Compile Data Set for Download or QSAR
Report error Found 28 Enz. Inhib. hit(s) with all data for entry = 50012903
TargetProthrombin(Human)
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50067797(N-(6-Amino-2-methyl-pyridin-3-ylmethyl)-2-(6-methy...)
Affinity DataKi:  0.800nMAssay Description:Inhibition of ThrombinMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetProthrombin(Human)
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50124086(2-[6-Methyl-2-oxo-3-(2-pyridin-2-yl-ethylamino)-2H...)
Affinity DataKi:  1.20nMAssay Description:Inhibition of ThrombinMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetProthrombin(Human)
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50124093(N-(1H-Indol-5-ylmethyl)-2-[6-methyl-2-oxo-3-(2-pyr...)
Affinity DataKi:  1.60nMAssay Description:Inhibition of ThrombinMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetProthrombin(Human)
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50124091(2-[6-Methyl-2-oxo-3-(2-pyridin-2-yl-ethylamino)-2H...)
Affinity DataKi:  3.20nMAssay Description:Inhibition of ThrombinMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetProthrombin(Human)
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50124092(2-(6-Methyl-2-oxo-3-phenethylamino-2H-pyrazin-1-yl...)
Affinity DataKi:  3.70nMAssay Description:Inhibition of ThrombinMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetProthrombin(Human)
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50124090(2-[6-Methyl-2-oxo-3-(2-pyridin-2-yl-ethylamino)-2H...)
Affinity DataKi:  6.60nMAssay Description:Inhibition of ThrombinMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetProthrombin(Human)
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50124087(N-(1H-Benzoimidazol-5-ylmethyl)-2-(6-methyl-2-oxo-...)
Affinity DataKi:  11nMAssay Description:Inhibition of ThrombinMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetProthrombin(Human)
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50124088(N-(5-Methyl-imidazo[1,2-a]pyridin-6-ylmethyl)-2-(6...)
Affinity DataKi:  11nMAssay Description:Inhibition of ThrombinMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetProthrombin(Human)
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50124089(2-(6-Methyl-2-oxo-3-phenethylamino-2H-pyrazin-1-yl...)
Affinity DataKi:  11nMAssay Description:Inhibition of ThrombinMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetProthrombin(Human)
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50124095(2-(6-Methyl-2-oxo-3-phenethylamino-2H-pyrazin-1-yl...)
Affinity DataKi:  18nMAssay Description:Inhibition of ThrombinMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetProthrombin(Human)
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50124097(N-(1H-Indol-5-ylmethyl)-2-(6-methyl-2-oxo-3-phenet...)
Affinity DataKi:  18nMAssay Description:Inhibition of ThrombinMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetProthrombin(Human)
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50124098(N-Imidazo[1,2-a]pyridin-6-ylmethyl-2-(6-methyl-2-o...)
Affinity DataKi:  140nMAssay Description:Inhibition of ThrombinMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetProthrombin(Human)
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50124096(N-Imidazo[1,2-a]pyridin-7-ylmethyl-2-(6-methyl-2-o...)
Affinity DataKi:  270nMAssay Description:Inhibition of ThrombinMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetProthrombin(Human)
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50124094(N-(1H-Indol-6-ylmethyl)-2-(6-methyl-2-oxo-3-phenet...)
Affinity DataKi:  830nMAssay Description:Inhibition of ThrombinMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetSerine protease 1(Human)
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50067797(N-(6-Amino-2-methyl-pyridin-3-ylmethyl)-2-(6-methy...)
Affinity DataKi:  1.80E+3nMAssay Description:Inhibition of TrypsinMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetSerine protease 1(Human)
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50124087(N-(1H-Benzoimidazol-5-ylmethyl)-2-(6-methyl-2-oxo-...)
Affinity DataKi:  2.00E+3nMAssay Description:Inhibition of TrypsinMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetSerine protease 1(Human)
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50124088(N-(5-Methyl-imidazo[1,2-a]pyridin-6-ylmethyl)-2-(6...)
Affinity DataKi:  6.80E+3nMAssay Description:Inhibition of TrypsinMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetSerine protease 1(Human)
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50124098(N-Imidazo[1,2-a]pyridin-6-ylmethyl-2-(6-methyl-2-o...)
Affinity DataKi:  1.00E+5nMAssay Description:Inhibition of TrypsinMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetSerine protease 1(Human)
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50124097(N-(1H-Indol-5-ylmethyl)-2-(6-methyl-2-oxo-3-phenet...)
Affinity DataKi: >1.00E+5nMAssay Description:Inhibition of TrypsinMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetSerine protease 1(Human)
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50124095(2-(6-Methyl-2-oxo-3-phenethylamino-2H-pyrazin-1-yl...)
Affinity DataKi: >1.00E+5nMAssay Description:Inhibition of TrypsinMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetSerine protease 1(Human)
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50124092(2-(6-Methyl-2-oxo-3-phenethylamino-2H-pyrazin-1-yl...)
Affinity DataKi: >1.00E+5nMAssay Description:Inhibition of TrypsinMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetSerine protease 1(Human)
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50124094(N-(1H-Indol-6-ylmethyl)-2-(6-methyl-2-oxo-3-phenet...)
Affinity DataKi: >1.00E+5nMAssay Description:Inhibition of TrypsinMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetSerine protease 1(Human)
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50124089(2-(6-Methyl-2-oxo-3-phenethylamino-2H-pyrazin-1-yl...)
Affinity DataKi: >1.00E+5nMAssay Description:Inhibition of TrypsinMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetSerine protease 1(Human)
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50124096(N-Imidazo[1,2-a]pyridin-7-ylmethyl-2-(6-methyl-2-o...)
Affinity DataKi:  1.20E+5nMAssay Description:Inhibition of TrypsinMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetSerine protease 1(Human)
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50124090(2-[6-Methyl-2-oxo-3-(2-pyridin-2-yl-ethylamino)-2H...)
Affinity DataKi:  1.40E+5nMAssay Description:Inhibition of TrypsinMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetSerine protease 1(Human)
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50124086(2-[6-Methyl-2-oxo-3-(2-pyridin-2-yl-ethylamino)-2H...)
Affinity DataKi:  2.00E+5nMAssay Description:Inhibition of TrypsinMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetSerine protease 1(Human)
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50124093(N-(1H-Indol-5-ylmethyl)-2-[6-methyl-2-oxo-3-(2-pyr...)
Affinity DataKi:  2.90E+5nMAssay Description:Inhibition of TrypsinMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetSerine protease 1(Human)
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50124091(2-[6-Methyl-2-oxo-3-(2-pyridin-2-yl-ethylamino)-2H...)
Affinity DataKi: >1.00E+6nMAssay Description:Inhibition of TrypsinMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed