Compile Data Set for Download or QSAR
Report error Found 191 Enz. Inhib. hit(s) with all data for entry = 1816
TargetSerine protease 1(Bovine)
Celera

LigandPNGBDBM14338(2-{5-[amino(iminiumyl)methyl]-1H-indol-2-yl}-4-nit...)
Affinity DataKi:  1.30nMAssay Description:Each enzyme was assayed with a set of different concentrations of each inhibitor. After addition of the appropriate substrate, the rate of hydrolysis...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/12/2007
Entry Details Article
PubMed
LigandPNGBDBM14352(2-{5-[amino(iminiumyl)methyl]-6-chloro-1H-indol-2-...)
Affinity DataKi:  2.20nMAssay Description:Each enzyme was assayed with a set of different concentrations of each inhibitor. After addition of the appropriate substrate, the rate of hydrolysis...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/12/2007
Entry Details Article
PubMed
LigandPNGBDBM14351(2-{5-[amino(iminiumyl)methyl]-6-chloro-1H-indol-2-...)
Affinity DataKi:  2.60nMAssay Description:Each enzyme was assayed with a set of different concentrations of each inhibitor. After addition of the appropriate substrate, the rate of hydrolysis...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/12/2007
Entry Details Article
PubMed
LigandPNGBDBM14354(2-{5-[amino(iminiumyl)methyl]-1H-indol-2-yl}-4-(di...)
Affinity DataKi:  3.20nMAssay Description:Each enzyme was assayed with a set of different concentrations of each inhibitor. After addition of the appropriate substrate, the rate of hydrolysis...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/12/2007
Entry Details Article
PubMed
TargetSerine protease 1(Bovine)
Celera

LigandPNGBDBM14142(CRA-8696 | CA-04 | 3-{5-[AMINO(IMINIO)METHYL]-1H-I...)
Affinity DataKi:  11nM ΔG°:  -45.0kJ/molepH: 7.45 T: 2°CAssay Description:Each enzyme was assayed with a set of different concentrations of each inhibitor. After addition of the appropriate substrate, the rate of hydrolysis...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/12/2007
Entry Details Article
PubMed
TargetSerine protease 1(Bovine)
Celera

LigandPNGBDBM14335(2-{5-[amino(iminiumyl)methyl]-1H-indol-2-yl}-4-chl...)
Affinity DataKi:  13nMAssay Description:Each enzyme was assayed with a set of different concentrations of each inhibitor. After addition of the appropriate substrate, the rate of hydrolysis...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/12/2007
Entry Details Article
PubMed
LigandPNGBDBM14152(CA-14 | 6-CHLORO-2-(2-HYDROXY-BIPHENYL-3-YL)-1H-IN...)
Affinity DataKi:  13nMAssay Description:Each enzyme was assayed with a set of different concentrations of each inhibitor. After addition of the appropriate substrate, the rate of hydrolysis...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/12/2007
Entry Details Article
PubMed
TargetCoagulation factor X(Human)
Celera

LigandPNGBDBM14338(2-{5-[amino(iminiumyl)methyl]-1H-indol-2-yl}-4-nit...)
Affinity DataKi:  13nMAssay Description:Each enzyme was assayed with a set of different concentrations of each inhibitor. After addition of the appropriate substrate, the rate of hydrolysis...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/12/2007
Entry Details Article
PubMed
TargetSerine protease 1(Bovine)
Celera

LigandPNGBDBM14337(2-{5-[amino(iminiumyl)methyl]-1H-indol-2-yl}-4-met...)
Affinity DataKi:  14nMAssay Description:Each enzyme was assayed with a set of different concentrations of each inhibitor. After addition of the appropriate substrate, the rate of hydrolysis...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/12/2007
Entry Details Article
PubMed
TargetSerine protease 1(Bovine)
Celera

LigandPNGBDBM14329(2-{5-[amino(iminiumyl)methyl]-1H-indol-2-yl}-4-met...)
Affinity DataKi:  15nM ΔG°:  -44.2kJ/molepH: 7.6 T: 2°CAssay Description:Each enzyme was assayed with a set of different concentrations of each inhibitor. After addition of the appropriate substrate, the rate of hydrolysis...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/12/2007
Entry Details Article
PubMed
LigandPNGBDBM14150(CA-12 | CRA-11417 | {amino[6-fluoro-2-(2-hydroxy-3...)
Affinity DataKi:  20nMAssay Description:Each enzyme was assayed with a set of different concentrations of each inhibitor. After addition of the appropriate substrate, the rate of hydrolysis...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/12/2007
Entry Details Article
PubMed
TargetSerine protease 1(Bovine)
Celera

LigandPNGBDBM14334(2-{5-[amino(iminiumyl)methyl]-6-chloro-1H-indol-2-...)
Affinity DataKi:  21nMAssay Description:Each enzyme was assayed with a set of different concentrations of each inhibitor. After addition of the appropriate substrate, the rate of hydrolysis...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/12/2007
Entry Details Article
PubMed
LigandPNGBDBM14338(2-{5-[amino(iminiumyl)methyl]-1H-indol-2-yl}-4-nit...)
Affinity DataKi:  25nMAssay Description:Each enzyme was assayed with a set of different concentrations of each inhibitor. After addition of the appropriate substrate, the rate of hydrolysis...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/12/2007
Entry Details Article
PubMed
TargetSerine protease 1(Bovine)
Celera

LigandPNGBDBM14344((2R)-2-(3-{5-[amino(iminiumyl)methyl]-1H-1,3-benzo...)
Affinity DataKi:  30nMAssay Description:Each enzyme was assayed with a set of different concentrations of each inhibitor. After addition of the appropriate substrate, the rate of hydrolysis...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/12/2007
Entry Details Article
PubMed
LigandPNGBDBM14353(2-{5-[amino(iminiumyl)methyl]-6-fluoro-1H-indol-2-...)
Affinity DataKi:  30nMAssay Description:Each enzyme was assayed with a set of different concentrations of each inhibitor. After addition of the appropriate substrate, the rate of hydrolysis...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/12/2007
Entry Details Article
PubMed
LigandPNGBDBM14337(2-{5-[amino(iminiumyl)methyl]-1H-indol-2-yl}-4-met...)
Affinity DataKi:  31nMAssay Description:Each enzyme was assayed with a set of different concentrations of each inhibitor. After addition of the appropriate substrate, the rate of hydrolysis...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/12/2007
Entry Details Article
PubMed
LigandPNGBDBM14350(2-{5-[amino(iminiumyl)methyl]-6-fluoro-1H-1,3-benz...)
Affinity DataKi:  33nMAssay Description:Each enzyme was assayed with a set of different concentrations of each inhibitor. After addition of the appropriate substrate, the rate of hydrolysis...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/12/2007
Entry Details Article
PubMed
TargetSerine protease 1(Human)
Celera

LigandPNGBDBM14354(2-{5-[amino(iminiumyl)methyl]-1H-indol-2-yl}-4-(di...)
Affinity DataKi:  37nMAssay Description:Each enzyme was assayed with a set of different concentrations of each inhibitor. After addition of the appropriate substrate, the rate of hydrolysis...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/12/2007
Entry Details Article
PubMed
TargetCoagulation factor X(Human)
Celera

LigandPNGBDBM14330(2-{5-[amino(iminiumyl)methyl]-1H-indol-2-yl}-6-bro...)
Affinity DataKi:  43nMAssay Description:Each enzyme was assayed with a set of different concentrations of each inhibitor. After addition of the appropriate substrate, the rate of hydrolysis...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/12/2007
Entry Details Article
PubMed
TargetCoagulation factor X(Human)
Celera

LigandPNGBDBM14349(2-{5-[amino(iminiumyl)methyl]-1H-indol-2-yl}-6-bro...)
Affinity DataKi:  43nMAssay Description:Each enzyme was assayed with a set of different concentrations of each inhibitor. After addition of the appropriate substrate, the rate of hydrolysis...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/12/2007
Entry Details Article
PubMed
TargetCoagulation factor X(Human)
Celera

