Compile Data Set for Download or QSAR
Report error Found 41 Enz. Inhib. hit(s) with all data for entry = 50012514
TargetVasopressin V2 receptor(Human)
Johnson and Johnson Pharmaceutical Research and Development

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50119818BDBM50119818(3-chloro-4-[16-ethyl-2,10-diazatetracyclo[11.2.1.0...)
Affinity DataIC50: 4nMAssay Description:Inhibition of AVP mediated activation of human vasopressin V2 receptor expressed in HEK293 cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetVasopressin V2 receptor(Human)
Johnson and Johnson Pharmaceutical Research and Development

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50119815BDBM50119815(3-chloro-4-[16-methyl-(12S)-2,10-diazatetracyclo[1...)
Affinity DataIC50: 4nMAssay Description:Inhibition of AVP mediated activation of human vasopressin V2 receptor expressed in HEK293 cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetVasopressin V1a receptor(Human)
Johnson and Johnson Pharmaceutical Research and Development

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50119813BDBM50119813(1N-{4-[6-chloro-16-methyl-(12S)-2,10-diazatetracyc...)
Affinity DataIC50: 4nMAssay Description:Inhibition of [3H]Arg-vasopressin binding to recombinant human vasopressin V1a receptorMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetVasopressin V2 receptor(Human)
Johnson and Johnson Pharmaceutical Research and Development

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50119807BDBM50119807(1N-{4-[6-chloro-16-methyl-(12S)-2,10-diazatetracyc...)
Affinity DataIC50: 5nMAssay Description:Inhibition of [3H]Arg-vasopressin binding to recombinant human vasopressin V2 receptorMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetVasopressin V1a receptor(Human)
Johnson and Johnson Pharmaceutical Research and Development

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50119812BDBM50119812(1N-{4-[6-chloro-16-methyl-(12S)-2,10-diazatetracyc...)
Affinity DataIC50: 5nMAssay Description:Inhibition of [3H]Arg-vasopressin binding to recombinant human vasopressin V1a receptorMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetVasopressin V2 receptor(Human)
Johnson and Johnson Pharmaceutical Research and Development

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50065115BDBM50065115(N-[4-(5H,11H-Benzo[e]pyrrolo[1,2-a][1,4]diazepine-...)
Affinity DataIC50: 5nMAssay Description:Inhibition of AVP mediated activation of human vasopressin V2 receptor expressed in HEK293 cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetVasopressin V2 receptor(Human)
Johnson and Johnson Pharmaceutical Research and Development

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50119814BDBM50119814(1N-{4-[16-ethyl-2,10-diazatetracyclo[11.2.1.02,12....)
Affinity DataIC50: 6nMAssay Description:Inhibition of AVP mediated activation of human vasopressin V2 receptor expressed in HEK293 cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetVasopressin V2 receptor(Human)
Johnson and Johnson Pharmaceutical Research and Development

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50119813BDBM50119813(1N-{4-[6-chloro-16-methyl-(12S)-2,10-diazatetracyc...)
Affinity DataIC50: 7nMAssay Description:Inhibition of AVP mediated activation of human vasopressin V2 receptor expressed in HEK293 cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetVasopressin V2 receptor(Human)
Johnson and Johnson Pharmaceutical Research and Development

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50119815BDBM50119815(3-chloro-4-[16-methyl-(12S)-2,10-diazatetracyclo[1...)
Affinity DataKi:  9nMAssay Description:Inhibition of AVP mediated activation of human vasopressin V2 receptor expressed in HEK293 cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetVasopressin V2 receptor(Human)
Johnson and Johnson Pharmaceutical Research and Development

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50119813BDBM50119813(1N-{4-[6-chloro-16-methyl-(12S)-2,10-diazatetracyc...)
Affinity DataKi:  9nMAssay Description:Inhibition of AVP mediated activation of human vasopressin V2 receptor expressed in HEK293 cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetVasopressin V2 receptor(Human)
Johnson and Johnson Pharmaceutical Research and Development

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50119812BDBM50119812(1N-{4-[6-chloro-16-methyl-(12S)-2,10-diazatetracyc...)
Affinity DataIC50: 10nMAssay Description:Inhibition of [3H]Arg-vasopressin binding to recombinant human vasopressin V2 receptorMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetVasopressin V2 receptor(Human)
Johnson and Johnson Pharmaceutical Research and Development

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50119807BDBM50119807(1N-{4-[6-chloro-16-methyl-(12S)-2,10-diazatetracyc...)
Affinity DataKi:  13nMAssay Description:Inhibition of AVP mediated activation of human vasopressin V2 receptor expressed in HEK293 cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetVasopressin V2 receptor(Human)
Johnson and Johnson Pharmaceutical Research and Development

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50119811BDBM50119811(1N-{4-[6-chloro-16-ethyl-(12S)-2,10-diazatetracycl...)
Affinity DataIC50: 13nMAssay Description:Inhibition of AVP mediated activation of human vasopressin V2 receptor expressed in HEK293 cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetVasopressin V2 receptor(Human)
Johnson and Johnson Pharmaceutical Research and Development

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50119816BDBM50119816(3-chloro-4-[16-methyl-(12R)-2,10-diazatetracyclo[1...)
Affinity DataIC50: 15nMAssay Description:Inhibition of [3H]Arg-vasopressin binding to recombinant human vasopressin V2 receptorMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetVasopressin V2 receptor(Human)
Johnson and Johnson Pharmaceutical Research and Development

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50119819BDBM50119819(3-chloro-4-[16-ethyl-(12S)-2,10-diazatetracyclo[11...)
Affinity DataIC50: 19nMAssay Description:Inhibition of AVP mediated activation of human vasopressin V2 receptor expressed in HEK293 cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetVasopressin V1a receptor(Human)
Johnson and Johnson Pharmaceutical Research and Development

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50119807BDBM50119807(1N-{4-[6-chloro-16-methyl-(12S)-2,10-diazatetracyc...)
Affinity DataKi:  23nMAssay Description:Inhibition of AVP mediated activation of human vasopressin V1a receptor expressed in HEK293 cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetVasopressin V1a receptor(Human)
Johnson and Johnson Pharmaceutical Research and Development

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50119815BDBM50119815(3-chloro-4-[16-methyl-(12S)-2,10-diazatetracyclo[1...)
Affinity DataIC50: 24nMAssay Description:Inhibition of [3H]Arg-vasopressin binding to recombinant human vasopressin V1a receptorMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetVasopressin V1a receptor(Human)
Johnson and Johnson Pharmaceutical Research and Development

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50119807BDBM50119807(1N-{4-[6-chloro-16-methyl-(12S)-2,10-diazatetracyc...)
Affinity DataIC50: 24nMAssay Description:Inhibition of [3H]Arg-vasopressin binding to recombinant human vasopressin V1a receptorMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetVasopressin V2 receptor(Human)
Johnson and Johnson Pharmaceutical Research and Development

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50119810BDBM50119810(1N-{4-[6-chloro-16-methyl-(12S)-2,10-diazatetracyc...)
Affinity DataIC50: 26nMAssay Description:Inhibition of [3H]Arg-vasopressin binding to recombinant human vasopressin V2 receptorMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetVasopressin V2 receptor(Human)
Johnson and Johnson Pharmaceutical Research and Development

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50119817BDBM50119817(OPC-31260 | 2-Methyl-N-[4-(2,3,4,5-tetrahydro-benz...)
Affinity DataIC50: 28nMAssay Description:Inhibition of [3H]Arg-vasopressin binding to recombinant human vasopressin V2 receptorMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetVasopressin V2 receptor(Human)
Johnson and Johnson Pharmaceutical Research and Development

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50119809BDBM50119809(3-chloro-4-[6-chloro-16-methyl-(12S)-2,10-diazatet...)
Affinity DataIC50: 30nMAssay Description:Inhibition of AVP mediated activation of human vasopressin V2 receptor expressed in HEK293 cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetVasopressin V2 receptor(Human)
Johnson and Johnson Pharmaceutical Research and Development

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50119816BDBM50119816(3-chloro-4-[16-methyl-(12R)-2,10-diazatetracyclo[1...)
Affinity DataKi:  30nMAssay Description:Inhibition of AVP mediated activation of human vasopressin V2 receptor expressed in HEK293 cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetVasopressin V2 receptor(Human)
Johnson and Johnson Pharmaceutical Research and Development

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50119812BDBM50119812(1N-{4-[6-chloro-16-methyl-(12S)-2,10-diazatetracyc...)
Affinity DataKi:  32nMAssay Description:Inhibition of AVP mediated activation of human vasopressin V2 receptor expressed in HEK293 cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetVasopressin V1a receptor(Human)
Johnson and Johnson Pharmaceutical Research and Development

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50119811BDBM50119811(1N-{4-[6-chloro-16-ethyl-(12S)-2,10-diazatetracycl...)
Affinity DataIC50: 35nMAssay Description:Inhibition of [3H]Arg-vasopressin binding to recombinant human vasopressin V1a receptorMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetVasopressin V1a receptor(Human)
Johnson and Johnson Pharmaceutical Research and Development

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50119809BDBM50119809(3-chloro-4-[6-chloro-16-methyl-(12S)-2,10-diazatet...)
Affinity DataIC50: 35nMAssay Description:Inhibition of [3H]Arg-vasopressin binding to recombinant human vasopressin V1a receptorMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetVasopressin V1a receptor(Human)
Johnson and Johnson Pharmaceutical Research and Development

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50119813BDBM50119813(1N-{4-[6-chloro-16-methyl-(12S)-2,10-diazatetracyc...)
Affinity DataKi:  40nMAssay Description:Inhibition of AVP mediated activation of human vasopressin V1a receptor expressed in HEK293 cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetVasopressin V1a receptor(Human)
Johnson and Johnson Pharmaceutical Research and Development

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50119808BDBM50119808(1N-{4-[6-chloro-16-ethyl-(12S)-2,10-diazatetracycl...)
Affinity DataIC50: 59nMAssay Description:Inhibition of [3H]Arg-vasopressin binding to recombinant human vasopressin V1a receptorMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetVasopressin V1a receptor(Human)
Johnson and Johnson Pharmaceutical Research and Development

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50119810BDBM50119810(1N-{4-[6-chloro-16-methyl-(12S)-2,10-diazatetracyc...)
Affinity DataIC50: 68nMAssay Description:Inhibition of [3H]Arg-vasopressin binding to recombinant human vasopressin V1a receptorMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetVasopressin V2 receptor(Human)
Johnson and Johnson Pharmaceutical Research and Development

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50119808BDBM50119808(1N-{4-[6-chloro-16-ethyl-(12S)-2,10-diazatetracycl...)
Affinity DataIC50: 72nMAssay Description:Inhibition of AVP mediated activation of human vasopressin V2 receptor expressed in HEK293 cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetVasopressin V2 receptor(Human)
Johnson and Johnson Pharmaceutical Research and Development

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50065115BDBM50065115(N-[4-(5H,11H-Benzo[e]pyrrolo[1,2-a][1,4]diazepine-...)
Affinity DataKi:  90nMAssay Description:Inhibition of AVP mediated activation of human vasopressin V2 receptor expressed in HEK293 cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetVasopressin V1a receptor(Human)
Johnson and Johnson Pharmaceutical Research and Development

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50119815BDBM50119815(3-chloro-4-[16-methyl-(12S)-2,10-diazatetracyclo[1...)
Affinity DataKi:  130nMAssay Description:Inhibition of AVP mediated activation of human vasopressin V1a receptor expressed in HEK293 cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetVasopressin V1a receptor(Human)
Johnson and Johnson Pharmaceutical Research and Development

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50119812BDBM50119812(1N-{4-[6-chloro-16-methyl-(12S)-2,10-diazatetracyc...)
Affinity DataKi:  130nMAssay Description:Inhibition of AVP mediated activation of human vasopressin V1a receptor expressed in HEK293 cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetVasopressin V1a receptor(Human)
Johnson and Johnson Pharmaceutical Research and Development

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50065115BDBM50065115(N-[4-(5H,11H-Benzo[e]pyrrolo[1,2-a][1,4]diazepine-...)
Affinity DataIC50: 150nMAssay Description:Inhibition of [3H]Arg-vasopressin binding to recombinant human vasopressin V1a receptorMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetVasopressin V2 receptor(Human)
Johnson and Johnson Pharmaceutical Research and Development

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50119817BDBM50119817(OPC-31260 | 2-Methyl-N-[4-(2,3,4,5-tetrahydro-benz...)
Affinity DataKi:  160nMAssay Description:Inhibition of AVP mediated activation of human vasopressin V2 receptor expressed in HEK293 cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetVasopressin V2 receptor(Human)
Johnson and Johnson Pharmaceutical Research and Development

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50119810BDBM50119810(1N-{4-[6-chloro-16-methyl-(12S)-2,10-diazatetracyc...)
Affinity DataKi:  180nMAssay Description:Inhibition of AVP mediated activation of human vasopressin V2 receptor expressed in HEK293 cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetVasopressin V1a receptor(Human)
Johnson and Johnson Pharmaceutical Research and Development

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50119817BDBM50119817(OPC-31260 | 2-Methyl-N-[4-(2,3,4,5-tetrahydro-benz...)
Affinity DataIC50: 250nMAssay Description:Inhibition of [3H]Arg-vasopressin binding to recombinant human vasopressin V1a receptorMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetVasopressin V2 receptor(Human)
Johnson and Johnson Pharmaceutical Research and Development

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50119811BDBM50119811(1N-{4-[6-chloro-16-ethyl-(12S)-2,10-diazatetracycl...)
Affinity DataKi:  520nMAssay Description:Inhibition of AVP mediated activation of human vasopressin V2 receptor expressed in HEK293 cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetVasopressin V1a receptor(Human)
Johnson and Johnson Pharmaceutical Research and Development

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50119811BDBM50119811(1N-{4-[6-chloro-16-ethyl-(12S)-2,10-diazatetracycl...)
Affinity DataKi:  620nMAssay Description:Inhibition of AVP mediated activation of human vasopressin V1a receptor expressed in HEK293 cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetVasopressin V1a receptor(Human)
Johnson and Johnson Pharmaceutical Research and Development

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50119817BDBM50119817(OPC-31260 | 2-Methyl-N-[4-(2,3,4,5-tetrahydro-benz...)
Affinity DataKi:  890nMAssay Description:Inhibition of AVP mediated activation of human vasopressin V1a receptor expressed in HEK293 cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetVasopressin V1a receptor(Human)
Johnson and Johnson Pharmaceutical Research and Development

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50119810BDBM50119810(1N-{4-[6-chloro-16-methyl-(12S)-2,10-diazatetracyc...)
Affinity DataKi:  2.60E+3nMAssay Description:Inhibition of AVP mediated activation of human vasopressin V1a receptor expressed in HEK293 cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetCytochrome P450 2C9(Human)
Johnson and Johnson Pharmaceutical Research and Development

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50119807BDBM50119807(1N-{4-[6-chloro-16-methyl-(12S)-2,10-diazatetracyc...)
Affinity DataIC50: 7.40E+3nMAssay Description:Inhibition of cytochrome P450 2C9More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed