Compile Data Set for Download or QSAR
Report error Found 30 Enz. Inhib. hit(s) with all data for entry = 50037177
TargetProthrombin(Human)
Lg Life Sciences

Curated by ChEMBL
LigandPNGBDBM50111101(1-(2-Methanesulfonylamino-3,3-diphenyl-propionyl)-...)
Affinity DataKi:  0.00300nMAssay Description:In vitro inhibition constant (Ki) against human thrombinMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/29/2012
Entry Details Article
PubMed
TargetProthrombin(Human)
Lg Life Sciences

Curated by ChEMBL
LigandPNGBDBM50111110(CHEMBL331771 | 2N-(4-Benzamidinemethyl)-1-[2-amino...)
Affinity DataKi:  0.00300nMAssay Description:In vitro inhibition constant (Ki) against human thrombinMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/29/2012
Entry Details Article
PubMed
TargetProthrombin(Human)
Lg Life Sciences

Curated by ChEMBL
LigandPNGBDBM50131789(1-(2-sulfonamide-amino-3,3-diphenyl-propionyl)-pyr...)
Affinity DataKi:  0.00400nMAssay Description:In vitro inhibition constant (Ki) against human thrombinMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/29/2012
Entry Details Article
PubMed
TargetProthrombin(Human)
Lg Life Sciences

Curated by ChEMBL
LigandPNGBDBM50111105(CHEMBL1795037 | CHEMBL7895 | (S)-1-((R)-2-Methanes...)
Affinity DataKi:  0.00500nMAssay Description:In vitro inhibition constant (Ki) against human thrombinMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/29/2012
Entry Details Article
PubMed
TargetProthrombin(Human)
Lg Life Sciences

Curated by ChEMBL
LigandPNGBDBM50131790(1-(2-sulfonamideamino-3,3-diphenyl-propionyl)-pyrr...)
Affinity DataKi:  0.00800nMAssay Description:In vitro inhibition constant (Ki) against human thrombinMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/29/2012
Entry Details Article
PubMed
TargetProthrombin(Human)
Lg Life Sciences

Curated by ChEMBL
LigandPNGBDBM50131778(3-(1-Benzhydryl-2-{2-[(5-carbamimidoyl-thiophen-2-...)
Affinity DataKi:  0.0100nMAssay Description:In vitro inhibition constant (Ki) against human thrombinMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/29/2012
Entry Details Article
PubMed
TargetProthrombin(Human)
Lg Life Sciences

Curated by ChEMBL
LigandPNGBDBM50131795(1-(2-sulfonamideamino-3,3-diphenyl-propionyl)-pyrr...)
Affinity DataKi:  0.0100nMAssay Description:In vitro inhibition constant (Ki) against human thrombinMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/29/2012
Entry Details Article
PubMed
TargetProthrombin(Human)
Lg Life Sciences

Curated by ChEMBL
LigandPNGBDBM50111120(CHEMBL330949 | 2N-(4-Benzamidinemethyl)-1-[2-Amino...)
Affinity DataKi:  0.0130nMAssay Description:In vitro inhibition constant (Ki) against human thrombinMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/29/2012
Entry Details Article
PubMed
TargetProthrombin(Human)
Lg Life Sciences

Curated by ChEMBL
LigandPNGBDBM50131796((1-Benzhydryl-2-{2-[(5-carbamimidoyl-thiophen-2-yl...)
Affinity DataKi:  0.0150nMAssay Description:In vitro inhibition constant (Ki) against human thrombinMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/29/2012
Entry Details Article
PubMed
TargetProthrombin(Human)
Lg Life Sciences

Curated by ChEMBL
LigandPNGBDBM50131791(1-(2-sulfonamideamino-3,3-diphenyl-propionyl)-pyrr...)
Affinity DataKi:  0.0150nMAssay Description:In vitro inhibition constant (Ki) against human thrombinMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/29/2012
Entry Details Article
PubMed
TargetProthrombin(Human)
Lg Life Sciences