LigandPNGBDBM14346((2R)-2-(3-{5-[amino(iminiumyl)methyl]-1H-indol-2-y...)
Affinity DataKi:  48nMAssay Description:Each enzyme was assayed with a set of different concentrations of each inhibitor. After addition of the appropriate substrate, the rate of hydrolysis...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/12/2007
Entry Details Article
PubMed
TargetSerine protease 1(Bovine)
Celera

LigandPNGBDBM14330(2-{5-[amino(iminiumyl)methyl]-1H-indol-2-yl}-6-bro...)
Affinity DataKi:  50nM ΔG°:  -41.3kJ/molepH: 7.02 T: 2°CAssay Description:Each enzyme was assayed with a set of different concentrations of each inhibitor. After addition of the appropriate substrate, the rate of hydrolysis...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/12/2007
Entry Details Article
PubMed
LigandPNGBDBM14349(2-{5-[amino(iminiumyl)methyl]-1H-indol-2-yl}-6-bro...)
Affinity DataKi:  50nMAssay Description:Each enzyme was assayed with a set of different concentrations of each inhibitor. After addition of the appropriate substrate, the rate of hydrolysis...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/12/2007
Entry Details Article
PubMed
TargetSerine protease 1(Bovine)
Celera

LigandPNGBDBM14144(CA-06 | 2-{5-[amino(iminiumyl)methyl]-1H-1,3-benzo...)
Affinity DataKi:  52nM ΔG°:  -41.2kJ/molepH: 7.67 T: 2°CAssay Description:Each enzyme was assayed with a set of different concentrations of each inhibitor. After addition of the appropriate substrate, the rate of hydrolysis...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/12/2007
Entry Details Article
PubMed
TargetCoagulation factor X(Human)
Celera

LigandPNGBDBM14354(2-{5-[amino(iminiumyl)methyl]-1H-indol-2-yl}-4-(di...)
Affinity DataKi:  52nMAssay Description:Each enzyme was assayed with a set of different concentrations of each inhibitor. After addition of the appropriate substrate, the rate of hydrolysis...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/12/2007
Entry Details Article
PubMed
LigandPNGBDBM14330(2-{5-[amino(iminiumyl)methyl]-1H-indol-2-yl}-6-bro...)
Affinity DataKi:  64nMAssay Description:Each enzyme was assayed with a set of different concentrations of each inhibitor. After addition of the appropriate substrate, the rate of hydrolysis...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/12/2007
Entry Details Article
PubMed
TargetCoagulation factor X(Human)
Celera

LigandPNGBDBM14348(2-{5-[amino(iminiumyl)methyl]-1H-indol-2-yl}-6-chl...)
Affinity DataKi:  64nMAssay Description:Each enzyme was assayed with a set of different concentrations of each inhibitor. After addition of the appropriate substrate, the rate of hydrolysis...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/12/2007
Entry Details Article
PubMed
TargetSerine protease 1(Bovine)
Celera

LigandPNGBDBM14332(2-{5-[amino(iminiumyl)methyl]-1H-indol-2-yl}-6-(cy...)
Affinity DataKi:  68nM ΔG°:  -40.5kJ/molepH: 8.06 T: 2°CAssay Description:Each enzyme was assayed with a set of different concentrations of each inhibitor. After addition of the appropriate substrate, the rate of hydrolysis...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/12/2007
Entry Details Article
PubMed
LigandPNGBDBM14142(CRA-8696 | CA-04 | 3-{5-[AMINO(IMINIO)METHYL]-1H-I...)
Affinity DataKi:  72nMAssay Description:Each enzyme was assayed with a set of different concentrations of each inhibitor. After addition of the appropriate substrate, the rate of hydrolysis...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/12/2007
Entry Details Article
PubMed
TargetSerine protease 1(Bovine)
Celera

LigandPNGBDBM14325(2-{5-[amino(iminiumyl)methyl]-1H-1,3-benzodiazol-2...)
Affinity DataKi:  74nM ΔG°:  -40.3kJ/molepH: 7.5 T: 2°CAssay Description:Each enzyme was assayed with a set of different concentrations of each inhibitor. After addition of the appropriate substrate, the rate of hydrolysis...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/12/2007
Entry Details Article
PubMed
TargetSerine protease 1(Human)
Celera

