Compile Data Set for Download or QSAR
Report error Found 9 Enz. Inhib. hit(s) with all data for entry = 1404
TargetCasein kinase II subunit alpha(Human)
University of Padova

LigandPNGBDBM11322(N-(3-chlorophenyl)-4-(2-{[2-(1H-imidazol-4-yl)ethy...)
Affinity DataIC50: 3.20E+3nMpH: 7.5 T: 2°CAssay Description:In vitro kinase assay using purified enzyme, was incubated at room temperature with substrate, and test compounds in the presence of 100 uM ATP/ [gam...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/26/2006
Entry Details Article
PubMed
TargetCasein kinase II subunit alpha(Human)
University of Padova

LigandPNGBDBM11320(3-{[4-(2-{[3-(1,1,2,2-tetrafluoroethoxy)phenyl]ami...)
Affinity DataIC50: 3.60E+3nMpH: 7.5 T: 2°CAssay Description:In vitro kinase assay using purified enzyme, was incubated at room temperature with substrate, and test compounds in the presence of 100 uM ATP/ [gam...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/26/2006
Entry Details Article
PubMed
TargetCasein kinase II subunit alpha(Human)
University of Padova

LigandPNGBDBM11321(4-{2-[(2-aminoethyl)amino]pyridin-4-yl}-N-(3-chlor...)
Affinity DataIC50: 9.60E+3nMpH: 7.5 T: 2°CAssay Description:In vitro kinase assay using purified enzyme, was incubated at room temperature with substrate, and test compounds in the presence of 100 uM ATP/ [gam...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/26/2006
Entry Details Article
PubMed
TargetCasein kinase II subunit alpha(Human)
University of Padova

LigandPNGBDBM11319(IQA | 2-{8-oxo-1,9-diazatetracyclo[8.7.0.0^{2,7}.0...)
Affinity DataKi:  170nM ΔG°:  -38.2kJ/mole IC50: 390nMpH: 7.5 T: 2°CAssay Description:In vitro kinase assay using purified enzyme, was incubated at room temperature with substrate, and test compounds in the presence of 100 uM ATP/ [gam...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/26/2006
Entry Details Article
PubMed
TargetCasein kinase II subunit alpha(Human)
University of Padova

LigandPNGBDBM11323(CHEMBL177820 | 4,5,6,7-tetrabromo-1H-1,2,3-benzotr...)
Affinity DataKi:  400nM ΔG°:  -36.2kJ/mole IC50: 500nMpH: 7.5 T: 2°CAssay Description:In vitro kinase assay using purified enzyme, was incubated at room temperature with substrate, and test compounds in the presence of 100 uM ATP/ [gam...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/26/2006
Entry Details Article
PubMed
TargetCasein kinase II subunit alpha(Human)
University of Padova

LigandPNGBDBM7458(Naringenin, 18 | 5,7-dihydroxy-2-(4-hydroxyphenyl)...)
Affinity DataKi:  740nM ΔG°:  -34.6kJ/molepH: 7.5 T: 2°CAssay Description:In vitro kinase assay using purified enzyme, was incubated at room temperature with substrate, and test compounds in the presence of 100 uM ATP/ [gam...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/26/2006
Entry Details Article
PubMedPDB3D3D Structure (crystal)
TargetCasein kinase II subunit alpha(Human)
University of Padova

LigandPNGBDBM7460(2-(3,4-dihydroxyphenyl)-3,5,7-trihydroxy-chromone;...)
Affinity DataKi:  1.18E+3nM ΔG°:  -33.5kJ/molepH: 7.5 T: 2°CAssay Description:In vitro kinase assay using purified enzyme, was incubated at room temperature with substrate, and test compounds in the presence of 100 uM ATP/ [gam...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/26/2006
Entry Details Article
PubMed
TargetCasein kinase II subunit alpha(Human)
University of Padova

LigandPNGBDBM11318(1,3,8-trihydroxy-6-methylanthra-9,10-quinone | CHE...)
Affinity DataKi:  1.85E+3nM ΔG°:  -32.4kJ/mole IC50: 890nMpH: 7.5 T: 2°CAssay Description:In vitro kinase assay using purified enzyme, was incubated at room temperature with substrate, and test compounds in the presence of 100 uM ATP/ [gam...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/26/2006
Entry Details Article
PubMedPDB3D3D Structure (crystal)
TargetCasein kinase II subunit alpha(Human)
University of Padova

LigandPNGBDBM11324(CHEMBL375530 | (2R,3R,4S,5R)-2-(5,6-dichloro-1H-1,...)
Affinity DataKi:  4.50E+3nM ΔG°:  -30.2kJ/molepH: 7.5 T: 2°CAssay Description:In vitro kinase assay using purified enzyme, was incubated at room temperature with substrate, and test compounds in the presence of 100 uM ATP/ [gam...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/26/2006
Entry Details Article
PubMed