Compile Data Set for Download or QSAR
Report error Found 50 Enz. Inhib. hit(s) with all data for entry = 50037244
TargetProtein kinase C alpha type(Human)
Northwestern University

Curated by ChEMBL
LigandPNGBDBM2681(3-{1-[3-(dimethylamino)propyl]-1H-indol-3-yl}-4-(1...)
Affinity DataIC50: 20nMAssay Description:Inhibition of Protein kinase C alphaMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/30/2012
Entry Details Article
PubMed
TargetProtein kinase C alpha type(Human)
Northwestern University

Curated by ChEMBL
LigandPNGBDBM3175(Bisindolylmaleimide 11b | Ro 31-8220 | CHEMBL6291 ...)
Affinity DataIC50: 33nMAssay Description:Inhibition of Protein kinase C alphaMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/30/2012
Entry Details Article
PubMed
TargetMitogen-activated protein kinase 11/12/13/14(Human)
Northwestern University

Curated by ChEMBL
LigandPNGBDBM13336(4-{4-(4-fluorophenyl)-2-[4-(methylsulfinyl)phenyl]...)
Affinity DataIC50: 50nMAssay Description:Inhibition of Mitogen-activated protein kinase p38More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/30/2012
Entry Details Article
PubMed
TargetSerine/threonine-protein kinase N2(Human)
Northwestern University

Curated by ChEMBL
LigandPNGBDBM14029(4-[(1R)-1-aminoethyl]-N-(pyridin-4-yl)cyclohexane-...)
Affinity DataIC50: 600nMAssay Description:Inhibition of Protein kinase C related kinase 2 (PRK2)More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/30/2012
Entry Details Article
PubMed
TargetMalate dehydrogenase(Thermus thermophilus)
Northwestern University

Curated by ChEMBL
LigandPNGBDBM50126829((E)-1-(6-(3-acetyl-2,4,6-trihydroxy-5-methylbenzyl...)
Affinity DataIC50: 700nMAssay Description:Inhibitory activity against malate dehydrogenase (MDH) from Thermus flavusMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/30/2012
Entry Details Article
PubMed
TargetRho-associated protein kinase 2(Human)
Northwestern University

Curated by ChEMBL
LigandPNGBDBM14029(4-[(1R)-1-aminoethyl]-N-(pyridin-4-yl)cyclohexane-...)
Affinity DataIC50: 700nMAssay Description:Inhibition of Protein kinase ROCK2 (ROCKII)More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/30/2012
Entry Details Article
PubMed
TargetProstaglandin G/H synthase 1(Human)
Northwestern University

Curated by ChEMBL
LigandPNGBDBM50108771(2-(2-Amino-3-methoxy-phenyl)-chromen-4-one | PD-98...)
Affinity DataIC50: 1.00E+3nMAssay Description:Inhibitory activity against Prostaglandin G/H synthase 1 (COX-1)More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/30/2012
Entry Details Article
PubMed
TargetDNA-dependent protein kinase catalytic subunit(Human)
Northwestern University

Curated by ChEMBL
LigandPNGBDBM50336799(Suramin hexasodium | Germanin | suramin | 8,8'-[Ca...)
Affinity DataIC50: 1.70E+3nMAssay Description:Inhibitory activity against DNA-DNA dependent protein kinase (DNA-PK)More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/30/2012
Entry Details Article
PubMed
TargetSerine/threonine-protein kinase N1(Human)
Northwestern University

Curated by ChEMBL
LigandPNGBDBM14027(AT877 | CHEMBL38380 | 5-(1,4-diazepan-1-ylsulfonyl...)
Affinity DataIC50: 1.70E+3nMAssay Description:Inhibition of Protein kinase C related kinase 1 (PRK1)More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/30/2012
Entry Details Article
PubMed
TargetMAP kinase-activated protein kinase 5(Human)
Northwestern University

