Compile Data Set for Download or QSAR
Report error Found 25 Enz. Inhib. hit(s) with all data for entry = 1053
TargetCyclin-A2/Cyclin-dependent kinase 2(Human)
Glaxosmithkline

LigandPNGBDBM8411(4-{[3-(4-nitrophenyl)-1H-pyrazol-5-yl]amino}benzen...)
Affinity DataIC50: 0.330nMpH: 7.5 T: 2°CAssay Description:The biochemical activity of compounds was determined by incubation with specific enzymes and substrates in the presence 1.4 uM ATP/[gamma-32P] ATP. A...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/29/2006
Entry Details Article
PubMed
TargetCyclin-A2/Cyclin-dependent kinase 2(Human)
Glaxosmithkline

LigandPNGBDBM8399(4-{[3-(4-aminophenyl)-1H-pyrazol-5-yl]amino}benzen...)
Affinity DataIC50: 0.340nMpH: 7.5 T: 2°CAssay Description:The biochemical activity of compounds was determined by incubation with specific enzymes and substrates in the presence 1.4 uM ATP/[gamma-32P] ATP. A...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/29/2006
Entry Details Article
PubMed
TargetCyclin-A2/Cyclin-dependent kinase 2(Human)
Glaxosmithkline

LigandPNGBDBM8401(4-{[3-(3-hydroxyphenyl)-1H-pyrazol-5-yl]amino}benz...)
Affinity DataIC50: 9.10nMpH: 7.5 T: 2°CAssay Description:The biochemical activity of compounds was determined by incubation with specific enzymes and substrates in the presence 1.4 uM ATP/[gamma-32P] ATP. A...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/29/2006
Entry Details Article
PubMed
TargetCyclin-A2/Cyclin-dependent kinase 2(Human)
Glaxosmithkline

LigandPNGBDBM8397(4-{[3-(4-bromophenyl)-1H-pyrazol-5-yl]amino}benzen...)
Affinity DataIC50: 10nMpH: 7.5 T: 2°CAssay Description:The biochemical activity of compounds was determined by incubation with specific enzymes and substrates in the presence 1.4 uM ATP/[gamma-32P] ATP. A...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/29/2006
Entry Details Article
PubMed
TargetCyclin-A2/Cyclin-dependent kinase 2(Human)
Glaxosmithkline

LigandPNGBDBM8404(4-{[3-(3-benzenesulfonamidophenyl)-1H-pyrazol-5-yl...)
Affinity DataIC50: 10.7nMpH: 7.5 T: 2°CAssay Description:The biochemical activity of compounds was determined by incubation with specific enzymes and substrates in the presence 1.4 uM ATP/[gamma-32P] ATP. A...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/29/2006
Entry Details Article
PubMed
TargetCyclin-A2/Cyclin-dependent kinase 2(Human)
Glaxosmithkline

LigandPNGBDBM8402(4-{[3-(3-methanesulfonamidophenyl)-1H-pyrazol-5-yl...)
Affinity DataIC50: 10.7nMpH: 7.5 T: 2°CAssay Description:The biochemical activity of compounds was determined by incubation with specific enzymes and substrates in the presence 1.4 uM ATP/[gamma-32P] ATP. A...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/29/2006
Entry Details Article
PubMed
TargetCyclin-A2/Cyclin-dependent kinase 2(Human)
Glaxosmithkline

LigandPNGBDBM8398(4-{[3-(3-fluoro-4-hydroxyphenyl)-1H-pyrazol-5-yl]a...)
Affinity DataIC50: 12.6nMpH: 7.5 T: 2°CAssay Description:The biochemical activity of compounds was determined by incubation with specific enzymes and substrates in the presence 1.4 uM ATP/[gamma-32P] ATP. A...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/29/2006
Entry Details Article
PubMed
TargetCyclin-A2/Cyclin-dependent kinase 2(Human)
Glaxosmithkline

LigandPNGBDBM8408(4-{[3-(4-fluorophenyl)-1H-pyrazol-5-yl]amino}benze...)
Affinity DataIC50: 17.4nMpH: 7.5 T: 2°CAssay Description:The biochemical activity of compounds was determined by incubation with specific enzymes and substrates in the presence 1.4 uM ATP/[gamma-32P] ATP. A...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/29/2006
Entry Details Article
PubMed
TargetCyclin-A2/Cyclin-dependent kinase 2(Human)
Glaxosmithkline

LigandPNGBDBM8405(4-{[3-(3-bromophenyl)-1H-pyrazol-5-yl]amino}benzen...)
Affinity DataIC50: 23.4nMpH: 7.5 T: 2°CAssay Description:The biochemical activity of compounds was determined by incubation with specific enzymes and substrates in the presence 1.4 uM ATP/[gamma-32P] ATP. A...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/29/2006
Entry Details Article
PubMed
TargetCyclin-A2/Cyclin-dependent kinase 2(Human)
Glaxosmithkline

LigandPNGBDBM8400(4-{[3-(3-methoxyphenyl)-1H-pyrazol-5-yl]amino}benz...)
Affinity DataIC50: 24.5nMpH: 7.5 T: 2°CAssay Description:The biochemical activity of compounds was determined by incubation with specific enzymes and substrates in the presence 1.4 uM ATP/[gamma-32P] ATP. A...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/29/2006
Entry Details Article
PubMed
TargetCyclin-A2/Cyclin-dependent kinase 2(Human)
Glaxosmithkline

LigandPNGBDBM8403(1-[2-fluoro-5-(trifluoromethyl)phenyl]-3-(3-{5-[(4...)
Affinity DataIC50: 61.6nMpH: 7.5 T: 2°CAssay Description:The biochemical activity of compounds was determined by incubation with specific enzymes and substrates in the presence 1.4 uM ATP/[gamma-32P] ATP. A...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/29/2006
Entry Details Article
PubMed
LigandPNGBDBM8397(4-{[3-(4-bromophenyl)-1H-pyrazol-5-yl]amino}benzen...)
Affinity DataIC50: 126nMpH: 7.5 T: 2°CAssay Description:The biochemical activity of compounds was determined by incubation with specific enzymes and substrates in the presence 1.4 uM ATP/[gamma-32P] ATP. A...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/29/2006
Entry Details Article
PubMed
TargetCyclin-A2/Cyclin-dependent kinase 2(Human)
Glaxosmithkline

LigandPNGBDBM8413(4-{[3-(3-aminophenyl)-1H-pyrazol-5-yl]amino}benzen...)
Affinity DataIC50: 166nMpH: 7.5 T: 2°CAssay Description:The biochemical activity of compounds was determined by incubation with specific enzymes and substrates in the presence 1.4 uM ATP/[gamma-32P] ATP. A...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/29/2006
Entry Details Article
PubMed
LigandPNGBDBM8398(4-{[3-(3-fluoro-4-hydroxyphenyl)-1H-pyrazol-5-yl]a...)
Affinity DataIC50: 200nMpH: 7.5 T: 2°CAssay Description:The biochemical activity of compounds was determined by incubation with specific enzymes and substrates in the presence 1.4 uM ATP/[gamma-32P] ATP. A...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/29/2006
Entry Details Article
PubMed
LigandPNGBDBM8400(4-{[3-(3-methoxyphenyl)-1H-pyrazol-5-yl]amino}benz...)
Affinity DataIC50: 398nMpH: 7.5 T: 2°CAssay Description:The biochemical activity of compounds was determined by incubation with specific enzymes and substrates in the presence 1.4 uM ATP/[gamma-32P] ATP. A...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/29/2006
Entry Details Article
PubMed
LigandPNGBDBM8401(4-{[3-(3-hydroxyphenyl)-1H-pyrazol-5-yl]amino}benz...)
Affinity DataIC50: 398nMpH: 7.5 T: 2°CAssay Description:The biochemical activity of compounds was determined by incubation with specific enzymes and substrates in the presence 1.4 uM ATP/[gamma-32P] ATP. A...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/29/2006
Entry Details Article
PubMed
TargetCyclin-A2/Cyclin-dependent kinase 2(Human)
Glaxosmithkline

