Compile Data Set for Download or QSAR
Report error Found 54 Enz. Inhib. hit(s) with all data for entry = 2439
TargetEstrogen receptor beta(Human)
Novartis Pharmaceuticals

LigandPNGBDBM20607((2-{4-[(1Z)-1,2-diphenylbut-1-en-1-yl]phenoxy}ethy...)
Affinity DataEC50: >1.00E+3nMT: 2°CAssay Description:Radioligand binding assay was performed by using 96-well microtiterplates containing ER, 17beta-estradiol, and the test compound to be tested and SPA...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/16/2008
Entry Details Article
PubMed
TargetEstrogen receptor(Human)
Novartis Pharmaceuticals

LigandPNGBDBM20607((2-{4-[(1Z)-1,2-diphenylbut-1-en-1-yl]phenoxy}ethy...)
Affinity DataEC50:  622nMpH: 7.4 T: 2°CAssay Description:Radioligand binding assay was performed by using 96-well microtiterplates containing ER, 17beta-estradiol, and the test compound to be tested and SPA...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/16/2008
Entry Details Article
PubMed
TargetEstrogen receptor(Human)
Novartis Pharmaceuticals

LigandPNGBDBM20606((5R,6S)-6-phenyl-5-[4-(2-pyrrolidin-1-ylethoxy)phe...)
Affinity DataIC50: 4nM EC50:  3.10nMpH: 7.4 T: 2°CAssay Description:Radioligand binding assay was performed by using 96-well microtiterplates containing ER, 17beta-estradiol, and the test compound to be tested and SPA...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/16/2008
Entry Details Article
PubMed
TargetEstrogen receptor beta(Human)
Novartis Pharmaceuticals

LigandPNGBDBM20606((5R,6S)-6-phenyl-5-[4-(2-pyrrolidin-1-ylethoxy)phe...)
Affinity DataIC50: 13nM EC50:  24nMT: 2°CAssay Description:Radioligand binding assay was performed by using 96-well microtiterplates containing ER, 17beta-estradiol, and the test compound to be tested and SPA...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/16/2008
Entry Details Article
PubMed
TargetEstrogen receptor(Human)
Novartis Pharmaceuticals

LigandPNGBDBM20608([3H]4-OHT | cid_449459 | CHEMBL489 | AFIMOXIFENE |...)
Affinity DataIC50: 17nM EC50:  10.3nMpH: 7.4 T: 2°CAssay Description:Radioligand binding assay was performed by using 96-well microtiterplates containing ER, 17beta-estradiol, and the test compound to be tested and SPA...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/16/2008
Entry Details Article
PubMedPDB3D3D Structure (crystal)
TargetEstrogen receptor(Human)
Novartis Pharmaceuticals

LigandPNGBDBM20586(2-phenyl-1-{4-[2-(piperidin-1-yl)ethoxy]phenyl}-1,...)
Affinity DataIC50: 19nM EC50:  16.5nMpH: 7.4 T: 2°CAssay Description:Radioligand binding assay was performed by using 96-well microtiterplates containing ER, 17beta-estradiol, and the test compound to be tested and SPA...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/16/2008
Entry Details Article
PubMedPDB3D3D Structure (crystal)
TargetEstrogen receptor(Human)
Novartis Pharmaceuticals

LigandPNGBDBM20585(2-phenyl-1-{4-[2-(pyrrolidin-1-yl)ethoxy]phenyl}-1...)
Affinity DataIC50: 21nM EC50:  10.7nMpH: 7.4 T: 2°CAssay Description:Radioligand binding assay was performed by using 96-well microtiterplates containing ER, 17beta-estradiol, and the test compound to be tested and SPA...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/16/2008
Entry Details Article
PubMed
TargetEstrogen receptor beta(Human)
Novartis Pharmaceuticals

LigandPNGBDBM20608([3H]4-OHT | cid_449459 | CHEMBL489 | AFIMOXIFENE |...)
Affinity DataIC50: 21nM EC50:  32nMT: 2°CAssay Description:Radioligand binding assay was performed by using 96-well microtiterplates containing ER, 17beta-estradiol, and the test compound to be tested and SPA...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/16/2008
Entry Details Article
PubMedPDB3D3D Structure (crystal)
TargetEstrogen receptor(Human)
Novartis Pharmaceuticals

LigandPNGBDBM19441(Evista | CHEMBL81 | Keoxifene | Raloxifene, 6 | RA...)
Affinity DataIC50: 22nM EC50:  2.40nMpH: 7.4 T: 2°CAssay Description:Radioligand binding assay was performed by using 96-well microtiterplates containing ER, 17beta-estradiol, and the test compound to be tested and SPA...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/16/2008
Entry Details Article
PubMed
TargetEstrogen receptor beta(Human)
Novartis Pharmaceuticals

LigandPNGBDBM17292([2,4,6,7-3H]-17beta-estradiol | [3H]-estradiol | 1...)
Affinity DataIC50: 24nMT: 2°CAssay Description:Radioligand binding assay was performed by using 96-well microtiterplates containing ER, 17beta-estradiol, and the test compound to be tested and SPA...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/16/2008
Entry Details Article
PubMed
TargetEstrogen receptor(Human)
Novartis Pharmaceuticals

LigandPNGBDBM20594(2-(4-chlorophenyl)-1-methyl-1-{4-[2-(pyrrolidin-1-...)
Affinity DataIC50: 27nM EC50:  3.30nMpH: 7.4 T: 2°CAssay Description:Radioligand binding assay was performed by using 96-well microtiterplates containing ER, 17beta-estradiol, and the test compound to be tested and SPA...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/16/2008
Entry Details Article
PubMed
TargetEstrogen receptor(Human)
Novartis Pharmaceuticals

LigandPNGBDBM17292([2,4,6,7-3H]-17beta-estradiol | [3H]-estradiol | 1...)
Affinity DataIC50: 28nMpH: 7.4 T: 2°CAssay Description:Radioligand binding assay was performed by using 96-well microtiterplates containing ER, 17beta-estradiol, and the test compound to be tested and SPA...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/16/2008
Entry Details Article
PubMed
TargetEstrogen receptor(Human)
Novartis Pharmaceuticals

LigandPNGBDBM20591(1-methyl-2-(4-methylphenyl)-1-{4-[2-(piperidin-1-y...)
Affinity DataIC50: 28nM EC50:  2.90nMpH: 7.4 T: 2°CAssay Description:Radioligand binding assay was performed by using 96-well microtiterplates containing ER, 17beta-estradiol, and the test compound to be tested and SPA...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/16/2008
Entry Details Article
PubMed
TargetEstrogen receptor(Human)
Novartis Pharmaceuticals

LigandPNGBDBM20588(1-methyl-2-phenyl-1-{4-[2-(piperidin-1-yl)ethoxy]p...)
Affinity DataIC50: 29nM EC50:  2.60nMpH: 7.4 T: 2°CAssay Description:Radioligand binding assay was performed by using 96-well microtiterplates containing ER, 17beta-estradiol, and the test compound to be tested and SPA...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/16/2008
Entry Details Article
PubMed
TargetEstrogen receptor(Human)
Novartis Pharmaceuticals

LigandPNGBDBM20598(2-(3-hydroxyphenyl)-1-methyl-1-{4-[2-(pyrrolidin-1...)
Affinity DataIC50: 31nM EC50:  0.600nMpH: 7.4 T: 2°CAssay Description:Radioligand binding assay was performed by using 96-well microtiterplates containing ER, 17beta-estradiol, and the test compound to be tested and SPA...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/16/2008
Entry Details Article
PubMed
TargetEstrogen receptor(Human)
Novartis Pharmaceuticals

LigandPNGBDBM20590(1-methyl-2-(4-methylphenyl)-1-{4-[2-(pyrrolidin-1-...)
Affinity DataIC50: 31nM EC50:  3.5nMpH: 7.4 T: 2°CAssay Description:Radioligand binding assay was performed by using 96-well microtiterplates containing ER, 17beta-estradiol, and the test compound to be tested and SPA...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/16/2008
Entry Details Article
PubMed
TargetEstrogen receptor(Human)
Novartis Pharmaceuticals