Curated by ChEMBL
LigandPNGBDBM50126829((E)-1-(6-(3-acetyl-2,4,6-trihydroxy-5-methylbenzyl...)
Affinity DataIC50: 1.90E+3nMAssay Description:Inhibition of p38-regulated activated kinase (PRAK)More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/30/2012
Entry Details Article
PubMed
TargetRho-associated protein kinase 2(Human)
Northwestern University

Curated by ChEMBL
LigandPNGBDBM14027(AT877 | CHEMBL38380 | 5-(1,4-diazepan-1-ylsulfonyl...)
Affinity DataIC50: 1.90E+3nMAssay Description:Inhibition of Protein kinase ROCK2 (ROCKII)More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/30/2012
Entry Details Article
PubMedPDB3D3D Structure (crystal)
TargetMyosin light chain kinase, smooth muscle(Human)
Northwestern University

Curated by ChEMBL
LigandPNGBDBM15234(NSC221019 | Wortmannin, Wm | cid_312145 | CHEMBL42...)
Affinity DataIC50: 1.90E+3nMAssay Description:Inhibition of Smooth muscle myosin light chain kinase (mMLCK)More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/30/2012
Entry Details Article
PubMed
TargetProstaglandin G/H synthase 1(Human)
Northwestern University

Curated by ChEMBL
LigandPNGBDBM13336(4-{4-(4-fluorophenyl)-2-[4-(methylsulfinyl)phenyl]...)
Affinity DataIC50: 2.00E+3nMAssay Description:Inhibitory activity against Prostaglandin G/H synthase 1 (COX-1)More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/30/2012
Entry Details Article
PubMed
TargetDual specificity mitogen-activated protein kinase kinase 1(Human)
Northwestern University

Curated by ChEMBL
LigandPNGBDBM50108771(2-(2-Amino-3-methoxy-phenyl)-chromen-4-one | PD-98...)
Affinity DataIC50: 2.00E+3nMAssay Description:Inhibition of Mitogen activated protein kinase kinase 1 (MKK1)More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/30/2012
Entry Details Article
PubMed
TargetCyclin-dependent kinase 2(Human)
Northwestern University

Curated by ChEMBL
LigandPNGBDBM50023867(Indirubin)
Affinity DataIC50: 2.20E+3nMAssay Description:Inhibition of Cyclin-dependent kinase 2 (CDK2)More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/30/2012
Entry Details Article
PubMed
LigandPNGBDBM2581(CHEMBL16958 | 3,13,23-triazahexacyclo[14.7.0.0^{2,...)
Affinity DataIC50: 2.45E+3nMAssay Description:Inhibition of Protein kinase CMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/30/2012
Entry Details Article
PubMed
TargetProtein kinase C delta type(Human)
Northwestern University

Curated by ChEMBL
LigandPNGBDBM50126829((E)-1-(6-(3-acetyl-2,4,6-trihydroxy-5-methylbenzyl...)
Affinity DataIC50: 3.00E+3nMAssay Description:Inhibition of Protein kinase C delta (PKCdelta)More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/30/2012
Entry Details Article
PubMed
TargetMitogen-activated protein kinase 11/12/13/14(Human)
Northwestern University

Curated by ChEMBL
LigandPNGBDBM50027095(SC-68376 | CHEMBL36450)
Affinity DataIC50: 5.00E+3nMAssay Description:Inhibition of Mitogen-activated protein kinase p38More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/30/2012
Entry Details Article
PubMed
TargetMalate dehydrogenase(Thermus thermophilus)
Northwestern University

Curated by ChEMBL
LigandPNGBDBM7460(2-(3,4-dihydroxyphenyl)-3,5,7-trihydroxy-chromone;...)
Affinity DataIC50: 6.00E+3nMAssay Description:Inhibitory activity against malate dehydrogenase (MDH) from Thermus flavusMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/30/2012
Entry Details Article
PubMed
TargetMalate dehydrogenase(Thermus thermophilus)
Northwestern University

Curated by ChEMBL
LigandPNGBDBM2581(CHEMBL16958 | 3,13,23-triazahexacyclo[14.7.0.0^{2,...)
Affinity DataIC50: 8.00E+3nMAssay Description:Inhibitory activity against malate dehydrogenase (MDH) from Thermus flavusMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/30/2012
Entry Details Article
PubMed
TargetChymotrypsinogen B(Human)
Northwestern University

Curated by ChEMBL
LigandPNGBDBM2581(CHEMBL16958 | 3,13,23-triazahexacyclo[14.7.0.0^{2,...)
Affinity DataIC50: 1.00E+4nMAssay Description:Inhibitory activity against Chymotrypsinogen from Thermus flavusMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/30/2012
Entry Details Article
PubMed
TargetChymotrypsinogen B(Human)
Northwestern University

Curated by ChEMBL
LigandPNGBDBM50111589(2-[(3,5-diiodo-4-oxidophenyl)(3,5-diiodo-4-oxocycl...)
Affinity DataIC50: 1.10E+4nMAssay Description:Inhibitory activity against Chymotrypsinogen from Thermus flavusMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/30/2012
Entry Details Article
PubMed
TargetDual specificity mitogen-activated protein kinase kinase 1(Human)
Northwestern University

Curated by ChEMBL
LigandPNGBDBM50072147(CHEMBL100473 | 2,3-Bis-[1-amino-1-(2-amino-phenyls...)
Affinity DataIC50: 1.30E+4nMAssay Description:Inhibition of Mitogen activated protein kinase kinase 1 (MKK1)More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/30/2012
Entry Details Article
PubMed
TargetChymotrypsinogen B(Human)
Northwestern University

Curated by ChEMBL
LigandPNGBDBM50111604(3-[1-(4-Phenoxy-phenylamino)-meth-(Z)-ylidene]-3H-...)
Affinity DataIC50: 1.50E+4nMAssay Description:Inhibitory activity against Chymotrypsinogen from Thermus flavusMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/30/2012
Entry Details Article
PubMed
TargetProto-oncogene tyrosine-protein kinase Src(Human)
Northwestern University

Curated by ChEMBL
LigandPNGBDBM50023867(Indirubin)
Affinity DataIC50: 1.80E+4nMAssay Description:Inhibition of Src tyrosine kinaseMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/30/2012
Entry Details Article
PubMed
TargetChymotrypsinogen B(Human)
Northwestern University

Curated by ChEMBL
LigandPNGBDBM3175(Bisindolylmaleimide 11b | Ro 31-8220 | CHEMBL6291 ...)
Affinity DataIC50: 2.00E+4nMAssay Description:Inhibitory activity against Chymotrypsinogen from Thermus flavusMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/30/2012
Entry Details Article
PubMed
TargetChymotrypsinogen B(Human)
Northwestern University

Curated by ChEMBL
LigandPNGBDBM50126829((E)-1-(6-(3-acetyl-2,4,6-trihydroxy-5-methylbenzyl...)
Affinity DataIC50: 2.50E+4nMAssay Description:Inhibitory activity against Chymotrypsinogen from Thermus flavusMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/30/2012
Entry Details Article
PubMed
TargetMalate dehydrogenase(Thermus thermophilus)
Northwestern University

Curated by ChEMBL
LigandPNGBDBM50111591(4-[2-(2,4-Difluoro-phenylamino)-thiazol-4-yl]-benz...)
Affinity DataIC50: 2.50E+4nMAssay Description:Inhibitory activity against malate dehydrogenase (MDH) from Thermus flavusMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/30/2012
Entry Details Article
PubMed
TargetMalate dehydrogenase(Thermus thermophilus)
Northwestern University

Curated by ChEMBL
LigandPNGBDBM50111589(2-[(3,5-diiodo-4-oxidophenyl)(3,5-diiodo-4-oxocycl...)
Affinity DataIC50: 2.50E+4nMAssay Description:Inhibitory activity against malate dehydrogenase (MDH) from Thermus flavusMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/30/2012
Entry Details Article
PubMed
TargetChymotrypsinogen B(Human)
Northwestern University

Curated by ChEMBL
LigandPNGBDBM50111585(4-bromophenylazophenol | 4-(4-Bromo-phenylazo)-phe...)
Affinity DataIC50: 2.50E+4nMAssay Description:Inhibitory activity against Chymotrypsinogen from Thermus flavusMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/30/2012
Entry Details Article
PubMed
TargetcAMP-dependent protein kinase catalytic subunit alpha/beta/gamma(Human)
Northwestern University

Curated by ChEMBL
LigandPNGBDBM2581(CHEMBL16958 | 3,13,23-triazahexacyclo[14.7.0.0^{2,...)
Affinity DataIC50: 2.57E+4nMAssay Description:Inhibition of Protein kinase AMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/30/2012
Entry Details Article
PubMed
TargetProto-oncogene tyrosine-protein kinase Src(Human)
Northwestern University

Curated by ChEMBL
LigandPNGBDBM50310357(indigo | CHEMBL599552)
Affinity DataIC50: 2.80E+4nMAssay Description:Inhibition of Src tyrosine kinaseMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/30/2012
Entry Details Article
PubMed
LigandPNGBDBM50336799(Suramin hexasodium | Germanin | suramin | 8,8'-[Ca...)
Affinity DataIC50: 2.90E+4nMAssay Description:Inhibition of Protein kinase C (PKC)More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/30/2012
Entry Details Article
PubMed
TargetMalate dehydrogenase(Thermus thermophilus)
Northwestern University

Curated by ChEMBL
LigandPNGBDBM50023867(Indirubin)
Affinity DataIC50: 3.00E+4nMAssay Description:Inhibitory activity against malate dehydrogenase (MDH) from Thermus flavusMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/30/2012
Entry Details Article
PubMed
TargetMalate dehydrogenase(Thermus thermophilus)
Northwestern University

Curated by ChEMBL
LigandPNGBDBM50111585(4-bromophenylazophenol | 4-(4-Bromo-phenylazo)-phe...)
Affinity DataIC50: 3.00E+4nMAssay Description:Inhibitory activity against malate dehydrogenase (MDH) from Thermus flavusMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/30/2012
Entry Details Article
PubMed
TargetMalate dehydrogenase(Thermus thermophilus)
Northwestern University

Curated by ChEMBL
LigandPNGBDBM3175(Bisindolylmaleimide 11b | Ro 31-8220 | CHEMBL6291 ...)
Affinity DataIC50: 4.50E+4nMAssay Description:Inhibitory activity against malate dehydrogenase (MDH) from Thermus flavusMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/30/2012
Entry Details Article
PubMed
TargetMAP kinase-activated protein kinase 5(Human)
Northwestern University

Curated by ChEMBL
LigandPNGBDBM50072147(CHEMBL100473 | 2,3-Bis-[1-amino-1-(2-amino-phenyls...)
Affinity DataIC50: 5.00E+4nMAssay Description:Inhibition of p38-regulated activated kinase (Protein kinase PRAK)More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/30/2012
Entry Details Article
PubMed
TargetMalate dehydrogenase(Thermus thermophilus)
Northwestern University

Curated by ChEMBL
LigandPNGBDBM50126827(4-(1-Hydroxy-naphthalen-2-ylazo)-naphthalene-1-sul...)
Affinity DataIC50: 5.00E+4nMAssay Description:Inhibitory activity against malate dehydrogenase (MDH) from Thermus flavusMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/30/2012
Entry Details Article
PubMed
TargetMalate dehydrogenase(Thermus thermophilus)
Northwestern University

Curated by ChEMBL
LigandPNGBDBM50310357(indigo | CHEMBL599552)
Affinity DataIC50: 6.00E+4nMAssay Description:Inhibitory activity against malate dehydrogenase (MDH) from Thermus flavusMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/30/2012
Entry Details Article
PubMed
TargetCyclin-dependent kinase 2(Human)
Northwestern University

Curated by ChEMBL
LigandPNGBDBM50310357(indigo | CHEMBL599552)
Affinity DataIC50: 7.00E+4nMAssay Description:Inhibition of Cyclin-dependent kinase 2 (CDK2)More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/30/2012
Entry Details Article
PubMed
TargetChymotrypsinogen B(Human)
Northwestern University

Curated by ChEMBL
LigandPNGBDBM50126827(4-(1-Hydroxy-naphthalen-2-ylazo)-naphthalene-1-sul...)
Affinity DataIC50: 9.00E+4nMAssay Description:Inhibitory activity against Chymotrypsinogen from Thermus flavusMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/30/2012
Entry Details Article
PubMed
TargetChymotrypsinogen B(Human)
Northwestern University

Curated by ChEMBL
LigandPNGBDBM50310357(indigo | CHEMBL599552)
Affinity DataIC50: 9.00E+4nMAssay Description:Inhibitory activity against Chymotrypsinogen from Thermus flavusMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/30/2012
Entry Details Article
PubMed
TargetChymotrypsinogen B(Human)
Northwestern University

Curated by ChEMBL
LigandPNGBDBM50111591(4-[2-(2,4-Difluoro-phenylamino)-thiazol-4-yl]-benz...)
Affinity DataIC50: 1.00E+5nMAssay Description:Inhibitory activity against Chymotrypsinogen from Thermus flavusMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/30/2012
Entry Details Article
PubMed
TargetChymotrypsinogen B(Human)
Northwestern University

Curated by ChEMBL
LigandPNGBDBM7460(2-(3,4-dihydroxyphenyl)-3,5,7-trihydroxy-chromone;...)
Affinity DataIC50: 1.00E+5nMAssay Description:Inhibitory activity against Chymotrypsinogen from Thermus flavusMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/30/2012
Entry Details Article
PubMed
TargetChymotrypsinogen B(Human)
Northwestern University

Curated by ChEMBL
LigandPNGBDBM50023867(Indirubin)
Affinity DataIC50: 1.00E+5nMAssay Description:Inhibitory activity against Chymotrypsinogen from Thermus flavusMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/30/2012
Entry Details Article
PubMed
TargetMalate dehydrogenase(Thermus thermophilus)
Northwestern University

Curated by ChEMBL
LigandPNGBDBM50072147(CHEMBL100473 | 2,3-Bis-[1-amino-1-(2-amino-phenyls...)
Affinity DataIC50: 1.00E+5nMAssay Description:Inhibitory activity against malate dehydrogenase (MDH) from Thermus flavusMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/30/2012
Entry Details Article
PubMed
TargetChymotrypsinogen B(Human)
Northwestern University

Curated by ChEMBL
LigandPNGBDBM50072147(CHEMBL100473 | 2,3-Bis-[1-amino-1-(2-amino-phenyls...)
Affinity DataIC50: 1.20E+5nMAssay Description:Inhibitory activity against Chymotrypsinogen from Thermus flavusMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/30/2012
Entry Details Article
PubMed
TargetMalate dehydrogenase(Thermus thermophilus)
Northwestern University

Curated by ChEMBL
LigandPNGBDBM50111604(3-[1-(4-Phenoxy-phenylamino)-meth-(Z)-ylidene]-3H-...)
Affinity DataIC50: 1.20E+5nMAssay Description:Inhibitory activity against malate dehydrogenase (MDH) from Thermus flavusMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/30/2012
Entry Details Article
PubMed
TargetChymotrypsinogen B(Human)
Northwestern University

Curated by ChEMBL
LigandPNGBDBM2681(3-{1-[3-(dimethylamino)propyl]-1H-indol-3-yl}-4-(1...)
Affinity DataIC50: 2.00E+5nMAssay Description:Inhibitory activity against Chymotrypsinogen from Thermus flavusMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/30/2012
Entry Details Article
PubMed
TargetMalate dehydrogenase(Thermus thermophilus)
Northwestern University

Curated by ChEMBL
LigandPNGBDBM2681(3-{1-[3-(dimethylamino)propyl]-1H-indol-3-yl}-4-(1...)
Affinity DataIC50: 4.00E+5nMAssay Description:Inhibitory activity against malate dehydrogenase (MDH) from Thermus flavusMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/30/2012
Entry Details Article
PubMed