Compile Data Set for Download or QSAR
Report error Found 30 Enz. Inhib. hit(s) with all data for entry = 50013487
TargetC-X-C chemokine receptor type 2(Human)
Astrazeneca R&D Charnwood

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50221044BDBM50221044(CHEMBL309253)
Affinity DataIC50: 28nMAssay Description:Inhibition of binding of [125I]IL8 to human recombinant CXC chemokine receptor 2 (CXCR2) expressed in HEK 293 membranesMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetC-X-C chemokine receptor type 2(Human)
Astrazeneca R&D Charnwood

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50131181BDBM50131181(2-(3-Chloro-benzyl)-5-(2,4-dichloro-phenyl)-2H-[1,...)
Affinity DataIC50: 92nMAssay Description:Inhibition of binding of [125I]IL8 to human recombinant CXC chemokine receptor 2 (CXCR2) expressed in HEK 293 membranesMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetC-X-C chemokine receptor type 2(Human)
Astrazeneca R&D Charnwood

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50131188BDBM50131188(5-(2,4-Dichloro-phenyl)-2-(3-phenoxy-benzyl)-2H-[1...)
Affinity DataIC50: 170nMAssay Description:Inhibition of binding of [125I]IL8 to human recombinant CXC chemokine receptor 2 (CXCR2) expressed in HEK 293 membranesMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetC-X-C chemokine receptor type 2(Human)
Astrazeneca R&D Charnwood

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50131204BDBM50131204(2-(4-Chloro-benzyl)-5-(2,4-dichloro-phenyl)-2H-[1,...)
Affinity DataIC50: 300nMAssay Description:Inhibition of binding of [125I]IL8 to human recombinant CXC chemokine receptor 2 (CXCR2) expressed in HEK 293 membranesMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetC-X-C chemokine receptor type 2(Human)
Astrazeneca R&D Charnwood

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50131199BDBM50131199(2-Benzyl-5-(2,3-dichloro-phenyl)-2H-[1,2,4]triazol...)
Affinity DataIC50: 350nMAssay Description:Inhibition of binding of [125I]IL8 to human recombinant CXC chemokine receptor 2 (CXCR2) expressed in HEK 293 membranesMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetC-X-C chemokine receptor type 2(Human)
Astrazeneca R&D Charnwood

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50131192BDBM50131192(2-Benzyl-5-(2-bromo-phenyl)-2H-[1,2,4]triazole-3-t...)
Affinity DataIC50: 350nMAssay Description:Inhibition of binding of [125I]IL8 to human recombinant CXC chemokine receptor 2 (CXCR2) expressed in HEK 293 membranesMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetC-X-C chemokine receptor type 2(Human)
Astrazeneca R&D Charnwood

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50131193BDBM50131193(2-Benzyl-5-(2,4-dichloro-phenyl)-2H-[1,2,4]triazol...)
Affinity DataIC50: 410nMAssay Description:Inhibition of binding of [125I]IL8 to human recombinant CXC chemokine receptor 2 (CXCR2) expressed in HEK 293 membranesMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetC-X-C chemokine receptor type 2(Human)
Astrazeneca R&D Charnwood

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50131197BDBM50131197(5-(2,4-Dichloro-phenyl)-2-phenethyl-2H-[1,2,4]tria...)
Affinity DataIC50: 450nMAssay Description:Inhibition of binding of [125I]IL8 to human recombinant CXC chemokine receptor 2 (CXCR2) expressed in HEK 293 membranesMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetC-X-C chemokine receptor type 2(Human)
Astrazeneca R&D Charnwood

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50131209BDBM50131209(2-Benzyl-5-(2-chloro-phenyl)-2H-[1,2,4]triazole-3-...)
Affinity DataIC50: 450nMAssay Description:Inhibition of binding of [125I]IL8 to human recombinant CXC chemokine receptor 2 (CXCR2) expressed in HEK 293 membranesMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetC-X-C chemokine receptor type 2(Human)
Astrazeneca R&D Charnwood

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50131189BDBM50131189(2-Benzyl-5-(2,5-dichloro-phenyl)-2H-[1,2,4]triazol...)
Affinity DataIC50: 670nMAssay Description:Inhibition of binding of [125I]IL8 to human recombinant CXC chemokine receptor 2 (CXCR2) expressed in HEK 293 membranesMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetC-X-C chemokine receptor type 2(Human)
Astrazeneca R&D Charnwood