LigandPNGBDBM20592(2-(4-fluorophenyl)-1-methyl-1-{4-[2-(pyrrolidin-1-...)
Affinity DataIC50: 31nM EC50:  1.60nMpH: 7.4 T: 2°CAssay Description:Radioligand binding assay was performed by using 96-well microtiterplates containing ER, 17beta-estradiol, and the test compound to be tested and SPA...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/16/2008
Entry Details Article
PubMed
TargetEstrogen receptor(Human)
Novartis Pharmaceuticals

LigandPNGBDBM20599(2-(3-hydroxyphenyl)-1-methyl-1-{4-[2-(piperidin-1-...)
Affinity DataIC50: 34nM EC50:  0.700nMpH: 7.4 T: 2°CAssay Description:Radioligand binding assay was performed by using 96-well microtiterplates containing ER, 17beta-estradiol, and the test compound to be tested and SPA...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/16/2008
Entry Details Article
PubMed
TargetEstrogen receptor(Human)
Novartis Pharmaceuticals

LigandPNGBDBM20595(2-(4-chlorophenyl)-1-methyl-1-{4-[2-(piperidin-1-y...)
Affinity DataIC50: 35nM EC50:  3.10nMpH: 7.4 T: 2°CAssay Description:Radioligand binding assay was performed by using 96-well microtiterplates containing ER, 17beta-estradiol, and the test compound to be tested and SPA...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/16/2008
Entry Details Article
PubMed
TargetEstrogen receptor(Human)
Novartis Pharmaceuticals

LigandPNGBDBM20593(2-(4-fluorophenyl)-1-methyl-1-{4-[2-(piperidin-1-y...)
Affinity DataIC50: 38nM EC50:  1.90nMpH: 7.4 T: 2°CAssay Description:Radioligand binding assay was performed by using 96-well microtiterplates containing ER, 17beta-estradiol, and the test compound to be tested and SPA...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/16/2008
Entry Details Article
PubMed
TargetEstrogen receptor(Human)
Novartis Pharmaceuticals

LigandPNGBDBM20587(1-methyl-2-phenyl-1-{4-[2-(pyrrolidin-1-yl)ethoxy]...)
Affinity DataIC50: 38nM EC50:  1.80nMpH: 7.4 T: 2°CAssay Description:Radioligand binding assay was performed by using 96-well microtiterplates containing ER, 17beta-estradiol, and the test compound to be tested and SPA...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/16/2008
Entry Details Article
PubMed
TargetEstrogen receptor(Human)
Novartis Pharmaceuticals

LigandPNGBDBM20600(2-(3-fluorophenyl)-1-methyl-1-{4-[2-(pyrrolidin-1-...)
Affinity DataIC50: 39nM EC50:  3nMpH: 7.4 T: 2°CAssay Description:Radioligand binding assay was performed by using 96-well microtiterplates containing ER, 17beta-estradiol, and the test compound to be tested and SPA...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/16/2008
Entry Details Article
PubMed
TargetEstrogen receptor(Human)
Novartis Pharmaceuticals

LigandPNGBDBM20596(1-methyl-2-[4-(propan-2-yl)phenyl]-1-{4-[2-(pyrrol...)
Affinity DataIC50: 44nM EC50:  2.60nMpH: 7.4 T: 2°CAssay Description:Radioligand binding assay was performed by using 96-well microtiterplates containing ER, 17beta-estradiol, and the test compound to be tested and SPA...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/16/2008
Entry Details Article
PubMed
TargetEstrogen receptor(Human)
Novartis Pharmaceuticals

LigandPNGBDBM20603(1-methyl-1-{4-[2-(piperidin-1-yl)ethoxy]phenyl}-2-...)
Affinity DataIC50: 46nM EC50:  16.1nMpH: 7.4 T: 2°CAssay Description:Radioligand binding assay was performed by using 96-well microtiterplates containing ER, 17beta-estradiol, and the test compound to be tested and SPA...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/16/2008
Entry Details Article
PubMed
TargetEstrogen receptor(Human)
Novartis Pharmaceuticals