LigandPNGBDBM14338(2-{5-[amino(iminiumyl)methyl]-1H-indol-2-yl}-4-nit...)
Affinity DataKi:  80nMAssay Description:Each enzyme was assayed with a set of different concentrations of each inhibitor. After addition of the appropriate substrate, the rate of hydrolysis...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/12/2007
Entry Details Article
PubMed
LigandPNGBDBM14342((2R)-2-(3-{5-[amino(iminiumyl)methyl]-1H-1,3-benzo...)
Affinity DataKi:  85nMAssay Description:Each enzyme was assayed with a set of different concentrations of each inhibitor. After addition of the appropriate substrate, the rate of hydrolysis...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/12/2007
Entry Details Article
PubMed
LigandPNGBDBM14348(2-{5-[amino(iminiumyl)methyl]-1H-indol-2-yl}-6-chl...)
Affinity DataKi:  95nMAssay Description:Each enzyme was assayed with a set of different concentrations of each inhibitor. After addition of the appropriate substrate, the rate of hydrolysis...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/12/2007
Entry Details Article
PubMed
TargetSerine protease 1(Bovine)
Celera

LigandPNGBDBM14152(CA-14 | 6-CHLORO-2-(2-HYDROXY-BIPHENYL-3-YL)-1H-IN...)
Affinity DataKi:  100nM ΔG°:  -39.6kJ/molepH: 7.72 T: 2°CAssay Description:Each enzyme was assayed with a set of different concentrations of each inhibitor. After addition of the appropriate substrate, the rate of hydrolysis...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/12/2007
Entry Details Article
PubMed
TargetCoagulation factor X(Human)
Celera

LigandPNGBDBM14356((2R)-2-(3-{5-[amino(iminiumyl)methyl]-1H-indol-2-y...)
Affinity DataKi:  100nMAssay Description:Each enzyme was assayed with a set of different concentrations of each inhibitor. After addition of the appropriate substrate, the rate of hydrolysis...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/12/2007
Entry Details Article
PubMed
TargetProthrombin(Human)
Celera

LigandPNGBDBM14338(2-{5-[amino(iminiumyl)methyl]-1H-indol-2-yl}-4-nit...)
Affinity DataKi:  110nMAssay Description:Each enzyme was assayed with a set of different concentrations of each inhibitor. After addition of the appropriate substrate, the rate of hydrolysis...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/12/2007
Entry Details Article
PubMed
LigandPNGBDBM14148(CA-10 | 2-{5-[amino(iminiumyl)methyl]-6-fluoro-1H-...)
Affinity DataKi:  110nMAssay Description:Each enzyme was assayed with a set of different concentrations of each inhibitor. After addition of the appropriate substrate, the rate of hydrolysis...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/12/2007
Entry Details Article
PubMed
TargetCoagulation factor X(Human)
Celera

LigandPNGBDBM14358(4-(2-aminiumylethyl)-2-{5-[amino(iminiumyl)methyl]...)
Affinity DataKi:  110nMAssay Description:Each enzyme was assayed with a set of different concentrations of each inhibitor. After addition of the appropriate substrate, the rate of hydrolysis...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/12/2007
Entry Details Article
PubMed
TargetSerine protease 1(Bovine)
Celera

LigandPNGBDBM14145(2-{5-[amino(iminiumyl)methyl]-1H-1,3-benzodiazol-2...)
Affinity DataKi:  120nM ΔG°:  -39.1kJ/molepH: 7.45 T: 2°CAssay Description:Each enzyme was assayed with a set of different concentrations of each inhibitor. After addition of the appropriate substrate, the rate of hydrolysis...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/12/2007
Entry Details Article
PubMed
LigandPNGBDBM14340((2R)-2-(3-{5-[amino(iminiumyl)methyl]-1H-1,3-benzo...)
Affinity DataKi:  120nMAssay Description:Each enzyme was assayed with a set of different concentrations of each inhibitor. After addition of the appropriate substrate, the rate of hydrolysis...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/12/2007
Entry Details Article
PubMed
TargetSerine protease 1(Human)
Celera

LigandPNGBDBM14353(2-{5-[amino(iminiumyl)methyl]-6-fluoro-1H-indol-2-...)
Affinity DataKi:  130nMAssay Description:Each enzyme was assayed with a set of different concentrations of each inhibitor. After addition of the appropriate substrate, the rate of hydrolysis...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/12/2007
Entry Details Article
PubMed
TargetSerine protease 1(Human)
Celera

LigandPNGBDBM14337(2-{5-[amino(iminiumyl)methyl]-1H-indol-2-yl}-4-met...)
Affinity DataKi:  130nMAssay Description:Each enzyme was assayed with a set of different concentrations of each inhibitor. After addition of the appropriate substrate, the rate of hydrolysis...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/12/2007
Entry Details Article
PubMed
TargetProthrombin(Human)
Celera

LigandPNGBDBM14330(2-{5-[amino(iminiumyl)methyl]-1H-indol-2-yl}-6-bro...)
Affinity DataKi:  140nMAssay Description:Each enzyme was assayed with a set of different concentrations of each inhibitor. After addition of the appropriate substrate, the rate of hydrolysis...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/12/2007
Entry Details Article
PubMed
TargetCoagulation factor X(Human)
Celera

LigandPNGBDBM14337(2-{5-[amino(iminiumyl)methyl]-1H-indol-2-yl}-4-met...)
Affinity DataKi:  140nMAssay Description:Each enzyme was assayed with a set of different concentrations of each inhibitor. After addition of the appropriate substrate, the rate of hydrolysis...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/12/2007
Entry Details Article
PubMed
LigandPNGBDBM14334(2-{5-[amino(iminiumyl)methyl]-6-chloro-1H-indol-2-...)
Affinity DataKi:  160nMAssay Description:Each enzyme was assayed with a set of different concentrations of each inhibitor. After addition of the appropriate substrate, the rate of hydrolysis...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/12/2007
Entry Details Article
PubMed
TargetCoagulation factor X(Human)
Celera

LigandPNGBDBM14142(CRA-8696 | CA-04 | 3-{5-[AMINO(IMINIO)METHYL]-1H-I...)
Affinity DataKi:  160nMAssay Description:Each enzyme was assayed with a set of different concentrations of each inhibitor. After addition of the appropriate substrate, the rate of hydrolysis...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/12/2007
Entry Details Article
PubMed
TargetSerine protease 1(Bovine)
Celera

LigandPNGBDBM14331(2-{5-[amino(iminiumyl)methyl]-1H-1,3-benzodiazol-2...)
Affinity DataKi:  170nM ΔG°:  -38.2kJ/molepH: 6.7 T: 2°CAssay Description:Each enzyme was assayed with a set of different concentrations of each inhibitor. After addition of the appropriate substrate, the rate of hydrolysis...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/12/2007
Entry Details Article
PubMed
TargetSerine protease 1(Bovine)
Celera

LigandPNGBDBM14342((2R)-2-(3-{5-[amino(iminiumyl)methyl]-1H-1,3-benzo...)
Affinity DataKi:  170nMAssay Description:Each enzyme was assayed with a set of different concentrations of each inhibitor. After addition of the appropriate substrate, the rate of hydrolysis...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/12/2007
Entry Details Article
PubMed
TargetCoagulation factor X(Human)
Celera

LigandPNGBDBM14329(2-{5-[amino(iminiumyl)methyl]-1H-indol-2-yl}-4-met...)
Affinity DataKi:  180nMAssay Description:Each enzyme was assayed with a set of different concentrations of each inhibitor. After addition of the appropriate substrate, the rate of hydrolysis...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/12/2007
Entry Details Article
PubMed
TargetSerine protease 1(Bovine)
Celera

LigandPNGBDBM14150(CA-12 | CRA-11417 | {amino[6-fluoro-2-(2-hydroxy-3...)
Affinity DataKi:  190nMAssay Description:Each enzyme was assayed with a set of different concentrations of each inhibitor. After addition of the appropriate substrate, the rate of hydrolysis...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/12/2007
Entry Details Article
PubMed
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