LigandPNGBDBM8410(4-{[3-(3-fluoro-4-methoxyphenyl)-1H-pyrazol-5-yl]a...)
Affinity DataIC50: 407nMpH: 7.5 T: 2°CAssay Description:The biochemical activity of compounds was determined by incubation with specific enzymes and substrates in the presence 1.4 uM ATP/[gamma-32P] ATP. A...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/29/2006
Entry Details Article
PubMed
TargetCyclin-A2/Cyclin-dependent kinase 2(Human)
Glaxosmithkline

LigandPNGBDBM8412(4-({3-[3-(morpholin-4-yl)phenyl]-1H-pyrazol-5-yl}a...)
Affinity DataIC50: 490nMpH: 7.5 T: 2°CAssay Description:The biochemical activity of compounds was determined by incubation with specific enzymes and substrates in the presence 1.4 uM ATP/[gamma-32P] ATP. A...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/29/2006
Entry Details Article
PubMed
LigandPNGBDBM8399(4-{[3-(4-aminophenyl)-1H-pyrazol-5-yl]amino}benzen...)
Affinity DataIC50: 501nMpH: 7.5 T: 2°CAssay Description:The biochemical activity of compounds was determined by incubation with specific enzymes and substrates in the presence 1.4 uM ATP/[gamma-32P] ATP. A...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/29/2006
Entry Details Article
PubMed
LigandPNGBDBM8402(4-{[3-(3-methanesulfonamidophenyl)-1H-pyrazol-5-yl...)
Affinity DataIC50: 501nMpH: 7.5 T: 2°CAssay Description:The biochemical activity of compounds was determined by incubation with specific enzymes and substrates in the presence 1.4 uM ATP/[gamma-32P] ATP. A...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/29/2006
Entry Details Article
PubMed
LigandPNGBDBM8404(4-{[3-(3-benzenesulfonamidophenyl)-1H-pyrazol-5-yl...)
Affinity DataIC50: 501nMpH: 7.5 T: 2°CAssay Description:The biochemical activity of compounds was determined by incubation with specific enzymes and substrates in the presence 1.4 uM ATP/[gamma-32P] ATP. A...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/29/2006
Entry Details Article
PubMed
TargetCyclin-A2/Cyclin-dependent kinase 2(Human)
Glaxosmithkline

LigandPNGBDBM8406(N-(4-{[3-(3-bromophenyl)-1H-pyrazol-5-yl]amino}phe...)
Affinity DataIC50: 602nMpH: 7.5 T: 2°CAssay Description:The biochemical activity of compounds was determined by incubation with specific enzymes and substrates in the presence 1.4 uM ATP/[gamma-32P] ATP. A...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/29/2006
Entry Details Article
PubMed
LigandPNGBDBM8403(1-[2-fluoro-5-(trifluoromethyl)phenyl]-3-(3-{5-[(4...)
Affinity DataIC50: 794nMpH: 7.5 T: 2°CAssay Description:The biochemical activity of compounds was determined by incubation with specific enzymes and substrates in the presence 1.4 uM ATP/[gamma-32P] ATP. A...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/29/2006
Entry Details Article
PubMed
TargetCyclin-A2/Cyclin-dependent kinase 2(Human)
Glaxosmithkline

LigandPNGBDBM8407(3-{[3-(4-fluorophenyl)-1H-pyrazol-5-yl]amino}benze...)
Affinity DataIC50: 871nMpH: 7.5 T: 2°CAssay Description:The biochemical activity of compounds was determined by incubation with specific enzymes and substrates in the presence 1.4 uM ATP/[gamma-32P] ATP. A...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/29/2006
Entry Details Article
PubMed
TargetCyclin-A2/Cyclin-dependent kinase 2(Human)
Glaxosmithkline

LigandPNGBDBM8409(4-({3-[4-(dimethylamino)phenyl]-1H-pyrazol-5-yl}am...)
Affinity DataIC50: 2.00E+3nMpH: 7.5 T: 2°CAssay Description:The biochemical activity of compounds was determined by incubation with specific enzymes and substrates in the presence 1.4 uM ATP/[gamma-32P] ATP. A...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/29/2006
Entry Details Article
PubMed