LigandPNGBDBM20602(2-(3-chlorophenyl)-1-methyl-1-{4-[2-(piperidin-1-y...)
Affinity DataIC50: 49nM EC50:  4.5nMpH: 7.4 T: 2°CAssay Description:Radioligand binding assay was performed by using 96-well microtiterplates containing ER, 17beta-estradiol, and the test compound to be tested and SPA...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/16/2008
Entry Details Article
PubMed
TargetEstrogen receptor(Human)
Novartis Pharmaceuticals

LigandPNGBDBM20589(1-{4-[2-(azepan-1-yl)ethoxy]phenyl}-1-methyl-2-phe...)
Affinity DataIC50: 56nM EC50:  1.5nMpH: 7.4 T: 2°CAssay Description:Radioligand binding assay was performed by using 96-well microtiterplates containing ER, 17beta-estradiol, and the test compound to be tested and SPA...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/16/2008
Entry Details Article
PubMed
TargetEstrogen receptor(Human)
Novartis Pharmaceuticals

LigandPNGBDBM20601(2-(3-chlorophenyl)-1-methyl-1-{4-[2-(pyrrolidin-1-...)
Affinity DataIC50: 66nM EC50:  2.90nMpH: 7.4 T: 2°CAssay Description:Radioligand binding assay was performed by using 96-well microtiterplates containing ER, 17beta-estradiol, and the test compound to be tested and SPA...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/16/2008
Entry Details Article
PubMed
TargetEstrogen receptor(Human)
Novartis Pharmaceuticals

LigandPNGBDBM20605(2-[3-(dimethylamino)phenyl]-1-methyl-1-{4-[2-(pipe...)
Affinity DataIC50: 71nM EC50:  19.8nMpH: 7.4 T: 2°CAssay Description:Radioligand binding assay was performed by using 96-well microtiterplates containing ER, 17beta-estradiol, and the test compound to be tested and SPA...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/16/2008
Entry Details Article
PubMed
TargetEstrogen receptor(Human)
Novartis Pharmaceuticals

LigandPNGBDBM20597(1-methyl-1-{4-[2-(piperidin-1-yl)ethoxy]phenyl}-2-...)
Affinity DataIC50: 71nM EC50:  5.20nMpH: 7.4 T: 2°CAssay Description:Radioligand binding assay was performed by using 96-well microtiterplates containing ER, 17beta-estradiol, and the test compound to be tested and SPA...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/16/2008
Entry Details Article
PubMed
TargetEstrogen receptor(Human)
Novartis Pharmaceuticals

LigandPNGBDBM20604(2-[3-(dimethylamino)phenyl]-1-methyl-1-{4-[2-(pyrr...)
Affinity DataIC50: 94nM EC50:  19nMpH: 7.4 T: 2°CAssay Description:Radioligand binding assay was performed by using 96-well microtiterplates containing ER, 17beta-estradiol, and the test compound to be tested and SPA...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/16/2008
Entry Details Article
PubMed
TargetEstrogen receptor beta(Human)
Novartis Pharmaceuticals

LigandPNGBDBM20588(1-methyl-2-phenyl-1-{4-[2-(piperidin-1-yl)ethoxy]p...)
Affinity DataIC50: 104nM EC50:  83nMT: 2°CAssay Description:Radioligand binding assay was performed by using 96-well microtiterplates containing ER, 17beta-estradiol, and the test compound to be tested and SPA...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/16/2008
Entry Details Article
PubMed
TargetEstrogen receptor beta(Human)
Novartis Pharmaceuticals

LigandPNGBDBM20600(2-(3-fluorophenyl)-1-methyl-1-{4-[2-(pyrrolidin-1-...)
Affinity DataIC50: 123nM EC50:  198nMT: 2°CAssay Description:Radioligand binding assay was performed by using 96-well microtiterplates containing ER, 17beta-estradiol, and the test compound to be tested and SPA...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/16/2008
Entry Details Article
PubMed
TargetEstrogen receptor beta(Human)
Novartis Pharmaceuticals

LigandPNGBDBM20585(2-phenyl-1-{4-[2-(pyrrolidin-1-yl)ethoxy]phenyl}-1...)
Affinity DataIC50: 166nM EC50:  291nMT: 2°CAssay Description:Radioligand binding assay was performed by using 96-well microtiterplates containing ER, 17beta-estradiol, and the test compound to be tested and SPA...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/16/2008
Entry Details Article
PubMed
TargetEstrogen receptor beta(Human)
Novartis Pharmaceuticals

LigandPNGBDBM20598(2-(3-hydroxyphenyl)-1-methyl-1-{4-[2-(pyrrolidin-1...)
Affinity DataIC50: 190nM EC50:  33nMT: 2°CAssay Description:Radioligand binding assay was performed by using 96-well microtiterplates containing ER, 17beta-estradiol, and the test compound to be tested and SPA...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/16/2008
Entry Details Article
PubMed
TargetEstrogen receptor beta(Human)
Novartis Pharmaceuticals

LigandPNGBDBM20589(1-{4-[2-(azepan-1-yl)ethoxy]phenyl}-1-methyl-2-phe...)
Affinity DataIC50: 200nM EC50:  80nMT: 2°CAssay Description:Radioligand binding assay was performed by using 96-well microtiterplates containing ER, 17beta-estradiol, and the test compound to be tested and SPA...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/16/2008
Entry Details Article
PubMed
TargetEstrogen receptor beta(Human)
Novartis Pharmaceuticals

LigandPNGBDBM20592(2-(4-fluorophenyl)-1-methyl-1-{4-[2-(pyrrolidin-1-...)
Affinity DataIC50: 204nM EC50:  82nMT: 2°CAssay Description:Radioligand binding assay was performed by using 96-well microtiterplates containing ER, 17beta-estradiol, and the test compound to be tested and SPA...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/16/2008
Entry Details Article
PubMed
TargetEstrogen receptor beta(Human)
Novartis Pharmaceuticals

LigandPNGBDBM20587(1-methyl-2-phenyl-1-{4-[2-(pyrrolidin-1-yl)ethoxy]...)
Affinity DataIC50: 227nM EC50:  83nMT: 2°CAssay Description:Radioligand binding assay was performed by using 96-well microtiterplates containing ER, 17beta-estradiol, and the test compound to be tested and SPA...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/16/2008
Entry Details Article
PubMed
TargetEstrogen receptor beta(Human)
Novartis Pharmaceuticals

LigandPNGBDBM19441(Evista | CHEMBL81 | Keoxifene | Raloxifene, 6 | RA...)
Affinity DataIC50: 260nM EC50:  341nMT: 2°CAssay Description:Radioligand binding assay was performed by using 96-well microtiterplates containing ER, 17beta-estradiol, and the test compound to be tested and SPA...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/16/2008
Entry Details Article
PubMed
TargetEstrogen receptor beta(Human)
Novartis Pharmaceuticals

LigandPNGBDBM20601(2-(3-chlorophenyl)-1-methyl-1-{4-[2-(pyrrolidin-1-...)
Affinity DataIC50: 272nM EC50:  106nMT: 2°CAssay Description:Radioligand binding assay was performed by using 96-well microtiterplates containing ER, 17beta-estradiol, and the test compound to be tested and SPA...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/16/2008
Entry Details Article
PubMed
TargetEstrogen receptor beta(Human)
Novartis Pharmaceuticals

LigandPNGBDBM20602(2-(3-chlorophenyl)-1-methyl-1-{4-[2-(piperidin-1-y...)
Affinity DataIC50: 284nM EC50:  159nMT: 2°CAssay Description:Radioligand binding assay was performed by using 96-well microtiterplates containing ER, 17beta-estradiol, and the test compound to be tested and SPA...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/16/2008
Entry Details Article
PubMed
TargetEstrogen receptor(Human)
Novartis Pharmaceuticals

LigandPNGBDBM20584(1-(4-fluorophenyl)-2-phenyl-1,2,3,4-tetrahydroisoq...)
Affinity DataIC50: 285nMpH: 7.4 T: 2°CAssay Description:Radioligand binding assay was performed by using 96-well microtiterplates containing ER, 17beta-estradiol, and the test compound to be tested and SPA...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/16/2008
Entry Details Article
PubMed
TargetEstrogen receptor beta(Human)
Novartis Pharmaceuticals

LigandPNGBDBM20594(2-(4-chlorophenyl)-1-methyl-1-{4-[2-(pyrrolidin-1-...)
Affinity DataIC50: 302nM EC50:  531nMT: 2°CAssay Description:Radioligand binding assay was performed by using 96-well microtiterplates containing ER, 17beta-estradiol, and the test compound to be tested and SPA...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/16/2008
Entry Details Article
PubMed
TargetEstrogen receptor beta(Human)
Novartis Pharmaceuticals

LigandPNGBDBM20599(2-(3-hydroxyphenyl)-1-methyl-1-{4-[2-(piperidin-1-...)
Affinity DataIC50: 304nM EC50:  47nMT: 2°CAssay Description:Radioligand binding assay was performed by using 96-well microtiterplates containing ER, 17beta-estradiol, and the test compound to be tested and SPA...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/16/2008
Entry Details Article
PubMed
TargetEstrogen receptor beta(Human)
Novartis Pharmaceuticals

LigandPNGBDBM20593(2-(4-fluorophenyl)-1-methyl-1-{4-[2-(piperidin-1-y...)
Affinity DataIC50: 317nM EC50:  92nMT: 2°CAssay Description:Radioligand binding assay was performed by using 96-well microtiterplates containing ER, 17beta-estradiol, and the test compound to be tested and SPA...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/16/2008
Entry Details Article
PubMed
TargetEstrogen receptor beta(Human)
Novartis Pharmaceuticals

LigandPNGBDBM20586(2-phenyl-1-{4-[2-(piperidin-1-yl)ethoxy]phenyl}-1,...)
Affinity DataIC50: 346nM EC50:  289nMT: 2°CAssay Description:Radioligand binding assay was performed by using 96-well microtiterplates containing ER, 17beta-estradiol, and the test compound to be tested and SPA...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/16/2008
Entry Details Article
PubMed
TargetEstrogen receptor beta(Human)
Novartis Pharmaceuticals

LigandPNGBDBM20590(1-methyl-2-(4-methylphenyl)-1-{4-[2-(pyrrolidin-1-...)
Affinity DataIC50: 354nM EC50:  448nMT: 2°CAssay Description:Radioligand binding assay was performed by using 96-well microtiterplates containing ER, 17beta-estradiol, and the test compound to be tested and SPA...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/16/2008
Entry Details Article
PubMed
TargetEstrogen receptor beta(Human)
Novartis Pharmaceuticals

LigandPNGBDBM20595(2-(4-chlorophenyl)-1-methyl-1-{4-[2-(piperidin-1-y...)
Affinity DataIC50: 396nM EC50:  552nMT: 2°CAssay Description:Radioligand binding assay was performed by using 96-well microtiterplates containing ER, 17beta-estradiol, and the test compound to be tested and SPA...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/16/2008
Entry Details Article
PubMed
TargetEstrogen receptor beta(Human)
Novartis Pharmaceuticals

LigandPNGBDBM20591(1-methyl-2-(4-methylphenyl)-1-{4-[2-(piperidin-1-y...)
Affinity DataIC50: 421nM EC50:  486nMT: 2°CAssay Description:Radioligand binding assay was performed by using 96-well microtiterplates containing ER, 17beta-estradiol, and the test compound to be tested and SPA...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/16/2008
Entry Details Article
PubMed
TargetEstrogen receptor beta(Human)
Novartis Pharmaceuticals

LigandPNGBDBM20584(1-(4-fluorophenyl)-2-phenyl-1,2,3,4-tetrahydroisoq...)
Affinity DataIC50: 421nMT: 2°CAssay Description:Radioligand binding assay was performed by using 96-well microtiterplates containing ER, 17beta-estradiol, and the test compound to be tested and SPA...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/16/2008
Entry Details Article
PubMed
TargetEstrogen receptor beta(Human)
Novartis Pharmaceuticals

LigandPNGBDBM20603(1-methyl-1-{4-[2-(piperidin-1-yl)ethoxy]phenyl}-2-...)
Affinity DataIC50: 1.11E+3nM EC50:  492nMT: 2°CAssay Description:Radioligand binding assay was performed by using 96-well microtiterplates containing ER, 17beta-estradiol, and the test compound to be tested and SPA...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/16/2008
Entry Details Article
PubMed
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