Curated by ChEMBL
LigandPNGBDBM50131780((1-Benzhydryl-2-{2-[(5-carbamimidoyl-thiophen-2-yl...)
Affinity DataKi:  0.0150nMAssay Description:In vitro inhibition constant (Ki) against human thrombinMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/29/2012
Entry Details Article
PubMed
TargetProthrombin(Human)
Lg Life Sciences

Curated by ChEMBL
LigandPNGBDBM50131792((1-Benzhydryl-2-{2-[(6-carbamimidoyl-pyridin-3-ylm...)
Affinity DataKi:  0.0170nMAssay Description:In vitro inhibition constant (Ki) against human thrombinMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/29/2012
Entry Details Article
PubMed
TargetProthrombin(Human)
Lg Life Sciences

Curated by ChEMBL
LigandPNGBDBM50131798(1-(2-Methylamino-3,3-diphenyl-propionyl)-pyrrolidi...)
Affinity DataKi:  0.0200nMAssay Description:In vitro inhibition constant (Ki) against human thrombinMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/29/2012
Entry Details Article
PubMed
TargetProthrombin(Human)
Lg Life Sciences

Curated by ChEMBL
LigandPNGBDBM50131782(1-(2-sulfonamide-amino-3,3-diphenyl-propionyl)-pyr...)
Affinity DataKi:  0.0200nMAssay Description:In vitro inhibition constant (Ki) against human thrombinMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/29/2012
Entry Details Article
PubMed
TargetProthrombin(Human)
Lg Life Sciences

Curated by ChEMBL
LigandPNGBDBM50111122(CHEMBL120187 | 2N-(4-Benzamidinemethyl)-1-[2-Carba...)
Affinity DataKi:  0.0300nMAssay Description:In vitro inhibition constant (Ki) against human thrombinMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/29/2012
Entry Details Article
PubMed
TargetProthrombin(Human)
Lg Life Sciences

Curated by ChEMBL
LigandPNGBDBM50131787((1-Benzhydryl-2-{2-[(5-carbamimidoyl-thiophen-3-yl...)
Affinity DataKi:  0.100nMAssay Description:In vitro inhibition constant (Ki) against human thrombinMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/29/2012
Entry Details Article
PubMed
TargetProthrombin(Human)
Lg Life Sciences

Curated by ChEMBL
LigandPNGBDBM50131781(1-(2-sulfonamide-amino-3,3-diphenyl-propionyl)-pyr...)
Affinity DataKi:  0.120nMAssay Description:In vitro inhibition constant (Ki) against human thrombinMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/29/2012
Entry Details Article
PubMed
TargetProthrombin(Human)
Lg Life Sciences

Curated by ChEMBL
LigandPNGBDBM50131797(1-(2-sulfonamide-amino-3,3-diphenyl-propionyl)-pyr...)
Affinity DataKi:  0.160nMAssay Description:In vitro inhibition constant (Ki) against human thrombinMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/29/2012
Entry Details Article
PubMed
TargetProthrombin(Human)
Lg Life Sciences

Curated by ChEMBL
LigandPNGBDBM50131779((1-Benzhydryl-2-{2-[(4-carbamimidoyl-thiophen-2-yl...)
Affinity DataKi:  0.170nMAssay Description:In vitro inhibition constant (Ki) against human thrombinMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/29/2012
Entry Details Article
PubMed
TargetSerine protease 1/Trypsin-2(Human)
Lg Life Sciences

Curated by ChEMBL
LigandPNGBDBM50131780((1-Benzhydryl-2-{2-[(5-carbamimidoyl-thiophen-2-yl...)
Affinity DataKi:  0.300nMAssay Description:In vitro inhibition constant (Ki) against human trypsin was determinedMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/29/2012
Entry Details Article
PubMed
TargetProthrombin(Human)
Lg Life Sciences

Curated by ChEMBL
LigandPNGBDBM50131784(2-{4-[(Z)-amino(hydrazono)methyl]phenyl}-N-cyclope...)
Affinity DataKi:  0.400nMAssay Description:In vitro inhibition constant (Ki) against human thrombinMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/29/2012
Entry Details Article
PubMed
TargetProthrombin(Human)
Lg Life Sciences

Curated by ChEMBL
LigandPNGBDBM50131783(1-(2-sulfonamide-amino-3,3-diphenyl-propionyl)-pyr...)
Affinity DataKi:  0.430nMAssay Description:In vitro inhibition constant (Ki) against human thrombinMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/29/2012
Entry Details Article
PubMed
TargetProthrombin(Human)
Lg Life Sciences

Curated by ChEMBL
LigandPNGBDBM50131788((1-Benzhydryl-2-{2-[(5-carbamimidoyl-thiophen-3-yl...)
Affinity DataKi:  0.600nMAssay Description:In vitro inhibition constant (Ki) against human thrombinMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/29/2012
Entry Details Article
PubMed
TargetProthrombin(Human)
Lg Life Sciences

Curated by ChEMBL
LigandPNGBDBM50131793((1-Benzhydryl-2-{2-[(4-carbamimidoyl-thiazol-2-ylm...)
Affinity DataKi:  0.640nMAssay Description:In vitro inhibition constant (Ki) against human thrombinMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/29/2012
Entry Details Article
PubMed
TargetProthrombin(Human)
Lg Life Sciences

Curated by ChEMBL
LigandPNGBDBM50131777((1-Benzhydryl-2-{2-[(5-carbamimidoyl-furan-3-ylmet...)
Affinity DataKi:  1.40nMAssay Description:In vitro inhibition constant (Ki) against human thrombinMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/29/2012
Entry Details Article
PubMed
TargetSerine protease 1(Bovine)
Lg Life Sciences

Curated by ChEMBL
LigandPNGBDBM50131780((1-Benzhydryl-2-{2-[(5-carbamimidoyl-thiophen-2-yl...)
Affinity DataKi:  3nMAssay Description:In vitro inhibition constant (Ki) against human bovine trypsin was determinedMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/29/2012
Entry Details Article
PubMed
TargetProthrombin(Human)
Lg Life Sciences

Curated by ChEMBL
LigandPNGBDBM50038001(CHEMBL1166 | (2R,4S)-1-[5-Guanidino-2-(3-methyl-1,...)
Affinity DataKi:  4nMAssay Description:In vitro inhibition constant (Ki) against human thrombinMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/29/2012
Entry Details Article
PubMed
TargetCoagulation factor X(Human)
Lg Life Sciences

Curated by ChEMBL
LigandPNGBDBM50131780((1-Benzhydryl-2-{2-[(5-carbamimidoyl-thiophen-2-yl...)
Affinity DataKi:  22.5nMAssay Description:In vitro inhibition constant (Ki) against human Coagulation factor X was determinedMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/29/2012
Entry Details Article
PubMed
TargetTissue-type plasminogen activator(Human)
Lg Life Sciences

Curated by ChEMBL
LigandPNGBDBM50131780((1-Benzhydryl-2-{2-[(5-carbamimidoyl-thiophen-2-yl...)
Affinity DataKi:  433nMAssay Description:In vitro inhibition constant (Ki) against human Tissue type plasminogen activator was determinedMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/29/2012
Entry Details Article
PubMed
TargetPlasminogen(Human)
Lg Life Sciences

Curated by ChEMBL
LigandPNGBDBM50131780((1-Benzhydryl-2-{2-[(5-carbamimidoyl-thiophen-2-yl...)
Affinity DataKi:  7.40E+3nMAssay Description:In vitro inhibition constant (Ki) against human plasmin was determinedMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/29/2012
Entry Details Article
PubMed