Compile Data Set for Download or QSAR
Report error Found 17 Enz. Inhib. hit(s) with all data for entry = 50013087
TargetMelanocortin receptor 4(Human)
University of California

Curated by ChEMBL
LigandPNGBDBM50126395([Nle4]-alpha-Melanocyte Stimulating Hormone | Ac-S...)
Affinity DataIC50: 15nMAssay Description:Binding affinity against human melanocortin 4 receptor (hMC4R) using [125I]- agouti related protein (AGRP) as radioligandMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetMelanocortin receptor 4(Human)
University of California

Curated by ChEMBL
LigandPNGBDBM50126395([Nle4]-alpha-Melanocyte Stimulating Hormone | Ac-S...)
Affinity DataIC50: 16nMAssay Description:Binding affinity against human melanocortin 4 receptor (hMC4R) using [125I]- ([Nle4]alpha-MSH) as radioligandMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetMelanocortin receptor 4(Human)
University of California

Curated by ChEMBL
LigandPNGBDBM50126395([Nle4]-alpha-Melanocyte Stimulating Hormone | Ac-S...)
Affinity DataIC50: 19nMAssay Description:Binding affinity against human melanocortin 4 receptor (hMC4R) using [125I]- NDP-MSH as radioligandMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetMelanocortin receptor 4(Human)
University of California

Curated by ChEMBL
LigandPNGBDBM50126393(N-Benzhydryl-N-{[carbamoylmethyl-((R)-1-phenyl-eth...)
Affinity DataIC50: 1.90E+3nMAssay Description:Inhibitory activity against hMC4R (human melanocortin receptor) using I-AGRP as radioligandMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetMelanocortin receptor 4(Human)
University of California

Curated by ChEMBL
LigandPNGBDBM50126393(N-Benzhydryl-N-{[carbamoylmethyl-((R)-1-phenyl-eth...)
Affinity DataIC50: 1.90E+3nMAssay Description:Inhibitory activity against hMC4R (human melanocortin receptor) using [125I]-[Nle4] alpha-MSH as radioligandMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetMelanocortin receptor 4(Human)
University of California

Curated by ChEMBL
LigandPNGBDBM50126393(N-Benzhydryl-N-{[carbamoylmethyl-((R)-1-phenyl-eth...)
Affinity DataIC50: 2.10E+3nMAssay Description:Binding affinity against human melanocortin 4 receptor (hMC4R) using [125I]- NDP-MSH as radioligandMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetMelanocortin receptor 4(Human)
University of California

Curated by ChEMBL
LigandPNGBDBM50126393(N-Benzhydryl-N-{[carbamoylmethyl-((R)-1-phenyl-eth...)
Affinity DataIC50: 3.10E+3nMAssay Description:Binding affinity against human melanocortin 4 receptor (hMC4R) using [125I]- ([Nle4]alpha-MSH) as radioligandMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetMelanocortin receptor 4(Human)
University of California

Curated by ChEMBL
LigandPNGBDBM50126393(N-Benzhydryl-N-{[carbamoylmethyl-((R)-1-phenyl-eth...)
Affinity DataIC50: 3.10E+3nMAssay Description:Inhibitory activity against hMC4R (human melanocortin receptor) using [125I]-[Nle4] alpha-MSH as radioligandMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetMelanocyte-stimulating hormone receptor(Human)
University of California

Curated by ChEMBL
LigandPNGBDBM50126393(N-Benzhydryl-N-{[carbamoylmethyl-((R)-1-phenyl-eth...)
Affinity DataIC50: 9.10E+3nMAssay Description:Inhibitory activity against hMC1R (human melanocortin receptor) using [125I]-[Nle4] alpha-MSH as radioligandMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetMelanocyte-stimulating hormone receptor(Human)
University of California

Curated by ChEMBL
LigandPNGBDBM50126393(N-Benzhydryl-N-{[carbamoylmethyl-((R)-1-phenyl-eth...)
Affinity DataIC50: 2.50E+4nMAssay Description:Inhibitory activity against hMC1R (human melanocortin receptor) using [125I]- ASIP Y radioligandMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetMelanocortin receptor 3(Human)
University of California

Curated by ChEMBL
LigandPNGBDBM50126393(N-Benzhydryl-N-{[carbamoylmethyl-((R)-1-phenyl-eth...)
Affinity DataIC50: 4.80E+4nMAssay Description:Inhibitory activity against hMC3R (human melanocortin receptor) using [125I]-[Nle4] alpha-MSH as radioligandMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetMelanocortin receptor 3(Human)
University of California

Curated by ChEMBL
LigandPNGBDBM50126393(N-Benzhydryl-N-{[carbamoylmethyl-((R)-1-phenyl-eth...)
Affinity DataIC50: 5.00E+4nMAssay Description:Inhibitory activity against hMC3R (human melanocortin receptor) using I-AGRP as radioligandMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetMelanocortin receptor 4(Human)
University of California

Curated by ChEMBL
LigandPNGBDBM50126396(N-Benzyl-N-{[carbamoylmethyl-((R)-1-phenyl-ethyl)-...)
Affinity DataIC50: 1.00E+5nMAssay Description:Inhibitory activity against hMC4R (human melanocortin receptor) using [125I]-[Nle4] alpha-MSH as radioligandMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetMelanocortin receptor 4(Human)
University of California

Curated by ChEMBL
LigandPNGBDBM50126397(2-[Benzyl-(2-{[2-(3-guanidino-propylamino)-acetyl]...)
Affinity DataIC50: 1.00E+5nMAssay Description:Binding affinity against human melanocortin 4 receptor (hMC4R) using [125I]- ([Nle4]alpha-MSH) as radioligandMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetMelanocortin receptor 4(Human)
University of California

Curated by ChEMBL
LigandPNGBDBM50126394(N-Benzyl-N-[(benzyl-carbamoylmethyl-carbamoyl)-met...)
Affinity DataIC50: 1.00E+5nMAssay Description:Inhibitory activity against hMC4R (human melanocortin receptor) using [125I]-[Nle4] alpha-MSH as radioligandMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetMelanocortin receptor 4(Human)
University of California

Curated by ChEMBL
LigandPNGBDBM50126396(N-Benzyl-N-{[carbamoylmethyl-((R)-1-phenyl-ethyl)-...)
Affinity DataIC50: 1.00E+5nMAssay Description:Binding affinity against human melanocortin 4 receptor (hMC4R) using [125I]- ([Nle4]alpha-MSH) as radioligandMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetMelanocortin receptor 4(Human)
University of California

Curated by ChEMBL
LigandPNGBDBM50126394(N-Benzyl-N-[(benzyl-carbamoylmethyl-carbamoyl)-met...)
Affinity DataIC50: 1.00E+5nMAssay Description:Binding affinity against human melanocortin 4 receptor (hMC4R) using [125I]- ([Nle4]alpha-MSH) as radioligandMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed