Compile Data Set for Download or QSAR
Report error Found 11 Enz. Inhib. hit(s) with all data for entry = 1207
TargetAromatase(Human)
University of Bath

LigandPNGBDBM10016(4-{[(4-bromophenyl)methyl](4H-1,2,4-triazol-4-yl)a...)
Affinity DataIC50: 0.5nMpH: 7.5 T: 2°CAssay Description:The extent of in vitro inhibition of aromatase activities was assessed using intact monolayers of JEG-3 cells. Aromatase activity was measured using ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/19/2006
Entry Details Article
PubMed
TargetAromatase(Human)
University of Bath

LigandPNGBDBM10020(YM511-based dual aromatase-sulfatase inhibitor (DA...)
Affinity DataIC50: 0.820nMpH: 7.5 T: 2°CAssay Description:The extent of in vitro inhibition of aromatase activities was assessed using intact monolayers of JEG-3 cells. Aromatase activity was measured using ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/19/2006
Entry Details Article
PubMed
TargetAromatase(Human)
University of Bath

LigandPNGBDBM10019((2-chloro-4-{[(4-cyanophenyl)(4H-1,2,4-triazol-4-y...)
Affinity DataIC50: 2.30nMpH: 7.5 T: 2°CAssay Description:The extent of in vitro inhibition of aromatase activities was assessed using intact monolayers of JEG-3 cells. Aromatase activity was measured using ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/19/2006
Entry Details Article
PubMed
TargetAromatase(Human)
University of Bath

LigandPNGBDBM10018(YM511-based dual aromatase-sulfatase inhibitor (DA...)
Affinity DataIC50: 12nMpH: 7.5 T: 2°CAssay Description:The extent of in vitro inhibition of aromatase activities was assessed using intact monolayers of JEG-3 cells. Aromatase activity was measured using ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/19/2006
Entry Details Article
PubMed
TargetSteryl-sulfatase(Human)
University of Bath

LigandPNGBDBM10019((2-chloro-4-{[(4-cyanophenyl)(4H-1,2,4-triazol-4-y...)
Affinity DataIC50: 20nMpH: 7.5 T: 2°CAssay Description:The extent of in vitro inhibition of sulfatase activities was assessed using intact monolayers of JEG-3 cells. Sulfatase activity was measured using ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/19/2006
Entry Details Article
PubMed
TargetAromatase(Human)
University of Bath

LigandPNGBDBM10021(YM511-based dual aromatase-sulfatase inhibitor (DA...)
Affinity DataIC50: 39nMpH: 7.5 T: 2°CAssay Description:The extent of in vitro inhibition of aromatase activities was assessed using intact monolayers of JEG-3 cells. Aromatase activity was measured using ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/19/2006
Entry Details Article
PubMed
TargetSteryl-sulfatase(Human)
University of Bath

LigandPNGBDBM10020(YM511-based dual aromatase-sulfatase inhibitor (DA...)
Affinity DataIC50: 39nMpH: 7.5 T: 2°CAssay Description:The extent of in vitro inhibition of sulfatase activities was assessed using intact monolayers of JEG-3 cells. Sulfatase activity was measured using ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/19/2006
Entry Details Article
PubMed
TargetSteryl-sulfatase(Human)
University of Bath

LigandPNGBDBM10018(YM511-based dual aromatase-sulfatase inhibitor (DA...)
Affinity DataIC50: 40nMpH: 7.5 T: 2°CAssay Description:The extent of in vitro inhibition of sulfatase activities was assessed using intact monolayers of JEG-3 cells. Sulfatase activity was measured using ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/19/2006
Entry Details Article
PubMed
TargetAromatase(Human)
University of Bath

LigandPNGBDBM10017(YM511 Analog 4 | (4-{[(4-cyanophenyl)(4H-1,2,4-tri...)
Affinity DataIC50: 100nMpH: 7.5 T: 2°CAssay Description:The extent of in vitro inhibition of aromatase activities was assessed using intact monolayers of JEG-3 cells. Aromatase activity was measured using ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/19/2006
Entry Details Article
PubMed
TargetSteryl-sulfatase(Human)
University of Bath

LigandPNGBDBM10017(YM511 Analog 4 | (4-{[(4-cyanophenyl)(4H-1,2,4-tri...)
Affinity DataIC50: 227nMpH: 7.5 T: 2°CAssay Description:The extent of in vitro inhibition of sulfatase activities was assessed using intact monolayers of JEG-3 cells. Sulfatase activity was measured using ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/19/2006
Entry Details Article
PubMed
TargetSteryl-sulfatase(Human)
University of Bath

LigandPNGBDBM10021(YM511-based dual aromatase-sulfatase inhibitor (DA...)
Affinity DataIC50: 5.13E+3nMpH: 7.5 T: 2°CAssay Description:The extent of in vitro inhibition of sulfatase activities was assessed using intact monolayers of JEG-3 cells. Sulfatase activity was measured using ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/19/2006
Entry Details Article
PubMed