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50131194BDBM50131194(5-(2,4-Dichloro-phenyl)-2-(3-methyl-benzyl)-2H-[1,...)
Affinity DataIC50: 730nMAssay Description:Inhibition of binding of [125I]IL8 to human recombinant CXC chemokine receptor 2 (CXCR2) expressed in HEK 293 membranesMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetC-X-C chemokine receptor type 2(Human)
Astrazeneca R&D Charnwood

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50131190BDBM50131190(2-Benzyl-5-(3,4-dichloro-phenyl)-2H-[1,2,4]triazol...)
Affinity DataIC50: 800nMAssay Description:Inhibition of binding of [125I]IL8 to human recombinant CXC chemokine receptor 2 (CXCR2) expressed in HEK 293 membranesMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetC-X-C chemokine receptor type 2(Human)
Astrazeneca R&D Charnwood

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50131200BDBM50131200(2-Benzyl-5-(4-chloro-phenyl)-2H-[1,2,4]triazole-3-...)
Affinity DataIC50: 830nMAssay Description:Inhibition of binding of [125I]IL8 to human recombinant CXC chemokine receptor 2 (CXCR2) expressed in HEK 293 membranesMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetC-X-C chemokine receptor type 2(Human)
Astrazeneca R&D Charnwood

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50131186BDBM50131186(2-Benzyl-5-(2-fluoro-phenyl)-2H-[1,2,4]triazole-3-...)
Affinity DataIC50: 890nMAssay Description:Inhibition of binding of [125I]IL8 to human recombinant CXC chemokine receptor 2 (CXCR2) expressed in HEK 293 membranesMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetC-X-C chemokine receptor type 2(Human)
Astrazeneca R&D Charnwood

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50131182BDBM50131182(2-Benzyl-5-(3-chloro-phenyl)-2H-[1,2,4]triazole-3-...)
Affinity DataIC50: 1.00E+3nMAssay Description:Inhibition of binding of [125I]IL8 to human recombinant CXC chemokine receptor 2 (CXCR2) expressed in HEK 293 membranesMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetC-X-C chemokine receptor type 2(Human)
Astrazeneca R&D Charnwood

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50131187BDBM50131187(2-Benzyl-5-o-tolyl-2H-[1,2,4]triazole-3-thiol | CH...)
Affinity DataIC50: 1.40E+3nMAssay Description:Inhibition of binding of [125I]IL8 to human recombinant CXC chemokine receptor 2 (CXCR2) expressed in HEK 293 membranesMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetC-X-C chemokine receptor type 2(Human)
Astrazeneca R&D Charnwood

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50131201BDBM50131201(2-Benzyl-5-(2-methoxy-phenyl)-2H-[1,2,4]triazole-3...)
Affinity DataIC50: 1.40E+3nMAssay Description:Inhibition of binding of [125I]IL8 to human recombinant CXC chemokine receptor 2 (CXCR2) expressed in HEK 293 membranesMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetC-X-C chemokine receptor type 2(Human)
Astrazeneca R&D Charnwood

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50131206BDBM50131206(2-Benzyl-5-thiophen-2-yl-2H-[1,2,4]triazole-3-thio...)
Affinity DataIC50: 2.00E+3nMAssay Description:Inhibition of binding of [125I]IL8 to human recombinant CXC chemokine receptor 2 (CXCR2) expressed in HEK 293 membranesMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetC-X-C chemokine receptor type 2(Human)
Astrazeneca R&D Charnwood

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50131185BDBM50131185(2-Benzyl-5-(3,5-dichloro-phenyl)-2H-[1,2,4]triazol...)
Affinity DataIC50: 2.00E+3nMAssay Description:Inhibition of binding of [125I]IL8 to human recombinant CXC chemokine receptor 2 (CXCR2) expressed in HEK 293 membranesMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetC-X-C chemokine receptor type 2(Human)
Astrazeneca R&D Charnwood

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50131198BDBM50131198(2-Benzyl-5-(4-methoxy-phenyl)-2H-[1,2,4]triazole-3...)
Affinity DataIC50: 2.30E+3nMAssay Description:Inhibition of binding of [125I]IL8 to human recombinant CXC chemokine receptor 2 (CXCR2) expressed in HEK 293 membranesMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetC-X-C chemokine receptor type 2(Human)
Astrazeneca R&D Charnwood

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50131203BDBM50131203(2-Benzyl-5-phenyl-2H-[1,2,4]triazole-3-thiol | CHE...)
Affinity DataIC50: 2.40E+3nMAssay Description:Inhibition of binding of [125I]IL8 to human recombinant CXC chemokine receptor 2 (CXCR2) expressed in HEK 293 membranesMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetC-X-C chemokine receptor type 2(Human)
Astrazeneca R&D Charnwood

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50131207BDBM50131207(2-Benzyl-5-(4-trifluoromethyl-phenyl)-2H-[1,2,4]tr...)
Affinity DataIC50: 2.80E+3nMAssay Description:Inhibition of binding of [125I]IL8 to human recombinant CXC chemokine receptor 2 (CXCR2) expressed in HEK 293 membranesMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetC-X-C chemokine receptor type 2(Human)
Astrazeneca R&D Charnwood

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50131183BDBM50131183(2-Benzyl-5-(3-trifluoromethyl-phenyl)-2H-[1,2,4]tr...)
Affinity DataIC50: 3.50E+3nMAssay Description:Inhibition of binding of [125I]IL8 to human recombinant CXC chemokine receptor 2 (CXCR2) expressed in HEK 293 membranesMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetC-X-C chemokine receptor type 2(Human)
Astrazeneca R&D Charnwood

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50131195BDBM50131195(4-(1-Benzyl-5-mercapto-1H-[1,2,4]triazol-3-yl)-ben...)
Affinity DataIC50: 3.50E+3nMAssay Description:Inhibition of binding of [125I]IL8 to human recombinant CXC chemokine receptor 2 (CXCR2) expressed in HEK 293 membranesMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetC-X-C chemokine receptor type 2(Human)
Astrazeneca R&D Charnwood

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50131208BDBM50131208(2-Benzyl-5-furan-2-yl-2H-[1,2,4]triazole-3-thiol |...)
Affinity DataIC50: 4.20E+3nMAssay Description:Inhibition of binding of [125I]IL8 to human recombinant CXC chemokine receptor 2 (CXCR2) expressed in HEK 293 membranesMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetC-X-C chemokine receptor type 2(Human)
Astrazeneca R&D Charnwood

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50131202BDBM50131202(5-(2,4-Dichloro-phenyl)-2-(3-methoxy-benzyl)-2H-[1...)
Affinity DataIC50: 4.20E+3nMAssay Description:Inhibition of binding of [125I]IL8 to human recombinant CXC chemokine receptor 2 (CXCR2) expressed in HEK 293 membranesMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetC-X-C chemokine receptor type 2(Human)
Astrazeneca R&D Charnwood

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50131205BDBM50131205(3-(5-Mercapto-3-phenyl-[1,2,4]triazol-1-ylmethyl)-...)
Affinity DataIC50: 4.40E+3nMAssay Description:Inhibition of binding of [125I]IL8 to human recombinant CXC chemokine receptor 2 (CXCR2) expressed in HEK 293 membranesMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetC-X-C chemokine receptor type 2(Human)
Astrazeneca R&D Charnwood

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50221043BDBM50221043(CHEMBL315771)
Affinity DataIC50: 4.60E+3nMAssay Description:Inhibition of binding of [125I]IL8 to human recombinant CXC chemokine receptor 2 (CXCR2) expressed in HEK 293 membranesMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetC-X-C chemokine receptor type 2(Human)
Astrazeneca R&D Charnwood

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50131196BDBM50131196(2-Benzyl-5-pyridin-4-yl-2H-[1,2,4]triazole-3-thiol...)
Affinity DataIC50: 7.70E+3nMAssay Description:Inhibition of binding of [125I]IL8 to human recombinant CXC chemokine receptor 2 (CXCR2) expressed in HEK 293 membranesMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetC-X-C chemokine receptor type 2(Human)
Astrazeneca R&D Charnwood

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50131180BDBM50131180(5-(2,4-Dichloro-phenyl)-2-(4-methoxy-benzyl)-2H-[1...)
Affinity DataIC50: 1.00E+4nMAssay Description:Inhibition of binding of [125I]IL8 to human recombinant CXC chemokine receptor 2 (CXCR2) expressed in HEK 293 membranesMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed