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Found
10
Enz. Inhib. hit(s) with all data for entry = 50022499
Target
Epidermal growth factor receptor
(Human)
AstraZeneca
Curated by
ChEMBL
Ligand
BDBM5447
(ZD1839 | N-(3-chloro-4-fluorophenyl)-7-methoxy-6-[...)
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Affinity Data
IC50: 27nM
More data for this Ligand-Target Pair
Target Info
PDB
KEGG
UniProtKB/SwissProt
GoogleScholar
Ligand Info
Purchase
ChEBI
CHEMBL
DrugBank
PC cid
PC sid
PDB
Similars
In Depth
Date in BDB:
10/13/2025
Entry Details
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PubMed
PDB
3D Structure (crystal)
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Target
Epidermal growth factor receptor
(Human)
AstraZeneca
Curated by
ChEMBL
Ligand
BDBM5447
(ZD1839 | N-(3-chloro-4-fluorophenyl)-7-methoxy-6-[...)
Copy SMILES
Copy InChI
Affinity Data
IC50: 33nM
More data for this Ligand-Target Pair
Target Info
PDB
KEGG
UniProtKB/SwissProt
GoogleScholar
Ligand Info
Purchase
ChEBI
CHEMBL
DrugBank
PC cid
PC sid
PDB
Similars
In Depth
Date in BDB:
10/13/2025
Entry Details
Copy Entry DOI
PubMed
PDB
3D Structure (crystal)
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Target
Receptor tyrosine-protein kinase erbB-2
(Human)
AstraZeneca
Curated by
ChEMBL
Ligand
BDBM5447
(ZD1839 | N-(3-chloro-4-fluorophenyl)-7-methoxy-6-[...)
Copy SMILES
Copy InChI
Affinity Data
IC50: 3.70E+3nM
More data for this Ligand-Target Pair
Target Info
PDB
UniProtKB/SwissProt
GoogleScholar
Ligand Info
Purchase
ChEBI
CHEMBL
DrugBank
PC cid
PC sid
PDB
Similars
In Depth
Date in BDB:
10/13/2025
Entry Details
Copy Entry DOI
PubMed
Copy Rxn URL
Target
Vascular endothelial growth factor receptor 2
(Human)
AstraZeneca
Curated by
ChEMBL
Ligand
BDBM5447
(ZD1839 | N-(3-chloro-4-fluorophenyl)-7-methoxy-6-[...)
Copy SMILES
Copy InChI
Affinity Data
IC50: 3.70E+3nM
More data for this Ligand-Target Pair
Target Info
PDB
KEGG
UniProtKB/SwissProt
GoogleScholar
Ligand Info
Purchase
ChEBI
CHEMBL
DrugBank
PC cid
PC sid
PDB
Similars
In Depth
Date in BDB:
10/13/2025
Entry Details
Copy Entry DOI
PubMed
Copy Rxn URL
Target
RAF proto-oncogene serine/threonine-protein kinase
(Human)
AstraZeneca
Curated by
ChEMBL
Ligand
BDBM5447
(ZD1839 | N-(3-chloro-4-fluorophenyl)-7-methoxy-6-[...)
Copy SMILES
Copy InChI
Affinity Data
IC50: 1.00E+4nM
More data for this Ligand-Target Pair
Target Info
PDB
KEGG
UniProtKB/SwissProt
UniProtKB/TrEMBL
GoogleScholar
Ligand Info
Purchase
ChEBI
CHEMBL
DrugBank
PC cid
PC sid
PDB
Similars
In Depth
Date in BDB:
10/13/2025
Entry Details
Copy Entry DOI
PubMed
Copy Rxn URL
Target
Dual specificity mitogen-activated protein kinase kinase 1
(Human)
AstraZeneca
Curated by
ChEMBL
Ligand
BDBM5447
(ZD1839 | N-(3-chloro-4-fluorophenyl)-7-methoxy-6-[...)
Copy SMILES
Copy InChI
Affinity Data
IC50: 1.00E+4nM
More data for this Ligand-Target Pair
Target Info
PDB
KEGG
UniProtKB/SwissProt
GoogleScholar
Ligand Info
Purchase
ChEBI
CHEMBL
DrugBank
PC cid
PC sid
PDB
Similars
In Depth
Date in BDB:
10/13/2025
Entry Details
Copy Entry DOI
PubMed
Copy Rxn URL
Target
Vascular endothelial growth factor receptor 1
(Human)
AstraZeneca
Curated by
ChEMBL
Ligand
BDBM5447
(ZD1839 | N-(3-chloro-4-fluorophenyl)-7-methoxy-6-[...)
Copy SMILES
Copy InChI
Affinity Data
IC50: 1.00E+5nM
More data for this Ligand-Target Pair
Target Info
PDB
KEGG
UniProtKB/SwissProt
GoogleScholar
Ligand Info
Purchase
ChEBI
CHEMBL
DrugBank
PC cid
PC sid
PDB
Similars
In Depth
Date in BDB:
10/13/2025
Entry Details
Copy Entry DOI
PubMed
Copy Rxn URL
Target
Mitogen-activated protein kinase 1
(Human)
AstraZeneca
Curated by
ChEMBL
Ligand
BDBM5447
(ZD1839 | N-(3-chloro-4-fluorophenyl)-7-methoxy-6-[...)
Copy SMILES
Copy InChI
Affinity Data
IC50: 1.00E+5nM
More data for this Ligand-Target Pair
Target Info
PDB
KEGG
UniProtKB/SwissProt
GoogleScholar
Ligand Info
Purchase
ChEBI
CHEMBL
DrugBank
PC cid
PC sid
PDB
Similars
In Depth
Date in BDB:
10/13/2025
Entry Details
Copy Entry DOI
PubMed
Copy Rxn URL
Target
Epidermal growth factor receptor
(Human)
AstraZeneca
Curated by
ChEMBL
Ligand
BDBM5447
(ZD1839 | N-(3-chloro-4-fluorophenyl)-7-methoxy-6-[...)
Copy SMILES
Copy InChI
Affinity Data
Ki: 2.10nM
More data for this Ligand-Target Pair
Target Info
PDB
KEGG
UniProtKB/SwissProt
GoogleScholar
Ligand Info
Purchase
ChEBI
CHEMBL
DrugBank
PC cid
PC sid
PDB
Similars
In Depth
Date in BDB:
10/13/2025
Entry Details
Copy Entry DOI
PubMed
PDB
3D Structure (crystal)
Copy Rxn URL
Target
Epidermal growth factor receptor
(Human)
AstraZeneca
Curated by
ChEMBL
Ligand
BDBM5447
(ZD1839 | N-(3-chloro-4-fluorophenyl)-7-methoxy-6-[...)
Copy SMILES
Copy InChI
Affinity Data
Ki: 15nM
More data for this Ligand-Target Pair
Target Info
PDB
KEGG
UniProtKB/SwissProt
GoogleScholar
Ligand Info
Purchase
ChEBI
CHEMBL
DrugBank
PC cid
PC sid
PDB
Similars
In Depth
Date in BDB:
10/13/2025
Entry Details
Copy Entry DOI
PubMed
PDB
3D Structure (crystal)
Copy Rxn URL