens(LVD) preparationMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetKappa-type opioid receptor(Human)
Glaxo Group Research

Curated by ChEMBL
LigandPNGBDBM50000267(2-(3,4-Dichloro-phenyl)-1-(2-dimethylaminomethyl-p...)
Affinity DataIC50: 102nMAssay Description:Opioid receptor kappa 1 agonist potency of the compound was determined in vitro using rabbit vas deferens(LVD) preparationMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetKappa-type opioid receptor(Human)
Glaxo Group Research

Curated by ChEMBL
LigandPNGBDBM50000289(CHEMBL146555 | 1-[2-(3,4-Dichloro-phenyl)-acetyl]-...)
Affinity DataIC50: 110nMAssay Description:Kappa-opioid receptor agonist potency in vitro using rabbit vas deferens(LVD) preparationMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetKappa-type opioid receptor(Human)
Glaxo Group Research

Curated by ChEMBL
LigandPNGBDBM50000295(CHEMBL342965 | 2-(3,4-Dichloro-phenyl)-1-(4-hydrox...)
Affinity DataIC50: 120nMAssay Description:Opioid receptor kappa 1 agonist potency of the compound was determined in vitro using rabbit vas deferens(LVD) preparationMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetKappa-type opioid receptor(Human)
Glaxo Group Research

Curated by ChEMBL
LigandPNGBDBM50000263(CHEMBL358727 | 2-(3,4-Dichloro-phenyl)-1-(8-pyrrol...)
Affinity DataIC50: 160nMAssay Description:Kappa-opioid receptor agonist potency in vitro using rabbit vas deferens(LVD) preparationMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetKappa-type opioid receptor(Human)
Glaxo Group Research

Curated by ChEMBL
LigandPNGBDBM50000268(CHEMBL359252 | 1-[2-(3,4-Dichloro-phenyl)-acetyl]-...)
Affinity DataIC50: 250nMAssay Description:Opioid receptor kappa agonist potency was determined in vitro using rabbit vas deferens(LVD) preparationMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetKappa-type opioid receptor(Human)
Glaxo Group Research

Curated by ChEMBL
LigandPNGBDBM50000278(CHEMBL131328 | 2-(3,4-Dichloro-phenyl)-1-(2-piperi...)
Affinity DataIC50: 260nMAssay Description:Opioid receptor kappa agonist potency was determined in vitro using rabbit vas deferens(LVD) preparationMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetKappa-type opioid receptor(Human)
Glaxo Group Research

Curated by ChEMBL
LigandPNGBDBM50000269(CHEMBL345513 | 1-[2-(3,4-Dichloro-phenyl)-acetyl]-...)
Affinity DataIC50: 300nMAssay Description:Kappa-opioid receptor agonist potency in vitro using rabbit vas deferens(LVD) preparationMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetKappa-type opioid receptor(Human)
Glaxo Group Research

Curated by ChEMBL
LigandPNGBDBM50000296(CHEMBL441765 | CHEMBL482811 | U-50488H | US1149237...)
Affinity DataIC50: 370nMAssay Description:Opioid receptor kappa agonist potency was determined in vitro using rabbit vas deferens(LVD) preparationMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetKappa-type opioid receptor(Human)
Glaxo Group Research

Curated by ChEMBL
LigandPNGBDBM50000283(CHEMBL344541 | 1-[2-(3,4-Dichloro-phenyl)-acetyl]-...)
Affinity DataIC50: 390nMAssay Description:Kappa-opioid receptor agonist potency in vitro using rabbit vas deferens(LVD) preparationMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetKappa-type opioid receptor(Human)
Glaxo Group Research

Curated by ChEMBL
LigandPNGBDBM50000280(CHEMBL148117 | 2-(3,4-Dichloro-phenyl)-1-[2-(4-met...)
Affinity DataIC50: 550nMAssay Description:Opioid receptor kappa 1 agonist potency of the compound was determined in vitro using rabbit vas deferens(LVD) preparationMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetKappa-type opioid receptor(Human)
Glaxo Group Research

Curated by ChEMBL
LigandPNGBDBM50000270(CHEMBL146632 | 2-(3,4-Dichloro-phenyl)-1-(3-hydrox...)
Affinity DataIC50: 590nMAssay Description:Opioid receptor kappa agonist potency was determined in vitro using rabbit vas deferens(LVD) preparationMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetKappa-type opioid receptor(Human)
Glaxo Group Research

Curated by ChEMBL
LigandPNGBDBM50000276(CHEMBL343661 | (1-{1-[2-(3,4-Dichloro-phenyl)-acet...)
Affinity DataIC50: 690nMAssay Description:Opioid receptor kappa 1 agonist potency of the compound was determined in vitro using rabbit vas deferens(LVD) preparationMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetKappa-type opioid receptor(Human)
Glaxo Group Research

Curated by ChEMBL
LigandPNGBDBM50000264(CHEMBL147275 | 2-(3,4-Dichloro-phenyl)-1-(3-hydrox...)
Affinity DataIC50: 970nMAssay Description:Opioid receptor kappa agonist potency was determined in vitro using rabbit vas deferens(LVD) preparationMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetKappa-type opioid receptor(Human)
Glaxo Group Research

Curated by ChEMBL
LigandPNGBDBM50000265(CHEMBL146682 | (1-{1-[2-(3,4-Dichloro-phenyl)-acet...)
Affinity DataIC50: 1.02E+3nMAssay Description:Opioid receptor kappa agonist potency was determined in vitro using rabbit vas deferens(LVD) preparationMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetKappa-type opioid receptor(Human)
Glaxo Group Research

Curated by ChEMBL
LigandPNGBDBM50000262(CHEMBL146140 | 1-[2-(3,4-Dichloro-phenyl)-acetyl]-...)
Affinity DataIC50: 1.20E+3nMAssay Description:Kappa-opioid receptor agonist potency in vitro using rabbit vas deferens(LVD) preparationMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetKappa-type opioid receptor(Human)
Glaxo Group Research

Curated by ChEMBL
LigandPNGBDBM50000290(CHEMBL345269 | 2-(3,4-Dichloro-phenyl)-1-(4-hydrox...)
Affinity DataIC50: 1.40E+3nMAssay Description:Opioid receptor kappa agonist potency was determined in vitro using rabbit vas deferens(LVD) preparationMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetKappa-type opioid receptor(Human)
Glaxo Group Research

Curated by ChEMBL
LigandPNGBDBM50000294(CHEMBL148417 | 1-[2-(3,4-Dichloro-phenyl)-acetyl]-...)
Affinity DataIC50: 2.00E+3nMAssay Description:Kappa-opioid receptor agonist potency in vitro using rabbit vas deferens(LVD) preparationMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetKappa-type opioid receptor(Human)
Glaxo Group Research

Curated by ChEMBL
LigandPNGBDBM50000261(CHEMBL146474 | 2-(3,4-Dichloro-phenyl)-1-(2-hydrox...)
Affinity DataIC50: 2.20E+3nMAssay Description:Opioid receptor kappa agonist potency of the compound was determined in vitro using rabbit vas deferens(LVD) preparationMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetKappa-type opioid receptor(Human)
Glaxo Group Research

Curated by ChEMBL
LigandPNGBDBM50000291(CHEMBL356506 | 1-[2-(3,4-Dichloro-phenyl)-acetyl]-...)
Affinity DataIC50: 1.00E+4nMAssay Description:Kappa-opioid receptor agonist potency in vitro using rabbit vas deferens(LVD) preparationMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetKappa-type opioid receptor(Human)
Glaxo Group Research

Curated by ChEMBL
LigandPNGBDBM50000281(CHEMBL147437 | 2-(3,4-Dichloro-phenyl)-1-(2-methyl...)
Affinity DataIC50: 1.00E+4nMAssay Description:Opioid receptor kappa agonist potency was determined in vitro using rabbit vas deferens(LVD) preparationMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetKappa-type opioid receptor(Human)
Glaxo Group Research

Curated by ChEMBL
LigandPNGBDBM50000277(CHEMBL148416 | 1-(2-Allyl-2-pyrrolidin-1-ylmethyl-...)
Affinity DataIC50: 1.00E+4nMAssay Description:Opioid receptor kappa agonist potency was determined in vitro using rabbit vas deferens(LVD) preparationMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetKappa-type opioid receptor(Human)
Glaxo Group Research

Curated by ChEMBL
LigandPNGBDBM50000279(CHEMBL146533 | 1-[2-(3,4-Dichloro-phenyl)-acetyl]-...)
Affinity DataIC50: 1.00E+4nMAssay Description:Kappa-opioid receptor agonist potency in vitro using rabbit vas deferens(LVD) preparationMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetKappa-type opioid receptor(Human)
Glaxo Group Research

Curated by ChEMBL
LigandPNGBDBM50000266(CHEMBL148892 | 1-[2-(3,4-Dichloro-phenyl)-acetyl]-...)
Affinity DataIC50: 1.00E+4nMAssay Description:Kappa-opioid receptor agonist potency in vitro using rabbit vas deferens(LVD) preparationMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed