Compile Data Set for Download or QSAR
Report error Found 30 Enz. Inhib. hit(s) with all data for entry = 50012765
TargetMelanocortin receptor 4(Human)
Amgen

Curated by ChEMBL
LigandPNGBDBM50122512(3-{4-[2-(4-Fluoro-phenyl)-2-(4-methyl-piperazin-1-...)
Affinity DataIC50: 52nMAssay Description:In vitro ability to inhibit the binding of [125I]AGRP to the human Melanocortin 4 receptorMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetMelanocortin receptor 4(Human)
Amgen

Curated by ChEMBL
LigandPNGBDBM50122513(1-(4-Chloro-phenyl)-3-{4-[2-(4-chloro-phenyl)-2-(4...)
Affinity DataIC50: 118nMAssay Description:In vitro ability to inhibit the binding of [125I]AGRP to the human Melanocortin 4 receptorMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetMelanocortin receptor 4(Human)
Amgen

Curated by ChEMBL
LigandPNGBDBM50122513(1-(4-Chloro-phenyl)-3-{4-[2-(4-chloro-phenyl)-2-(4...)
Affinity DataIC50: 150nMAssay Description:In vitro ability to inhibit the binding of alpha [125I]NDP-MSH to the human Melanocortin 4 receptorMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetMelanocortin receptor 4(Human)
Amgen

Curated by ChEMBL
LigandPNGBDBM50122508(3-{4-[2-(4-Cyclohexyl-piperazin-1-yl)-2-(4-fluoro-...)
Affinity DataIC50: 152nMAssay Description:In vitro ability to inhibit the binding of [125I]AGRP to the human Melanocortin 4 receptorMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetMelanocortin receptor 4(Human)
Amgen

Curated by ChEMBL
LigandPNGBDBM50122508(3-{4-[2-(4-Cyclohexyl-piperazin-1-yl)-2-(4-fluoro-...)
Affinity DataIC50: 164nMAssay Description:In vitro ability to inhibit the binding of alpha [125I]NDP-MSH to the human Melanocortin 4 receptorMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetMelanocortin receptor 4(Human)
Amgen

Curated by ChEMBL
LigandPNGBDBM50122515(1-(4-Chloro-phenyl)-3-{4-[2-(4-fluoro-phenyl)-2-(4...)
Affinity DataIC50: 178nMAssay Description:In vitro ability to inhibit the binding of alpha [125I]NDP-MSH to the human Melanocortin 4 receptorMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetMelanocortin receptor 4(Human)
Amgen

Curated by ChEMBL
LigandPNGBDBM50122516(1-(3,4-Dichloro-phenyl)-3-{4-[2-(4-fluoro-phenyl)-...)
Affinity DataIC50: 188nMAssay Description:In vitro ability to inhibit the binding of alpha [125I]NDP-MSH to the human Melanocortin 4 receptorMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetMelanocortin receptor 4(Human)
Amgen

Curated by ChEMBL
LigandPNGBDBM50122502(3-{4-[2-(4-Ethyl-piperazin-1-yl)-2-(4-fluoro-pheny...)
Affinity DataIC50: 193nMAssay Description:In vitro ability to inhibit the binding of alpha [125I]NDP-MSH to the human Melanocortin 4 receptorMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetMelanocortin receptor 4(Human)
Amgen

Curated by ChEMBL
LigandPNGBDBM50122512(3-{4-[2-(4-Fluoro-phenyl)-2-(4-methyl-piperazin-1-...)
Affinity DataIC50: 217nMAssay Description:In vitro ability to inhibit the binding of alpha [125I]NDP-MSH to the human Melanocortin 4 receptorMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetMelanocortin receptor 4(Human)
Amgen

Curated by ChEMBL
LigandPNGBDBM50122507(3-{4-[2-(4-Fluoro-phenyl)-2-(4-phenyl-piperazin-1-...)
Affinity DataIC50: 249nMAssay Description:In vitro ability to inhibit the binding of alpha [125I]NDP-MSH to the human Melanocortin 4 receptorMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetMelanocortin receptor 4(Human)
Amgen

Curated by ChEMBL
LigandPNGBDBM50122515(1-(4-Chloro-phenyl)-3-{4-[2-(4-fluoro-phenyl)-2-(4...)
Affinity DataIC50: 266nMAssay Description:In vitro ability to inhibit the binding of [125I]AGRP to the human Melanocortin 4 receptorMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetMelanocortin receptor 4(Human)
Amgen

Curated by ChEMBL
LigandPNGBDBM50122502(3-{4-[2-(4-Ethyl-piperazin-1-yl)-2-(4-fluoro-pheny...)
Affinity DataIC50: 321nMAssay Description:In vitro ability to inhibit the binding of [125I]AGRP to the human Melanocortin 4 receptorMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetMelanocortin receptor 4(Human)
Amgen

Curated by ChEMBL
LigandPNGBDBM50122510(3-{4-[2-(3-Chloro-phenyl)-2-(4-methyl-piperazin-1-...)
Affinity DataIC50: 336nMAssay Description:In vitro ability to inhibit the binding of [125I]AGRP to the human Melanocortin 4 receptorMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetMelanocortin receptor 4(Human)
Amgen

Curated by ChEMBL
LigandPNGBDBM50122516(1-(3,4-Dichloro-phenyl)-3-{4-[2-(4-fluoro-phenyl)-...)
Affinity DataIC50: 364nMAssay Description:In vitro ability to inhibit the binding of [125I]AGRP to the human Melanocortin 4 receptorMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetMelanocortin receptor 4(Human)
Amgen

Curated by ChEMBL
LigandPNGBDBM50122509(3-{4-[2-(4-Fluoro-phenyl)-2-(4-methyl-piperazin-1-...)
Affinity DataIC50: 469nMAssay Description:In vitro ability to inhibit the binding of alpha [125I]NDP-MSH to the human Melanocortin 4 receptorMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetMelanocortin receptor 4(Human)
Amgen

Curated by ChEMBL
LigandPNGBDBM50122505(3-{4-[2-(4-Fluoro-phenyl)-2-(4-methyl-piperazin-1-...)
Affinity DataIC50: 588nMAssay Description:In vitro ability to inhibit the binding of [125I]AGRP to the human Melanocortin 4 receptorMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetMelanocortin receptor 4(Human)
Amgen

Curated by ChEMBL
LigandPNGBDBM50122506(3-{4-[2-(4-Fluoro-phenyl)-2-(4-methyl-piperazin-1-...)
Affinity DataIC50: 597nMAssay Description:In vitro ability to inhibit the binding of alpha [125I]NDP-MSH to the human Melanocortin 4 receptorMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetMelanocortin receptor 4(Human)
Amgen

Curated by ChEMBL
LigandPNGBDBM50122510(3-{4-[2-(3-Chloro-phenyl)-2-(4-methyl-piperazin-1-...)
Affinity DataIC50: 598nMAssay Description:In vitro ability to inhibit the binding of alpha [125I]NDP-MSH to the human Melanocortin 4 receptorMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetMelanocortin receptor 4(Human)
Amgen

Curated by ChEMBL
LigandPNGBDBM50122509(3-{4-[2-(4-Fluoro-phenyl)-2-(4-methyl-piperazin-1-...)
Affinity DataIC50: 820nMAssay Description:In vitro ability to inhibit the binding of [125I]AGRP to the human Melanocortin 4 receptorMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetMelanocortin receptor 4(Human)
Amgen

Curated by ChEMBL
LigandPNGBDBM50122505(3-{4-[2-(4-Fluoro-phenyl)-2-(4-methyl-piperazin-1-...)
Affinity DataIC50: 1.50E+3nMAssay Description:In vitro ability to inhibit the binding of alpha [125I]NDP-MSH to the human Melanocortin 4 receptorMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetMelanocortin receptor 4(Human)
Amgen

Curated by ChEMBL
LigandPNGBDBM50122506(3-{4-[2-(4-Fluoro-phenyl)-2-(4-methyl-piperazin-1-...)
Affinity DataIC50: 2.15E+3nMAssay Description:In vitro ability to inhibit the binding of [125I]AGRP to the human Melanocortin 4 receptorMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetMelanocortin receptor 4(Human)
Amgen

Curated by ChEMBL
LigandPNGBDBM50122507(3-{4-[2-(4-Fluoro-phenyl)-2-(4-phenyl-piperazin-1-...)
Affinity DataIC50: 2.86E+3nMAssay Description:In vitro ability to inhibit the binding of [125I]AGRP to the human Melanocortin 4 receptorMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetMelanocortin receptor 4(Human)
Amgen

Curated by ChEMBL
LigandPNGBDBM50122511(2-{4-[2-(4-Chloro-phenyl)-2-(4-methyl-piperazin-1-...)
Affinity DataIC50: 3.23E+3nMAssay Description:In vitro ability to inhibit the binding of alpha [125I]NDP-MSH to the human Melanocortin 4 receptorMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetMelanocortin receptor 4(Human)
Amgen

Curated by ChEMBL
LigandPNGBDBM50122503(1-{1-(4-fluorophenyl)-2-[4-(3-phenylpropyl)hexahyd...)
Affinity DataIC50: 3.83E+3nMAssay Description:In vitro ability to inhibit the binding of alpha [125I]NDP-MSH to the human Melanocortin 4 receptorMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetMelanocortin receptor 4(Human)
Amgen

Curated by ChEMBL
LigandPNGBDBM50122514(2-Methyl-3-{4-[2-(4-methyl-piperazin-1-yl)-2-pheny...)
Affinity DataIC50: 5.00E+3nMAssay Description:In vitro ability to inhibit the binding of [125I]AGRP to the human Melanocortin 4 receptorMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetMelanocortin receptor 4(Human)
Amgen

Curated by ChEMBL
LigandPNGBDBM50122511(2-{4-[2-(4-Chloro-phenyl)-2-(4-methyl-piperazin-1-...)
Affinity DataIC50: 1.00E+4nMAssay Description:In vitro ability to inhibit the binding of [125I]AGRP to the human Melanocortin 4 receptorMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetMelanocortin receptor 4(Human)
Amgen

Curated by ChEMBL
LigandPNGBDBM50122514(2-Methyl-3-{4-[2-(4-methyl-piperazin-1-yl)-2-pheny...)
Affinity DataIC50: 1.00E+4nMAssay Description:In vitro ability to inhibit the binding of alpha [125I]NDP-MSH to the human Melanocortin 4 receptorMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetMelanocortin receptor 4(Human)
Amgen

Curated by ChEMBL
LigandPNGBDBM50122504(3-{4-[2-(4-Fluoro-phenyl)-2-(4-methyl-piperazin-1-...)
Affinity DataIC50: 1.00E+4nMAssay Description:In vitro ability to inhibit the binding of alpha [125I]NDP-MSH to the human Melanocortin 4 receptorMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetMelanocortin receptor 4(Human)
Amgen

Curated by ChEMBL
LigandPNGBDBM50122504(3-{4-[2-(4-Fluoro-phenyl)-2-(4-methyl-piperazin-1-...)
Affinity DataIC50: 1.00E+4nMAssay Description:In vitro ability to inhibit the binding of [125I]AGRP to the human Melanocortin 4 receptorMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetMelanocortin receptor 4(Human)
Amgen

Curated by ChEMBL
LigandPNGBDBM50122503(1-{1-(4-fluorophenyl)-2-[4-(3-phenylpropyl)hexahyd...)
Affinity DataIC50: 1.00E+4nMAssay Description:In vitro ability to inhibit the binding of [125I]AGRP to the human Melanocortin 4 receptorMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed